American Journal of Ophthalmology最新文献

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Corrigendum to Mo E, Chen Z, Feng K, et al. Accuracy of Modern Intraocular Lens Formulas in Highly Myopic Eyes Implanted With Plate-Haptic Intraocular Lenses. Am J Ophthalmol 2024;265:105-116. Mo E, Chen Z, Feng K, et al. 高度近视眼植入板层触觉眼内透镜的现代眼内透镜配方的准确性》的更正。Am J Ophthalmol 2024;265:105-116.
IF 4.1 1区 医学
American Journal of Ophthalmology Pub Date : 2024-09-28 DOI: 10.1016/j.ajo.2024.09.006
ER Mo , ZEXIN CHEN , KE FENG , ZEHUI ZHU , JIALIN XU , CHENYUAN ZHU , PINGJUN CHANG , JIN LI , YUN-E ZHAO
{"title":"Corrigendum to Mo E, Chen Z, Feng K, et al. Accuracy of Modern Intraocular Lens Formulas in Highly Myopic Eyes Implanted With Plate-Haptic Intraocular Lenses. Am J Ophthalmol 2024;265:105-116.","authors":"ER Mo , ZEXIN CHEN , KE FENG , ZEHUI ZHU , JIALIN XU , CHENYUAN ZHU , PINGJUN CHANG , JIN LI , YUN-E ZHAO","doi":"10.1016/j.ajo.2024.09.006","DOIUrl":"10.1016/j.ajo.2024.09.006","url":null,"abstract":"","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"268 ","pages":"Page 419"},"PeriodicalIF":4.1,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to Risk of Corneal Graft Rejection and Vaccination: A Matched Case-Control Study From a United States Integrated Health Care System Am J Ophthalmol 2024 Jul:263:133-140 角膜移植排斥风险与疫苗接种》的更正:美国综合医疗系统的匹配病例对照研究 Am J Ophthalmol 2024 Jul:263:133-140.
IF 4.1 1区 医学
American Journal of Ophthalmology Pub Date : 2024-09-28 DOI: 10.1016/j.ajo.2024.09.003
Jennifer H Ku , Afshan A Nanji , Julia E Tubert , Cynthia Joe , Divya Srikumaran , Kevin L Winthrop , Amanda E Brunton , Ana Florea , Frederick Fraunfelder , Tsaiyu Tseng , Y I Luo
{"title":"Corrigendum to Risk of Corneal Graft Rejection and Vaccination: A Matched Case-Control Study From a United States Integrated Health Care System Am J Ophthalmol 2024 Jul:263:133-140","authors":"Jennifer H Ku , Afshan A Nanji , Julia E Tubert , Cynthia Joe , Divya Srikumaran , Kevin L Winthrop , Amanda E Brunton , Ana Florea , Frederick Fraunfelder , Tsaiyu Tseng , Y I Luo","doi":"10.1016/j.ajo.2024.09.003","DOIUrl":"10.1016/j.ajo.2024.09.003","url":null,"abstract":"","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"268 ","pages":"Page 420"},"PeriodicalIF":4.1,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Assessment of PC–IOL Optic Apposition in Surface-Modified IOL and Its Impact on Nd:YAG Capsulotomy Rate and Visual Quality 表面改良型人工晶体中 PC-IOL 光学定位的长期评估及其对 Nd:YAG 包囊切除率和视觉质量的影响。
IF 4.1 1区 医学
American Journal of Ophthalmology Pub Date : 2024-09-28 DOI: 10.1016/j.ajo.2024.09.029
Manpreet Kaur, Jeewan S. Titiyal, Jyoti Rawat
{"title":"Long-Term Assessment of PC–IOL Optic Apposition in Surface-Modified IOL and Its Impact on Nd:YAG Capsulotomy Rate and Visual Quality","authors":"Manpreet Kaur,&nbsp;Jeewan S. Titiyal,&nbsp;Jyoti Rawat","doi":"10.1016/j.ajo.2024.09.029","DOIUrl":"10.1016/j.ajo.2024.09.029","url":null,"abstract":"<div><h3>Purpose</h3><div>To assess apposition of posterior capsule (PC) to intraocular lens (IOL) optic in ultraviolet (UV)/ozone surface modified IOL and its impact on neodymium-doped yttrium aluminum garnet (Nd:YAG) laser capsulotomy rate and visual quality.</div></div><div><h3>Design</h3><div>Prospective interventional case series.</div></div><div><h3>Methods</h3><div>The study enrolled 100 eyes implanted with UV/ozone surface modified hydrophobic acrylic IOL during phacoemulsification. The primary outcome measure was PC–optic apposition on anterior segment optical coherence tomography (ASOCT). Secondary outcomes were Nd:YAG capsulotomy and visual quality (ray-tracing aberrometry). Follow-up was performed on postoperative day (POD) 1, at 1, 3, and 6 months, and 1 and 2 years.