African journal of medicine and medical sciences最新文献

筛选
英文 中文
Responses to spread of.Ebola virus disease epidemic in West Africa: A review. 对传播的反应。西非埃博拉病毒病流行:综述。
Al Ayede, K Osinusi, A G Falade
{"title":"Responses to spread of.Ebola virus disease epidemic in West Africa: A review.","authors":"Al Ayede,&nbsp;K Osinusi,&nbsp;A G Falade","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The first Ebola virus disease (EVD) epidemic in West Africa is unprecedented in its spread, complexity and severity. Comparing responses to spread of the virus in the three most affected countries - Guinea, Sierra Leone and Liberia- with that in Nigeria, Senegal and Mali where the epidemic was quickly brought under control may guide future mitigation efforts.</p><p><strong>Methods: </strong>Literature from Pubmed. Google,Center for Disease Control and Prevention (CDC), Morbidity and Mortality Weekly Report (MMWR), World Health Organization's Updates and Ebola Response Reports: Results: The epidemic spread undiagnosed for three months from Meliandou in Guinea to its four rural prefectures and its. capital Conakry, two countires in Liberia and two districts in Sierra Leone. Control measures were hampered by traditional and faith healers offering -inappropriate treatments, as well as secret societies encouraging unsafe burial rituals. Whereas, in Nigeria, a case imported from Liberia on 20 July 2014 was diagnosed on the 3rd day; all primary, secondary and tertiary contacts were traced. Also, at a formal meeting, officials of Lagos state government discouraged treatment of EVD by faith healers. In Senegal, a single case imported from Guinea on 20 August 2014 was diagnosed on the 9th day, treated and further spread was prevented. In Mali, there were two waves of transmissions identified on 23 October and 12 November 2014 within 15 days of importation and the epidemic was controlled.There were no cases of EVD treated by any traditional healers or faith healers in Nigeria, Senegal and Mali.</p><p><strong>Conclusion: </strong>Education of traditional and faith healers on EVD will complement control measures for EVD epidemic.</p>","PeriodicalId":7616,"journal":{"name":"African journal of medicine and medical sciences","volume":"45 2","pages":"119-134"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35851766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perception, attitude and willingness of under-five children caregivers to growth monitoring in Ibadan South-West Local Government Area, Oyo State, Nigeria. 尼日利亚奥约州伊巴丹西南地方政府地区五岁以下儿童照料者对生长监测的认知、态度和意愿。
O Abiona, O Oladepo
{"title":"Perception, attitude and willingness of under-five children caregivers to growth monitoring in Ibadan South-West Local Government Area, Oyo State, Nigeria.","authors":"O Abiona,&nbsp;O Oladepo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>This study was carried out to explore perceptions ofunder five caregivers on growth monitoring in Ibadan south-west local government in Nigeria.</p><p><strong>Method: </strong>Descriptive. cross-sectional-design was used for the study which involved four-stage sampling techniques. The study was conducted among the 410 caregivers who consented to participate. Both qualitative and quantitative methods were used to collect the data. The questionnaire elicited information on sociodemographic characteristics, Knowledge, Attitude and Growth -Monitoring perceptions were measured on a 16-point scale and categorizedinto \"negative\" (≤8) and positive (>8) Descriptive statistics -using mean and standard deviation were generated while qualitative data was analysed using Atlas Ti version 7. Result Mean age of the Caregivers of Under-5 was 31.6±6.5 years, 46.8% had secondary education and 56.8% were traders. Majority (88.3%) had received information on Growth Monitoring and (66:6%) heard from the health workers. Almost all the: respondents (90.0%) had positive perception towards Growth Monitoring (10.8±2.9). It was also suggested by the caregivers that their involvement is very crucial in monitoring the growth of their children. Concusion: The study showed that most of the caregivers. had positive perceptions towards growth monitoring and advocated their active involvement if training progriammes can be developed.