American Journal of Tropical Medicine and Hygiene最新文献_第7页

Comorbid Guillain-Barré Syndrome and Tuberculosis: A Case Study and Global Perspective.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-02-25 DOI: 10.4269/ajtmh.24-0623

Gui-Hua Yang, Tu-Er Wan, Hui-Ping Song, Hui-Wen Song

{"title":"Comorbid Guillain-Barré Syndrome and Tuberculosis: A Case Study and Global Perspective.","authors":"Gui-Hua Yang, Tu-Er Wan, Hui-Ping Song, Hui-Wen Song","doi":"10.4269/ajtmh.24-0623","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0623","url":null,"abstract":"A 27-year-old man presented with a cough and progressive limb weakness. Initially diagnosed with pulmonary tuberculosis, he showed improvement in his cough after antituberculosis treatment (ATT). However, he subsequently developed worsening weakness and numbness in his lower limbs, leading to mobility loss and difficulty swallowing. A comprehensive diagnostic evaluation, including computed tomography of the lung, cranial magnetic resonance imaging, cerebrospinal fluid analysis, and electromyography, confirmed concurrent diagnoses of tuberculosis (TB) and Guillain-Barré syndrome (GBS). Treatment included immunoglobulin and corticosteroid therapy; however, his symptoms persisted, progressing to respiratory failure that required endotracheal intubation and plasma exchange therapy. After these interventions, his condition gradually improved, and he continued ATT, achieving a favorable recovery. A literature review identified 15 countries reporting cases of GBS associated with TB, with the highest incidence in India. Although most cases showed a positive prognosis, mortality rates were elevated in patients with comorbid TB and GBS compared to those with GBS alone.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143497704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mitigating Resistance to Malaria Treatments in Sub-Saharan Africa Requires More than New Drugs.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-02-25 DOI: 10.4269/ajtmh.24-0781

Lawrence M Barat

引用次数: 0

Cardiopulmonary Echinococcus Infection.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-02-25 DOI: 10.4269/ajtmh.24-0761

Naama A R Almaazmi, Zainab Alshebli, Nour Alneyadi, Abdulla S AlAmri, Amna Z Ahmad, Ahmed A K AlHammadi

引用次数: 0

Rotavirus Infection in Children Suffering from Diarrhea in Patna, Bihar Region, India: A Hospital-Based Study.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-02-25 DOI: 10.4269/ajtmh.24-0543

Neetesh Jindal, Ashish Kumar, Ashiq Hussain Bhat, Major Madhukar, Roshan Kamal Topno, Krishna Pandey, Ganesh Chandra Sahoo

{"title":"Rotavirus Infection in Children Suffering from Diarrhea in Patna, Bihar Region, India: A Hospital-Based Study.","authors":"Neetesh Jindal, Ashish Kumar, Ashiq Hussain Bhat, Major Madhukar, Roshan Kamal Topno, Krishna Pandey, Ganesh Chandra Sahoo","doi":"10.4269/ajtmh.24-0543","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0543","url":null,"abstract":"Rotavirus (RV) is a leading cause of severe gastroenteritis in infants and young children, often resulting in dehydration and hospitalization. Although global data on RV is well-documented, there is limited information on its prevalence and genetic diversity in Bihar, India. This study aimed to investigate the prevalence of RV infections in the patient, from January 2021 to June 2024, and assess the associated molecular and epidemiological patterns. In this retrospective study conducted at the Rajendra Memorial Research Institute of Medical Sciences, Patna, 1,820 stool samples from patients suspected of RV infection were collected. Enzyme immunoassays were used to detect RV antigens, and positive samples were confirmed by real-time polymerase chain reaction targeting the VP4, VP6, and VP7 genes. Phylogenetic analysis was performed to examine genetic diversity. Results showed a 10% positivity rate for RV, with 5% showing equivocal results. The highest prevalence was in the 6-11 years age group (72 positive cases), followed by the 0-5 years group (62 positive cases). Prevalence decreased in older age groups, suggesting immunity through natural infection or vaccination. Phylogenetic analysis revealed distinct regional clusters and genetic variability between strains from Bihar and other parts of India, such as New Delhi and Kolkata. This study provides valuable baseline data on RV prevalence and genetic diversity in Bihar, emphasizing the need for vaccination and surveillance, particularly for younger children at higher risk. The observed genetic diversity suggests regional variations, highlighting the importance of continuous surveillance across India.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143497820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Behavior Change Intervention on Complementary Food Contamination in Rural Bangladesh: A Cluster-Randomized Controlled Trial.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-02-18 DOI: 10.4269/ajtmh.24-0336

Tarique Md Nurul Huda, Anna A Müller-Hauser, Shafinaz Sobhan, Shaheen Hossain, Jesmin Sultana, Mahbubur Rahman, Mohammad Aminul Islam, Om Prasad Gautam, Amanda S Wendt, Jillian L Waid, Sabine Gabrysch