</div></div><div><h3>Results</h3><div>Complete PC–optic apposition was observed in 4% of cases on POD1, which increased to 75% at 2 years. PC configuration in cases with PC–optic non-apposition was smooth (34.4%) or wavy (65.6%) on ASOCT; initial smooth PC was associated with significantly higher incidence of PC–optic apposition at 2 years (p=0.028). At 2 years, visual quality was significantly better in cases with complete PC–optic apposition in terms of Strehl ratio (<em>P</em> = .029), modulation transfer function (MTF) (<em>P</em> = 0.016), root mean square (RMS) aberrations (<em>P</em> = .024) and higher order aberrations (HOAs) (<em>P</em> = 0.043). A significant positive correlation was observed between height of interface fluid and total RMS (Pearson correlation coefficient 0.221; <em>P</em> = .027) and HOAs (Pearson correlation coefficient 0.198; <em>P</em> = .048). PCO developed in 7% of cases (7/100); of these, 6 cases had persistent PC–optic non-apposition. Nd:YAG laser capsulotomy was required in 3% (3/100) cases; all of these cases had persistent PC–optic non-apposition.</div></div><div><h3>Conclusions</h3><div>Long-term complete PC–optic apposition was observed in 75% of patients implanted with UV/ozone surface-modified IOLs. Complete PC–optic apposition is associated with lower Nd:YAG capsulotomy rate and superior visual quality.</div></div>","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"270 ","pages":"Pages 113-119"},"PeriodicalIF":4.1,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laser for congenital persistent pupillary membrane 激光治疗先天性瞳孔持续膜。
IF 4.1 1区 医学
American Journal of Ophthalmology Pub Date : 2024-09-28 DOI: 10.1016/j.ajo.2024.09.021
Baoyi Liu, Xiaojing Zhong, Tao Li
{"title":"Laser for congenital persistent pupillary membrane","authors":"Baoyi Liu,&nbsp;Xiaojing Zhong,&nbsp;Tao Li","doi":"10.1016/j.ajo.2024.09.021","DOIUrl":"10.1016/j.ajo.2024.09.021","url":null,"abstract":"","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"268 ","pages":"Pages e1-e2"},"PeriodicalIF":4.1,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Outcomes of Endothelial Keratoplasty With a Recipient's Entire Descemet Stripping for Iridocorneal Endothelial Syndrome 内皮角膜移植术配合整个受术者的 Descemet 剥脱术治疗虹膜角膜内皮综合征的临床效果。
IF 4.1 1区 医学
American Journal of Ophthalmology Pub Date : 2024-09-27 DOI: 10.1016/j.ajo.2024.09.024
Xiaojuan Dong , Chen Ouyang , Qinying Ye , Jing Wu , Chenjia Xu , Lingling Fu , Minglu Ma , Jiayin Peng , Ting Huang
{"title":"Clinical Outcomes of Endothelial Keratoplasty With a Recipient's Entire Descemet Stripping for Iridocorneal Endothelial Syndrome","authors":"Xiaojuan Dong ,&nbsp;Chen Ouyang ,&nbsp;Qinying Ye ,&nbsp;Jing Wu ,&nbsp;Chenjia Xu ,&nbsp;Lingling Fu ,&nbsp;Minglu Ma ,&nbsp;Jiayin Peng ,&nbsp;Ting Huang","doi":"10.1016/j.ajo.2024.09.024","DOIUrl":"10.1016/j.ajo.2024.09.024","url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate whether a recipient's entire Descemet stripping reduced endothelial cell loss (ECL) after Descemet membrane endothelial keratoplasty (DMEK) for iridocorneal endothelial (ICE) syndrome.</div></div><div><h3>Design</h3><div>Randomized controlled clinical trial.