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Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao最新文献

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Production and application of monoclonal antibodies to polyamine--spermidine McAb. 多胺-亚精胺单克隆抗体的制备及应用。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1989-01-01
D B Wang, Z Z Chen, Z F Fan, M H Cao, Z Y Zhu, P Su
{"title":"Production and application of monoclonal antibodies to polyamine--spermidine McAb.","authors":"D B Wang, Z Z Chen, Z F Fan, M H Cao, Z Y Zhu, P Su","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 1","pages":"60"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13850001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A multivariate analysis of pathologic factors influencing prognosis of colorectal cancer in 1067 cases. 1067例影响结直肠癌预后的病理因素的多因素分析
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1989-01-01
L Li, Y P Wu, Y Y Liu, X R Yu, Z R Chen
{"title":"A multivariate analysis of pathologic factors influencing prognosis of colorectal cancer in 1067 cases.","authors":"L Li,&nbsp;Y P Wu,&nbsp;Y Y Liu,&nbsp;X R Yu,&nbsp;Z R Chen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Multivariate analysis (risk state analysis) was performed to evaluate the single and joint effects of pathologic variables on the survivals of 1067 cases of colorectal carcinoma. Nineteen of the twenty-eight variables analyzed were found to have statistically significant prognostic value, with over half having a strong influence on prognosis. The first seven, ranked in order of their effects on survival, are metastasis in lymph nodes, depth of invasion, histologic grading, lymphocyte infiltration of the cancer, GH (immune response in regional lymph nodes), growth pattern and fibrous proliferation around the cancer. The joint effects of combinations of these major variables are even more striking than those of single ones.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 1","pages":"38-42"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13852313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical effect of immunologic bacterio-vaccine on essential hypertension (100 cases report). 免疫细菌疫苗治疗原发性高血压的临床效果(附100例报告)。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1989-01-01
B K Luo, D Z Liu
{"title":"Clinical effect of immunologic bacterio-vaccine on essential hypertension (100 cases report).","authors":"B K Luo,&nbsp;D Z Liu","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 1","pages":"58-9"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13852315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Solubilization and purification of opioid receptor molecules of rat brain. 大鼠脑阿片受体分子的增溶纯化。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1989-01-01
Y C Jin, C Y Ye, Y Li, C L Suo, L Y Li, M Q Liu, X M Jin, Z M Mao
{"title":"Solubilization and purification of opioid receptor molecules of rat brain.","authors":"Y C Jin,&nbsp;C Y Ye,&nbsp;Y Li,&nbsp;C L Suo,&nbsp;L Y Li,&nbsp;M Q Liu,&nbsp;X M Jin,&nbsp;Z M Mao","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A P2 membrane preparation of rat brain (without cerebellum) was solubilized with CHAPS in Tris containing DTT and trypsin inhibitor. Two opiate ligands, 10b and 10cd, prepared by Liu et al, were employed consecutively in affinity chromatography, from which OPR's were eluted with Nx. The eluate was subsequently passed through a WGA affinity column and the OPR's eluted with N-GluNAc. This eluate was further purified and concentrated by preparative granular gel isoelectric focusing on SG200. Two protein peaks appeared separately at pH 5 and 7.8. The eluates from both peaks were examined for protein contents using the silver staining method, and binding activity was measured by RRA with 3H-etor. The results revealed that both samples contained active OPR purified to over 80,000 fold. The Mr was estimated by gel filtration to be 52 kD and 42 kD for OPR in the pH 5 and pH 7.8 samples respectively. OPR in the pH 5 sample have been determined to be of mu-type by their binding activity with 3H-ohm.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13684261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Crow-Fukase syndrome--a case report. 克劳-福田综合征1例报告。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1989-01-01
W B Xu, B Q Cai, W C Luo, Z Y Tong, M X Tan, Y P Guo
{"title":"Crow-Fukase syndrome--a case report.","authors":"W B Xu,&nbsp;B Q Cai,&nbsp;W C Luo,&nbsp;Z Y Tong,&nbsp;M X Tan,&nbsp;Y P Guo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 4","pages":"237-8"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13773992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes of neutrophil elastase and alpha 1-antitrypsin in systemic lupus erythematosus. 中性粒细胞弹性酶和α 1-抗胰蛋白酶在系统性红斑狼疮中的变化。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1989-01-01
X H Zhang, Y H Yan, Z Q Liang, X L Cui, M Jiang
{"title":"Changes of neutrophil elastase and alpha 1-antitrypsin in systemic lupus erythematosus.","authors":"X H Zhang,&nbsp;Y H Yan,&nbsp;Z Q Liang,&nbsp;X L Cui,&nbsp;M Jiang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Contents of HNE and alpha 1-AT and the positive rates of PMN-Ab in patients with SLE were measured and tested by ELISA, immunodiffusion and protein-A rosette, respectively, and it was found that plasma HNE content was significantly higher in patients with SLE (61.0 +/- 13.9 ng/ml) than in normal controls (33.7 +/- 6.7 ng/ml, P less than 0.001), while plasma alpha 1-AT in patients with SLE (2.79 +/- 0.47 mg/ml) was similar to that in normal controls (2.55 +/- 0.38 mg/ml, P greater than 0.6). The positive rate of PMN-Ab in SLE (9.8 +/- 6.5) was also significantly higher than that in normal (0.17 +/- 0.2%, P less than 0.001). The results suggest that there is an imbalance between plasma HNE and alpha 1-AT in SLE regardless of WBC or the positive rate of PMN-Ab, with this imbalance probably being due to activation of neutrophils following multiorgan damage of SLE.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 1","pages":"26-9"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13924011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studies on social medicine and leprosy in east China. 中国东部地区社会医学与麻风病研究。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1989-01-01
