Raquel Nogueira, Diego L Lima, Pedro Salomao Piccinini
{"title":"Reply to Commentary on \"Machine Learning, Deep Learning, Artificial Intelligence and Aesthetic Plastic Surgery: A Qualitative Systematic Review\".","authors":"Raquel Nogueira, Diego L Lima, Pedro Salomao Piccinini","doi":"10.1007/s00266-025-04938-1","DOIUrl":"10.1007/s00266-025-04938-1","url":null,"abstract":"","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eqram Rahman, William Richard Webb, Parinitha Rao, Shabnam Sadeghi-Esfahlani, Nanze Yu, Patricia E Garcia, Sotirios Ioannidis, Karim Sayed, Wolfgang G Philipp-Dormston, Ada R T Almeida, Woffles T L Wu, Greg J Goodman, Jean D A Carruthers
{"title":"Frontalis Only Contracts in One Direction: AI-Quantum Elasticity and Resistance Gradient Reveals True Nature of Forehead Muscle Movement.","authors":"Eqram Rahman, William Richard Webb, Parinitha Rao, Shabnam Sadeghi-Esfahlani, Nanze Yu, Patricia E Garcia, Sotirios Ioannidis, Karim Sayed, Wolfgang G Philipp-Dormston, Ada R T Almeida, Woffles T L Wu, Greg J Goodman, Jean D A Carruthers","doi":"10.1007/s00266-025-04924-7","DOIUrl":"https://doi.org/10.1007/s00266-025-04924-7","url":null,"abstract":"<p><strong>Background: </strong>The biomechanics of frontalis muscle contraction and its interaction with skin remain contentious, particularly the debated bidirectional movement theory. This study introduces the quantum elasticity and resistance gradient (QERG) model to explain observed skin dynamics during frontalis contraction using elastic resistance principles.</p><p><strong>Methods: </strong>An AI-driven biomechanical model incorporating deep learning frameworks (TensorFlow, PyTorch) was developed to simulate skin deformation and muscle forces during frontalis contraction. The model was trained using 3D facial scans from a diverse cohort of 600 subjects, representing various ethnicities, genders, and ages. Resistance gradients and wrinkle formation were calculated using finite element analysis, and machine learning (random forest, deep neural networks) was employed to predict skin behaviour.</p><p><strong>Results: </strong>Cranial displacement averaged 6.9 mm across all subjects, with younger individuals (18-30 years) showing higher displacement than older individuals (50-65 years). Ethnic differences in displacement and wrinkle formation were observed, with Caucasians exhibiting greater displacement (7.3 mm) compared to African Americans and Asians (6.0 mm and 5.8 mm). The QERG model predicted skin folding at an average threshold of 41.2 mm above the eyebrows, with variations linked to ethnicity, age, and gender. AI models achieved high accuracy (R<sup>2</sup> = 0.96), validating the model's predictive power.</p><p><strong>Conclusion: </strong>The QERG model confirms that frontalis muscle contraction is unidirectional, with skin folding attributed to elastic resistance rather than opposing forces. These findings challenge previous theories of bidirectional contraction and have implications for aesthetic treatments.</p><p><strong>Level of evidence iii: </strong>This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bleeding Risk in Post-bariatric Abdominoplasties: A Large Cohort Study.","authors":"Nicole Garcia, Ishith Seth, Gianluca Marcaccini, Warren M Rozen, Roberto Cuomo","doi":"10.1007/s00266-025-04887-9","DOIUrl":"https://doi.org/10.1007/s00266-025-04887-9","url":null,"abstract":"<p><strong>Background: </strong>Post-bariatric abdominoplasty is a standard procedure to improve body contour and quality of life following massive weight loss. However, perioperative bleeding remains a concern, particularly in the context of thromboprophylaxis and pre-existing comorbidities. This study investigates the risk factors for bleeding, including hypertension and bariatric surgery type, in patients undergoing abdominoplasty post-bariatric surgery.</p><p><strong>Methods: </strong>Patient data were retrospectively collected from a tertiary centre in Italy. Patient demographics, comorbidities, bariatric surgery type, and thromboprophylaxis use were analysed. Univariable and multivariable regression analyses identified significant predictors of bleeding. Risk ratios (RR) were calculated for bleeding outcomes based on bariatric surgery type and patient variables.</p><p><strong>Results: </strong>A total of 201 patients who underwent abdominoplasty following bariatric surgery were included in the analysis. The cohort had a median age of 44 years, with 71% female (142/201). Hypertension was significantly associated with bleeding risk (β = 0.1, p = 0.047; RR = 2.5, 95% CI: 1.02-6.01, p = 0.045). Among bariatric procedures, gastric banding conferred the highest bleeding risk compared to mini-gastric bypass (RR = 6.8, 95% CI: 2.09-21.8, p = 0.001). Sleeve gastrectomy also showed a higher bleeding risk than mini-gastric bypass (RR = 3.3, 95% CI: 1.24-8.5, p = 0.016).</p><p><strong>Conclusion: </strong>Hypertension emerged as an independent risk factor for bleeding in post-bariatric abdominoplasty, increasing risk by more than twofold. Additionally, bariatric surgery type influenced outcomes, with gastric banding and sleeve gastrectomy associated with higher bleeding risk compared to mini-gastric bypass. These findings highlight the importance of preoperative optimisation and surgical planning to mitigate bleeding complications.</p><p><strong>Level of evidence v: </strong>This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sile Shen, Siwei Qu, Mingdian Wang, Kai Ji, Yang Zhou, Jian Chen, Chengyuan Wang
