AJP ReportsPub Date : 2025-01-07eCollection Date: 2025-01-01DOI: 10.1055/a-2504-1813
Sharla Rent, Kwai Tei Candy Chan Poon, Meredith Sooy-Mossey, Mary Frances Weeks, James C Roberts, Dakota Douglas, Sarah Ellestad, Monica E Lemmon, Kevin Hill, McAllister Windom
{"title":"\" <i>Trying to Grab Pieces of Hope</i> \" <i>:</i> Exploring the Experiences of Black and Hispanic Parents following a Congenital Heart Disease Diagnosis.","authors":"Sharla Rent, Kwai Tei Candy Chan Poon, Meredith Sooy-Mossey, Mary Frances Weeks, James C Roberts, Dakota Douglas, Sarah Ellestad, Monica E Lemmon, Kevin Hill, McAllister Windom","doi":"10.1055/a-2504-1813","DOIUrl":"https://doi.org/10.1055/a-2504-1813","url":null,"abstract":"<p><p><b>Objective</b> Congenital heart disease (CHD) is an important contributor to pediatric morbidity and mortality. Unfortunately, disparities in the diagnosis and treatment of CHD exist across racial and ethnic groups. The objective of this study was to share the experiences of Hispanic and Black families with CHD to better understand their needs. <b>Study Design</b> This was a descriptive qualitative study involving two 2-part focus groups, one conducted in English and one in Spanish, consisting of parents of infants with CHD. Focus groups were audio recorded, transcribed, and analyzed via a conventional content analysis approach. <b>Results</b> Six family members participated, representing a range of cardiac diagnoses. Two participants cited their identity as non-Hispanic Black and four as Hispanic. Three organizing themes emerged related to (1) communication, (2) psychosocial needs and processing, and (3) practical challenges associated with having a child with CHD. Together, these organizing themes supported a singular global theme: structural and socioemotional gaps in care exist for families of infants with CHD that need to be met in order to optimize care for patients and families. <b>Conclusion</b> Societal and systems-level factors, including structural inequities, contribute to the care gaps experienced by racial and ethnic minority families of children with CHD. <b>Key Points</b> Poor communication around CHD diagnosis impairs provider-patient trust.Language barriers hinder accurate communication about CHD diagnosis and treatment.Parents of children with CHD have unmet mental health needs.Perinatal providers should champion health equity for CHD patients and their families.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"15 1","pages":"e6-e17"},"PeriodicalIF":0.8,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2025-01-07eCollection Date: 2025-01-01DOI: 10.1055/a-2496-8690
Eena Sunya Lin, Faraz Afridi, Sukrita Sheshu Mysore, Thomas Presenza, Alla Kushnir, Rafat Ahmed
{"title":"The Effect of Prolonged Antenatal Intravenous Immunoglobulin Treatment in Preventing Gestational Alloimmune Liver Disease-A Case Series with Literature Review.","authors":"Eena Sunya Lin, Faraz Afridi, Sukrita Sheshu Mysore, Thomas Presenza, Alla Kushnir, Rafat Ahmed","doi":"10.1055/a-2496-8690","DOIUrl":"https://doi.org/10.1055/a-2496-8690","url":null,"abstract":"<p><p><b>Background</b> Gestational alloimmune liver disease (GALD) is characterized by maternal IgG-directed fetal hepatocyte damage and can lead to severe liver failure and fetal or infant death. Moreover, GALD is associated with a near 90% risk of recurrence in subsequent pregnancies. <b>Case</b> We present a case of a newborn patient delivered to a 32-year-old G2P1000 mother who received prolonged antenatal intravenous immunoglobulin (IVIG) treatment during the current pregnancy due to the neonatal death of the first child from GALD-related liver failure. Postnatal testing, including a liver magnetic resonance imaging (MRI) and buccal biopsy of this newborn, showed normal morphology of the liver without any abnormal iron deposition. Additional laboratory testing showed a lack of any liver injury. <b>Conclusion</b> This case supports the use of antenatal IVIG immunotherapy to prevent the recurrence of GALD in subsequent pregnancies. <b>Key Points</b> GALD can lead to severe fetal liver injury.GALD is highly recurrent in subsequent pregnancies.Prophylactic IVIG may prevent GALD recurrence.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"15 1","pages":"e1-e5"},"PeriodicalIF":0.8,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2024-12-26eCollection Date: 2024-07-01DOI: 10.1055/a-2496-2417
