Fabio Santanelli di Pompeo, Guido Firmani, Michail Sorotos
{"title":"Behind the Title, Nothing! Reply to: \"The (In-)Ability to Effectively Critique a Method Undermines the Validity of the Criticism\".","authors":"Fabio Santanelli di Pompeo, Guido Firmani, Michail Sorotos","doi":"10.1007/s00266-025-04821-z","DOIUrl":"https://doi.org/10.1007/s00266-025-04821-z","url":null,"abstract":"<p><p>Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Global Bibliometric Visualization of Epidermal Growth Factor in Wound Healing: A Comprehensive Literature Search.","authors":"Sa'ed H Zyoud","doi":"10.1007/s00266-025-04820-0","DOIUrl":"https://doi.org/10.1007/s00266-025-04820-0","url":null,"abstract":"<p><p>Epidermal growth factor (EGF) is essential for both wound repair and the maintenance of healthy tissues. Numerous bibliometric studies have been published on wound healing; however, none have focused on EGF in wound healing. This study comprehensively analyzed scientific publications on the role of Epidermal Growth Factor (EGF) in wound healing. The analysis encompassed publications indexed in the Scopus database from 1972 to 2024, retrieved using a broad range of relevant keywords. Network analysis and visualization were subsequently conducted using VOSviewer (v. 1.6.20) to map research trends and identify research hotspots. My examination of the Scopus database identified 3122 articles on the use of EGF in wound healing published over the past 48 years (1972-2024). Most of these publications were research articles (n = 2812; 90.07%), followed by review articles (n = 244; 7.82%). The number of publications on the use of EGF in wound healing has increased significantly (R<sup>2</sup>=0.9449; p < 0.001) over the years. This study revealed that, during the past ten years, there has been an increasing amount of global research on the relationship between EGF and wound healing. The effectiveness and clinical applications of human EGF and EGFR signaling in cancer-related wound healing were the main topics of our study, which focused on EGF and wound healing overall. To improve patient outcomes and enhance the efficacy of wound healing, particularly in aesthetic and reconstructive surgery, this bibliometric analysis emphasizes the importance of ongoing research and collaboration in this field.Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor Regarding: \"Vertical Superior Vector Suspension of the Anterior Mobile Face with the V Plication Facelift: A Volumization and Lifting Technique\".","authors":"Philippe Bellity, Lolita Pechevy, Raphael Carloni","doi":"10.1007/s00266-025-04818-8","DOIUrl":"https://doi.org/10.1007/s00266-025-04818-8","url":null,"abstract":"","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arif Yılmaz, Bilge Kağan Yılmaz, Çiğdem Karaca, Necmettin Karasu
{"title":"Investigation of the Effect of Preconditioning with Ultrasound on Fat Graft Survival.","authors":"Arif Yılmaz, Bilge Kağan Yılmaz, Çiğdem Karaca, Necmettin Karasu","doi":"10.1007/s00266-025-04771-6","DOIUrl":"https://doi.org/10.1007/s00266-025-04771-6","url":null,"abstract":"<p><strong>Background: </strong>The use of fat grafts in plastic, reconstructive, and aesthetic surgery has been increasing. Although fat grafting has many advantages, there is limited evidence regarding its survival rates. Current studies focus on improving fat graft survival rates. This study aimed to evaluate the effect of therapeutic ultrasound (TERUS) application on fat graft survival.</p><p><strong>Methods: </strong>The study involved 42 adult male Wistar Albino rats, which were randomly divided into seven groups of six rats each: Group 1 served as the control group and received only fat grafting; Group 2 received preoperative daily TERUS for one week, followed by fat grafting; Group 3 underwent preoperative daily massage for one week, followed by fat grafting; Group 4 received preoperative daily TERUS for one week, followed by fat grafting and postoperative daily TERUS for one week; Group 5 underwent preoperative daily massage for one week, followed by fat grafting and postoperative daily massage for one week; Group 6 received postoperative daily TERUS for one week; and Group 7 received postoperative daily massage for one week. After volume and weight measurements, immunohistochemical evaluation was conducted using perilipin and PECAM-1. Apoptosis was assessed using the TUNEL method.</p><p><strong>Results: </strong>No statistically significant differences were observed in the macroscopic measurements. While TERUS increased the vascularization of fat grafts, it did not improve survival rates. The mean fat graft survival rate in the preoperative-postoperative massage group (Group 5) was statistically significantly higher than in the other groups.</p><p><strong>Conclusions: </strong>The findings of this study suggest that the massage effect of TERUS, independent of ultrasonic energy, may be beneficial for fat graft survival. Although TERUS increases the vascularity of fat grafts, it does not improve fat graft survival rates.