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Rare Case of Twin Reversed Arterial Perfusion Acardius Acephalus Subtype Seen in a Community-Based Hospital. 社区医院中出现的罕见双子动脉灌注逆转心绞痛亚型病例
IF 0.8
AJP Reports Pub Date : 2024-09-10 eCollection Date: 2024-07-01 DOI: 10.1055/a-2384-8058
Laura Reguero Cadilla, Carlos Villafuerte Santana, Nicolle Centazzo, Daniel Faustin
{"title":"Rare Case of Twin Reversed Arterial Perfusion <i>Acardius Acephalus</i> Subtype Seen in a Community-Based Hospital.","authors":"Laura Reguero Cadilla, Carlos Villafuerte Santana, Nicolle Centazzo, Daniel Faustin","doi":"10.1055/a-2384-8058","DOIUrl":"https://doi.org/10.1055/a-2384-8058","url":null,"abstract":"<p><p><b>Background</b>  TRAP sequence occurs in monochorionic pregnancies consisting of one normal fetus and a non-viable fetus. The pump twin has an increased risk of developing high-output cardiac failure. <b>Case</b>  32-year-old G4P2012 with TRAP syndrome in current pregnancy presented to triage at 26 weeks with contractions and spotting. She had undergone RFA for selective reduction at another facility. Placental abruption was suspected and patient underwent a cesarean section. Twin A was delivered alive although she subsequently succumbed due to complications of prematurity. <b>Conclusion</b>  This case highlights the importance of early detection and consistent prenatal care in the management of TRAP sequence. Further research of interventions associated with improved outcomes should be encouraged.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 3","pages":"e224-e227"},"PeriodicalIF":0.8,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11387039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predeposit Autologous Blood Donation in Rh(D)-Negative Pregnant Women: A Single-Center Study. Rh(D)阴性孕妇的预置自体血捐献:单中心研究。
IF 0.8
AJP Reports Pub Date : 2024-08-30 eCollection Date: 2024-07-01 DOI: 10.1055/a-2388-3298
Juan Xie, Yu Ling, Xiaoyu Zhou
{"title":"Predeposit Autologous Blood Donation in Rh(D)-Negative Pregnant Women: A Single-Center Study.","authors":"Juan Xie, Yu Ling, Xiaoyu Zhou","doi":"10.1055/a-2388-3298","DOIUrl":"10.1055/a-2388-3298","url":null,"abstract":"<p><p><b>Objective</b>  The primary purpose of this study was to assess the practicability of predeposit autologous blood donation (PABD) in the practice of Rh(D)-negative pregnant women. <b>Materials and Methods</b>  A cohort of 405 Rh(D)-negative pregnant women who had a delivery in the comprehensive tertiary hospital in Nanjing was analyzed retrospectively, over 10 years. <b>Results</b>  After PABD, 203 women experienced a slight drop in mean hemoglobin of 5.32 ± 0.5 g/L (PABD-associated anemia was not featured in our study). Thirteen women who received allogeneic blood might benefit from PABD practically. <b>Conclusion</b>  PABD is applicable for Rh(D)-negative pregnant women, as it ensures the availability of the patient's blood in the event of perinatal hemorrhage, thus minimizing the need for transfusion from external sources. Despite the autologous blood reinfusion of low proportion, PABD could still serve as an alternative when allogeneic blood resources are scarce. However, one challenge in the future is to identify candidates who may benefit most from PABD. Also, more attention is needed to raise awareness of patient blood management. Recommended strategies include early screening and treatment of anemia, hemostasis promotion, and blood loss reduction. Replacement of allogeneic transfusion with autotransfusion could be referred to where feasible. We believe that PABD still has a promising potential for application in Rh(D)-negative pregnant women.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 3","pages":"e208-e214"},"PeriodicalIF":0.8,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11364468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Vein of Galen Aneurysmal Malformation Diagnosed Prenatally in a Monochorionic-Diamniotic Twin Pregnancy. 一例单绒毛膜双羊膜妊娠产前诊断为盖伦静脉动脉瘤畸形的病例
IF 0.8
AJP Reports Pub Date : 2024-08-29 eCollection Date: 2024-07-01 DOI: 10.1055/a-2385-1263