</p>","PeriodicalId":7616,"journal":{"name":"African journal of medicine and medical sciences","volume":"45 2","pages":"151-158"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35851149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Micronutrient status and its effect on glycaemic indices in type 2 diabetics with foot ulcer in Ibadan, Nigeria. 尼日利亚伊巴丹2型糖尿病足部溃疡患者微量营养素状况及其对血糖指标的影响
E B Bolajokol, O M Akinosui, J I Anetor, K S Mossanda
{"title":"Micronutrient status and its effect on glycaemic indices in type 2 diabetics with foot ulcer in Ibadan, Nigeria.","authors":"E B Bolajokol,&nbsp;O M Akinosui,&nbsp;J I Anetor,&nbsp;K S Mossanda","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Micronutrients are required by organisms in trace concentrations sufficient to maintain homeostasis. Deficiency of these elements could result in different medical and metabolic abnormalities. There are limited data on micronutrient status in type 2 diabetics with foot ulcer (DM+FU). Premised on this, this study investigated micronutrient levels of DM+FU and examined their effects on glycaemic indices.</p><p><strong>Methods: </strong>One hundred and twenty participants, comprising seventy DM+FU and fifty non-diabetic participants (controls) aged 40-60 years, were recruited for the study. Ten millilitres of fasting blood samples were collected from each participant after obtaining their consent and levels of vitamin C, vitamin E, copper, selenium, zinc, FPG and HbAlc were measured. The data were analyzed using 't'- test and Pearson's correlation coefficients. Statistical significant was considered at p<0.05.</p><p><strong>Results: </strong>FPG and HbAlc were significantly higher in DM+FU (12.98±0.43 mmol/l; 8.63±0.24 %) than in controls (5.09±0.08 mmol/l; 4.08±0.11 %). Vitamin C (3.7610.43 vs. 5.57±0.43 ptmol/l; p=0.003), vitamin E (19.57±1.01 vs. 25.57±0.27 pLimol/l; p=0.000) and selenium (0.48±0.01 vs. 0.81±0.04 srmol/l; p=0.000) were substantially lower in DM+FU compared with controls. However, no significant changes were observed when levels of copper and zinc were compared in all participants. Data revealed inverse associations between micronutrients and glycaemic indices (vitamin C/ FPG: (r= 0.250, p=0.037); Cu/HbA Ic: (r= 0.131, p=0.365)).</p><p><strong>Conclusions: </strong>Diabetics with foot ulcer were observed to be deficient in selenium, vitamin C and vitamin E. Therefore, type 2 diabetics with foot ulcer should be advised and encouraged to take more of leafy green vegetables and unsweetened fruits.</p>","PeriodicalId":7616,"journal":{"name":"African journal of medicine and medical sciences","volume":"45 1","pages":"83-90"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35150128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oxygen for children and newborns in non-tertiary hospitals in South-west Nigeria: A needs assessment. 尼日利亚西南部非三级医院为儿童和新生儿提供氧气:需求评估。
H R Graham, A I Ayede, A A Bakare, O B Oyewole, D Peel, A G Falade, T Duke
{"title":"Oxygen for children and newborns in non-tertiary hospitals in South-west Nigeria: A needs assessment.","authors":"H R Graham,&nbsp;A I Ayede,&nbsp;A A Bakare,&nbsp;O B Oyewole,&nbsp;D Peel,&nbsp;A G Falade,&nbsp;T Duke","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Oxygen is important for the treatment of hypoxaemia associated with pneumonia, malaria, and other medical, obstetric, and surgical conditions. Access to oxygen therapy is limited in many of the high mortality settings where it would be of most benefit.