Aging Clinical and Experimental Research最新文献

{"title":"How does intergenerational support from adult children shape the intrinsic capacity of older adults? Empirical evidence from the CHARLS","authors":"Zhi Zeng,&nbsp;Guiqiong Xie,&nbsp;Yazhi He,&nbsp;Sumei Zhou","doi":"10.1007/s40520-025-03175-5","DOIUrl":"10.1007/s40520-025-03175-5","url":null,"abstract":"<div><h3>Background</h3><p>As China undergoes a rapid demographic shift toward population aging, a critical challenge has emerged for healthy aging policy: how can intergenerational support from adult children be leveraged to maintain and improve the functional ability of older adults? Drawing on nationally representative data, this study investigates the association between such support and the intrinsic capacity of older adults, and explores the pathways through which it operates.</p><h3>Methods</h3><p>This study utilizes data from the 2015, 2018, and 2020 waves of the China health and retirement longitudinal study (CHARLS). A multidimensional index of intergenerational support from adult children is constructed, incorporating financial support, emotional closeness, and caregiving. Two-way fixed effects models are employed to estimate the impact of such support on the intrinsic capacity of older adults. Furthermore, a mediation analysis is conducted—using the bootstrap method—to examine potential pathways through social participation, activities of daily living (ADL), and instrumental activities of daily living (IADL).</p><h3>Results</h3><p>The empirical findings indicate that all three forms of intergenerational support from adult children—financial, emotional, and caregiving—have significant positive effects on the intrinsic capacity of older adults, with caregiving showing the strongest impact. the effects vary across subgroups defined by urban–rural residence, educational attainment, and co-residence status, suggesting substantial heterogeneity. Mediation analysis reveals that social participation partially mediates the effect of financial support (accounting for 14.63% of the total effect), while ADL and IADL explain 60.28% and 53.90% of the effect of caregiving support, respectively.</p><h3>Conclusion</h3><p>intergenerational support from adult children significantly enhances the intrinsic capacity of older adults by promoting social engagement and maintaining functional ability. To advance healthy and active aging, policy efforts should adopt a function-oriented approach that strengthens both family-based support systems and community care infrastructure, while fostering cross-generational resource sharing and coordinated support</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"37 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40520-025-03175-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144920508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying latent classes of longitudinal change in picture naming in a population-based sample","authors":"Deborah Finkel,&nbsp;Ying Liu,&nbsp;Margaret Gatz,&nbsp;Stefan Schneider,&nbsp;Raymond Hernandez,&nbsp;Bart Orriens,&nbsp;Arie Kapteyn","doi":"10.1007/s40520-025-03169-3","DOIUrl":"10.1007/s40520-025-03169-3","url":null,"abstract":"<div><p>Although cognitive changes may not become apparent until after age 65, many factors associated with late-life decline are already well-established in midlife. In particular, deficits in picture naming have been associated with early and accelerated cognitive change. A measure of picture vocabulary, requiring participants to name drawings of objects, was collected in 4 waves (each separated by 2 years) of the Understanding America Study, a nationally representative internet panel (mean follow-up = 5.60 years). Participants were 5005 adults ranging in age from 18 to 98 at intake (mean = 48.81); 58% women. Growth mixture models were used to identify latent class structure in age-based quadratic growth models (centered at median age of 53). The best-fitting model identified 3 classes: high intercept and scores increase with age (60% of the sample), medium intercept and scores increase with age (37%), low intercept and no change with age (3%). Analyses of variance indicated that the class for which picture naming did not change with age had a significantly elevated probability of cognitive impairment. Multinomial logistic regression indicated that probability of cognitive impairment contributed to estimation of class membership even in the context of related demographic and cognitive variables. Tasks like Picture Vocabulary may be useful early indicators of onset of cognitive impairment.