American Journal of Tropical Medicine and Hygiene最新文献_第7页

Primary Cutaneous Nocardiosis of the Scrotum Following Presurgical Inguinal Shaving. 腹股沟剃须手术后阴囊原发性皮肤诺卡菌病。

IF 1.6 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-08-19 DOI: 10.4269/ajtmh.25-0285

Nathalia Chebli-de-Abreu, Júlia Amélia Ricci, Débora Dumont Cruz Nunes

引用次数: 0

Emerging Resistance in Anopheles stephensi Larvae to the Larvicide Temephos in Chennai, India. 钦奈地区斯氏按蚊幼虫对杀幼虫剂双硫磷的新抗性。

IF 1.6 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-08-19 DOI: 10.4269/ajtmh.25-0232

Sangamithra Ravishankaran, Shalu Thomas, Aswin Asokan, Johnson Amala Justin Nalapatty Anthonysamy, Manu Thomas Mathai, Vaishali Verma, Raghavendra Kamaraju, Alex Eapen

{"title":"Emerging Resistance in Anopheles stephensi Larvae to the Larvicide Temephos in Chennai, India.","authors":"Sangamithra Ravishankaran, Shalu Thomas, Aswin Asokan, Johnson Amala Justin Nalapatty Anthonysamy, Manu Thomas Mathai, Vaishali Verma, Raghavendra Kamaraju, Alex Eapen","doi":"10.4269/ajtmh.25-0232","DOIUrl":"10.4269/ajtmh.25-0232","url":null,"abstract":"This study aimed to evaluate the susceptibility of immature Anopheles stephensi to temephos formulation, a primary antilarval intervention currently in operational use. The assessment was conducted against both the WHO-recommended discriminatory dosage with temephos (0.25 parts per million [ppm]) and the operational field dosage with temephos 50% emulsifiable concentrate (EC; 1 ppm). F1 generation immature An. stephensi from two areas of Chennai, India was used for the study. The larvae (F1) from both areas were fully susceptible to the WHO discriminatory dosage. Larval susceptibility tests with temephos 50% EC observed 100% mortality in Thiruvanmiyur strains at 40 ppm (lethal concentration at which 99% of the exposed larvae were dead [LC99]: 37.47-45.06 ppm). However, Adyar strains exhibited 98.7% mortality at 50 ppm (LC99: 59.79 ppm). Anopheles stephensi larvae from both areas showed resistance to operational field dosage (1 ppm). Prolonged insecticide exposure precipitates resistance, highlighting the need for routine larvicide efficacy monitoring to support disease elimination efforts.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Intestinal Schistosomiasis with Concurrent Hepatic and Gastrointestinal Involvement Diagnosed by Computed Tomography. 计算机断层扫描诊断肝脏及胃肠道同时受累的肠道血吸虫病1例。

IF 1.6 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-08-14 DOI: 10.4269/ajtmh.25-0229

Seong-Jung Kim, Eun-Jeong Kim, Sung-Chul Lim, Da Hae Kwak, Dong-Min Kim

{"title":"A Case of Intestinal Schistosomiasis with Concurrent Hepatic and Gastrointestinal Involvement Diagnosed by Computed Tomography.","authors":"Seong-Jung Kim, Eun-Jeong Kim, Sung-Chul Lim, Da Hae Kwak, Dong-Min Kim","doi":"10.4269/ajtmh.25-0229","DOIUrl":"https://doi.org/10.4269/ajtmh.25-0229","url":null,"abstract":"Intestinal schistosomiasis is an uncommon disease that can present with a range of clinical symptoms and colonoscopic findings, depending on the affected organ, disease extent, and duration. Because these manifestations are not disease-specific, diagnosis can be difficult without clinical suspicion. In addition to fecal examinations to detect parasite eggs, computed tomography (CT) plays a crucial role in diagnosing intestinal schistosomiasis because it can reveal hallmark calcification patterns that are strongly suggestive of Schistosoma infection. A case of a 50-year-old Filipino female patient who presented with persistent abdominal pain is reported in the current study. She had experienced chronic abdominal pain for 10 years, which had acutely worsened over the past several days before presentation, accompanied by diarrhea. A previous colonoscopy performed at a local hospital revealed a 2 cm ulcer at the ileocecal valve. She was subsequently referred to the study institution for further evaluation of possible inflammatory bowel disease and other differential diagnoses. A CT scan performed before the colonoscopy revealed map-like hepatic calcifications and curvilinear calcifications in the bowel wall, suggestive of schistosomiasis. A subsequent colonoscopy with rectal biopsy and molecular analysis of paraffin-embedded tissue confirmed the presence of Schistosoma japonicum infection. The patient responded well to praziquantel.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144854265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rhabdomyolysis and Hepatitis Associated with Oropouche Fever: Brazil. 与Oropouche热相关的横纹肌溶解和肝炎：巴西。