</p><p><strong>No level assigned: </strong>This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mapping the Global Research Landscape: A Bibliometric Analysis of Clinical Trials on Skin Aging-Trends, Innovations, and Research Gaps.","authors":"Sa'ed H Zyoud, Tauseef Ahmad, Samah W Al-Jabi","doi":"10.1007/s00266-025-04823-x","DOIUrl":"https://doi.org/10.1007/s00266-025-04823-x","url":null,"abstract":"<p><p>Skin aging is a multifaceted biological process influenced by both intrinsic and extrinsic factors. It involves changes at the tissue, cellular, and molecular levels. Recently, clinical trials have provided growing evidence across various aspects of skin aging. This study provides a thorough analysis of scientific publications on clinical trials related to skin aging. It includes publications indexed in the Scopus database between 2005 and 2024, retrieved using a wide array of pertinent keywords. Following this, network analysis and visualization were performed with VOSviewer (v. 1.6.20) to map research trends and pinpoint emerging research hotspots. From 2005 to 2024, 550 publications investigated the relationship between clinical trials and skin aging. Over the past two decades, the number of publications in this field has increased significantly (R<sup>2</sup> = 0.9346; p < 0.001), from seven in 2005 to 93 in 2024. This growth can be divided into two phases: a gradual increase from 2005 to 2015, followed by a period of rapid expansion from 2016 to 2024. The United States leads with 128 publications, representing 23.27% of the total. South Korea ranks second with 81 publications (14.73%), China ranks third with 54 publications (9.82%), and Italy ranks fourth with 49 publications (8.91%). Recent studies have concentrated on several key areas, including \"topical anti-aging treatments and nutraceuticals,\" \"patient safety and satisfaction in laser and light-based therapies, with a focus on adverse effects and clinical trial findings,\" and \"clinical trials examining oral supplements for skin wrinkling and aging.\" This analysis underscores the pressing need for ongoing research and collaboration to enhance patient outcomes and the efficacy of anti-aging treatments, especially those involving topical treatments, nutraceuticals, and oral supplements.Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case Report on Madelung's Disease.","authors":"Ting Wu, Sinan Yan, Shuangba He","doi":"10.1007/s00266-025-04783-2","DOIUrl":"https://doi.org/10.1007/s00266-025-04783-2","url":null,"abstract":"","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary on \"Machine Learning, Deep Learning, Artificial Intelligence and Aesthetic Plastic Surgery: A Qualitative Systematic Review\" by Nogueira et al. (2025).","authors":"Hamidreza Zivarifar, Tahereh Ahrari-Roodi, Masoud Keikha","doi":"10.1007/s00266-025-04825-9","DOIUrl":"https://doi.org/10.1007/s00266-025-04825-9","url":null,"abstract":"<p><p>No Level Assigned This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed A Althobaiti, Muhammad Talha Maniya, Rakan H Alelyani, Sabeeh Khawar Farooqui, Abdulaziz Saud Aljuaid, Zainb Mohammed Alfarej, Ahmed Abdullah Almenhali, Fahad K Aljindan
{"title":"Tranexamic Acid for Postoperative Outcomes in Breast Plastic Surgery: A Systematic Review and Meta-analysis.","authors":"Mohammed A Althobaiti, Muhammad Talha Maniya, Rakan H Alelyani, Sabeeh Khawar Farooqui, Abdulaziz Saud Aljuaid, Zainb Mohammed Alfarej, Ahmed Abdullah Almenhali, Fahad K Aljindan","doi":"10.1007/s00266-025-04772-5","DOIUrl":"https://doi.org/10.1007/s00266-025-04772-5","url":null,"abstract":"<p><strong>Background and objectives: </strong>Tranexamic acid (TXA), a synthetic antifibrinolytic agent, offers considerable promise as a potential therapy to improve postoperative outcomes for patients undergoing breast surgery. However, its specific role in plastic breast surgery remains understudied. Hence, we aimed to evaluate its efficacy in cosmetic plastic breast surgery.</p><p><strong>Methods: </strong>An extensive literature search of electronic databases such as PubMed, Embase, and Cochrane CENTRAL was conducted from inception to October 2023. Quality assessment of the included studies was done using the Newcastle-Ottawa scale (NOS). The results of our analyses were presented as odds ratios (ORs) with 95% confidence intervals (CIs) and pooled using a random effects model. A p-value < 0.05 was considered significant in all cases.</p><p><strong>Results: </strong>A total of 8 studies, encompassing 2311 participants were included in our analysis. The pooled analysis demonstrates that TXA is associated with a significant improvement in hematoma formation (OR 0.37, 95% CI: 0.24-0.58; p < 0.0001). There was no significant improvement in seroma formation (OR 0.65, 95% CI: 0.33-1.27; p = 0.21), infection rate (OR 1.84, 95% CI: 0.49-6.94; p = 0.37) or partial loss of the nipple-areolar complex (OR 0.47, 95% CI: 0.12-1.82; p = 0.28).</p><p><strong>Conclusion: </strong>Tranexamic acid demonstrated considerable efficacy in improving postoperative outcomes for patients undergoing cosmetic and reconstructive breast surgeries.