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"37 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40520-025-03169-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “Association between tooth loss and geriatric syndromes in older adults: a cohort study from a rural area in eastern China”","authors":"Efsun Somay","doi":"10.1007/s40520-025-03177-3","DOIUrl":"10.1007/s40520-025-03177-3","url":null,"abstract":"<div><p>I found the study by He et al. quite engaging, as it offers substantial longitudinal evidence linking dental health with various geriatric syndromes in a cohort of 1,094 individuals, specifically sarcopenia, malnutrition risk, frailty, and falls. The authors conducted rigorous clinical evaluations, including assessments of handgrip strength and body composition. They also utilized validated tools, such as the Mini Nutritional Assessment Short-Form (MNA-SF) and the FRAIL scale. The study's findings are significant: individuals with fewer than 10 teeth or those whose tooth loss has affected their daily activities demonstrated markedly increased odds of sarcopenia (OR 1.87–3.25), malnutrition risk (OR 2.31–3.64), and frailty. The absence of proper dentures significantly exacerbated these health risks, highlighting the importance of prosthetic rehabilitation, which, while beneficial, has its limitations in fully restoring oral function. This research strongly advocates for the prioritization of comprehensive oral health assessments and accessible denture provision as essential components of elderly care. The findings are particularly relevant to this rural cohort, emphasizing the need for targeted interventions in geriatric oral health, especially in resource-constrained environments where access to dental care might be limited. To further strengthen the study's relevance and scientific rigor, I propose several constructive recommendations that could enhance the research's overall impact.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"37 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40520-025-03177-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor- The association between sarcopenic obesity and depression in middle-aged and elderly U.S. adults: insights from the NHANES study","authors":"Jiang-yu Tu","doi":"10.1007/s40520-025-03079-4","DOIUrl":"10.1007/s40520-025-03079-4","url":null,"abstract":"<div><p>After reading “The association between sarcopenic obesity and depression in middle-aged and elderly U.S. adults: insights from the NHANES study”, we sincerely appreciate Zhang et al.‘s exploration of the relationship between sarcopenic obesity and depression in middle-aged and elderly populations, which provides new clinical perspectives for preventing sarcopenic obesity and depression. However, to more rigorously and clearly elucidate this relationship, several concerns must be addressed.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"37 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40520-025-03079-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regular glucosamine supplementation and risk of age-related chronic diseases: evidence from a propensity score-matched cohort study","authors":"Jing He,&nbsp;Yue Ma,&nbsp;Yan Jiang,&nbsp;Jianguang Ji,&nbsp;Fengju Song","doi":"10.1007/s40520-025-03171-9","DOIUrl":"10.1007/s40520-025-03171-9","url":null,"abstract":"<div><h3>Background</h3><p>Glucosamine is a widely used dietary supplement, particularly among middle-aged and older adults, with potential health benefits beyond joint health. However, its potential role in the prevention of chronic diseases remains uncertain.</p><h3>Aims</h3><p>To investigate the association between regular glucosamine use and the risk of age-related non-communicable diseases (NCDs) in a large prospective cohort.</p><h3>Methods</h3><p>269,033 participants in the large prospective cohort (UK Biobank) without NCDs at baseline were included. 1:1 propensity-score matching (PSM) was used to match glucosamine users with non-users. Cox proportional hazard regression was used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs).</p><h3>Results</h3><p>During a median follow-up of 13.8 years, 52,556 participants reported regular glucosamine use. After PSM, 52,525 users and 52,525 non-users were included in the matched cohort. After false discovery rate correction, regular glucosamine use was associated with a significantly lower risk of seven NCDs: esophageal cancer (HR, 0.73; 95% CI, 0.58–0.92), gout (HR, 0.81; 95% CI, 0.72–0.91), chronic obstructive pulmonary disease (HR, 0.86; 95% CI, 0.80–0.93), colorectal cancer (HR, 0.86; 95% CI, 0.78–0.94), chronic liver disease (HR, 0.87; 95% CI, 0.80–0.94), heart failure (HR, 0.88; 95% CI, 0.81–0.96), and coronary heart disease (HR, 0.92; 95% CI, 0.88–0.96).</p><h3>Conclusions</h3><p>Regular use of glucosamine was associated with a reduced risk of several age-related chronic diseases. Further studies are needed to confirm these findings and to clarify its potential role in supporting healthy aging.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"37 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40520-025-03171-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcopenia – the need for an Asian perspective","authors":"Jean Woo","doi":"10.1007/s40520-025-03174-6","DOIUrl":"10.1007/s40520-025-03174-6","url":null,"abstract":"<div><p>Sarcopenia research started in Asia about 25 years ago, and is now a rapidly developing field of research. The Asian Working Group in Sarcopenia was formed in 2014 with the publication of the first Consensus definition, followed and an update in 2019, with a most recent update in 2025. Cut off values used in the definition are different from those in Europe or the US, possibly due to a combination of social determinants of body composition and ethnicity. The importance of detection of sarcopenia in community and hospital settings is recognized; however a gap exists between research, public health and clinical practice in terms of case finding and management.