IF 1.6 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-08-14 DOI: 10.4269/ajtmh.25-0107

Kalyne Gabrielle Caetano Ferreira, João Hugo Abdalla Santos, Geovana Ribeiro Pinheiro, Ligia Fernandes Abdalla, Lucas Carneiro Dos Santos

引用次数: 0

Workplace Violence and Associated Factors among Farmworkers in the Jabie-Tehnan District, Northwest Ethiopia: A Cross-Sectional Study. 埃塞俄比亚西北部Jabie-Tehnan地区农场工人的工作场所暴力及其相关因素：一项横断面研究。

IF 1.6 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-08-12 Print Date: 2025-10-01 DOI: 10.4269/ajtmh.24-0060

Assefa Mogess Birhanu, Dawit Getachew Yenealem, Eshetu Abera Worede, Bikes Destaw Bitew

{"title":"Workplace Violence and Associated Factors among Farmworkers in the Jabie-Tehnan District, Northwest Ethiopia: A Cross-Sectional Study.","authors":"Assefa Mogess Birhanu, Dawit Getachew Yenealem, Eshetu Abera Worede, Bikes Destaw Bitew","doi":"10.4269/ajtmh.24-0060","DOIUrl":"10.4269/ajtmh.24-0060","url":null,"abstract":"Millions of workers, particularly those in the agriculture sector, face workplace violence around the world. Workplace violence impacts on workers' psychosocial well-being, employment, job security, job satisfaction, rate of absenteeism, and productivity. The purpose of this study was to determine the prevalence of workplace violence and associated factors among farmworkers in west Gojjam, northwest Ethiopia. A total of 411 participants were recruited through stratified random sampling techniques in a cross-sectional study. Data were collected using pretested questionnaires based on face-to-face interviews. Bivariate and multivariable logistic regression analyses were performed to identify potential factors related to workplace violence. Adjusted odds ratio (AOR) with 95% CI of P-value <0.05 declared that the outcome was statistically significant. Workplace violence was experienced among 75.4% (95% CI: 71-80) of study participants. Employment in specific departments (AOR: 2.67, 95% CI: 1.36-5.21), employment in a labor administration department (AOR: 2.98, 95% CI: 1.01-8.7), employment in an agricultural department (AOR: 4.06, 95% CI: 1.29-12.7), status as a permanent employee (AOR: 3.0, 95% CI: 1.10-8.20), alcohol consumption (AOR: 6.4, 95% CI: 3.5-11.7), and khat chewing (AOR: 6.49, 95% CI: 2.88-14.6) were significantly associated with workplace violence. Farmworkers experienced a high rate of workplace violence. Workplace violence was found to be more common in the labor administration and agriculture departments as well as among permanent workers, alcohol drinkers, and khat chewers. Health education strategies are recommended to minimize the influence of unwanted workplace violence among farmworkers.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":"903-907"},"PeriodicalIF":1.6,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12493158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Anthropological Analysis of Acceptability and Feasibility of Expanding Community-Based Malaria Management to All Ages in Madagascar: Levers and Challenges for National Scale-Up. 在马达加斯加将社区疟疾管理扩展到所有年龄段的可接受性和可行性的人类学分析：国家规模的水平和挑战。

IF 1.6 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-08-12 DOI: 10.4269/ajtmh.24-0678

Hoby Fenitra Rabesandratra, Chiarella Mattern, Emilia Brazy-Nancy, Aina Harimanana, Judickaelle Irinantenaina, Hobisoa Léa Razanadranaivo, Pierrette Tianiaina Daniella Andrianambinintsoa, Catherine Dentinger, Laura Steinhardt, Andres Garchitorena