{"title":"Efficacy and Safety of Collagen Filler for Intradermal Injection: A Randomized Prospective Controlled Multicenter Study.","authors":"Sile Shen, Siwei Qu, Mingdian Wang, Kai Ji, Yang Zhou, Jian Chen, Chengyuan Wang","doi":"10.1007/s00266-025-04960-3","DOIUrl":"https://doi.org/10.1007/s00266-025-04960-3","url":null,"abstract":"<p><strong>Background: </strong>With the increasing demand for minimally invasive aesthetic procedures, intradermal injection has emerged as a promising method to improve skin condition. However, there is a lack of robust clinical evidence supporting the efficacy and safety of intradermal collagen injections.</p><p><strong>Objective: </strong>The purpose of this study is to investigate the improvement of facial skin and safety of collagen intradermal injections.</p><p><strong>Methods: </strong>This prospective, multicenter, randomized, assessor-masked clinical trial enrolled 480 subjects aged 18-65 seeking facial skin enhancement. Subjects were randomized into treatment (n = 240) and control (n = 240) groups. The treatment group received three sessions of intradermal collagen injections at four-week intervals. Assessments included the Global Aesthetic Improvement Scale (GAIS), composite scale for skin dryness and dull complexion, Allergan Fine Lines Scale (AFLS), Allergan Skin Roughness Scale (ASRS), skin hydration, elasticity, and safety evaluations.</p><p><strong>Results: </strong>The GAIS and skin improvement rates showed significant differences between groups (P < 0.0001), with the treatment group demonstrating superior efficacy. No significant differences were observed in skin hydration and elasticity (P > 0.05). The treatment group exhibited higher improvement rates in GAIS, dull complexion, fine lines, and skin roughness at 4 weeks post-final injection compared to the control group. No severe treatment-emergent adverse events related to the trial device occurred.</p><p><strong>Conclusion: </strong>Intradermal collagen injections significantly enhance skin texture and demonstrate safety and reliability in clinical settings, offering a favorable risk-benefit ratio for appropriate candidates.</p><p><strong>Level of evidence i: </strong>This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nitzan Kenig, Javier Monton Echeverria, Aina Muntaner Vives
{"title":"Evaluating Surgical Results in Breast Cancer with Artificial Intelligence.","authors":"Nitzan Kenig, Javier Monton Echeverria, Aina Muntaner Vives","doi":"10.1007/s00266-025-04915-8","DOIUrl":"https://doi.org/10.1007/s00266-025-04915-8","url":null,"abstract":"<p><strong>Introduction: </strong>Artificial intelligence (AI) is rapidly transforming healthcare, with increasing applications in surgical evaluation. In breast cancer surgery, achieving aesthetic symmetry is essential for patient satisfaction and emotional well-being. While human evaluation remains fundamental, AI-driven symmetry assessment promises objective alternatives. This study evaluates the performance of publicly available AI models in breast symmetry assessment and compares them with Pyolo8, a custom AI model developed by the authors. Additionally, the study explores the potential emotional impact and ethical considerations of AI-generated assessments in postoperative breast cancer patients.</p><p><strong>Methods: </strong>Sixty-eight patients who underwent breast reconstruction were evaluated with the use of publicly available AI models and contrasted with an AI model developed by the authors named Pyolo8. All results were evaluated by human observers.</p><p><strong>Results: </strong>ChatGPT 4o and Pyolo8 AI models showed statistically significant moderate to strong positive correlation for postoperative assessment when compared to human observers. Direct interaction between AI models and patients was censored due to concerns of misinterpretation.</p><p><strong>Conclusions: </strong>Both ChatGPT and Pyolo8 showed moderate to strong correlation with humans, but ChatGPT demonstrated superior communication skills. However, AI systems may lack the subtlety and empathy required for direct patient interactions, as vulnerable postoperative patients receiving an AI-generated symmetry assessment without appropriate clinical context may experience emotional distress or misinterpret the results. Human oversight and empathetic communication remain essential to ensure quality care while AI is increasingly integrated into medicine.</p><p><strong>Level of evidence iv: </strong>This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to Editor Regarding: 'Upper Eyelid Blepharoptosis Correction Performed Under the Operating Microscope'.","authors":"Chao-Hsin Huang, Shu-Hung Huang","doi":"10.1007/s00266-025-04979-6","DOIUrl":"https://doi.org/10.1007/s00266-025-04979-6","url":null,"abstract":"","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Restoring Abdominal Integrity in Necrotizing Fasciitis Following Liposuction: A Case Report.","authors":"Qian Wu, Guiwen Zhou, Minliang Chen","doi":"10.1007/s00266-025-04994-7","DOIUrl":"https://doi.org/10.1007/s00266-025-04994-7","url":null,"abstract":"<p><p>Level of Evidence IV This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor: Montemurro, P., Gupta, T. Does the Surgeon's Handedness Affect the Complications Rate in the Inframammary Approach Breast Augmentation? Aesth Plast Surg 49, 1271-1275 (March 2025).","authors":"Ted S Eisenberg, Julianne Pilla, George Chapa","doi":"10.1007/s00266-025-04999-2","DOIUrl":"https://doi.org/10.1007/s00266-025-04999-2","url":null,"abstract":"","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aurora Almadori, Esther Hansen, Peter Butler, Marzia Salgarello