</p><p><strong>Methods: </strong>A needs assessment of 12 non-tertiary hospitals in south-west Nigeria, assessing structural, technical and clinical barriers to the provision of safe and effective oxygen therapy.</p><p><strong>Results: </strong>Oxygen supply was reported to be a major challenge by hospital directors. All hospitals had some access to oxygen cylinders, which were expensive and frequently ran out. Nine (75%) hospitals used oxygen concentrators, which were limited by inadequate power supply and lack of maintenance capacity. Appropriate oxygen delivery and monitoring devices (nasal prongs, catheters, pulse oximeters) were poorly available, and no hospitals had clinical guidelines pertaining to the use of -oxygen for children. Oxygen was expensive to patients (median US$20/day) and to hospitals. Estimated oxygen demand is reported using both a constant mean-based estimate and adjustment for seasonal and other variability.</p><p><strong>Conclusions: </strong>Making oxygen available to sick children and neonates in Nigerian hospitals will require: improving detection of hypoxaemia through routine use of pulse oximetry; improving access to oxygen through equipment, training, and maintenance structures; and commitment to building hospital and state structures that can sustain and expand oxygen initiatives.</p>","PeriodicalId":7616,"journal":{"name":"African journal of medicine and medical sciences","volume":"45 1","pages":"31-49"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35149678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overview of radiation dose to patients from medical X-ray examinations in Nigeria. 尼日利亚医学x射线检查对患者的辐射剂量概述。
B I Akinlade, F B Odefemi, I P Farai
{"title":"Overview of radiation dose to patients from medical X-ray examinations in Nigeria.","authors":"B I Akinlade,&nbsp;F B Odefemi,&nbsp;I P Farai","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>Medical Imaging accounts for the largest radiation exposure of population from artificial sources of radiation. The radiation dose rcceivedby patients from iedicail x-ray examinations in Nigeria has shown large variations within and among diagnostic centers for similar examinations. This could be traced to lack of imaging protocols and on avalability of local/national diagnostic reference, levels. Hence, the need to assess the trend of radiation doseto patients from radiological practice in Nigeria. Methocls:Entrance surface doses(ESDs) reported by, Nigerian authors for common x-ray examinations from 2000 - 2014 were extracted from articles published in peer reviewed journals, analyzed and compared with ifiternationally recommended Diagnostic Reference Levels (DkLs).</p><p><strong>Results: </strong>Among x-ray examinations, skull accounted for 32% followed by chest (22%), lumbar spine (13%), abdomen (12%), pelvis (8%), extremitics(8%), thorax and cervical spine(5%). The range of mean ESDs reported for various projections of x-ray examination are chest (2.28 - 3.70 mGy); Abdomen (4.42 - 7.22 mGy); Skull (3.81 - 5.19 mGy); Pelvis (5.93 mGy); Lumbar spine (5.73 - 10.98 mGy); Thorax (0.96 - 1.85 mGy); Cervical spine (1.45 - 1.49mGy) and Extremitics (0.31 -0.49 mGy). In this study, it was found that the mean ESDs received by patients from chest, skull and pelvis ex'aminations were higher than the published DRLs for similar x-ray examinations.</p><p><strong>Conclusion: </strong>The results of this study showed that to harmonize radiation protection of patients and improve radiological practice in Nigeria there is need for development of comprehensive national diagnostic reference levels.</p>","PeriodicalId":7616,"journal":{"name":"African journal of medicine and medical sciences","volume":"45 1","pages":"23-29"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35149676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is there any relationship between hearing threshold levels and CD4 cell count of human immunodeficiency virus infected adults? 人类免疫缺陷病毒感染成人的听阈水平与CD4细胞计数之间是否有关系?