Dana Senderoff Berger, Andre Robinson, Judith Chervenak, Kristen Thomas, Ranjini Srinivasan, Geeta Sharma, Ashley S Roman, Christina A Penfield, Meghana Limaye
{"title":"A Case of Vein of Galen Aneurysmal Malformation Diagnosed Prenatally in a Monochorionic-Diamniotic Twin Pregnancy.","authors":"Dana Senderoff Berger, Andre Robinson, Judith Chervenak, Kristen Thomas, Ranjini Srinivasan, Geeta Sharma, Ashley S Roman, Christina A Penfield, Meghana Limaye","doi":"10.1055/a-2385-1263","DOIUrl":"10.1055/a-2385-1263","url":null,"abstract":"<p><p>We present a case of a vein of Galen aneurysmal malformation (VGAM), a rare congenital arteriovenous malformation, in one fetus of a monochorionic-diamniotic twin pregnancy. The diagnosis was made with color Doppler ultrasonography at 28 weeks and the affected fetus was found to have worsening cardiomegaly on subsequent fetal echocardiograms. She was emergently delivered at 32 weeks for abnormal fetal heart rate tracing of the affected twin. Magnetic resonance imaging of the brain findings after delivery demonstrated severe neurological injury; therefore, postnatal embolization was not performed. The neonate died on day of life 9. The cotwin survived without neurological complications. This is the first case in the literature of a VGAM diagnosed prenatally in a monochorionic-diamniotic twin pregnancy and demonstrates the challenge of delivery timing with prenatal diagnosis in a twin pregnancy.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 3","pages":"e202-e204"},"PeriodicalIF":0.8,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11361778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital Umbilical Cord Hernia: Prenatal and Postnatal Management. 先天性脐带疝:产前和产后管理。
IF 0.8
AJP Reports Pub Date : 2024-08-29 eCollection Date: 2024-07-01 DOI: 10.1055/s-0044-1790207
Stephanie Rodriguez, Daisy Marty, Barbara Folga, Layan Alrahmani
{"title":"Congenital Umbilical Cord Hernia: Prenatal and Postnatal Management.","authors":"Stephanie Rodriguez, Daisy Marty, Barbara Folga, Layan Alrahmani","doi":"10.1055/s-0044-1790207","DOIUrl":"10.1055/s-0044-1790207","url":null,"abstract":"<p><p>Congenital umbilical cord hernia is often misdiagnosed and easily confused with a small omphalocele. It is different from postnatally diagnosed umbilical hernias and is believed to arise from persistent physiological mid-gut herniation. Its incidence is estimated to be 1 in 5,000, although some articles reported the incidence rate of approximately 0.2%. It is very important to clearly diagnose these cases in the antenatal period so that the patients receive appropriate management postnatally and to decrease the stress in the parents as well. Umbilical cord hernias have not been associated with other chromosomal anomalies. In this article, we describe a case of a patient who was diagnosed with an umbilical cord mass for which the course prenatally and postnatally was uncomplicated. It is very important to avoid misdiagnosing these cases, so that patients are appropriately treated in the postnatal course and to prevent complications such as bowel injury during cord clamping.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 3","pages":"e205-e207"},"PeriodicalIF":0.8,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11361777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preterm Infant's Heart Rate Variability Near Birth Predicts Autonomic Symptoms at Age 3 to 5 Years. 早产儿出生时的心率变异性可预测其 3-5 岁时的自主神经症状。
IF 0.8
AJP Reports Pub Date : 2024-07-29 eCollection Date: 2024-07-01 DOI: 10.1055/s-0044-1788700
Noa Zohar, Michal Katz-Leurer, Luba Zuk, Hadas Israeli-Mendlovic