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"37 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40520-025-03174-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the mediating role of telomere length in the association between physical activity and bone mineral density","authors":"Xiang Zhao,&nbsp;Yinhui Shi,&nbsp;Mengling Tang","doi":"10.1007/s40520-025-03176-4","DOIUrl":"10.1007/s40520-025-03176-4","url":null,"abstract":"<div><h3>Background</h3><p>Physical activity may mitigate osteoporosis progression by modulating telomere shortening processes.</p><h3>Aims</h3><p>To explore the mediating role of telomere length (TL) in the relationship between physical activity and bone mineral density (BMD).</p><h3>Methods</h3><p>This study enrolled 2,394 participants aged 50 years and older from the U.S. National Health and Nutrition examination Surveys. TL was measured by quantitative polymerase chain reaction (qPCR) method (TeloMean) and DNA methylation data (HorvathTelo), and accelerated telomere attrition was assessed through residual-based indices of TeloMeanAccel and HorvathTeloAccel. Physical activity was assessed via questionnaire and BMD was measured at multiple body sites. Multiple linear regression models were utilized to evaluate associations between TL metrics, physical activity, and BMD. Mediation analysis, restrict cubic spline (RCS) modeling, subgroup analyses and sensitivity analyses were further conducted.</p><h3>Results</h3><p>After adjusting for covariates, TL metrics of TeloMean and HorvathTelo were found significantly positive correlations with BMD. HorvathTeloAccel, reflecting accelerated telomere shortening, also exhibited significant association with BMD. Physical activity demonstrated a significant positive association with total BMD (β = 0.046, 95%CI: 0.004–0.088). Mediation analysis revealed that TeloMean and HorvathTelo accounted for 4.78% and 20.86% of the total effect of physical activity on BMD, respectively, while HorvathTeloAccel explained 5.24% of the observed association.</p><h3>Conclusion</h3><p>Reduced physical activity and accelerated telomere attrition were related with BMD decline, and TL partially mediated the association. These findings suggest that enhancing physical activity could mitigate telomere shortening and promote bone health.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"37 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40520-025-03176-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between preoperative blood–brain barrier permeability and postoperative delirium in older patients undergoing cardiac surgery: a pilot study","authors":"Lichao Di,&nbsp;Peiying Huang,&nbsp;Yeju He,&nbsp;Jie Li,&nbsp;Yu Liu,&nbsp;Liwei Chi,&nbsp;Na Sun,&nbsp;Lining Huang","doi":"10.1007/s40520-025-03140-2","DOIUrl":"10.1007/s40520-025-03140-2","url":null,"abstract":"<div><h3>Background</h3><p>Postoperative delirium (POD) is a frequent and serious complication in older adults after cardiac surgery. Blood–brain barrier (BBB) dysfunction is implicated in cognitive decline, but its preoperative role in POD remains underexplored. This pilot study aimed to investigate the association between preoperative regional BBB permeability, assessed by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), and POD in older patients undergoing off-pump coronary artery bypass grafting (OPCABG). </p><h3>Methods</h3><p>This prospective observational pilot study, registered in the Chinese Clinical Trial Registry (ChiCTR2200063774), included patients aged ≥ 65 years scheduled for OPCABG. Preoperative BBB permeability (quantified as Ktrans) in the hippocampus, thalamus, frontal lobe, and temporal lobe, along with regional brain volumes and Montreal Cognitive Assessment-Basic (MoCA-B) scores, were assessed. POD was diagnosed using the 3-Minute Diagnostic Confusion Assessment Method (3D-CAM) or CAM-ICU for 5 postoperative days. Univariable and multivariable logistic regression analyses were performed to identify predictors of POD. Correlations between Ktrans, volume, and POD severity (CAM-S) were examined.</p><h3>Results</h3><p>Fifty patients (mean age 69.0 ± 3.3 years) were analyzed; 19 (38%) developed POD. In univariable analysis, higher preoperative Ktrans in the hippocampus (Odds Ratio [OR] 1.350, 95%CI 1.048–1.740, <i>P</i> = 0.020) and thalamus (OR 1.466, 95%CI 1.017–2.113, <i>P</i> = 0.040), lower MoCA-B scores (P = 0.020), and smaller hippocampal (OR 0.297, 95%CI 0.131–0.672, <i>P</i> = 0.004) and thalamic volumes (OR 0.304, 95%CI 0.121–0.766, <i>P</i> = 0.012) were associated with POD. However, in multivariable logistic regression including MoCA-B, Ktrans, and volumes, only lower MoCA-B scores (OR 0.697, 95%CI 0.513–0.947, <i>P</i> = 0.021) and smaller hippocampal volume (OR 0.322, 95%CI 0.105–0.992, P = 0.048) remained independent predictors of POD incidence. Preoperative hippocampal Ktrans correlated significantly with POD severity (CAM-S, r = 0.673, <i>P</i> = 0.002).