A J Fasunla, J O Ijitola, O M Akpa, O G B Nwaorgu, B Taiwo, D O Olaleye, R L Murphy, I F Adewole, O O Akinyinka
{"title":"Is there any relationship between hearing threshold levels and CD4 cell count of human immunodeficiency virus infected adults?","authors":"A J Fasunla,&nbsp;J O Ijitola,&nbsp;O M Akpa,&nbsp;O G B Nwaorgu,&nbsp;B Taiwo,&nbsp;D O Olaleye,&nbsp;R L Murphy,&nbsp;I F Adewole,&nbsp;O O Akinyinka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Background The role of viral load level and/or CD4 (Cluster of differentiation 4) cell count in the aetiopathogenesis of hearing loss in HIV infection is unclear. Therefore, we investigated the relationship between CD4 cell counts, viral load and hearing threshold of HIV (Human immunodeficiency virus) infected adults.</p><p><strong>Methods: </strong>This cohort audiometric study involved consecutive HIV-infected and HIV-uninfected adults as controls. Clinical data relating to hearing loss, HIV status, and highly -active antiretroviral therapy (HAART) were obtained. Audiornetric evaluation was performed. The most recent CD4 cell counts and RNA viral load-of HIV-infected participants were obtained from clinic records.</p><p><strong>Results: </strong>There were 299(66.7%) HIV-infected adults and 149(33.3%) controls with mean age of 39.64± 12.45 years and 39.60±12.45 years respectively (p=0.98). In both groups, there were more participants with left hearing loss. Mild to profound hearing loss was found in 65.9% HIV- infected participants and 53.7% controls. Majority (86.3%) of the HIV-infected participants were on HAART. The mean CD4 cell count was 654.58±289.15 in 41 HIV-infected participants not on HAART and 523.95±300.17 in 258 participants on HAART (p=0.01). Majority,- 197 (62%) HIV- infected participants with hearing loss had CD4 cell count ≤200 cells/mm3. Higher viral load significantly correlated with low CD4 cell counts (p<0.0 1; r=0. 18) and low CD4 cell count significantly correlated with high hearing threshold (p<O.01; r=0. 17).</p><p><strong>Conclusion: </strong>There was a trend towards more hearing loss among the HIV-infected adults. The higher hearing threshold in those with low CD4 cell counts of <200 cells/mm3 suggests possible relationship between hearing status and severity of HIV disease.</p>","PeriodicalId":7616,"journal":{"name":"African journal of medicine and medical sciences","volume":"45 1","pages":"51-60"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35149679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevlaence of chronic kidney disease markers in Kumbotso rural Northern Nigeria. 尼日利亚北部Kumbotso农村地区慢性肾病标志物的流行情况
A Nalado, A Abdu, B Adamu, M H Aliyu, F A Arogundade, A A Sanusi, S S Wali, A Akinsola
{"title":"Prevlaence of chronic kidney disease markers in Kumbotso rural Northern Nigeria.","authors":"A Nalado,&nbsp;A Abdu,&nbsp;B Adamu,&nbsp;M H Aliyu,&nbsp;F A Arogundade,&nbsp;A A Sanusi,&nbsp;S S Wali,&nbsp;A Akinsola","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Data- on the epidemiology of Chronic Kidney Disease (CKD) from sub-SaharanAfrica are sparse. We investigated the prevalence of CKD and its early markers in Kumbotso, a rural community in northern Nigeria.</p><p><strong>Methods: </strong>A total of 480 individuals were randomly selected from the general population using multistage stratified random sampling. Relevant- demographic and clinical data were obtained using a structured questionnaire. Biological samples (urine and blood) were drawn for relevant investigations.</p><p><strong>Results: </strong>CKD (estimated glomerular filtration rate [eGFR <60 mls/min) was found in 117 participants (26%). Proteinuria was present in 106 persons (23.6%) and haematuria in 7 individuals (1.6%). The most common CKD stage was stage 1 (20%). CKD was associated with hypertension (P=0.002), diabetes (P=0.001), high cholesterol (P=0.030), smoking (P=0.015), increasing BMI (P=0.020), and increasing age (P=0.003). After adjusting for potential confounding with logistic regression modeling we found BMI, family history of hypertension, history of diabetes mellitus and family history of renal disease to be independent predictors of CKD.</p><p><strong>Conclusions: </strong>Early markers of CKD are common among rural inhabitants of northern Nigeria and this call for concerted efforts towards institution of preventive measures.</p>","PeriodicalId":7616,"journal":{"name":"African journal of medicine and medical sciences","volume":"45 1","pages":"61-65"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35149680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug resistance profiles of new- and previously treated patients with pulmonary tuberculosis in Ibadan, Nigeria. 尼日利亚伊巴丹新发和以前接受过治疗的肺结核患者的耐药概况。