</div></div><div><h3>Methods</h3><div>A total of 48 patients (48 eyes) with ICE syndrome were enrolled between 10 March 2014 and 11 May 11 2022. The eligible patients were divided into the entire recipient's Descemet stripping group (entire stripping group, 24 eyes) or the standard technique group (standard group, 24 eyes). DMEK was performed in all cases with concomitant procedures. The recipient's entire Descemet membrane or the central 8.0- or 8.25-mm diameter of the Descemet membrane was removed intraoperatively. Main outcome measures were ECL, corrected distance visual acuity (CDVA), intraocular pressure (IOP), graft survival, and surgical complications, which were compared 9, 12, and 24 months after surgery.</div></div><div><h3>Results</h3><div>After a 9-month follow-up, ECL was significantly lower in the entire stripping group than in the standard group. At 2 years postoperatively, the ECL rate was 66% ± 5% and 74% ± 4% (95% CI: −0.04 to 0.01; <em>P</em> = .040), with a cumulative graft success rate of 83% and 67% (95% CI: −0.07 to 0.39; <em>P</em> = .318) in the entire stripping group and the standard group, respectively. The postoperative CDVA level was comparable between the 2 groups throughout the follow-up period. No significant differences between the 2 groups were observed in regard to the incidence of main complications.</div></div><div><h3>Conclusions</h3><div>Entire recipient's Descemet stripping may delay the pathological progression of ICE syndrome, thereby reducing ECL after DMEK.</div></div>","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"270 ","pages":"Pages 103-112"},"PeriodicalIF":4.1,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Choroid Involvement Secondary to Optic Disc Pit Maculopathy: OCT Analysis and Evolution After Surgical Treatment 继发于视盘凹陷性黄斑病变的脉络膜受累:OCT分析和手术治疗后的演变:视盘凹陷黄斑病变中的脉络膜受累。
IF 4.1 1区 医学
American Journal of Ophthalmology Pub Date : 2024-09-27 DOI: 10.1016/j.ajo.2024.09.022
Matteo Mario Carlà , Francesco Boselli , Federico Giannuzzi , Emanuele Crincoli , Tomaso Caporossi , Carlos Mateo , Stanislao Rizzo
{"title":"Choroid Involvement Secondary to Optic Disc Pit Maculopathy: OCT Analysis and Evolution After Surgical Treatment","authors":"Matteo Mario Carlà ,&nbsp;Francesco Boselli ,&nbsp;Federico Giannuzzi ,&nbsp;Emanuele Crincoli ,&nbsp;Tomaso Caporossi ,&nbsp;Carlos Mateo ,&nbsp;Stanislao Rizzo","doi":"10.1016/j.ajo.2024.09.022","DOIUrl":"10.1016/j.ajo.2024.09.022","url":null,"abstract":"<div><h3>Purpose</h3><div>To assess choroidal changes associated to optic disc pit maculopathy (ODP-M) and their evolution after surgical treatment.</div></div><div><h3>Design</h3><div>Multicentric retrospective case series.</div></div><div><h3>Methods</h3><div>An analysis of 42 patients affected by unilateral ODP-M undergoing surgical treatment between 2013 and 2023 was conducted. Optical coherence tomography (OCT) was performed at baseline and postoperative months 1, 6, 12, and 24 and most recent follow-up. Subfoveal choroidal thickness (SFCT) and peripapillary choroidal thickness (PPCT) were measured in ODP-M and fellow eyes. The presence of retinal pigmented epithelium (RPE) atrophy was used to distinguish between “early” and “advanced” disease, and data regarding fluid localization were collected.