</p><h3>Conclusion</h3><p>In this pilot study, while increased preoperative BBB permeability in the hippocampus and thalamus was associated with POD univariably, baseline cognitive function and hippocampal volume were stronger independent preoperative predictors of POD incidence after OPCABG. Higher preoperative hippocampal BBB permeability was associated with greater POD severity, suggesting a role for pre-existing BBB vulnerability in exacerbating delirium. These preliminary and exploratory findings warrant validation in larger, adequately powered cohorts and highlight the complex interplay of pre-existing brain vulnerabilities in POD development.</p><h3>Trial registration</h3><p>Chinese Clinical Trial Registry (ChiCTR2200063774; registered on 09/16/2022).</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"37 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40520-025-03140-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anticholinergic medication use and falls in Australian residential aged care: a retrospective multisite cohort study","authors":"Ying Xu,&nbsp;Magdalena Z. Raban,&nbsp;Ling Li,&nbsp;Amy D. Nguyen,&nbsp;S. Sandun Malpriya Silva,&nbsp;Guogui Huang,&nbsp;Gaston Arnolda,&nbsp;Johanna I. Westbrook,&nbsp;Nasir Wabe","doi":"10.1007/s40520-025-03147-9","DOIUrl":"10.1007/s40520-025-03147-9","url":null,"abstract":"<div><h3>Background</h3><p>Associations between anticholinergic load and falls remain understudied in residential aged care facilities (RACFs).</p><h3>Aims</h3><p>To examine associations between anticholinergic load and falls in the first year after entry to an RACF.</p><h3>Methods</h3><p>We aggregated routinely collected data from 27 RACFs in New South Wales, Australia. Anticholinergic load and falls were repeatedly measured for one year after residents first entered an RACF. Thirteen 28-day review periods were set. Associations between anticholinergic load in a review period and any falls in the next review period were examined, comprising 12 repeated measurements of associations. We included new residents aged ≥ 65 years, who entered an RACF between 1 July 2014 and 2 September 2021. Six scales were used: Anticholinergic Cognitive Burden (ACB), Anticholinergic Drug Scale (ADS), Anticholinergic Loading Scale (ALS), Anticholinergic Risk Scale (ARS), Chew’s list, and Clinician-rated Anticholinergic Score (CrAS). We used mixed-effect logistic regression models, adjusting for potential confounders. Facility was used as a cluster variable.</p><h3>Results</h3><p>For the 2300 residents (67.7% females), there were steady increases in mean anticholinergic load from the first to the 12th review period. Per one-point higher anticholinergic load was associated with an increased risk of falls, adjusted odds ratios: 1.08 (95% confidence interval[CI] 1.04, 1.12) using ACB, 1.11 (95%CI 1.06, 1.15) using ADS, 1.15 (95%CI 1.10, 1.21) using ALS, 1.10 (95%CI 1.04, 1.17) using ARS, 1.18 (95%CI 1.09, 1.27) using Chew’s list, and 1.14 (95%CI 1.10, 1.19) using CrAS.</p><h3>Conclusion</h3><p>Anticholinergic scales may be useful to inform falls prevention programs for new RACF residents.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"37 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40520-025-03147-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Towards a better understanding of patient expectations: ONCOPREMs-1 study—a qualitative study","authors":"Loubna Diouri,&nbsp;Fiona Ecarnot,&nbsp;Sophie Berjot,&nbsp;Alexandre Popiolek,&nbsp;Olivier Bouché,&nbsp;Damien Botsen,&nbsp;Amélie Lemoine,&nbsp;Stéphane Vignot,&nbsp;Coralie Barbe","doi":"10.1007/s40520-025-03148-8","DOIUrl":"10.1007/s40520-025-03148-8","url":null,"abstract":"<div><h3>Introduction</h3><p>As part of a broader study entitled OncoPREMs, which aims to develop a tool to assess patients’ experiences throughout their oncology care pathway, we explored patients’ perceptions and expectations from the first signs of illness to the post-cancer phase, as well as their experience of living with cancer.</p><h3>Methods</h3><p>A qualitative study was conducted using semi-structured interviews with patients who had been treated or were undergoing treatment for cancer in various healthcare facilities in France. Patients were recruited by healthcare professionals at their care sites.</p><h3>Results</h3><p>A total of 28 interviews were conducted between May and August 2023 (14 men, 14 women). The most common types of cancer were breast, digestive, and urological cancers. Thematic analysis identified several key themes related to the patient experience: the period of disease discovery and diagnosis; treatment follow-up and management of side effects; and the post-cancer phase or “living with cancer.”</p><h3>Conclusion</h3><p>The results of this study show that the different stages of the care pathway generally meet the expectations and needs of patients treated for cancer. However, patients expressed hopes for further developments, such as more support and guidance for their caregivers from healthcare professionals.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"37 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40520-025-03148-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144896946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}