左西孟旦静脉注射治疗严重蝎子中毒后急性心力衰竭伴肾功能损害:病例报告及文献回顾。

IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Karama Bouchaala, Mabrouk Bahloul, Amina Hadded, Oussama Haddar, Chokri Ben Hamida
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引用次数: 0

摘要

急性心力衰竭,表现为心源性休克或肺水肿,是世界上许多热带和亚热带地区蝎子中毒(SE)导致死亡的主要原因。标准的心力衰竭治疗,包括肌力药物和利尿剂治疗心源性休克和肺水肿,在大多数研究中使用。然而,据我们所知,左西孟旦在治疗SE后心源性休克并发肺水肿和肾损害中的作用很少有报道。在这里,我们报告了一例严重SE合并心源性休克和肺水肿的4岁患者,左西孟旦成功治疗。因此,在严重SE合并严重心源性休克的病例中,使用这种肌力药物似乎是有益的,而通常使用的肌力药物和血管加压剂(多巴酚丁胺和去甲肾上腺素)不能稳定这种情况。左西孟旦治疗严重SE所致心源性休克的有效性有待进一步研究证实。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Intravenous Levosimendan for Acute Heart Failure with Renal Impairment Following Severe Scorpion Envenomation: Case Report and Literature Review.

Acute heart failure, presenting as either cardiogenic shock or pulmonary edema, is the main cause of mortality because of scorpion envenomation (SE) in many tropical and subtropical parts of the world. Standard heart failure treatment, including inotropes and diuretics to treat cardiogenic shock and pulmonary edema, was used in most studies. However, the role of the inotrope levosimendan in the treatment of cardiogenic shock complicated by pulmonary edema and renal impairment after SE has rarely been reported, to the best of our knowledge. Here, we report this case of severe SE complicated by cardiogenic shock and pulmonary edema successfully managed with levosimendan in a 4-year-old patient. As a consequence, the use of this inotropic drug seems to be beneficial in severe cases of SE complicated by severe cardiogenic shock and not stabilized by the usually used inotropic and vasopressor agents (dobutamine and noradrenaline). Further studies are needed to confirm the usefulness of levosimendan in cardiogenic shock related to severe SE.

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来源期刊
American Journal of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生
CiteScore
6.20
自引率
3.00%
发文量
508
审稿时长
3 months
期刊介绍: The American Journal of Tropical Medicine and Hygiene, established in 1921, is published monthly by the American Society of Tropical Medicine and Hygiene. It is among the top-ranked tropical medicine journals in the world publishing original scientific articles and the latest science covering new research with an emphasis on population, clinical and laboratory science and the application of technology in the fields of tropical medicine, parasitology, immunology, infectious diseases, epidemiology, basic and molecular biology, virology and international medicine. The Journal publishes unsolicited peer-reviewed manuscripts, review articles, short reports, images in Clinical Tropical Medicine, case studies, reports on the efficacy of new drugs and methods of treatment, prevention and control methodologies,new testing methods and equipment, book reports and Letters to the Editor. Topics range from applied epidemiology in such relevant areas as AIDS to the molecular biology of vaccine development. The Journal is of interest to epidemiologists, parasitologists, virologists, clinicians, entomologists and public health officials who are concerned with health issues of the tropics, developing nations and emerging infectious diseases. Major granting institutions including philanthropic and governmental institutions active in the public health field, and medical and scientific libraries throughout the world purchase the Journal. Two or more supplements to the Journal on topics of special interest are published annually. These supplements represent comprehensive and multidisciplinary discussions of issues of concern to tropical disease specialists and health issues of developing countries
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