{"title":"Preterm Infant's Heart Rate Variability Near Birth Predicts Autonomic Symptoms at Age 3 to 5 Years.","authors":"Noa Zohar, Michal Katz-Leurer, Luba Zuk, Hadas Israeli-Mendlovic","doi":"10.1055/s-0044-1788700","DOIUrl":"10.1055/s-0044-1788700","url":null,"abstract":"<p><p><b>Aims</b>  To describe the autonomic function of premature infants born between 28 and 32 weeks of gestation, without medical risk factors, at the age of 3 to 5 years and to assess whether it's possible to predict the appearance of autonomic deficits in these children at this age range. <b>Methods</b>  This follow-up study included 40 out of 55 premature infants born between weeks 28 and 32 during 2018 to 2020. During 2022 to 2023 parents were asked to report on medical and developmental follow-up and treatment, functional characteristics of the autonomic system, and the age at which walking was achieved. <b>Results</b>  Approximately 27% of the participants (11 out of 40) presented autonomic symptoms at 3 to 5 years of age. A predictive relationship was noted between the function of the heart rate control system near birth and the presence of autonomic dysfunctions at ages 3 to 5. Fourteen of 40 children received neurodevelopmental treatments. However, children with autonomic symptoms were not treated for their symptoms. <b>Conclusion</b>  These preliminary findings provide valuable insights into the autonomic function of children born premature and the potential predictive relationship between early autonomic measures and later autonomic dysfunctions. It also highlights the need for increased awareness and intervention strategies for addressing autonomic issues in premature infants to support their overall well-being.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 3","pages":"e197-e201"},"PeriodicalIF":0.8,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11286323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141854504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prenatal Diagnosis of a Right Atrial Appendage Aneurysm: Case Report and Review of the Literature. 右心房阑尾动脉瘤的产前诊断:病例报告和文献综述。
IF 0.9
AJP Reports Pub Date : 2024-06-04 eCollection Date: 2024-04-01 DOI: 10.1055/s-0044-1787066
Jezid Miranda, Dulce María Villalobo, Nikita Alfieri, Brenda Contreras, Gabriel Vergara
{"title":"Prenatal Diagnosis of a Right Atrial Appendage Aneurysm: Case Report and Review of the Literature.","authors":"Jezid Miranda, Dulce María Villalobo, Nikita Alfieri, Brenda Contreras, Gabriel Vergara","doi":"10.1055/s-0044-1787066","DOIUrl":"10.1055/s-0044-1787066","url":null,"abstract":"<p><p><b>Introduction</b>  Congenital malformations of the right atrium are rare heart defects with only a few cases described prenatally. Early diagnosis of these anomalies is becoming increasingly important for proper follow-up and due to the possibility of serious complications such as supraventricular arrhythmia, thromboembolic events, and sudden death. <b>Objective</b>  The atrial appendage aneurysm (AAA) is a dilatation of the atrial appendage. It is considered an extremely rare congenital anomaly. However, this condition is clinically significant because it leads to atrial arrhythmias, recurrent emboli, heart failure, and chest pain. In addition, it is possible to recognize AAA prenatally with fetal echocardiography, even if it rarely happens. However, few fetal AAA cases have been reported in the literature. <b>Study Design</b>  We report a case of a fetal AAA; diagnosed prenatally and with postnatal confirmation. We undertook a systematic review of studies on fetal AAA to synthesize available knowledge on diagnosing and managing this rare condition. <b>Results</b>  A total of eight studies describing 24 patients were identified and analyzed. <b>Conclusion</b>  Despite their rarity, fetal atrial appendage aneurysms necessitate early detect on due to associated severe complications. Our findings emphasize the importance of prenatal diagnosis through fetal echocardiography and highlight the need for further research to optimize management strategies and improve outcomes for affected individuals.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 2","pages":"e170-e176"},"PeriodicalIF":0.9,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11150053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed-Interval Delivery in Multiple Pregnancy: A Single-Center Experience of Five Cases. 多胎妊娠的延迟临产:五例单中心经验
IF 0.9
AJP Reports Pub Date : 2024-05-23 eCollection Date: 2024-04-01 DOI: 10.1055/s-0044-1787112
Roaa Hassan Gadeer, Ahlam Alhinai, Karen Fung-Kee-Fung, Ana Werlang
