AJP Reports最新文献_第3页

Infant with Known Dandy-Walker Malformation and Poor Feeding Found to Have Additional Diagnosis. 婴儿有已知的丹迪步行者畸形和喂养不良被发现有额外的诊断。

IF 0.8

AJP Reports Pub Date : 2025-04-08 eCollection Date: 2025-04-01 DOI: 10.1055/a-2562-1814

Jacob Q Lin, April Cooke, Nick Townley

引用次数: 0

Adverse Pregnancy Outcomes in Sjogren's Disease Compared to Controls: An Interdisciplinary Approach with Maternal-Fetal Medicine. 与对照组相比，干燥病的不良妊娠结局：母胎医学的跨学科方法。

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AJP Reports Pub Date : 2025-04-08 eCollection Date: 2025-04-01 DOI: 10.1055/a-2562-1643

Lauren Tesoriero, Jennifer Kidd, Julie Piccione, Peter Izmirly, Meredith Akerman, Steven Carsons, Patricia Rekawek, Julie Nusbaum

{"title":"Adverse Pregnancy Outcomes in Sjogren's Disease Compared to Controls: An Interdisciplinary Approach with Maternal-Fetal Medicine.","authors":"Lauren Tesoriero, Jennifer Kidd, Julie Piccione, Peter Izmirly, Meredith Akerman, Steven Carsons, Patricia Rekawek, Julie Nusbaum","doi":"10.1055/a-2562-1643","DOIUrl":"https://doi.org/10.1055/a-2562-1643","url":null,"abstract":"Objectives: Outside of the association of SS-A antibody with congenital heart block, little is known about adverse maternal and neonatal outcomes, in patients with Sjogren's disease (SjD). Our study involved collaboration with maternal-fetal medicine (MFM).Methods: A retrospective cohort study of pregnant patients: SjD patients were matched 1:3 with non-SjD controls. SjD patients were included by meeting the 2016 ACR/EULAR Criteria or by a rheumatologist diagnosis. Exclusion criteria were concurrent autoimmune disease or related antibodies. A composite of grouped outcomes was utilized and verified by MFM specialists. The primary outcome was adverse pregnancy outcome (APO) between the two groups. Statistical analysis was performed using a two-sample t -test and Fisher's exact test.Results: 48 patients were included: 12 SjD patients and 36 controls. APO was significantly increased in SjD with one preterm birth, one fetal growth restriction, and one limb anomaly; non-SjD had one cardiac anomaly. There were no cases of CHB. SjD patients were more likely to be delivered by cesarean delivery.Conclusion: There was an increased risk of APO in SjD patients compared with controls. No significant difference in neonatal outcomes was found. We speculate that placental pathology may play a role in pathophysiology and future studies should be performed.Key points: There was an increased risk of APO in SjD patients compared with controls.No significant difference in neonatal outcomes was found.We speculate that placental pathology may play a role in pathophysiology, prompting future studies.","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"15 2","pages":"e47-e52"},"PeriodicalIF":0.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal PlGF and sFlt-1 are Associated with Low Birth Weight and/or Small-for-Gestational Age Neonates in Pregnancy with or without Preeclampsia. 孕妇PlGF和sFlt-1与伴有或不伴有子痫前期的低出生体重和/或小胎龄新生儿相关

IF 0.8

AJP Reports Pub Date : 2025-03-31 eCollection Date: 2025-01-01 DOI: 10.1055/a-2555-1742

Wenbo Luo, Pingping Tang, Yan Lv, Yijun Song, Huiying Hu, Jinsong Gao, Juntao Liu