{"title":"An Anthropological Analysis of Acceptability and Feasibility of Expanding Community-Based Malaria Management to All Ages in Madagascar: Levers and Challenges for National Scale-Up.","authors":"Hoby Fenitra Rabesandratra, Chiarella Mattern, Emilia Brazy-Nancy, Aina Harimanana, Judickaelle Irinantenaina, Hobisoa Léa Razanadranaivo, Pierrette Tianiaina Daniella Andrianambinintsoa, Catherine Dentinger, Laura Steinhardt, Andres Garchitorena","doi":"10.4269/ajtmh.24-0678","DOIUrl":"10.4269/ajtmh.24-0678","url":null,"abstract":"Despite significant progress in reducing malaria effects in recent decades, malaria remains a major challenge in Madagascar. Geographic and financial barriers often prevent individuals from seeking prompt care. Community health workers (CHWs) in many countries, including Madagascar, provide malaria case management services to children younger than 5 years old, although they typically do not treat older children and adults, leaving a gap for those living far from health facilities. To determine the efficacy of expanding malaria community case management (mCCM) to community members of all ages, a cluster randomized trial was conducted in one district of Madagascar from November 2020 to December 2021. Qualitative surveys were conducted to describe the acceptability and feasibility of this intervention among beneficiaries and CHWs. For this purpose, 87 semistructured interviews and 12 focus groups were conducted in intervention and control arms of the study to assess understanding of malaria, behaviors related to care seeking for fever, perceptions of CHW roles, and acceptability and feasibility of the age-expanded mCCM. Two major findings emerged. First, stakeholders found age-expanded mCCM to be consistent with existing CHW roles and practices. Age-expanded mCCM induced a recognition of adults' susceptibility to malaria and led to a more accurate understanding of malaria. Second, structural and community-based challenges were not fully resolved by age-expanded mCCM, and some, such as the question of the cost of care, emerged after its implementation. Despite the fact that age-expanded mCCM was acceptable to beneficiaries and CHWs, successful scale-up will require addressing structural challenges and sociodemographic inequalities.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mumps Seroprevalence in Vellore, South India: A Community-Based Cross-Sectional Study. 流行性腮腺炎在印度南部Vellore的血清患病率：一项基于社区的横断面研究。

IF 1.6 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-08-12 Print Date: 2025-10-01 DOI: 10.4269/ajtmh.25-0069

Ramya Madhavan, Tintu Varghese, Akilandeswari Eswaran, Vaishnavi Gandhi, Poornima Saravanan, Lakshmi Raj, Reshma Raju, Julian Vivek Leander Xavier, Jovin Stanley Joseph, Prasanna Samuel Premkumar, Winsley Rose, Jacob John

{"title":"Mumps Seroprevalence in Vellore, South India: A Community-Based Cross-Sectional Study.","authors":"Ramya Madhavan, Tintu Varghese, Akilandeswari Eswaran, Vaishnavi Gandhi, Poornima Saravanan, Lakshmi Raj, Reshma Raju, Julian Vivek Leander Xavier, Jovin Stanley Joseph, Prasanna Samuel Premkumar, Winsley Rose, Jacob John","doi":"10.4269/ajtmh.25-0069","DOIUrl":"10.4269/ajtmh.25-0069","url":null,"abstract":"The mumps vaccine remains excluded from India's National Immunization Schedule (NIS) because of insufficient data on the community-level disease burden, despite mumps being a vaccine-preventable disease. In the present study, biobanked serum samples from an urban population in Vellore, stratified by age (in age groups of 1-5, 6-15, and 16-40 years) and sex, were tested for anti-mumps IgG antibodies using ELISA. The seroprevalence rates of mumps were 26%, 71%, and 84% in the 1- to 5-year, 6- to 15-year, and 16- to 40-year age groups, respectively, indicating a high burden in the community. Women in the 16- to 40-year age group exhibited a higher seroprevalence compared with males, with antibody levels consistently lower in males across both the 6- to 15-year and 16- to 40-year age groups (P <0.05). The present study highlights increasing mumps exposure with age and underscores the urgent need to include the mumps vaccine in the NIS to address the high disease burden and prevent complications.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":"883-887"},"PeriodicalIF":1.6,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12493236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Progressive Disseminated Histoplasmosis with Dermatomyositis and Macrophage Activation Syndrome/Hemophagocytic Lymphohistiocytosis. 进行性播散性组织胞浆菌病伴皮肌炎和巨噬细胞激活综合征/噬血细胞淋巴组织细胞病。

IF 1.6 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-08-12 Print Date: 2025-10-01 DOI: 10.4269/ajtmh.24-0802

Ashton D Hall, Divya Salibindla, Luis Dubocq-Cabrera, Madeline Hunt, Lea M Rotert, Rachel S Johnson, Anna R Balog, George S Deepe, Lisa A Haglund

