Skin health and disease最新文献

{"title":"Evaluating mental health support by healthcare providers for patients with atopic dermatitis: A cross‐sectional survey","authors":"Sheena Chatrath, A. Loiselle, J. Johnson, W. Begolka","doi":"10.1002/ski2.408","DOIUrl":"https://doi.org/10.1002/ski2.408","url":null,"abstract":"Atopic dermatitis (AD) is associated with psychosocial symptoms, resulting in significant mental health burden and reduced quality of life.To understand mental health support received by patients from their primary eczema provider.We administered a cross‐sectional survey (N = 954) to US caregivers and adult patients with AD.The National Eczema Association (United States) conducted an online survey in October 2022 among self‐selected patients and caregivers.Patients and caregivers of AD patients reported on mental health conversations and types of mental health support received by their/their child's provider.Many patients did not discuss (41.9%) or were not asked (50.5%) about their mental health by their eczema provider, and 64% reported not receiving a mental health referral. Patients were more likely to receive mental health support if they were male (2.00 [1.08–3.69]), low or middle education level (4.89 [2.10–11.36], 2.71 [1.36–5.40]), or had purchased insurance policies (4.43 [1.79–10.98]). Providers were most likely to refer patients to counseling services (22.5%), followed by alternative mental health therapy (14.9%), cognitive behavioural therapy (13.3%) and peer/social support groups (12.2%).Despite the strong association between AD and mental health conditions, there is a significant proportion of patients that report not receiving mental health support from their/their child's primary eczema provider. Screening with validated measures may improve the identification of patients requiring additional support. Future research should evaluate the efficacy of mental health resources and barriers to accessing and referring patients for mental health care.","PeriodicalId":74804,"journal":{"name":"Skin health and disease","volume":"7 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141337366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient experience: Feeling like the tin man from the Wizard of Oz","authors":"Caoimhe Dalton, L. Murphy, Carmel Ann Galligan, Susan O'Gorman, Larry Bacon, Claudine Howard‐James, Rachel Dillon, Holly Fitzgerald","doi":"10.1002/ski2.406","DOIUrl":"https://doi.org/10.1002/ski2.406","url":null,"abstract":"","PeriodicalId":74804,"journal":{"name":"Skin health and disease","volume":"42 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141340009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of a surgical logbook to improve training and patient safety: A retrospective analysis of 6 years' experience in Bristol, UK","authors":"E. Wasson, Charankumal Thandi, Adam Bray","doi":"10.1002/ski2.386","DOIUrl":"https://doi.org/10.1002/ski2.386","url":null,"abstract":"Logbooks can be a useful educational tool. Although their use in medical training has been greatly explored, there is limited research into their application throughout a clinician's career. We created a surgical logbook to allow clinicians to record their skin surgery procedures and reflect on the histological diagnosis and clearance margins achieved.We provide a retrospective analysis to evaluate the usefulness of the logbook as an analytical and educational tool in a dermatology department, particularly for maintaining exemplary complete excision rates.Data was collected from clinicians who conducted skin surgery in Bristol, UK. Cases were entered at the time of surgery, collecting data on body site, clinical margin, suspected diagnosis, type of procedure and closure. Following receipt of histological results, data on histological excision margins and tumour type was entered. Each clinician submitted data for a minimum of 3 months each year, and data collection ran from April 2012 until March 2018.Data from 5161 excision surgeries was collected over the 6‐year period. On histological diagnosis, excisions constituted 50% Basal Cell Carcinoma (BCC), 12% Squamous Cell Carcinoma (SCC), 9% Malignant Melanoma (MM) and 1% Lentigo Maligna (LM), and 28% ‘Other’ (rarer malignancies, melanoma wide local excision scars and pre‐cancerous/benign lesions). The department was found to have good diagnostic concordance: BCC 92%, SCC 87%, MM 80% and LM 53%. Overall complete excision rate was high at 97.07%. The most successfully excised cancer was BCC (97.50%), then SCC (97.14%) MM (96.48%) and LM (95.23%). The department provided many complex surgeries including 8.3% flaps and 8.5% grafts. Average lesion diameter was 11 mm (range 2–90 mm). There was a significant improvement in excision rates seen over the years for BCC, MM and LM. Although there was no significant difference found for SCC, this group began the study with already high clearance rates.This surgical logbook supports improved training and continues professional development. We encourage more departments to use this logbook and share the data that they produce. This could improve their excision rates, patient experience, and save them up to £28 000 per year.","PeriodicalId":74804,"journal":{"name":"Skin health and disease","volume":"2 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141378508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond caregiving: Navigating life with a developmentally disabled daughter with a severe case of Hidradenitis Suppurativa","authors":"Elisha M Myers, Janelle S. Nassim","doi":"10.1002/ski2.403","DOIUrl":"https://doi.org/10.1002/ski2.403","url":null,"abstract":"","PeriodicalId":74804,"journal":{"name":"Skin health and disease","volume":"8 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141266264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The acronymisation of lichen sclerosus","authors":"Georgios Kravvas, Christopher Bunker","doi":"10.1002/ski2.401","DOIUrl":"https://doi.org/10.1002/ski2.401","url":null,"abstract":"The short communication highlights a debate over the use of acronyms in medical literature, particularly focusing on “LSc” versus “LS” for lichen sclerosus. Despite the contested nature of the issue, we argue for the adoption of “LSc” due to its clarity and to avoid confusion with other medical terms. To best reflect the evolving nature of medical terminology and the authors' expertise, we also advocate