{"title":"Delayed-Interval Delivery in Multiple Pregnancy: A Single-Center Experience of Five Cases.","authors":"Roaa Hassan Gadeer, Ahlam Alhinai, Karen Fung-Kee-Fung, Ana Werlang","doi":"10.1055/s-0044-1787112","DOIUrl":"10.1055/s-0044-1787112","url":null,"abstract":"<p><p><b>Objectives</b>  To describe the obstetric management and perinatal outcomes in multiple pregnancies with delayed-interval delivery (DID) of the cotwin in a tertiary hospital. <b>Methods</b>  This is a retrospective chart review of all cases of DID between December 2021 and 2022 at The Ottawa Hospital. Five cases of DID were identified and reviewed to obtain information on obstetric management and maternal-neonatal outcomes. We included eligible twins and triplets. No multiples were excluded. We obtained ethics approval for this case series. <b>Results</b>  Four sets of dichorionic diamniotic twins and one trichorionic triamniotic triplet were included. Our patients were admitted between 17 <sup>3/7</sup> and 21 <sup>5/7</sup> weeks of gestation. We achieved an interval delivery range between 1 and 36 days. Four out of six multiples did not survive in DID. The two surviving newborns were born at 23 <sup>0/7</sup> and 23 <sup>2/7</sup> , stayed in the neonatal intensive care unit (NICU) for 111 and 131 days, discharged with a weight of 3,594 and 2,743 g, respectively. All DID cases were delivered spontaneously except for two patients that required augmentation due to maternal sepsis. <b>Conclusion</b>  Despite the high risk of maternal, fetal, and neonatal morbidity and mortality, if delivery of the first twin occurs before 20 gestational weeks, DID could be considered in selected cases to improve outcomes for the cotwin.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 2","pages":"e156-e161"},"PeriodicalIF":0.9,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11115972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141086648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Type III Vasa Previa Associated with Resolution of a Low-Lying Placenta: Case Report and Literature Review. 与低置胎盘剥离有关的 III 型前置胎盘:病例报告和文献综述
IF 0.9
AJP Reports Pub Date : 2024-05-10 eCollection Date: 2024-04-01 DOI: 10.1055/a-2315-7550
Joanna J Kim, Katherine Bonhomme, Lawrence W Oppenheimer, Laura Gaudet
{"title":"Type III Vasa Previa Associated with Resolution of a Low-Lying Placenta: Case Report and Literature Review.","authors":"Joanna J Kim, Katherine Bonhomme, Lawrence W Oppenheimer, Laura Gaudet","doi":"10.1055/a-2315-7550","DOIUrl":"10.1055/a-2315-7550","url":null,"abstract":"<p><p>Vasa previa occurs when fetal vessels lie above the cervical os. A novel type of vasa previa, known as type III, is characterized by an abnormal branching of fetal vessels from the placenta in the absence of velamentous cord insertion (as seen in type I) or multilobed placenta (as seen in type II). Here, we present a case of a type III vasa previa after a resolution of a low-lying placenta. The presence of any known risk factors of vasa previa, including low-lying placenta, should prompt screening for vasa previa in the third trimester. Accurate and timely diagnosis of vasa previa will confer significant survival benefit for the neonate.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 2","pages":"e136-e139"},"PeriodicalIF":0.9,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11087141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140910852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Percutaneous Drainage for Giant Pulmonary Interstitial Emphysema in a Tiny Infant with a Birth Weight of 327 g. 经皮引流治疗出生体重 327 克的小婴儿的巨大肺间质气肿
IF 0.9
AJP Reports Pub Date : 2024-05-03 eCollection Date: 2024-04-01 DOI: 10.1055/s-0044-1786713
Yuta Hoshina, Ryo Ogawa, Arata Oda, Yoshiya Kamei, Tomohiko Nakamura