</div></div><div><h3>Results</h3><div>Baseline SFCT in ODP-M eyes was significantly higher than fellow eyes (386.8 ± 88.9 vs 334.4 ± 72.2 µm, <em>P</em> = 0.002), in contrast to PPCT (192.6 ± 47.8 vs 181.2 ± 45.7 µm, <em>P</em> = .46). SFCT significantly decreased 1 month postoperatively (mean reduction 36.5 µm, <em>P</em> = .009) and remained below preoperative values throughout the follow-up, showed a mean reduction of 79.4 µm at final follow-up (<em>P</em> &lt; .001). Conversely, PPCT showed no changes between preoperative and postoperative values (all <em>P</em> &gt; .05). Nine eyes (21.4%) showed submacular dilated choroidal vessels, correlated with the presence of subretinal fluid (<em>P</em> = .008) and reducing in caliber after surgical treatment. The 10 eyes (23.8%) with advanced disease had lower baseline SFCT and worse best-corrected visual acuity compared to the early disease subgroup, and showed a delayed reduction of choroidal swelling postoperatively.</div></div><div><h3>Conclusions</h3><div>Subfoveal choroid may thicken and remodel in response to ODP-M, eventually returning to physiological values after surgical treatment. Moreover, the presence of RPE atrophy may influence retino-choroidal balance. Conversely, PPCT did not show comparable modifications.</div></div>","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"270 ","pages":"Pages 120-130"},"PeriodicalIF":4.1,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Monofocal, Wavefront-Shaped, and Diffractive Trifocal Intraocular Lenses on Scanning-Slit Automated Refraction 单焦点、波前形和衍射三焦点眼内透镜对扫描缝隙自动屈光度的影响。
IF 4.1 1区 医学
American Journal of Ophthalmology Pub Date : 2024-09-26 DOI: 10.1016/j.ajo.2024.09.019
LARISSA GOUVEA , SARA ALSHAKER , KAROLINNE MAIA ROCHA , WALLACE CHAMON , CLARA C. CHAN , DAVID S. ROOTMAN
{"title":"Effect of Monofocal, Wavefront-Shaped, and Diffractive Trifocal Intraocular Lenses on Scanning-Slit Automated Refraction","authors":"LARISSA GOUVEA ,&nbsp;SARA ALSHAKER ,&nbsp;KAROLINNE MAIA ROCHA ,&nbsp;WALLACE CHAMON ,&nbsp;CLARA C. CHAN ,&nbsp;DAVID S. ROOTMAN","doi":"10.1016/j.ajo.2024.09.019","DOIUrl":"10.1016/j.ajo.2024.09.019","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare scanning-slit retinoscopy automated refraction spherical equivalent (ARSE) to subjective manifest refraction spherical equivalent (MRSE) in normal eyes with four different types of intraocular lenses (IOLs).</div></div><div><h3>Design</h3><div>Retrospective cross-sectional study.</div></div><div><h3>Methods</h3><div>A total of 279 pseudophakic eyes that underwent lens extraction at a private center with implantation of either a wavefront shaped IOL (Acrysof® Vivity, DFT015), a nonapodized diffractive trifocal IOL (Acrysof® Panoptix), or a monofocal IOL with negative spherical aberration (Tecnis ZCBOO) or aberration-free (Envista Mx60E). Patients who had an automated refraction measurement with retinoscopy refractometer and aberrometer (NIDEK OPD Scan III, Nidek Technologies) and subjective refraction data 1-2 months postoperatively were included in the study. Main outcome measured was the difference between automated refraction and subjective refraction.</div></div><div><h3>Results</h3><div>Sixty-one eyes implanted with a DFT015 IOL, 78 eyes with a TFNT00 IOL, 40 with a ZCBOO IOL and 100 with a Mx60E IOL were enrolled in this study. Statistically significant myopic results were observed when using ARSE compared to MRSE in the DFT015 (-0.95 ± 0.64, -0.33 ± 0.65, <em>P</em> &lt; .001), TFNT00 (-0.43 ± 0.36, -0.2 ± 0.35, <em>P</em> &lt; .001), ZCBOO (-0.81 ± 0.63, -0.4 ± 0.69, <em>P</em> = .008) and Mx60E (-0.75 ± 0.65, -0.45 ± 0.52; <em>P</em> &lt; .05) IOL groups. The absolute difference between the 2 methods was statistically significant in the DFT015 IOL group (0.65 ± 0.49; <em>P</em> &lt; .05).