Bantayehu Nega Arega, Sintayehu Debas Endalew, Daniel Miskir Hailu
{"title":"A Rare Case of Fetal Neural Tube Defect; Iniencephaly Clausus.","authors":"Bantayehu Nega Arega, Sintayehu Debas Endalew, Daniel Miskir Hailu","doi":"10.1055/a-2496-2417","DOIUrl":"10.1055/a-2496-2417","url":null,"abstract":"<p><p><b>Introduction</b> Iniencephaly is an extremely rare type of neural tube defect characterized by the fusion of the cervical and cervicothoracic vertebrae. This condition results in acute retroflexion of the head, a short neck, significant lordosis of the cervical spine, and an upturned facial appearance. This condition typically results in poor fetal outcomes, with many cases ending in stillbirth or neonatal death. <b>Case summary</b> Here, we present a case of iniencephaly diagnosed during intrapartum ultrasound in a 34-year-old gravida 5 woman referred from a health center to a primary hospital due to preterm premature rupture of membrane and labor. The fetus died intrapartum a few minutes before delivery. <b>Conclusion</b> Iniencephaly remains a rare but critical condition that poses significant challenges for prenatal diagnosis and management. This case underscores the importance of early and accurate imaging in the detection of such severe anomalies, which can provide essential information for clinical decision-making and counseling.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 4","pages":"e281-e283"},"PeriodicalIF":0.8,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2024-12-23eCollection Date: 2024-07-01DOI: 10.1055/a-2490-3521
Anna Strle, Sarah M Reyes, Megan Schmidt, Mary Frances Lynch
{"title":"Human Milk-Derived Fortifier to Reduce Hospital-Acquired Malnutrition in Uncomplicated Gastroschisis: A Case Report.","authors":"Anna Strle, Sarah M Reyes, Megan Schmidt, Mary Frances Lynch","doi":"10.1055/a-2490-3521","DOIUrl":"10.1055/a-2490-3521","url":null,"abstract":"<p><p>Gastroschisis is one of the most common congenital gastrointestinal disorders, occurring in about one in 1,953 infants born each year in the United States. Infants with gastroschisis rely on total parenteral nutrition (TPN) preoperatively, and due to intestinal function and dysmotility issues, continue to face feeding challenges postclosure, including feeding intolerance and increased risk of necrotizing enterocolitis (NEC). Postclosure, human milk-feeding is preferred over infant formula because of its associated reduced risk of feeding intolerance and NEC. However, unfortified human milk often falls short of meeting the increased metabolic demands of these postsurgical infants in the first few weeks of life, leading to hospital-acquired malnutrition (undernutrition) as TPN is weaned. We hypothesized that fortifying maternal milk with human milk-based fortifiers would mitigate the risk of hospital-acquired malnutrition while providing the tolerance benefits of an exclusive human milk diet, specifically by meeting the increased energy and protein demands of the immediate postsurgical infant as parenteral nutrition is weaned. The case report describes our unit's use of a human milk-based fortifier in an infant with uncomplicated gastroschisis and its positive effect on the patient's growth. Further research is warranted to assess the use of human milk-derived fortifiers to prevent hospital-acquired malnutrition after gastrointestinal surgery.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 4","pages":"e275-e280"},"PeriodicalIF":0.8,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2024-12-17eCollection Date: 2024-07-01DOI: 10.1055/s-0044-1801260
Chad A Grotegut, Kristin E Weaver, Lena Fried, Sarah K Dotters-Katz, Jennifer B Gilner
{"title":"Corrigendum: The Collection and Application of Autologous Amniotic Fluid to Cesarean Delivery Closure.","authors":"Chad A Grotegut, Kristin E Weaver, Lena Fried, Sarah K Dotters-Katz, Jennifer B Gilner","doi":"10.1055/s-0044-1801260","DOIUrl":"https://doi.org/10.1055/s-0044-1801260","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1055/a-2445-7954.].</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 4","pages":"e274"},"PeriodicalIF":0.8,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2024-11-26eCollection Date: 2024-07-01DOI: 10.1055/a-2447-8662