{"title":"A Novel Approach to Female Genital Mutilation Reconstruction with Fat Grafting and Adipose Stem Cell Therapies: A Minimally Invasive Solution with a Potential Impact on Millions of Women Worldwide.","authors":"Aurora Almadori, Esther Hansen, Peter Butler, Marzia Salgarello","doi":"10.1007/s00266-025-04895-9","DOIUrl":"https://doi.org/10.1007/s00266-025-04895-9","url":null,"abstract":"<p><strong>Background: </strong>FGM is an issue of increasing concern also in countries where it is not traditionally practiced. Vulvar scarring is the most common long-term effect associated with FGM, representing one of the main unmet issues in FGM women's health. Regenerative therapies based on the use of adipose-derived stem cells are considered the standard of care for ameliorating scarring and fibrosis. This study aimed to explore the potential of fat grafting in the treatment of post-FGM vulvar scars.</p><p><strong>Methods: </strong>Thirteen FGM survivors with vulvar scars underwent autologous fat grafting and were assessed using the Vulvar architecture severity scale (VASS), Female genital self-image scale (FGSIS), Female sexual function index (FSFI), and Hospital anxiety and depression scale (HADS).</p><p><strong>Results: </strong>At an average follow-up of 12.23 months (± 3.03), clinical results (VASS) showed a significant improvement in all vulvar aesthetic units treated with FG (p < 0.001). Patients reported improvements in genital-related self-image (FGSIS) (p = 0.001), sexual function (FSFI) (p = 0.019), and psychological well-being (HADS) (p = 0.002).</p><p><strong>Conclusions: </strong>Fat grafting ameliorates FGM-related vulvar scars and improves volumetric contouring of vulvar aesthetic units, with a positive effect on women's quality of life. This minimally invasive intervention has far-reaching implications, providing a cost-effective solution accessible even in low-resource settings to potentially improve the overall well-being of millions of women living worldwide with a form of FGM. The results of this study warrant further testing in future clinical trials.</p><p><strong>Level of evidence iv: </strong>This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ghazal Ghochani, Amirhossein Aghajani, Mohammad Taher Rajabi, Amin Zand, Mehdi Yaseri, Seyed Mohsen Rafizadeh
{"title":"Comparison of Two Botulinum Neurotoxin Type A Preparations (Masport and Dysport) for Upper Face Rhytides: A Randomized Clinical Trial.","authors":"Ghazal Ghochani, Amirhossein Aghajani, Mohammad Taher Rajabi, Amin Zand, Mehdi Yaseri, Seyed Mohsen Rafizadeh","doi":"10.1007/s00266-025-04929-2","DOIUrl":"https://doi.org/10.1007/s00266-025-04929-2","url":null,"abstract":"<p><strong>Background: </strong>Botulinum neurotoxin type A has played a key role in the treatment of facial rhytides. We aimed to compare the safety and effectiveness of Masport and Dysport as botulinum toxin type A preparations in the treatment of upper face rhytides.</p><p><strong>Methods: </strong>A double-blind randomized, clinical trial was conducted on adults with at least mild severity (scale 1) for lateral canthal (crow's feet), glabellar, and frontal lines at maximum contraction positions (dynamic status), regardless of their static scales (rest position). Participants were randomly assigned to receive either Masport or Dysport. Rhytides in each area were scaled at baseline and at post-injection weeks 2, 8, 12, and 16. Self-satisfaction were assessed at follow-ups.</p><p><strong>Results: </strong>For both groups, a decrease in dynamic rhytides was observed at week 2 compared to baseline (all Ps < 0.05). Although dynamic rhytides increased again in subsequent follow-ups, they remained significantly lower than baseline levels until week 12 (all Ps < 0.05). By week 16, no differences were observed compared to baseline (all Ps > 0.05). While at week 2, both dynamic and static scales were higher in the Masport group (all Ps < 0.05), this difference did not persist for most of them at weeks 12 and 16. Satisfaction scores were similar between the groups throughout all follow-ups (all Ps > 0.05).</p><p><strong>Conclusion: </strong>The onset and duration of action for Masport and Dysport are similar in the treatment of upper face rhytides at equal doses. While Dysport may initially show a stronger effect than Masport in treating upper face rhytides, this advantage does not persist in the long term.</p><p><strong>Level of evidence i: </strong>This journal requires that authors assign a level of evidence to each article. For a full description of these evidence-based medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}