</div></div><div><h3>Conclusion</h3><div>Automated refraction yields myopic results in pseudophakic eyes with monofocal and presbyopia correcting IOLs and may be used with caution. Manifest refraction “push-plus” technique should be used in all pseudophakic eyes to avoid over-minus prescriptions, especially in patient with residual refractive error following cataract surgery.</div></div>","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"269 ","pages":"Pages 450-456"},"PeriodicalIF":4.1,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment Outcomes and Definition Inconsistencies in High-Risk Unilateral Retinoblastoma 高风险单侧视网膜母细胞瘤的治疗结果和定义不一致:高风险Rb.
IF 4.1 1区 医学
American Journal of Ophthalmology Pub Date : 2024-09-25 DOI: 10.1016/j.ajo.2024.09.023
MATTAN ARAZI , ALONA BAUM , SANDRO CASAVILCA-ZAMBRANO , Sandra Alarcon-Leon , ROSDALI DIAZ-CORONADO , ALIA AHMAD , ASMA MUSHTAQ , MAHVISH HUSSAIN , TATIANA USHAKOVA , SEROV YURI , POLYAKOV VLADIMIR , CAROL L. SHIELDS , RALPH C. EAGLE Jr , JESSE L. BERRY , SARAH PIKE , BRIANNE BROWN , SOMA RANI ROY , FAHMIDA HUQUE , INA FABIAN , SHAHAR FRENKEL , IDO DIDI FABIAN
{"title":"Treatment Outcomes and Definition Inconsistencies in High-Risk Unilateral Retinoblastoma","authors":"MATTAN ARAZI ,&nbsp;ALONA BAUM ,&nbsp;SANDRO CASAVILCA-ZAMBRANO ,&nbsp;Sandra Alarcon-Leon ,&nbsp;ROSDALI DIAZ-CORONADO ,&nbsp;ALIA AHMAD ,&nbsp;ASMA MUSHTAQ ,&nbsp;MAHVISH HUSSAIN ,&nbsp;TATIANA USHAKOVA ,&nbsp;SEROV YURI ,&nbsp;POLYAKOV VLADIMIR ,&nbsp;CAROL L. SHIELDS ,&nbsp;RALPH C. EAGLE Jr ,&nbsp;JESSE L. BERRY ,&nbsp;SARAH PIKE ,&nbsp;BRIANNE BROWN ,&nbsp;SOMA RANI ROY ,&nbsp;FAHMIDA HUQUE ,&nbsp;INA FABIAN ,&nbsp;SHAHAR FRENKEL ,&nbsp;IDO DIDI FABIAN","doi":"10.1016/j.ajo.2024.09.023","DOIUrl":"10.1016/j.ajo.2024.09.023","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare the clinical outcomes of children with unilateral retinoblastoma (Rb) and high-risk histopathology features (HRHF) following upfront enucleation with/without adjuvant chemotherapy, and investigate cases locally considered non-HRHF but converted to a standardized HRHF definition.</div></div><div><h3>Design</h3><div>Retrospective multinational clinical cohort study.</div></div><div><h3>Methods</h3><div>Children with Rb who presented to 21 centers from 12 countries between 2011-2020, and underwent primary enucleation were recruited. Centers retrieved clinical data and were asked to report detailed histopathology findings, as well as indicate cases defined locally as high-risk. For analysis, only unilateral cases with standardized HRHF, defined as retrolaminar optic nerve invasion, massive choroidal invasion, scleral invasion, anterior-segment involvement, and/or combined nonmassive choroidal and prelaminar/laminar optic nerve invasion, were included. Main outcome measures included orbital tumor recurrence, systemic metastasis, survival and number, and outcome of cases converted to standardized HRHF.</div></div><div><h3>Results</h3><div>A total of 600 children presenting to 14 centers in 9 countries were included. Of these, 505 (84.2%) were considered locally as HRHF and received adjuvant chemotherapy. After a median follow-up period of 39.2 ± 1.6 months (range: 0.8-60.0 months), 36 (6.0%) had orbital tumor recurrence, 49 (8.2%) metastasis, and 72 (12.0%) children died. Children not receiving adjuvant chemotherapy were at significantly increased risk of orbital tumor recurrence, metastasis, and death (<em>P</em> ≤ .002). Of the study children, 63/600 (10.5%) were considered locally non-HRHF, but converted to standardized HRHF and included in the analysis. Of these, 6/63 (9.5%) had orbital tumor recurrence, 5/63 (7.9%) metastasis, and 6/63 (9.5%) children died. Isolated minor choroidal invasion with prelaminar/laminar optic nerve invasion was reported in 114 (19.0%) children, but considered locally as HRHF only in 68/114 (59.6%). Of these, 6/114 (5.3%) children developed metastasis and subsequently died, yielding a number needed to treat of 15.