{"title":"Maternal PlGF and sFlt-1 are Associated with Low Birth Weight and/or Small-for-Gestational Age Neonates in Pregnancy with or without Preeclampsia.","authors":"Wenbo Luo, Pingping Tang, Yan Lv, Yijun Song, Huiying Hu, Jinsong Gao, Juntao Liu","doi":"10.1055/a-2555-1742","DOIUrl":"10.1055/a-2555-1742","url":null,"abstract":"Objective: To evaluate the association of PIGF and sFlt-1 with low birth weight and/or small-for-gestational age neonates in pregnancy with or without preeclampsia.Methods: Singleton pregnancies with sFlt-1/PlGF tested were included and set into four groups for case-control analysis. Distribution of sFlt-1/PlGF, sFlt-1, PlGF, and PGF% were evaluated, Kruskal-Wallis test and Mann-Whitney U test were adopted for significance analysis.Results: Maternal sFlt-1/PlGF, PlGF, PlGF%, and sFlt-1 were statistically associated with low birth weight and/or small-for-gestational age in pregnancy complicated or uncomplicated with preeclampsia. A significant difference was shown on sFlt-1/PIGF ( p = 0.0082), PIGF% ( p = 0.0326), PIGF ( p = 0.0128), and sFlt-1 ( p = 0.0469) in pregnancy with small-for-gestational age and/or low birth weight neonates. A significantly higher median of sFlt-1/PlGF (448 vs. 61.6, p < 0.0001) and sFlt-1 (15499 vs. 3226, p < 0.0001), a significantly lower median of PlGF (33.92 vs. 115.2, p < 0.0001) and PlGF% (-76.63 vs. -20.31, p < 0.0001) were demonstrated, respectively, when preeclampsia with small-for-gestational age and/or low birth weight neonates was compared with preeclampsia with normal birth weight neonates. No significant difference was demonstrated between low birth weight and small-for-gestational age on sFlt-1/PlGF, PlGF, PlGF%, and sFlt-1.Conclusion: sFlt-1/PlGF seems to be a promising biomarker in predicting low birth weight and/or small-for-gestational age neonates in pregnancy with or without preeclampsia.","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"15 1","pages":"e36-e42"},"PeriodicalIF":0.8,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11957859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Duodenal Peptic Ulcer Perforation in the Puerperium Case Report Series. 产褥期十二指肠消化性溃疡穿孔病例报告系列。

IF 0.8

AJP Reports Pub Date : 2025-03-04 eCollection Date: 2025-01-01 DOI: 10.1055/a-2533-2017

Elizabeth Stiles, Andre Robinson, Erin Fitzgerald, Marie Fleury, Andrew Rubenstein

引用次数: 0

Lower Gastrointestinal Bleeding, Vomiting, and Weight Stagnation in a Well-Appearing Neonate with Neonatal Transient Eosinophilic Gastroenterocolitis. 下消化道出血，呕吐和体重停滞在新生儿短暂性嗜酸性胃肠炎表现良好的新生儿。

IF 0.8

AJP Reports Pub Date : 2025-02-20 eCollection Date: 2025-01-01 DOI: 10.1055/a-2531-4618

Bernat Servitje-Verdaguer, Clara Comalrena-de-Sobregrau-Martínez, Carmen-María Sánchez-Molina, Joan-Carles Ferreres-Piñas, Núria Torre-Monmany, Diana García-Tirado

引用次数: 0

Living Near Wildfires and the Risk of Fetal Congenital Heart Defects: Evaluating Critical Windows of Vulnerability. 生活在森林大火附近和胎儿先天性心脏缺陷的风险：评估脆弱的关键窗口。

IF 0.8

AJP Reports Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.1055/a-2528-3588

Bo Y Park, Kriti Vedhanayagam, Jared Ortiz-Luis, Rupa Basu, Ciprian P Gheorghe, Shravya Govindappagari, Ray Abinader, Ruofan Yao