A O Kehinde, E O Adebiyi, A O Salako, V O Ogunleye, A A Oni, R A Bakare, O Eltayeb, G Dairo, J Out, F Gehre, T Corrah, A V Deun, M Gumusoboga, E Declercq, T Demeulenaere, B C deJong, M Antonio
{"title":"Drug resistance profiles of new- and previously treated patients with pulmonary tuberculosis in Ibadan, Nigeria.","authors":"A O Kehinde,&nbsp;E O Adebiyi,&nbsp;A O Salako,&nbsp;V O Ogunleye,&nbsp;A A Oni,&nbsp;R A Bakare,&nbsp;O Eltayeb,&nbsp;G Dairo,&nbsp;J Out,&nbsp;F Gehre,&nbsp;T Corrah,&nbsp;A V Deun,&nbsp;M Gumusoboga,&nbsp;E Declercq,&nbsp;T Demeulenaere,&nbsp;B C deJong,&nbsp;M Antonio","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Information on TB drug resistance profiles and its' associated risk factors are scarce in Nigeria despite the large burden of disease in the country. The study was designed to report drug resistance profiles of new- and previously treated patients with pulmonary tuberculosis (TB) in Ibadan, Nigeria.</p><p><strong>Method: </strong>Sputum from consenting pulmonary TB patients were collected and cultured for Mycobacterium tuberculosis (Mtb) at the TB laboratory of the University College Hospital, Ibadan, Nigeria using standard method. Mtb were stored and sent for drug susceptibility testing against first and second-line anti-TB drugs at the MRC Unit, The Gambia and at the Institute of Tropical Medicine, Antwerp, Belgium using BACTEC MGIT 960 and proportion method on solid medium respectively.</p><p><strong>Results: </strong>Of 238 Mtb collected, 124 (52.1%) were viable, 102 (59.65%) non-viable while 12 (7.02%) were contaminated. About half (58.87%) of the Mtb were from previously treated patients, 40 (32.26%) were from new patients while treatment history of 1.1 (8.87%) were unknown. Forty-seven (37.90%) of the 124 Mtb. tested were multidrug resistant (MDR) out of which, 40 (85.10%) were from previously treated patients.. HIV prevalence was 8.69%. Of the 17 MDR-TB from previously treated cases tested for second-line drugs, four (23.53%) were resistant to fluoroquinolones or injectable agents, 13 (76.47%) were susceptible while none was resistant to both of these classes of drugs.</p><p><strong>Conclusion: </strong>MDR-TB in Ibadan already demonstrates resistance to second line anti-TB drugs hence management of MDR-TB patients should be strengthened to prevent emergence of extensively drug-resistant TB (XDR-TB).</p>","PeriodicalId":7616,"journal":{"name":"African journal of medicine and medical sciences","volume":"45 1","pages":"67-73"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35149681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-oxidative and reno-restorative effects of physalis angulata (whole plant extract) in alloxan-induced diabetic male Wistar rats. 角physalis(全植物提取物)对四氧嘧啶诱导的糖尿病雄性Wistar大鼠的抗氧化和肾恢复作用。
E O Adewoye, M A Oguntola, A O Ige
{"title":"Anti-oxidative and reno-restorative effects of physalis angulata (whole plant extract) in alloxan-induced diabetic male Wistar rats.","authors":"E O Adewoye,&nbsp;M A Oguntola,&nbsp;A O Ige","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Backgroiound: Hyperglycemia has been reported to increase protein glycation and generation of free radicals which predispose to diabetic renal dysfunction. Physalis ahgulata has been shown to have hypoglycacmic and anti-lipidemic properties but there is dearth of information regarding its effect on kidney functions in diabetes. This study investigated the anti-oxidative and reno-restorative effects of methanol extract of whole plant of Physalis angulata (MEPA) in alloxan-induced diabetic rats.