</div></div><div><h3>Conclusion</h3><div>Based on this multinational cohort of children with Rb, we recommend the use of adjuvant chemotherapy following upfront enucleation and diagnosis of HRHF. Variation exists worldwide among centers when defining HRHF, resulting in adverse patient outcomes, warranting standardization.</div></div>","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"268 ","pages":"Pages 399-408"},"PeriodicalIF":4.1,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142329255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Era of Ophthalmology Leadership? A Descriptive and Comparative Analysis of Ophthalmology Department Chairs in 2024 眼科领导力的新时代?对 2024 年眼科系主任的描述性和比较性分析。
IF 4.1 1区 医学
American Journal of Ophthalmology Pub Date : 2024-09-21 DOI: 10.1016/j.ajo.2024.09.020
Samuel A. Cohen , Victoria L. Tseng , Jayanth Sridhar , Anne L. Coleman
{"title":"A New Era of Ophthalmology Leadership? A Descriptive and Comparative Analysis of Ophthalmology Department Chairs in 2024","authors":"Samuel A. Cohen ,&nbsp;Victoria L. Tseng ,&nbsp;Jayanth Sridhar ,&nbsp;Anne L. Coleman","doi":"10.1016/j.ajo.2024.09.020","DOIUrl":"10.1016/j.ajo.2024.09.020","url":null,"abstract":"<div><h3>Purpose</h3><div>To (1) characterize and analyze the demographics and scholarly achievements of United States (US) academic ophthalmology department chairs, and (2) to elucidate trends in the academic and demographic profiles of newly hired department chairs.</div></div><div><h3>Design</h3><div>Cross-sectional study.</div></div><div><h3>Methods</h3><div>Online search of publicly available resources conducted January 1, 2024.</div></div><div><h3>Patient or Study Population</h3><div>One hundred seven ophthalmology chairs of accredited US departments.</div></div><div><h3>Main Outcome Measures</h3><div>Department chair demographic and academic data.</div></div><div><h3>Results</h3><div>Of 107 chairs analyzed, 83% (89/107) are male. The mean age of chairs is 60.9 ± 7.9 years and the mean age at appointment is 51.9 ± 7.6 years. There has been significant turnover in department chairs recently, with 47 (44%) chairs having been newly appointed in the past 7 years. Approximately 40% (n = 41) of current chairs completed ≥1 component of their medical training at the program where they are currently chair. Approximately one-third (33/107 [31%]) of current chairs earned an additional graduate degree, most frequently a PhD (17/107 [16%]), MBA (10/107 [8%]), and MS (8/107 [4%]). More than 96% (n = 103) of chairs completed a clinical fellowship, often in vitreoretinal surgery (30/107 [28%]), cornea (27/107 [25%]), or glaucoma (24/107 [22%]). The average number of peer-reviewed publications among chairs is 214.9 ± 294.7 (range 0-1901), and the mean h-index is 35.0 ± 25.4 (range 0-147). When comparing profiles of newly appointed chairs in the past 7 years to chairs appointed before 2017, there was not a statistically significant difference in gender distribution (21% female vs 13% female, respectively, <em>P</em> = .276). Newly hired chairs were significantly older at the time of their appointment to chair (54 years vs 50 years, respectively, <em>P</em> = .008) and averaged significantly more years from residency completion to appointment as chair (23 years vs 19 years, respectively, <em>P</em> = .005).