1067例影响结直肠癌预后的病理因素的多因素分析

Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao Pub Date : 1989-01-01

L Li, Y P Wu, Y Y Liu, X R Yu, Z R Chen

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引用次数: 0

摘要

采用多因素分析(风险状态分析)评价1067例结直肠癌患者的单一及联合病理变量对生存率的影响。分析的28个变量中有19个被发现具有统计学上显著的预后价值，其中一半以上对预后有很强的影响。根据对生存的影响，前7个因素依次是淋巴结转移、浸润深度、组织学分级、肿瘤淋巴细胞浸润、GH(区域淋巴结免疫反应)、肿瘤周围的生长模式和纤维增生。这些主要变量组合的共同影响甚至比单个变量的共同影响更为显著。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A multivariate analysis of pathologic factors influencing prognosis of colorectal cancer in 1067 cases.

Multivariate analysis (risk state analysis) was performed to evaluate the single and joint effects of pathologic variables on the survivals of 1067 cases of colorectal carcinoma. Nineteen of the twenty-eight variables analyzed were found to have statistically significant prognostic value, with over half having a strong influence on prognosis. The first seven, ranked in order of their effects on survival, are metastasis in lymph nodes, depth of invasion, histologic grading, lymphocyte infiltration of the cancer, GH (immune response in regional lymph nodes), growth pattern and fibrous proliferation around the cancer. The joint effects of combinations of these major variables are even more striking than those of single ones.

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Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao

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