</p><p><strong>Methodology: </strong>Twenty male Wistar rats (150-180g) were randomly divided into four groups: Group 1 (control) received 0.2 ml distilled water, groups 2-4 were made diabetic by single intra-peritoneal dose of alloxan monohydrate (100mg/kg) and treated with 0.2 ml distilled water, 500 mg/kg MEPA and 150 mg/kg metformin respectively. All treatments were given orally for 14 days. Blood samples were collected from each animal through retro-orbital puncture. The serum obtained were analysed for fructosamine, glycated hemoglobin (HbAlc), creatinine and blood urea nitrogen (BUN). Kidney samples were harvested into cold phosphate buffer, homogenized and centrifuged at- 7500rpm for 15 minutes. The supernatant obtained was analyzed for malondialdehyde and superoxide dismutase (SOD) activities. Values were compared using ANOVA at P<0.05.</p><p><strong>Results: </strong>The MEPA-treated groups showed significant decrease (P<0.05) in blood glucose, kidney weights, fructosamine,. HbAlc, malondialdehyde, creatinine and BUN, while the body weights and SOD significantly increased (P<0.05) compared to diabetic untreated group.</p><p><strong>Conclusion: </strong>Treatment with methanol extract of Physalis angulata (whole plant) reduced hyperglycemia, malondialdehyde and glycation end- products, which could have contributed to the development of diabetic nephropathy if diabetes is left untreated.</p>","PeriodicalId":7616,"journal":{"name":"African journal of medicine and medical sciences","volume":"45 1","pages":"99-108"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35150130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge and practices of nutritional care among day care staff in selected preschools in Ibadan North Local Government Area, Oyo State, Nigeria. 尼日利亚奥约州伊巴丹北部地方政府区选定幼儿园日托人员的营养保健知识和做法
O E Oyewole, I O Dipeolu, M A Muritala
{"title":"Knowledge and practices of nutritional care among day care staff in selected preschools in Ibadan North Local Government Area, Oyo State, Nigeria.","authors":"O E Oyewole,&nbsp;I O Dipeolu,&nbsp;M A Muritala","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Studies have established that growth of children usually falters during the preschool age when the child is usually left in the hands of other care givers; as parents go to work. Feeding of the preschool children is sometimes solely under the care of Day Care Staff (DCS) whoselevel of knowledge and practice of nutritional care is unknown. Knowledge and practices of nutritional care among DCS in selected preschools were investigated.</p><p><strong>Method: </strong>A descriptive cross-sectional study design was used and 400 DCS were randomly selected for interview. A validated questionnaire with 50-point knowledge scale was used to collect information from the target population and this was complemented with observational checklist to assess the level of practice of nutritional care and environmental hygiene. Data obtained were analysed using both univariate and bivariate analyses including Chi-square test at p=0.05 level of significance.</p><p><strong>Results: </strong>Most of the DCS were female (97.5%) and 47.5% specialised in child education. Few (28.8% and 25.0%) of the DCS had ever received training on child nutritional care during pre-service and in- service training, respectively. Only 20.0% of DCS had good knowledge of nutritional care, which reflected in the activities observed. Age was significantly associated with knowledge of preschool nutritional care..</p><p><strong>Conclusion: </strong>Knowledge of day care staff on nutritional care of preschool children was found to be poorer as the age of staff increases. This may also contribute to the poor practices observed. Training on nutritional care among day care staff, especially the older ones is suggested.</p>","PeriodicalId":7616,"journal":{"name":"African journal of medicine and medical sciences","volume":"45 1","pages":"75-82"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35149682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信