Journal of biological standardization最新文献_第6页

Studies on yellow fever vaccine II—stability of the reconstituted product 黄热病疫苗的研究ii——重组产物的稳定性

Journal of biological standardization Pub Date : 1988-01-01 DOI: 10.1016/0092-1157(88)90033-9

Oscar de Souza Lopes , Suely S.D. de Almeida Guimarães , Ricardo de Carvalho

引用次数: 6

Dépistage de la leucose bovine enzootique par le test elisa appliqué au lactoserum concentré de tank 通过应用于浓缩罐乳清的ELISA试验检测酶促牛白血病

Journal of biological standardization Pub Date : 1988-01-01 DOI: 10.1016/0092-1157(88)90036-4

P. Prevost , M. Eloit , B. Toma

引用次数: 4

WHO international reference reagents for human proinsulin and human insulin C-peptide 世卫组织人胰岛素原和人胰岛素c肽国际参考试剂

Journal of biological standardization Pub Date : 1988-01-01 DOI: 10.1016/0092-1157(88)90005-4

A.F. Bristow , R.E.Gaines Das

引用次数: 27

Determination of the epinephrine-refractory hypoglycaemic activity of whole-cell pertussis vaccine in mice 小鼠全细胞百日咳疫苗肾上腺素难治性降糖活性的测定

Journal of biological standardization Pub Date : 1988-01-01 DOI: 10.1016/0092-1157(88)90011-X

Y. Horiuchi , T. Iida

引用次数: 1

Interference between strains in live virus vaccines II: combined vaccination with varicella and measles-mumps-rubella vaccine 活病毒疫苗株间的干扰II:水痘和麻疹-腮腺炎-风疹联合疫苗接种

Journal of biological standardization Pub Date : 1988-01-01 DOI: 10.1016/0092-1157(88)90015-7

Rosemarie Berger , Max Just

引用次数: 32

The production of mycobacterial antigens by homogeneous culture in a fermentor 在发酵罐中通过同质培养生产分枝杆菌抗原

Journal of biological standardization Pub Date : 1988-01-01 DOI: 10.1016/0092-1157(88)90013-3

Jean Nyabenda , Erwin Bautens , Martine Borremans , Roger Verhofstadt , Maurice Weckx , André Marchal

引用次数: 4

World Health Organization International Standards for highly purified human, porcine and bovine insulins 世界卫生组织高纯度人、猪和牛胰岛素国际标准

Journal of biological standardization Pub Date : 1988-01-01 DOI: 10.1016/0092-1157(88)90004-2

A.F. Bristow , R.E.Gaines Das , D.R. Bangham

{"title":"World Health Organization International Standards for highly purified human, porcine and bovine insulins","authors":"A.F. Bristow , R.E.Gaines Das , D.R. Bangham","doi":"10.1016/0092-1157(88)90004-2","DOIUrl":"10.1016/0092-1157(88)90004-2","url":null,"abstract":"<div><p>The 4th International Standard (IS) for Insulin, established in 1958, consists of a mixture of relatively impure bovine and porcine insulins and is not suitable as a standard for the assay of highly purified single-species insulins presently used in the treatment of diabetes. Preparations of human, bovine and porcine crystalline insulins, representative of current highly purified therapeutic insulins, have now been studied in an international collaborative study carried out by twenty-three laboratories in fifteen countries. In the collaborative study described here, each of the three preparations was found to be suitable for use as a standard for insulin for bioassay and each was established by WHO in 1986 as an international standard. The 4th IS of Insulin bovine/porcine (code numbered 58/6) has been discontinued. Insulin preparations should now be calibrated in terms of International Units defined by the standard for the appropriate species: the International Standard for Insulin, Human, the International Standard for Insulin, Bovine, or the International Standard for Insulin, Porcine.</p></div>","PeriodicalId":75991,"journal":{"name":"Journal of biological standardization","volume":"16 3","pages":"Pages 165-178"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0092-1157(88)90004-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14181332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

The stability and immunogenicity of a dispersed-grown freeze-dried pasteur BCG vaccine 分散生长的冻干巴斯德卡介苗的稳定性和免疫原性

Journal of biological standardization Pub Date : 1988-01-01 DOI: 10.1016/0092-1157(88)90025-X

M. Gheorghiu , P.H. Lagrange , C. Fillastre

{"title":"The stability and immunogenicity of a dispersed-grown freeze-dried pasteur BCG vaccine","authors":"M. Gheorghiu , P.H. Lagrange , C. Fillastre","doi":"10.1016/0092-1157(88)90025-X","DOIUrl":"10.1016/0092-1157(88)90025-X","url":null,"abstract":"<div><p>The level of antituberculous immunity seems to be related to the number of memory T cells induced. This may vary as a function of the multiplication and persistence of BCG in host tissues. The most important requirements for a BCG vaccine are, therefore, the immunogenicity of the strain, the high proportion of live to dead bacilli, and adequate dispersion and low levels of soluble antigens. The surface-grown Pasteur BCG vaccine contains a very high proportion of bacilli killed by ball-milling and freeze-drying. It also contains clumps and soluble antigens, all factors influencing cell-mediated immune processes and viability control. Therefore, several batches of vaccine were prepared on an industrial scale using one of the most immunogenic strains (French 1173 P2) and grown as dispersed bacilli by a modified cell type culture method. This method provided fully viable, well-dispersed vaccines which have a viability and heat stability superior to that of the classical surface-grown BCG. The immunogenicity was checked by multiplication and persistence in mouse organs and the skin reactivity and tuberculin hypersensitivity in guinea-pigs showed results comparable to those obtained with classical vaccine. Small-scale tests in children showed superior immunogenicity of the dispersed as opposed to the classical vaccine and there was no suppurative adenitis.</p></div>","PeriodicalId":75991,"journal":{"name":"Journal of biological standardization","volume":"16 1","pages":"Pages 15-18, IN1, 19-26"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0092-1157(88)90025-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14477780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 71

Development of a mouse model to estimate the potency of the diphtheria toxoid component of diphtheria-tetanus and diphtheria-tetanus-pertussis vaccines 开发小鼠模型以估计白喉-破伤风和白喉-破伤风-百日咳疫苗中白喉类毒素成分的效力

Journal of biological standardization Pub Date : 1988-01-01 DOI: 10.1016/0092-1157(88)90001-7

S.C. Maheshwari , Suniti B. Sharma , Subhash Ahuja , S.N. Saxena

引用次数: 7

Interference between strains in live virus vaccines I: combined vaccination with measles, mumps and rubella vaccine 活病毒疫苗株间的干扰:与麻疹、腮腺炎和风疹疫苗联合接种

Journal of biological standardization Pub Date : 1988-01-01 DOI: 10.1016/0092-1157(88)90014-5

Rosemarie Berger , Max Just , Reinhard Glück

引用次数: 28