{"title":"Progressive Disseminated Histoplasmosis with Dermatomyositis and Macrophage Activation Syndrome/Hemophagocytic Lymphohistiocytosis.","authors":"Ashton D Hall, Divya Salibindla, Luis Dubocq-Cabrera, Madeline Hunt, Lea M Rotert, Rachel S Johnson, Anna R Balog, George S Deepe, Lisa A Haglund","doi":"10.4269/ajtmh.24-0802","DOIUrl":"10.4269/ajtmh.24-0802","url":null,"abstract":"Histoplasmosis is the most common endemic mycosis in North and Central America, particularly in the Ohio and Mississippi River Valleys. Progressive disseminated histoplasmosis (PDH) occurs in ∼1 in 2,000 acute infections and may present atypically with multiorgan involvement, especially in immunocompromised hosts. We describe a case of PDH complicated by macrophage activation syndrome (MAS)/hemophagocytic lymphohistiocytosis (HLH) in a patient with dermatomyositis who was receiving long-term immunosuppressive therapy. She developed two uncommon manifestations of PDH: biopsy-proven cellulitis and intracellular yeasts within neutrophils on a peripheral blood smear. Diagnosis was delayed because of fungal antigen cross-reactivity and overlapping clinical and laboratory features of PDH and MAS/HLH. This case highlights the importance of early recognition, timely treatment, and coordinated multidisciplinary management. Our patient died 17 days after admission, underscoring the high mortality rate of MAS/HLH-associated histoplasmosis.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":"773-780"},"PeriodicalIF":1.6,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12493214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiology of and Risk Factors Associated with Mortality from Invasive Pulmonary Fungal Infection in Non-Neutropenic Patients in China: A 10-Year Retrospective Study. 中国非中性粒细胞减少患者侵袭性肺部真菌感染死亡率的流行病学及相关危险因素：一项10年回顾性研究

IF 1.6 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-08-12 Print Date: 2025-10-01 DOI: 10.4269/ajtmh.24-0463

Huimin Yang, Yukun Kuang, Ke-Jing Tang

{"title":"Epidemiology of and Risk Factors Associated with Mortality from Invasive Pulmonary Fungal Infection in Non-Neutropenic Patients in China: A 10-Year Retrospective Study.","authors":"Huimin Yang, Yukun Kuang, Ke-Jing Tang","doi":"10.4269/ajtmh.24-0463","DOIUrl":"10.4269/ajtmh.24-0463","url":null,"abstract":"The mortality rate associated with invasive pulmonary fungal infection (IPFI) is substantial, whereas epidemiological data pertaining to non-neutropenic patient cohorts is deficient. This study aims to analyze the epidemiology and identify risk factors associated with mortality from invasive pulmonary fungal infection in non-neutropenic populations. A retrospective study was conducted encompassing adult patients diagnosed with IPFI at the First Affiliated Hospital of Sun Yat-sen University between January 1, 2013, and December 31, 2022. A total of 513 patients were included in the study, and their survival information was retrospectively collected. A comparison of IPFI patient demographics between 2013-2017 and 2018-2022 revealed a marked elevation in the median age and a significant increase in the prevalence of comorbidities, including hypertension, hematological malignancies, and bronchiectasis. There was a notable shift in the prevalence of fungal pathogens, marked by an elevation in the proportion of individuals afflicted with Pneumocystis jirovecii. The 30-day mortality rate for IPFI patients remained relatively stable compared with the previous 5 years (11.71% versus 16.02%, P = 0.275). The Cox multivariate regression analysis revealed that intensive care unit admission (P <0.001), repeated blood transfusions (P = 0.042), and Aspergillus infection (P = 0.001) may be independent risk factors for all-cause mortality, respectively. A nomogram predicting 30-day all-cause mortality among patients with IPFI demonstrated satisfactory performance in terms of classification ability and calibration ability. These findings will contribute to better management of patients with IPFI by preventing the identified risk factors.","PeriodicalId":7752,"journal":{"name":"American Journal of Tropical Medicine and Hygiene","volume":" ","pages":"765-772"},"PeriodicalIF":1.6,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12493184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Gene Drive Research Losing Traction? 基因驱动研究正在失去吸引力？

IF 1.6 4区医学

American Journal of Tropical Medicine and Hygiene Pub Date : 2025-08-12 Print Date: 2025-10-01 DOI: 10.4269/ajtmh.25-0242

Gregory C Lanzaro, Ana M Kormos

引用次数: 0