Chan Wu, Shenshen Yan, Yining Dai, Hong Du, Yan Zhou, Qin Long, Xianshi Meng, Rongping Dai, Haiying Zhou
{"title":"The Significance of Retinal Arterial Anastomosis in the New Classification System of Prepapillary Vascular Loops","authors":"Chan Wu, Shenshen Yan, Yining Dai, Hong Du, Yan Zhou, Qin Long, Xianshi Meng, Rongping Dai, Haiying Zhou","doi":"10.1016/j.ajo.2025.06.030","DOIUrl":"https://doi.org/10.1016/j.ajo.2025.06.030","url":null,"abstract":"<ce:bold>:</ce:bold> To analyze the ophthalmic characteristics of congenital prepapillary vascular loops (PVL), propose the significance of retinal arterial anastomosis and propose a new classification of PVL.","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"3 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ling Lee, Laura De Angelis, Erica Barclay, Nina Tahhan, Kathryn Saunders, Emma McConnell, Neema Ghorbani- Mojarrad, Annegret Dahlmann-Noor, Anton Jaselsky, Nicolas Leveziel, Dominique Bremond-Gignac, Serge Resnikoff, Timothy R Fricke
{"title":"Factors affecting the lifetime cost of myopia and the impact of active myopia treatments in Europe","authors":"Ling Lee, Laura De Angelis, Erica Barclay, Nina Tahhan, Kathryn Saunders, Emma McConnell, Neema Ghorbani- Mojarrad, Annegret Dahlmann-Noor, Anton Jaselsky, Nicolas Leveziel, Dominique Bremond-Gignac, Serge Resnikoff, Timothy R Fricke","doi":"10.1016/j.ajo.2025.06.034","DOIUrl":"https://doi.org/10.1016/j.ajo.2025.06.034","url":null,"abstract":"<ce:bold>:</ce:bold> There are an increasing number of effective myopia control options available, however their financial impacts are unclear. We estimated lifetime costs of myopia under five scenarios in France and the United Kingdom (UK): traditional myopia management (single vision correction), low-dose atropine, anti-myopia spectacles, anti-myopia soft contact lenses and orthokeratology.","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"45 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shayan Massoumi BS, John Stoffer MD, Brenton T. Bicknell BS, Josephine M. Rudd Zhong Manis BS, Haley Chishom BS, Yejin Heo BS, Lance Dzubinski BS, Alvina Liang BS, Taylor L. Aaserud BS, Thanushri Srikantha BS, Robert Tauscher MD, Tatyana Milman MD, Maura Di Nicola MD, Basil K. Williams Jr. MD
{"title":"Ocular Oncologists and Ophthalmic Pathologists in Academic Ophthalmology: A Descriptive Analysis of the Current Workforce in the United States","authors":"Shayan Massoumi BS, John Stoffer MD, Brenton T. Bicknell BS, Josephine M. Rudd Zhong Manis BS, Haley Chishom BS, Yejin Heo BS, Lance Dzubinski BS, Alvina Liang BS, Taylor L. Aaserud BS, Thanushri Srikantha BS, Robert Tauscher MD, Tatyana Milman MD, Maura Di Nicola MD, Basil K. Williams Jr. MD","doi":"10.1016/j.ajo.2025.06.022","DOIUrl":"https://doi.org/10.1016/j.ajo.2025.06.022","url":null,"abstract":"To characterize the academic profiles, leadership roles, research productivity, and gender disparities of ocular oncologists and ophthalmic pathologists (OOPs) and compare them to all other ophthalmologists (AOOs).","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"16 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadia J. Abbass MA, Kevin C. Allan MD PhD, Katherine E. Talcott MD, Rishi P. Singh MD
{"title":"Reply to Comment on The Effect of Semaglutide and GLP-1 RAs on Risk of Nonarteritic Anterior Ischemic Optic Neuropathy","authors":"Nadia J. Abbass MA, Kevin C. Allan MD PhD, Katherine E. Talcott MD, Rishi P. Singh MD","doi":"10.1016/j.ajo.2025.06.025","DOIUrl":"https://doi.org/10.1016/j.ajo.2025.06.025","url":null,"abstract":"","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"7 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alan Y. Hsu, Chun-Ju Lin, Yi-Ching Shao, Yi-Yu Tsai, Yu-Hsun Wang, James Cheng-Chung Wei
{"title":"Comment on: The Effect of Semaglutide and GLP-1 RAs on Risk of Nonarteritic Anterior Ischemic Optic Neuropathy","authors":"Alan Y. Hsu, Chun-Ju Lin, Yi-Ching Shao, Yi-Yu Tsai, Yu-Hsun Wang, James Cheng-Chung Wei","doi":"10.1016/j.ajo.2025.05.053","DOIUrl":"https://doi.org/10.1016/j.ajo.2025.05.053","url":null,"abstract":"","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"147 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Two Different Extraocular Muscle Suturing techniques for Strabismus Surgery","authors":"Tiantian Zhou, Wei Guo, Xiaoqi Zhu, Yu Jing, Qing Shao, Shiya Shen, Xin Chen, Zhenhua Leng, Bin Liu, Shihua Zhang, Wanwen Xu, Hu Liu, Hui Zhu","doi":"10.1016/j.ajo.2025.06.019","DOIUrl":"https://doi.org/10.1016/j.ajo.2025.06.019","url":null,"abstract":"To compare the surgical