Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao最新文献
S G Chen, B L Chang, S Meerbaum, J K Drury, E Corday
{"title":"The pattern of delivery and distribution of coronary venous retroinfusate in canine hearts.","authors":"S G Chen, B L Chang, S Meerbaum, J K Drury, E Corday","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The delivery and distribution of retroinfusate premixed with radionuclide microspheres (15 microns) in the coronary venous system of canine hearts was studied in in vitro and in vivo experiments. Results showed that about 51-85% of the retroinfusate was shunted directly by vessels greater than 15 microns in diameter to the right heart in cases of isolated heart study, while the remaining 21-42% passed through intramyocardial capillaries with obvious nutritional effects. In the closed-chest experiments, 95% of the retroinfusate was bypassed to the right heart; less than 5% went through the intramyocardial microcirculation system. Intramyocardial distribution pattern of the retroinfusate indicated a predominant supply to the left ventricular free wall. There was a preferential distribution of the retroinfusate to the ischemic area with a subendo subepi blood flow ratio of up to 1.79 +/- 0.21 post-LAD occlusion.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 1","pages":"19-25"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13852311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Design and clinical application of a dual channel electrical stimulator for scoliosis.","authors":"Q B Ye, Z K Wu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fifteen patients with scoliosis were treated by a dual channel surface stimulator made in China. After an 18.5 month treatment, their curves decreased by 3 degrees to 15 degrees. The effective rate was 93.3%.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 4","pages":"210-4"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13773987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Studies on the mechanism of anemia in rodent malaria.","authors":"Y L Wu, Q Yu, W L Li, E X Liu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The underlying cause of anemia is one of the problems to be solved in malaria research. Many factors are involved in reducing the quantity of uninfected red blood cells (RBC) in addition to those infected RBC destroyed by malaria parasites. In the Plasmodium yoelii (P.y.)-mouse model, the amount of [51Cr]-labelled normal mouse RBC destroyed in peripheral blood as well as the quantity phagocytized by spleen cells during acute and chronic infection in vivo is reported in this paper. Our results show that compensatory enlargement of the spleen, which cleans up a large amount of the damaged uninfected RBC, may be the major cause of anemia in chronic malaria infection. In acute malaria infection destruction of uninfected RBC in peripheral circulation is higher than that in normal mice. Neither malaria antigen, mouse autoantibody nor immune complex was detected on the surface of normal RBC from infected mice using indirect immunofluorescence assay (IFA) or [3H]-isoleucine-labelled P.y. antigen (P.y.Ag) in vitro. This suggests that malaria immune complexes do not play an important part in RBC destruction in circulating blood. Since no obvious hemolysis was observed by mixing RBC with P.y. culture supernatant in vitro, it is possible that physical and chemical changes in uninfected RBC induced by malaria metabolites are the prerequisite for their destruction in circulating blood in vivo. Hemolysis occurs due to external stresses, such as those incurred when damaged RBC run into each other in the blood stream or when they change their shape to pass through capillaries.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 2","pages":"102-5"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13936034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Z Chen, F R Chen, J X Guo, M J Mao, G H Zhou, W D Yan, D Y Xie
{"title":"Clinical application of coronary laser angioplasty during coronary bypass surgery.","authors":"M Z Chen, F R Chen, J X Guo, M J Mao, G H Zhou, W D Yan, D Y Xie","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Laser irradiation offers the potential of removing atherosclerotic plaques from blood vessels. We used the Nd:YAG laser to treat coronary atherosclerotic obstruction in patients undergoing coronary bypass. Of the 7 patients treated, all were successfully recanalized without damage to the artery wall (a mild hematoma developed in 1 case), and follow-up examination showed patency 4 months after operation. We conclude that Nd:YAG laser shows promise for the treatment of atherosclerotic obstructions, but more study is needed before wide clinical application is justified.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 2","pages":"65-7"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13937488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y L Li, S Y Hsu, H F Hsu, J W Osborne, H Robinson, Y Ohnishi
{"title":"Autoradiographic study of the attrition of migrating schistosomula in the skin of mice. I. Mice immunized with highly X-irradiated Schistosoma mansoni cercariae.","authors":"Y L Li, S Y Hsu, H F Hsu, J W Osborne, H Robinson, Y Ohnishi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The migratory pattern in naive mice of Schistosoma mansoni cercariae X-irradiated with OkR, 12kR, or 48rR has been investigated with compressed organ autoradiography. Three groups of 69 mice each were infected with 75Se-labelled cercariae. The skin at the site of infection, as well as the entire lungs and liver were removed from infected mice daily from 1-21d, on 24d, and on 28d; tissues were then processed for autoradiography. Autoradiographic analysis of migratory patterns showed that the schistosomula derived from nonattenuated cercariae passed quickly from the skin to the lungs and at a moderate rate from the lungs to the liver. Schistosomula derived from 12kR-irradiated cercariae were delayed in passing from the skin to the lungs and from the lungs to the liver, so that many remained in the lungs and died there, while only a few died in the skin or liver. Schistosomula derived from 48kR-irradiated cercariae remained mainly in the skin, rarely reached the lungs and were never found in the liver. This study indicates that immunization with 48kR-irradiated cercariae will cause no significant lesions in the lungs or liver.