</div></div><div><h3>Conclusions</h3><div>Ophthalmology department chairs remain predominantly fellowship-trained males who have frequently trained at the institution they currently chair. Newly hired chairs have accumulated more experience before their appointment, starting the role later in their careers, with implications for the frequency of future chair turnover. While females compose a higher proportion of newly hired chairs in the past 7 years compared with previous periods of time, females remain underrepresented in ophthalmology chair positions.</div></div>","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"269 ","pages":"Pages 373-380"},"PeriodicalIF":4.1,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142306851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Herpes Zoster Ophthalmicus Uveitis: Onset and Complications 带状疱疹眼葡萄膜炎:发病和并发症:带状疱疹葡萄膜炎。
IF 4.1 1区 医学
American Journal of Ophthalmology Pub Date : 2024-09-20 DOI: 10.1016/j.ajo.2024.09.017
JAY J. MEYER, KEVIN LIU, HELEN V. DANESH-MEYER, RACHAEL L. NIEDERER
{"title":"Herpes Zoster Ophthalmicus Uveitis: Onset and Complications","authors":"JAY J. MEYER,&nbsp;KEVIN LIU,&nbsp;HELEN V. DANESH-MEYER,&nbsp;RACHAEL L. NIEDERER","doi":"10.1016/j.ajo.2024.09.017","DOIUrl":"10.1016/j.ajo.2024.09.017","url":null,"abstract":"<div><h3>Purpose</h3><div>To describe the timing of uveitis onset and frequency of associated complications in individuals with herpes zoster ophthalmicus (HZO).</div></div><div><h3>Design</h3><div>Retrospective, cohort study.</div></div><div><h3>Methods</h3><div>Individuals with acute HZO seen at the Auckland District Health Board from 2006 to 2016 were studied. The primary outcome measures were the proportion who developed uveitis and time to diagnosis of uveitis following the onset of HZO. Secondary outcome measures included complications of HZO uveitis and effects of prompt antiviral (within 72 hours) on outcomes.</div></div><div><h3>Results</h3><div>A total of 869 patients with HZO were included for analysis, of whom 413 (47.6%) developed uveitis. Median time from onset of rash to diagnosis of uveitis was 10 days (IQR 6-14). Of the 658 individuals examined within the first week following rash onset (days 0 through 7), 17.6% (116/658) were diagnosed with uveitis at that initial presenting examination, with an additional 24.9% (164/658) diagnosed with uveitis at a subsequent visit. Complications were higher in eyes with uveitis, including moderate or severe vision loss, corneal scarring, neurotrophic keratitis, band keratopathy, corneal melt, elevated intraocular pressure, glaucoma, and cataract (all <em>P</em> &lt; .01). Prompt antiviral was associated with a lower rate of moderate vision loss among eyes with uveitis (<em>P</em> = .02).</div></div><div><h3>Conclusions</h3><div>Uveitis occurred in approximately half of individuals with HZO and was most frequently diagnosed during the second week following rash onset. Eyes with uveitis were more likely to have other ocular complications and loss of vision.</div></div>","PeriodicalId":7568,"journal":{"name":"American Journal of Ophthalmology","volume":"268 ","pages":"Pages 409-415"},"PeriodicalIF":4.1,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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