Trassanee Chatmethakul, Amy H Stanford, Danielle R Rios, Adrianne R Bischoff, Theresa Czech, Patrick J McNamara
{"title":"Cardiac Dysfunction Associated with Lacosamide in a Premature Infant with Hypoxic Ischemic Encephalopathy: A Case Report.","authors":"Trassanee Chatmethakul, Amy H Stanford, Danielle R Rios, Adrianne R Bischoff, Theresa Czech, Patrick J McNamara","doi":"10.1055/a-2447-8662","DOIUrl":"10.1055/a-2447-8662","url":null,"abstract":"<p><p>Lacosamide (Vimpat Harris FRC Corporation, 2022 UCB, Inc. Smyrna, GA 30080) is an antiseizure medication, which acts through blockage of voltage-gated neuronal sodium channels. Its recent implementation in the neonatal population has been extrapolated from adult and pediatric data suggesting a favorable safety profile. Of note, preterm infants have unique developmental characteristics that may predispose them to increased risk of adverse reactions. We present a case of a preterm neonate who developed left ventricular dysfunction coinciding with the initiation of lacosamide.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 4","pages":"e270-e273"},"PeriodicalIF":0.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11597592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2024-11-12eCollection Date: 2024-07-01DOI: 10.1055/a-2441-4217
Gloria Akuamoah-Boateng, Kayla A Buttafuoco, Courtney C Sutton, Brian P Hackett
{"title":"Neuroleptic Malignant Syndrome in a 10-Month-Old Ex-Preterm Infant with Delirium.","authors":"Gloria Akuamoah-Boateng, Kayla A Buttafuoco, Courtney C Sutton, Brian P Hackett","doi":"10.1055/a-2441-4217","DOIUrl":"https://doi.org/10.1055/a-2441-4217","url":null,"abstract":"<p><p>In recent times, atypical antipsychotics are increasingly being used in the neonatal intensive care unit (NICU) for the management of neonatal delirium. As the recognition of delirium in NICU infants increases, caution should be exercised with use of antipsychotics for management, given associated adverse effects. Neuroleptic malignant syndrome (NMS) is a rare adverse drug reaction associated with exposure to antipsychotics and other antidopaminergic medications. Most reported cases of NMS in pediatric patients have been in older children on antipsychotic medications. We present a case of a 10-month-old former preterm infant who developed clinical signs suggestive of NMS after exposure to olanzapine for treatment of delirium. Our case report details the clinical course of this infant, delves into the condition, and outlines some useful lessons for the clinician in the identification and management of this rare but life-threatening adverse effect. <b>Key Points</b> NMS is a rare side effect of antipsychotic medications.Hyperthermia with mental status changes could be due to NMS.Antipsychotics should be used cautiously in infants.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 4","pages":"e259-e261"},"PeriodicalIF":0.8,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2024-10-22eCollection Date: 2024-07-01DOI: 10.1055/a-2434-5650
Nicholas Racchi, Lisa Bird, Samantha Mullan, William Schnettler, Nanci Billock
{"title":"Hemorrhaging Uterine Fibroid Leading to Emergent Early Term Cesarean Delivery: A Case Report.","authors":"Nicholas Racchi, Lisa Bird, Samantha Mullan, William Schnettler, Nanci Billock","doi":"10.1055/a-2434-5650","DOIUrl":"https://doi.org/10.1055/a-2434-5650","url":null,"abstract":"<p><p><b>Background</b> The incidence of uterine leiomyomas, or fibroids, affecting pregnant individuals is estimated to be 10%, but there are no guidelines or recommendations for fetal or maternal surveillance in pregnancies affected by them. Risks associated with fibroids during pregnancy include potential for pain, preterm birth, fetal growth restriction, higher cesarean delivery rate, fetal malpresentation, placenta abruption, and postpartum hemorrhage. <b>Case Presentation</b> This case describes a 26-year-old gravida 1 para 0 who presented at early term for severe abdominal pain and was found to have acute abdomen accompanied by a nonreassuring fetal heart rate tracing. With emergent cesarean delivery, it was found that the patient was hemorrhaging from a ruptured vessel of a pedunculated fibroid and myomectomy was subsequently performed. <b>Conclusion</b> While rare, hemorrhage from a uterine fibroid should be considered a part of the differential diagnosis of abdominal pain in pregnant patients with fibroids, particularly when accompanied by concurrent indicators such as free fluid, hypotension/tachycardia, or concerning changes in fetal heart rate, especially in a patient without risk factors for uterine rupture.