{"title":"Living Near Wildfires and the Risk of Fetal Congenital Heart Defects: Evaluating Critical Windows of Vulnerability.","authors":"Bo Y Park, Kriti Vedhanayagam, Jared Ortiz-Luis, Rupa Basu, Ciprian P Gheorghe, Shravya Govindappagari, Ray Abinader, Ruofan Yao","doi":"10.1055/a-2528-3588","DOIUrl":"10.1055/a-2528-3588","url":null,"abstract":"Background Wildfires produce air pollutants that have been associated with complications during pregnancy. This study examined the association between wildfire exposure before and during pregnancy and the odds of congenital heart defect (CHD) in the offspring. Methods This retrospective cohort study used the California Linked Birth File and the Forestry and Fire Protection data between 2007 and 2010. Patients living within 15 miles of wildfire during pregnancy were considered exposed. Multivariate logistic regression models were used to estimate the association between wildfire exposure by these various exposure metrics and atrial septal defect (ASD) or ventricular septal defect (VSD) types of CHD compared to pregnancies without wildfire exposure. Results Compared to births without wildfire exposure, those with first-, second-, and third-trimester exposure were associated with a higher risk of ASD with a first-trimester adjusted odds ratio (aOR) of 1.11 (95% confidence interval (CI): 1.04-1.18), second-trimester aOR of 1.12 (95% CI: 1.07-1.18), and third-trimester aOR of 1.08 (95% CI: 1.02-1.14). Wildfire exposure during the critical window of fetal heart development (weeks 3-8) was associated with aOR of 1.12 (95% CI: 1.02-1.23). Conclusion Wildfire exposure during pregnancy appears to increase the risk of developing ASD. Key points Wildfire exposure during critical periods in pregnancy are associated with congenital cardiac malformation.Pre-pregnancy exposure to wildfire is not associated with increased risk of congenital cardiac malformation.Pregnant individuals should avoid wildfire exposure.","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"15 1","pages":"e18-e24"},"PeriodicalIF":0.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11825217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

" Trying to Grab Pieces of Hope " : Exploring the Experiences of Black and Hispanic Parents following a Congenital Heart Disease Diagnosis. “试图抓住希望的碎片”：探索先天性心脏病诊断后黑人和西班牙裔父母的经历。

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AJP Reports Pub Date : 2025-01-07 eCollection Date: 2025-01-01 DOI: 10.1055/a-2504-1813

Sharla Rent, Kwai Tei Candy Chan Poon, Meredith Sooy-Mossey, Mary Frances Weeks, James C Roberts, Dakota Douglas, Sarah Ellestad, Monica E Lemmon, Kevin Hill, McAllister Windom

{"title":"\" Trying to Grab Pieces of Hope \" : Exploring the Experiences of Black and Hispanic Parents following a Congenital Heart Disease Diagnosis.","authors":"Sharla Rent, Kwai Tei Candy Chan Poon, Meredith Sooy-Mossey, Mary Frances Weeks, James C Roberts, Dakota Douglas, Sarah Ellestad, Monica E Lemmon, Kevin Hill, McAllister Windom","doi":"10.1055/a-2504-1813","DOIUrl":"https://doi.org/10.1055/a-2504-1813","url":null,"abstract":"Objective Congenital heart disease (CHD) is an important contributor to pediatric morbidity and mortality. Unfortunately, disparities in the diagnosis and treatment of CHD exist across racial and ethnic groups. The objective of this study was to share the experiences of Hispanic and Black families with CHD to better understand their needs. Study Design This was a descriptive qualitative study involving two 2-part focus groups, one conducted in English and one in Spanish, consisting of parents of infants with CHD. Focus groups were audio recorded, transcribed, and analyzed via a conventional content analysis approach. Results Six family members participated, representing a range of cardiac diagnoses. Two participants cited their identity as non-Hispanic Black and four as Hispanic. Three organizing themes emerged related to (1) communication, (2) psychosocial needs and processing, and (3) practical challenges associated with having a child with CHD. Together, these organizing themes supported a singular global theme: structural and socioemotional gaps in care exist for families of infants with CHD that need to be met in order to optimize care for patients and families. Conclusion Societal and systems-level factors, including structural inequities, contribute to the care gaps experienced by racial and ethnic minority families of children with CHD. Key Points Poor communication around CHD diagnosis impairs provider-patient trust.Language barriers hinder accurate communication about CHD diagnosis and treatment.Parents of children with CHD have unmet mental health needs.Perinatal providers should champion health equity for CHD patients and their families.","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"15 1","pages":"e6-e17"},"PeriodicalIF":0.8,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Prolonged Antenatal Intravenous Immunoglobulin Treatment in Preventing Gestational Alloimmune Liver Disease-A Case Series with Literature Review. 延长产前静脉注射免疫球蛋白治疗在预防妊娠期同种免疫性肝病中的作用——病例系列并文献复习。

IF 0.8

AJP Reports Pub Date : 2025-01-07 eCollection Date: 2025-01-01 DOI: 10.1055/a-2496-8690

Eena Sunya Lin, Faraz Afridi, Sukrita Sheshu Mysore, Thomas Presenza, Alla Kushnir, Rafat Ahmed