</p><p><strong>Level of evidence i: </strong>This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Eyebrow Design for Chinese Men Before Eyebrow Transplantation.","authors":"Hang Li, Jinqing Li, Shuao Xiao, Yong Pan","doi":"10.1007/s00266-025-04781-4","DOIUrl":"https://doi.org/10.1007/s00266-025-04781-4","url":null,"abstract":"<p><strong>Background: </strong>Currently, there is no standardized preoperative eyebrow design method specifically for eyebrow transplantation surgery in clinical practice. This paper introduces a model tailored for the Chinese male population, the \"five-point method\" which is based on existing eyebrow design techniques and aims to provide a basis for eyebrow shape design in eyebrow transplantation surgery.</p><p><strong>Methods: </strong>In a prospective study spanning two years (June 2020-May 2022), 21 patients who underwent the \"five-point method\" were included. Blind observers used the Global Aesthetic Improvement Scale (GAIS) to assess these patients and 33 others who had previously undergone conventional eyebrow transplantation. Additionally, patients self-evaluated using the FACE-Q scale preoperatively and six months postoperatively, analyzing changes in appearance, psychological, and social functioning.</p><p><strong>Results: </strong>The GAIS results indicated that 95.24% of patients treated with the \"five-point method\" were rated as \"greatly improved,\" \"much improved,\" or \"improved,\" significantly outperforming the 84.85% in conventional eyebrow transplantation. FACE-Q self-assessment results showed that, compared to preoperative conditions, most patients experienced improvements in appearance, aging, psychological, and social functioning.</p><p><strong>Conclusion: </strong>The \"five-point method\" is a standardized, effective preoperative eyebrow design method, superior to conventional surgery in terms of improvement. Additionally, patients who underwent the \"five-point method\" reported higher levels of self-satisfaction.</p><p><strong>Level of evidence iii: </strong>This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond the Brazilian Butt Lift: How to Objectively Measure Outcome.","authors":"Agostino Bruno, Matteo Cilluffo","doi":"10.1007/s00266-025-04744-9","DOIUrl":"https://doi.org/10.1007/s00266-025-04744-9","url":null,"abstract":"<p><strong>Background: </strong>The demand for gluteal augmentation, commonly known as Brazilian Butt Lift (BBL), has significantly increased, driven by evolving beauty standards. Despite its popularity, the procedure is associated with serious complications, including pulmonary fat embolism, due to the challenges of ensuring the correct injection plane. The development of ultrasound-guided fat grafting offers a potential solution, enhancing the safety and precision of the procedure.</p><p><strong>Objectives: </strong>To demonstrate the efficacy, safety, and superior aesthetic outcomes of ultrasound-guided gluteal lipofilling. This will be attempted by using specialized software for processing photos and digital images, such as Photoshop, in order to obtain values through measurements that allow for an objective comparison of images of patients who have undergone gluteal lipofilling with and without ultrasound guidance.</p><p><strong>Methods: </strong>A retrospective study was conducted on 200 patients who underwent BBL, divided into two groups: 100 patients with traditional, non-ultrasound-guided fat grafting, and 100 with ultrasound-guided fat grafting. The study used preoperative and postoperative photographs analyzed through two-dimensional software to measure changes in gluteal volume. Measurements focused on the distances between fixed anatomical landmarks on the gluteal and thigh regions. Outcomes from the two groups were compared to evaluate the effectiveness and safety of the ultrasound-guided technique.</p><p><strong>Results: </strong>The ultrasound-guided procedure showed improved distribution of adipose tissue in the gluteal region compared to the non-ultrasound-guided technique, with fewer complications reported. The data analysis shows that, for lateral projection images, the average percentage variation was 2.04% for non-ultrasound-guided procedures and 2.81% for ultrasound-guided lipofilling.</p><p><strong>Conclusion: </strong>The integration of ultrasound technology in BBL procedures allows for real-time visualization of the cannula tip, reducing the risk of intramuscular injections and improving fat distribution. Although minimal, the difference in efficacy between the two techniques is evident. Furthermore, the ultrasound-guided technique has been associated with a lower complication rate according to numerous studies and is therefore preferable. Comparison of Techniques: The study compares the efficacy of ultrasound-guided and non-ultrasound-guided procedures, analyzing data from 200 patients.</p><p><strong>Methods: </strong>The results were obtained using software for processing photos and images. Efficacy Outcomes: The ultrasound-guided procedure showed a slight but measurable improvement in percentage variation over the non-ultrasound-guided method.</p><p><strong>Clinical recommendations: </strong>Based on the findings, the ultrasound-guided method is recommended due to its demonstrated safety benefits and reliable results.","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}