outcomes after bilateral medial rectus recession (BMR) or bilateral lateral rectus recession (BLR) performed with the three-point fixation (3PF) vs. two-point fixation (2PF) suturing techniques.","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"25 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perceived Discrimination, Hypervigilance, and Visual Disabilities Among United States Adults: An Analysis of National Survey Data.","authors":"Patrick Akarapimand,John C Lin,Fasika Woreta","doi":"10.1016/j.ajo.2025.06.023","DOIUrl":"https://doi.org/10.1016/j.ajo.2025.06.023","url":null,"abstract":"OBJECTIVETo investigate the association between visual disability and discrimination.DESIGNCross-sectional study.PARTICIPANTSWe employed data from the 2023 National Health Interview Survey (NHIS), including only US adult participants who responded to both the NHIS modules on visual disability and discrimination.METHODSVisual disability was defined as any reported difficulty with seeing even when wearing glasses or contact lenses. Adjusted Wald tests were performed to compare discrimination and hypervigilance between people with and without visual disabilities. Multiple ordinal regression models were employed to assess the associations between visual disability and Everyday Discrimination Scale (EDS) or Heightened Vigilance Scale (HVS), adjusting for age, sex, race/ethnicity, household income, education level, and the number of chronic conditions such as arthritis, cancer, chronic obstructive pulmonary disease, asthma, diabetes, and hypertension. Subgroup analyses across covariates were performed.MAIN OUTCOMES MEASURESDiscrimination was measured through two validated tools: the EDS, assessing the frequency of unfair treatment, and the HVS, measuring how often individuals anticipate or prepare for discrimination.RESULTS28,615 adults were included in this study. 54.3% were female, 33.6% identified as from racial or ethnic minoritized backgrounds, and 19.6% reported having visual disabilities. The mean EDS score for people with visual disabilities was significantly higher than for those without disabilities (3.28 vs 2.30, p<0.001), as well as the mean HVS score (4.12 vs 3.19, p<0.001). In multiple ordinal regression, visual disability was significantly associated with higher scores on the EDS (adjusted OR: 1.74, 95% CI: 1.62-1.87) and higher scores on the HVS (adjusted OR: 1.61, 95% CI: 1.51-1.72). This result was replicated across age and sex subgroup analyses.CONCLUSIONSPeople with visual disabilities reported more frequent discrimination and heightened vigilance. This underscores the urgent need for coordinated efforts across multiple sectors, such as healthcare, education, employment, and transportation, to address the discrimination faced by people with visual disabilities.","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"30 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H John Shammas,Maya C Shammas,Sam Multack,Ganesha Rom Kandavel,Justin Dredge,Robert Melendez,Brad Hall
{"title":"PROSPECTIVE EVALUATION OF A NEW IOL POWER FORMULA IN EYES MEASURED BY SUM-OF-SEGMENTS BIOMETRY.","authors":"H John Shammas,Maya C Shammas,Sam Multack,Ganesha Rom Kandavel,Justin Dredge,Robert Melendez,Brad Hall","doi":"10.1016/j.ajo.2025.06.015","DOIUrl":"https://doi.org/10.1016/j.ajo.2025.06.015","url":null,"abstract":"PURPOSETo evaluate the clinical outcomes from cataract surgery in eyes measured with sum-of-segments (SOS) biometry using the new Barrett True Axial Length (BTAL-SOS) formula and compare the potential results with the Barrett Universal II (BUII-SOS) formula.SETTINGFour private practice locations in Lynwood, CA, Encino, CA, Olympia Fields, IL, and Albuquerque, NM, USA.DESIGNProspective, multi-site, multi-surgeon, biometry accuracy study.METHODSThe expected residual refractions were calculated using the BTAL-SOS formula in 523 eyes after cataract surgery and compared to the potential results with the BUII-SOS formula. All eyes had a final visual acuity ≤0.20 LogMAR and ≤0.75 D of astigmatism.RESULTSMean prediction error (MPE) for the entire series was 0.00±0.27 D with BTAL-SOS compared to 0.00±0.28 D with BUII-SOS (p=0.06). In 79 eyes longer than 24.50 mm, MPE was - 0.02±0.24 D with BTAL-SOS vs -0.05±0.25 D with BUII-SOS (p=0.16) and in 73 eyes shorter than 22.50 mm, BTAL-SOS statistically outperformed BU II-SOS (p=0.03) with a MPE of -0.05±0.31 D vs 0.07±0.36 D. BTAL-SOS prediction error (PE) ≤0.50 D was 96.0% vs 84% in short eyes (AL≤22.00mm), 87.50% vs 81.25% in medium short eyes (AL>22.00mm, <22.50mm), 92.45% vs 93.26% in average eyes (AL 22.50-24.50mm), 92.68% vs 92.68% in medium long eyes (AL>24.50mm, <25.00mm) and 97.37% vs 94.74% in long eyes (AL≥25.00mm) when compared to BUII-SOS results.CONCLUSIONBTAL-SOS formula performed statistically better (p=0.03) than BUII-SOS in eyes shorter than 22.50 mm.","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"48 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S C M Kneepkens,L van Vught,J R Polling,C C W Klaver,J W L Tideman,J W M Beenakker