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 4","pages":"e250-e253"},"PeriodicalIF":0.8,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2024-10-11eCollection Date: 2024-07-01DOI: 10.1055/a-2413-2465
Nigel Madden, Nevin Kamal, Jared Friedman, Priya Freaney, Susan E Gerber, Emily D Szmuilowicz
{"title":"Obstetrical Management of Severe Hypertriglyceridemia in Pregnancy: A Case Report.","authors":"Nigel Madden, Nevin Kamal, Jared Friedman, Priya Freaney, Susan E Gerber, Emily D Szmuilowicz","doi":"10.1055/a-2413-2465","DOIUrl":"https://doi.org/10.1055/a-2413-2465","url":null,"abstract":"<p><p><b>Background</b> Pregnant people with baseline hypertriglyceridemia are at increased risk of severe hypertriglyceridemia and the associated complications, yet there are no formal recommendations to guide management of these patients during pregnancy. <b>Case</b> We report a case of a patient with presumed familial hypertriglyceridemia who was taken off triglyceride-lowering medications preconception and developed acute pancreatitis at 23 weeks of gestation. She was managed with a very-low-fat diet, exercise, fenofibrate, omega-3-fatty acids, pravastatin, insulin infusion, and plasmapheresis. She delivered at 33 weeks of gestation after presenting with a placental abruption and subcapsular liver hematoma associated with HELLP (hemolysis, elevated liver enzyme levels, and low platelet) syndrome. <b>Conclusion</b> While rare in pregnancy, severe hypertriglyceridemia is associated with serious maternal risks. Preconception and antepartum obstetric management should incorporate shared decision-making considering both the potential fetal risks of treatment and the objective maternal risks of untreated disease.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 4","pages":"e244-e249"},"PeriodicalIF":0.8,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11469918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2024-10-08eCollection Date: 2024-07-01DOI: 10.1055/a-2415-5318
Anna E Sagaser, Ashley Reeves, Tamara Arnautovic, Juan Sanchez-Esteban
{"title":"Distinction between Pneumothorax and Pneumomediastinum Using Point of Care Ultrasound (POCUS): Role of Still Lung Point.","authors":"Anna E Sagaser, Ashley Reeves, Tamara Arnautovic, Juan Sanchez-Esteban","doi":"10.1055/a-2415-5318","DOIUrl":"10.1055/a-2415-5318","url":null,"abstract":"<p><p>The rapid identification and management of air leak syndrome in the neonatal intensive care unit is critical to prevent and/or minimize short- and long-term complications. Traditionally, chest X-ray is used to diagnose pneumothorax or pneumomediastinum. However, point-of-care ultrasound is increasingly being used for procedural and diagnostic purposes. Current ultrasound guidelines recommend specific criteria to diagnose pneumothorax in newborns including sharp A-lines, absence of B-lines, lack of shimmering of the pleural line, and the presence of a lung point. Pneumomediastinum may have similar ultrasound characteristics. In this case report, we present two cases of pneumomediastinum in newborns, describe the associated ultrasound findings, and review some of the criteria to differentiate from pneumothorax, including the presence of a still lung point. A high index of suspicion for pneumomediastinum should be maintained when using ultrasound to diagnose air leak given the overlapping sonographic features with pneumothorax. This distinction is of particular importance if evacuation of air by needle thoracentesis or the placement of a chest tube is under consideration.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"14 3","pages":"e239-e243"},"PeriodicalIF":0.8,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11461096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}