{"title":"Percutaneous Drainage for Giant Pulmonary Interstitial Emphysema in a Tiny Infant with a Birth Weight of 327 g.","authors":"Yuta Hoshina, Ryo Ogawa, Arata Oda, Yoshiya Kamei, Tomohiko Nakamura","doi":"10.1055/s-0044-1786713","DOIUrl":"https://doi.org/10.1055/s-0044-1786713","url":null,"abstract":"<p><p>Giant pulmonary cyst in extremely low birth weight (ELBW) infants has been described as one of severe pulmonary diseases. Any definitive therapy for refractory cases, where conservative methods of treatments are not effective, has not been established as a standard. Herein, we report an ELBW infant with a giant pulmonary cyst cured by percutaneous drainage without any adverse events. A female infant was born with a birth weight of 327 g. Surfactant was administered on days 1 and 2 of life to treat respiratory distress syndrome. Tracheal intubation was performed and synchronized intermittent mandatory ventilation was promptly initiated following birth. On the course, right giant pulmonary cyst developed on day 9 after birth. Although we started conservative therapy, including right lateral decubitus positioning, high-frequency oscillatory ventilation, and systemic corticosteroid administration, the diameter of the cyst had reached 34 mm, and mediastinal displacement was observed on day 28 after birth when she weighed 393 g. She recovered by percutaneous drainage followed by suction with a pressure of -10 cm H <sub>2</sub> O under mild sedation for 3 days. We believe that percutaneous drainage can be one of the available options for unilateral pulmonary interstitial emphysema.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 2","pages":"e133-e135"},"PeriodicalIF":0.9,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11068432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140847444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-Titer Type O Whole Blood for Transfusing Perinatal Patients after Acute Hemorrhage: A Case Series. 低滴度 O 型全血用于急性出血后围产期患者的输血:病例系列。
IF 0.9
AJP Reports Pub Date : 2024-05-03 eCollection Date: 2024-04-01 DOI: 10.1055/s-0044-1786712
Nicholas R Carr, Timothy M Bahr, Robin K Ohls, Sarah M Tweddell, David S Morris, Terry Rees, Sarah J Ilstrup, Walter E Kelley, Robert D Christensen
{"title":"Low-Titer Type O Whole Blood for Transfusing Perinatal Patients after Acute Hemorrhage: A Case Series.","authors":"Nicholas R Carr, Timothy M Bahr, Robin K Ohls, Sarah M Tweddell, David S Morris, Terry Rees, Sarah J Ilstrup, Walter E Kelley, Robert D Christensen","doi":"10.1055/s-0044-1786712","DOIUrl":"https://doi.org/10.1055/s-0044-1786712","url":null,"abstract":"<p><p><b>Objective</b>  Acute and massive blood loss is fortunately a rare occurrence in perinatal/neonatal practice. When it occurs, typical transfusion paradigms utilize sequential administration of blood components. However, an alternative approach, transfusing type O whole blood with low anti-A and anti-B titers, (LTOWB) has recently been approved and utilized in trauma surgery. <b>Study Design</b>  Retrospective analysis of all perinatal patients who have received LTOWB after acute massive hemorrhage at the Intermountain Medical Center. <b>Results</b>  LTOWB was the initial transfusion product we used to resuscitate/treat 25 women with acute and massive postpartum hemorrhage and five infants with acute hemorrhage in the first hours/days after birth. We encountered no problems obtaining or transfusing this product and we recognized no adverse effects of this treatment. <b>Conclusion</b>  Transfusing LTOWB to perinatal patients after acute blood loss is feasible and appears at least as safe a serial component transfusion. Its use has subsequently been expanded to multiple hospitals in our region as first-line transfusion treatment for acute perinatal hemorrhage. <b>Key Points</b> Low-titer type O whole blood (LTOWB) was our initial transfusion product for 30 perinatal patients with acute hemorrhage. Twenty-five of these were obstetrical patients and five were neonatal patients. We encountered no problems with, or adverse effects from LTOWB in any of these patients. LTOWB transfusions to women were ten days since donor draw (interquartile range, 8-13) and to neonates was six days (5-8).</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 2","pages":"e129-e132"},"PeriodicalIF":0.9,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11068431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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