{"title":"Effect of Behavior Change Intervention on Complementary Food Contamination in Rural Bangladesh: A Cluster-Randomized Controlled Trial.","authors":"Tarique Md Nurul Huda, Anna A Müller-Hauser, Shafinaz Sobhan, Shaheen Hossain, Jesmin Sultana, Mahbubur Rahman, Mohammad Aminul Islam, Om Prasad Gautam, Amanda S Wendt, Jillian L Waid, Sabine Gabrysch","doi":"10.4269/ajtmh.24-0336","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0336","url":null,"abstract":"Children in low-resource settings often consume microbially contaminated food, risking their health. We evaluated the impact of a food hygiene intervention on complementary food contamination in Bangladesh. A 3-year homestead food production intervention was complemented by an 8-month behavior change module to improve household food hygiene practices and evaluated in a cluster-randomized controlled trial, including a dedicated study measuring outcomes along the hygiene pathway to intestinal health. We used multilevel regression to assess the intervention's impact on microbial food contamination as well as food hygiene knowledge (n = 518) and reported practices (n = 531) among mothers of children 6-23 months of age. Complementary food samples were collected from 342 households with children 6-18 months of age and tested for Escherichia coli. Overall, 46% of food samples were contaminated with E. coli (43% intervention, 51% control), and there was no evidence that the intervention reduced food contamination (odds ratio: 0.65, 95% CI: 0.35-1.21). A higher proportion of intervention mothers could name all key food hygiene practices (23% intervention versus 1% control), had access to a basic handwashing station near the kitchen (24% versus 14%), reported washing hands before food preparation and child feeding (21% versus 8%), reported washing and storing feeding utensils safely (61% versus 49%), and reported preparing food fresh or reheating stored food (88% versus 79%) compared with control mothers. The intervention thus improved knowledge and reported food hygiene practices among mothers, but this improvement did not result in a substantial reduction of complementary food contamination.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eumycetoma on the Back.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-02-18 DOI: 10.4269/ajtmh.24-0699

Mamadou Ball, Dallas J Smith

引用次数: 0

Bilateral Pulmonary Cystic Lesions with Fatal Outcome Due to Echinococcosis.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-02-18 DOI: 10.4269/ajtmh.24-0511

Aman Elwadhi, Prateek Kumar Panda, Indar Kumar Sharawat

引用次数: 0

Cleaning and Disinfection Practices of Reused Alcohol-Based Hand Rub Containers in Health Care Settings: Evidence from Five Rural Districts in Uganda.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-02-18 DOI: 10.4269/ajtmh.24-0189

Fred Tusabe, Kanako Ishida, Francis Ocitti, Sauda Yapswale, Maureen Kesande, Herbert Isabirye, Judith Nanyondo, Victoria Trinies, Alexandra Medley, Mohammed Lamorde, David Berendes

{"title":"Cleaning and Disinfection Practices of Reused Alcohol-Based Hand Rub Containers in Health Care Settings: Evidence from Five Rural Districts in Uganda.","authors":"Fred Tusabe, Kanako Ishida, Francis Ocitti, Sauda Yapswale, Maureen Kesande, Herbert Isabirye, Judith Nanyondo, Victoria Trinies, Alexandra Medley, Mohammed Lamorde, David Berendes","doi":"10.4269/ajtmh.24-0189","DOIUrl":"https://doi.org/10.4269/ajtmh.24-0189","url":null,"abstract":"Local alcohol-based hand rub (ABHR) production systems in low-resource settings, such as in health care facilities (HCFs) in low- and middle-income countries, frequently reuse containers for storing and dispensing ABHR. Cleaning/disinfection (C/D) of ABHR containers is necessary to safely reuse them and is an integral part of the WHO's guidelines on local ABHR production. However, HCFs may not be aware of the need for C/D; combined with suboptimal implementation, this poses a risk of contamination of ABHR. As part of district-led ABHR production in HCFs in five rural districts in Uganda, we developed a standard operating procedure (SOP) for C/D of reused ABHR containers and provided on-site training for infection prevention and control personnel. Using in-person surveys, we assessed the availability of C/D supplies and equipment and the self-reported C/D practices before and after the training. At baseline, almost all (n = 90/91) HCFs reported reusing ABHR containers; 8% and 12% of HCFs routinely had all of the key C/D materials needed for adequately cleaning and disinfecting containers using chlorine and thermal disinfection methods, respectively. HCFs that reported adequately cleaning containers per the SOP increased from 3% (n = 2) at baseline to 18% (n = 16) after the training, whereas adequate disinfection increased from 0% (n = 0) to 5% (n = 5). All HCFs that performed disinfection reported using chlorine, and none reported using thermal disinfection. Improving access to C/D supplies, providing routine mentorship, and monitoring ABHR container C/D are needed to further improve C/D practices.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiological Characteristics of Severe Fever with Thrombocytopenia Syndrome.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-02-18 DOI: 10.4269/ajtmh.24-0616

Sakarn Charoensakulchai, Keita Matsuno, Emi E Nakayama, Tatsuo Shioda, Hisham A Imad

引用次数: 0

Mucosal Leishmaniasis in Tunisia: Observations from a Rare Case Report.

IF 1.9 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-02-18 DOI: 10.4269/ajtmh.24-0592

Hamed Chouaieb, Mohammad Akhoundi, Malika El Omri, Samar Ismail, Imen Khammari, Foued Bellazreg, Mouna Bellakhdher, Mohamed Abdelkefi, Wissem Hachfi, Akila Fathallah

引用次数: 0