{"title":"The Effect of Prolonged Antenatal Intravenous Immunoglobulin Treatment in Preventing Gestational Alloimmune Liver Disease-A Case Series with Literature Review.","authors":"Eena Sunya Lin, Faraz Afridi, Sukrita Sheshu Mysore, Thomas Presenza, Alla Kushnir, Rafat Ahmed","doi":"10.1055/a-2496-8690","DOIUrl":"https://doi.org/10.1055/a-2496-8690","url":null,"abstract":"Background Gestational alloimmune liver disease (GALD) is characterized by maternal IgG-directed fetal hepatocyte damage and can lead to severe liver failure and fetal or infant death. Moreover, GALD is associated with a near 90% risk of recurrence in subsequent pregnancies. Case We present a case of a newborn patient delivered to a 32-year-old G2P1000 mother who received prolonged antenatal intravenous immunoglobulin (IVIG) treatment during the current pregnancy due to the neonatal death of the first child from GALD-related liver failure. Postnatal testing, including a liver magnetic resonance imaging (MRI) and buccal biopsy of this newborn, showed normal morphology of the liver without any abnormal iron deposition. Additional laboratory testing showed a lack of any liver injury. Conclusion This case supports the use of antenatal IVIG immunotherapy to prevent the recurrence of GALD in subsequent pregnancies. Key Points GALD can lead to severe fetal liver injury.GALD is highly recurrent in subsequent pregnancies.Prophylactic IVIG may prevent GALD recurrence.","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"15 1","pages":"e1-e5"},"PeriodicalIF":0.8,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Case of Fetal Neural Tube Defect; Iniencephaly Clausus. 罕见的胎儿神经管缺损1例Iniencephaly Clausus。

IF 0.8

AJP Reports Pub Date : 2024-12-26 eCollection Date: 2024-07-01 DOI: 10.1055/a-2496-2417

Bantayehu Nega Arega, Sintayehu Debas Endalew, Daniel Miskir Hailu

引用次数: 0

Human Milk-Derived Fortifier to Reduce Hospital-Acquired Malnutrition in Uncomplicated Gastroschisis: A Case Report. 人乳衍生强化剂减少无并发症胃裂患者医院获得性营养不良1例报告。

IF 0.8

AJP Reports Pub Date : 2024-12-23 eCollection Date: 2024-07-01 DOI: 10.1055/a-2490-3521

Anna Strle, Sarah M Reyes, Megan Schmidt, Mary Frances Lynch

{"title":"Human Milk-Derived Fortifier to Reduce Hospital-Acquired Malnutrition in Uncomplicated Gastroschisis: A Case Report.","authors":"Anna Strle, Sarah M Reyes, Megan Schmidt, Mary Frances Lynch","doi":"10.1055/a-2490-3521","DOIUrl":"10.1055/a-2490-3521","url":null,"abstract":"Gastroschisis is one of the most common congenital gastrointestinal disorders, occurring in about one in 1,953 infants born each year in the United States. Infants with gastroschisis rely on total parenteral nutrition (TPN) preoperatively, and due to intestinal function and dysmotility issues, continue to face feeding challenges postclosure, including feeding intolerance and increased risk of necrotizing enterocolitis (NEC). Postclosure, human milk-feeding is preferred over infant formula because of its associated reduced risk of feeding intolerance and NEC. However, unfortified human milk often falls short of meeting the increased metabolic demands of these postsurgical infants in the first few weeks of life, leading to hospital-acquired malnutrition (undernutrition) as TPN is weaned. We hypothesized that fortifying maternal milk with human milk-based fortifiers would mitigate the risk of hospital-acquired malnutrition while providing the tolerance benefits of an exclusive human milk diet, specifically by meeting the increased energy and protein demands of the immediate postsurgical infant as parenteral nutrition is weaned. The case report describes our unit's use of a human milk-based fortifier in an infant with uncomplicated gastroschisis and its positive effect on the patient's growth. Further research is warranted to assess the use of human milk-derived fortifiers to prevent hospital-acquired malnutrition after gastrointestinal surgery.","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 4","pages":"e275-e280"},"PeriodicalIF":0.8,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0