H D Ma, G Y Ye, H W Shu, C Jiang, D S Zhou
{"title":"Studies on social medicine and leprosy in east China.","authors":"H D Ma,&nbsp;G Y Ye,&nbsp;H W Shu,&nbsp;C Jiang,&nbsp;D S Zhou","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Leprosy is a disease in which the social, economic, cultural and environmental factors play an important role in occurrence, spread, control, eradication and rehabilitation. Eliminating the unfavourable factors hindering leprosy control can make achieving the goal of basic eradication of leprosy in China before the end of this century possible. For this reason, since 1984 we have carried out systematic studies of the social aspects of leprosy in Baoying County, a former high-endemic area in Jiangsu Province of East China, where the endemicity of leprosy is nearing full control.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 2","pages":"61-4"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13937487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of rhodamine 123 and total glycosides from tripterygium wilfordii (GTW) on ultrastructures, survival and fertilizing capacity of human sperm in vitro. 罗丹明123和雷公藤总苷对体外精子超微结构、存活和受精能力的影响。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1989-01-01
J B Zhang, Z Q Han, J Yuan, L S Chen, Y H Zou, S P Xue
{"title":"Effect of rhodamine 123 and total glycosides from tripterygium wilfordii (GTW) on ultrastructures, survival and fertilizing capacity of human sperm in vitro.","authors":"J B Zhang,&nbsp;Z Q Han,&nbsp;J Yuan,&nbsp;L S Chen,&nbsp;Y H Zou,&nbsp;S P Xue","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Human sperms were treated with rhodamine 123 or GTW in vitro. Comparisons were made of survival, fertilizing capacity and ultrastructures of sperms which had been exposed to different concentrations and treatment durations of the agents. The results showed that no prominent change could be observed when treated with lower doses. However, at higher concentrations of rhodamine 123, mitochondria were found to be swollen, vacuolated and deranged instead of surrounding the flagellar axoneme in the normal spiral way, and the mitochondrial cristae were broken or had disappeared. In some sperms, cracks at the flagellar axoneme and concave defects in the acrosome were seen. The sperms lost their fertilizing capacity, though some of them were still alive, whereas the sperms treated with GTW showed no morphological damage and maintained their ability to penetrate the hamster egg. Our results suggest that rhodamine 123 is a prospect in the search for an anti-sperm contraceptive.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 2","pages":"80-4"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13937490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A study of event-related potential P300 in cerebral infarction. 脑梗死事件相关电位P300的研究。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1989-01-01
X F Tang, Y N Huang, L Y Cui, H Du, B H Li, L N Zhang
{"title":"A study of event-related potential P300 in cerebral infarction.","authors":"X F Tang,&nbsp;Y N Huang,&nbsp;L Y Cui,&nbsp;H Du,&nbsp;B H Li,&nbsp;L N Zhang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>N1, P2 and P300 potentials were studied in 20 cases of cerebral infarction and 47 healthy controls with the standard technique of auditory event-related potentials. Healthy controls of both sexes, different ages, education levels and cognitive capacity did not show apparent differences in the latency of P300 (P greater than 0.05, respectively). The patient group, however, revealed a significant (P less than 0.001) prolongation of latency of P300 (means = 409.6 +/- 50 ms) as compared with 28 well matched healthy subjects (means = 337.7 +/- 24 ms). Although there was a slightly lower amplitude of P300 in the patient group, the difference between control and patient groups was not significant (P greater than 0.05). There was a significant difference in the Cognitive Capacity Screening Examination findings between control and patient groups (P less than 0.01), but it seems that evaluation of the cognition-related latency of P300 may be more objective and sensitive in distinguishing between organic and cognitive distress (P less than 0.001).</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 4","pages":"205-9"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13773986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prolonged hemopoiesis of murine bone marrow derived epithelioid cells in vitro. 小鼠骨髓上皮样细胞体外长时间造血的研究。
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1989-01-01
Z X Song, S L Qi, Y X Ma, W P Li, J H Liu, J Fu
{"title":"Prolonged hemopoiesis of murine bone marrow derived epithelioid cells in vitro.","authors":"Z X Song,&nbsp;S L Qi,&nbsp;Y X Ma,&nbsp;W P Li,&nbsp;J H Liu,&nbsp;J Fu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We previously reported the isolation of a murine bone marrow derived stromal cell line, TC-1, and two sublines derived from this line. The monolayer of one subline, TC-1-C-3, directly supported the growth of nonadherent marrow cells in Dexter culture system for eight weeks. We report here the mechanism of the stromal cell effect on hemopoiesis in a long-term bone marrow culture system. When the hemopoietic blasts attach to the TC-1-C-3 cells, they are surrounded by the stromal cell cytoplasm within two hours and develop into cell clusters in a week. The developing hemopoietic cells show cell differentiation towards the granulocytic lineage. A key function of the epithelioid stromal cell, then, is to provide a 'niche' or 'envelope' for stem cells which supports long-term hemopoiesis in the Dexter culture system.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 1","pages":"8-12"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13850002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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