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 3","pages":"153-6"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13738100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determination of avicularin in Polygonum aviculare L. by square wave polarography.","authors":"X Q Zhang, L S Xu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A method for the determination of avicularin in Polygonum aviculare L. is described. Square wave polarography (SWP) with a static mercury drop electrode was used to observe the reduction of avicularin. The supporting electrolyte was an acetate buffer solution of pH 4. Avicularin gives a well-defined peak at a potential of -1.30 V (vs. Ag/AgCl). An excellent linear relationship was obtained between the concentration (1.20-3.59 x 10(-6) mol/L) and peak current. The method can be used to analyze small amounts of sample.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 4","pages":"193-5"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13773983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of habitual dislocation of the temporomandibular joint with subsynovial injection of sclerosant through arthroscope.","authors":"W L Qiu, Q Ha, Q G Hu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Five patients with habitual dislocation of the temporomandibular joint (TMJ), failing in conservative therapy, were treated with subsynovial injections of sclerosant through an arthroscope, and this treatment was proved to be effective over the short-term. Compared with operation, this method is easily performed and produces less damage and no significant sequelae, but the long-term effects have yet to be observed.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 4","pages":"196-9"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13773984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Observation on the effect of sodium nitroprusside and dopamine on acute myocardial infarction during hospitalization.","authors":"F Q Liu, S Y Fu, R Z Wang, L F Wang, J S Zhang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>With improvements in cardiac monitoring systems and the effective treatment of arrhythmias, the case-fatality rate of acute myocardial infarction (AMI) has been declining gradually since 1972. But since 1977, despite the great efforts of medical workers in many countries, the lowest case-fatality rate of AMI has still been about 10%. Over many years, our institute has carried out research aimed at improving the treatment of AMI. However, in our institute the case-fatality rate has fluctuated between 15 and 20% in recent years. From March 1986 to January 1987 we adopted a sodium nitroprusside and dopamine intravenous drip in the treatment of 92 cases of AMI and achieved a hospitalization period AMI case-fatality rate of less than 5% (2 patients died). The treatment methods and relevant materials are reported here.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 4","pages":"200-4"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13773985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rehepatectomy for treating primary liver cancer.","authors":"H Chen, M C Wu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>From January 1960 to June 1987, 41 cases underwent reoperation for relapse of liver cancer. Hepatectomy was performed twice in 39 cases, three and four times each in one case. The 1,3 and 5-year survival rates after the first operation were 100%, 69.58% and 54.68% respectively, while those after the second operation were 75.0%, 34.62% and 34.62% respectively. The preliminary results of rehepatectomy are thus encouraging. The indicators for reintervention, types of operation, prophylactic measures against tumor recurrence and metastases, and evaluation of rehapatectomy are discussed.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 2","pages":"68-71"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13696806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Z Ye, A D Zhang, H P Shi, S M Zhao, H Y Luo, L F Yuan, S W Ma, S H Li, Z Y Cheng, Y Zhao
{"title":"Analysis of 4628 cases in the genetic counselling clinic of PUMC Hospital.","authors":"L Z Ye, A D Zhang, H P Shi, S M Zhao, H Y Luo, L F Yuan, S W Ma, S H Li, Z Y Cheng, Y Zhao","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An analysis of 4628 cases in the genetic counseling clinic of PUMC Hospital is reported. Althogether 966 cases (20.87%) were diagnosed as having genetic diseases, among whom were 436 cases (45.13%) with chromosome aberrations, 161 (16.67%) with inherited metabolic diseases, 111 (11.49%) with constitutional bone diseases, 103 (10.66%) with various kinds of genetic neuromuscular diseases, 109 (11.28%) with different dysmorphic syndromes, and 46 (4.76%) with different kinds of genetic dermatoses and oculopathies. 973 cases (21.02%) were suspected to suffer from some form of genetic disease, but this could not be proved due to a lack of specific diagnostic methods. 2689 cases (58.10%) were found to be unaffected by inherited diseases. Some of the experiences gained and the key role of genetic counselling in family planning are briefly discussed.</p>","PeriodicalId":77596,"journal":{"name":"Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao","volume":"4 3","pages":"126-30"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13737384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}