{"title":"A Novel MRI-Based Approach to Peripheral Refraction and Prediction of Myopia Progression.","authors":"S C M Kneepkens,L van Vught,J R Polling,C C W Klaver,J W L Tideman,J W M Beenakker","doi":"10.1016/j.ajo.2025.06.013","DOIUrl":"https://doi.org/10.1016/j.ajo.2025.06.013","url":null,"abstract":"PURPOSEOptical solutions that create peripheral myopic defocus in the presence of a clear central image have shown to be effective as myopia treatment. This study investigates whether peripheral refraction measured via MRI and ray tracing can predict myopia progression in children.METHODSA total of 1635 children from the Generation R Study, a population-based birth cohort in Rotterdam, the Netherlands, underwent T2 weighted MRI scanning at age 9 years. At both ages 9 and 14 years, ocular biometry, and cycloplegic autorefraction were assessed. Retinal curvature radii were computed from MRI segmentations using semi-automated, customized image processing algorithms. Individual peripheral refraction profiles were modelled through ray tracing. Horizontal and vertical peripheral refraction was analysed at 50-degrees eccentricity. Relative peripheral refraction (RPR) was calculated by subtracting peripheral refraction from central cycloplegic refraction. Yearly myopia progression was calculated and stratified into quantiles (∆AL), and the effect of RPR on the quantile outcomes was examined using ordinal regression analyses. Predictive performance of RPR on development of myopia was evaluated using ROC-analysis (fast vs slow progressors) and a logistic regression (incident myopia).RESULTSAt age 9 years, 207/1635 (13%) children had developed myopia. Myopic children had a significantly more hyperopic RPR compared to emmetropic children at all horizontal eccentricities (-1.8±1.8D vs. 0.2±2.1D; P<0.001) and vertical eccentricities (-1.0±1.9D vs. 0.8±2.2D; P<0.001). Higher vertical (OR: 1.08, CI: 1.02-1.14) and horizontal RPR (OR: 1.16, CI: 1.10-1.22) was associated with faster AL progression. Each diopter increase in vertical RPR (OR: 1.10, CI: 1.01-1.20) and horizontal RPR (OR: 1.23, CI: 1.13-1.35) was associated with an increased risk of incident myopia. ROC analysis indicated that RPR had a maximum predictive AUC of 0.77 for identifying fast progressors. Furthermore, MRI data revealed significant interindividual variations in retinal curvature (SD 1 mm), which resulted in clinically relevant peripheral refractive differences exceeding 8D among children with similar axial length and central SE, suggesting that standard defocus strategies may require individualization.CONCLUSIONSUsing this novel approach to calculate peripheral refraction, we provide evidence based on eye shape that peripheral hyperopic refractive error is more pronounced in myopic children and is strongly associated with myopia progression. The significant anatomical variability in retinal radii underscores the need for personalized treatment strategies, which may enhance the efficacy of optical interventions for myopia management.","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"600 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Pellegrini, Ginevra Giovanna Adamo, Antonio Cartabellotta, Maria Sole Zanella, Pietro Maria Talli, Francesco Nasini, Laura Sarti, Francesco Parmeggiani, Marco Mura
{"title":"Incidence, Risk Factors and Effect on Outcomes of Microcystic Macular Edema after Pars Plana Vitrectomy for Retinal Detachment","authors":"Marco Pellegrini, Ginevra Giovanna Adamo, Antonio Cartabellotta, Maria Sole Zanella, Pietro Maria Talli, Francesco Nasini, Laura Sarti, Francesco Parmeggiani, Marco Mura","doi":"10.1016/j.ajo.2025.06.016","DOIUrl":"https://doi.org/10.1016/j.ajo.2025.06.016","url":null,"abstract":"The purpose of this study was to evaluate the incidence, risk factors and clinical significance of microcystic macular edema (MME) after pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD).","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"51 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144305092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}