for the authors' rights in choosing acronyms within their work.","PeriodicalId":74804,"journal":{"name":"Skin health and disease","volume":"10 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141266397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Annular elastolytic giant cell granuloma associated with autoimmune hepatitis: Response to ciclosporin","authors":"Zaina Sharif, Shagayegh Javadzadeh, Jeanne Boissiere, Daniel Creamer","doi":"10.1002/ski2.393","DOIUrl":"https://doi.org/10.1002/ski2.393","url":null,"abstract":"A 47 year old Caucasian female with a background of type 2 diabetes mellitus, hypothyroidism, and autoimmune hepatitis presented with a painful, pruritic, papular eruption in a photosensitive distribution across the upper chest, neck, face, dorsal hands and forearms. On examination, lesions coalesced into annular plaques each with an active, raised margin and an atrophic, yellow centre. Histopathology demonstrated an absence of mucin and elastophagocytosis with giant cells engulfing dermal elastin fibres. These histopathological features favoured a diagnosis of annular elastolytic giant cell granuloma (AEGCG). The patient was managed ciclosporin monotherapy 125 mg twice daily (3 mg/kg/day). At 8 week review, there was a marked improvement in the physical appearance of the dermatosis as well as diminishing of symptoms such as itch and cutaneous pain. AEGCG is a rare inflammatory dermatosis typically affecting sun‐exposed sites. It has been proposed that AEGCG is triggered by a solar induced elastolysis however other theories suggest it is a primary granulomatous disorder and not a photodermatosis. AEGCG appears to be aligned to an autoimmune diathesis, indicated by its frequent association with autoimmune conditions such as Hashimoto’s thyroiditis, vitiligo, giant cell arteritis and, as in our patient, auto‐immune hepatitis. Diabetes mellitus occurring concurrently with AEGCG has also been observed, again like our patient. Histopathological features which distinguish AEGCG from granuloma annulare include absent mucin, absent necrobiosis, giant cells with more nuclei, non‐palisading granulomata and marked loss of elastic tissue. AEGCG is often unresponsive to standard therapies. The literature indicates varying responses to photo‐protection, topical/systemic/intralesional corticosteroids, and oral medications such as methotrexate, hydroxychloroquine, and dapsone. Few case reports have also documented improvement with ciclosporin. In aggressive forms of AEGCG, as in our patient, treatment with ciclosporin may be an effective intervention and should be initiated early in the disease.","PeriodicalId":74804,"journal":{"name":"Skin health and disease","volume":"41 50","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141270031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding and treating diabetic foot ulcers: Insights into the role of cutaneous microbiota and innovative therapies.","authors":"Paul Norton, Pavlos Trus, Fengyi Wang, M Julie Thornton, Chien-Yi Chang","doi":"10.1002/ski2.399","DOIUrl":"10.1002/ski2.399","url":null,"abstract":"<p><strong>Background: </strong>Notoriously known as the silent pandemic, chronic, non-healing diabetic foot ulcers (DFUs), pose a significant rate of incidence for amputation and are a major cause of morbidity. Alarmingly, the treatment and management strategies of chronic wounds represent a significant economic and health burden as well as a momentous drain on resources with billions per annum being spent in the US and UK alone. Defective wound healing is a major pathophysiological condition which propagates an acute wound to a chronic wound, further propelled by underlying conditions such as diabetes and vascular complications which are more prevalent amongst the elderly. Chronic wounds are prone to infection, which can exacerbate the condition, occasionally resulting in amputation for the patient, despite the intervention of modern therapies. However, amputation can only yield a 5-year survival rate for 50% of patients, highlighting the need for new treatments for chronic wounds.</p><p><strong>Findings: </strong>The dynamic cutaneous microbiota is comprised of diverse microorganisms that often aid wound healing. Conversely, the chronic wound microbiome consists of a combination of common skin commensals such as <i>Staphylococcus aureus</i> and <i>Staphylococcus epidermidis</i>, as well as the opportunistic pathogen <i>Pseudomonas aeruginosa</i>. These bacteria have been identified as the most prevalent bacterial pathogens isolated from chronic wounds and contribute to prolific biofilm formation decreasing the efficiency of antimicrobials and further perpetuating a hyper-inflammatory state.</p><p><strong>Discussion and conclusion: </strong>Here, we review recent advances and provide a new perspective on alternative treatments including phage and microbiome transplant therapies and how the definitive role of the cutaneous microbiota impacts the aetiology of DFUs.</p>","PeriodicalId":74804,"journal":{"name":"Skin health and disease","volume":"4 4","pages":"e399"},"PeriodicalIF":0.0,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11297444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141895187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reducing injection discomfort in dermatology outpatient clinics.","authors":"Mohammad Alzaid, Faisal R Ali","doi":"10.1002/ski2.402","DOIUrl":"10.1002/ski2.402","url":null,"abstract":"","PeriodicalId":74804,"journal":{"name":"Skin health and disease","volume":"4 4","pages":"e402"},"PeriodicalIF":0.0,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11297450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141895051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beliefs, behaviours, and attitudes towards tanning and melanoma in the Irish population.","authors":"Catriona Gallagher, Cathal O'Connor, Eimear Gilhooley, John Bourke, Michelle Murphy","doi":"10.1002/ski2.398","DOIUrl":"10.1002/ski2.398","url":null,"abstract":"<p><strong>Background: </strong>The incidence of melanoma continues to rise in Ireland. Skin cancer prevention campaigns rely on promoting knowledge to improve sun-related behaviour.</p><p><strong>Objectives: </strong>To explore beliefs, behaviours, and attitudes towards tanning, and confidence in identifying signs of melanoma in the Irish population.</p><p><strong>Methods: </strong>A cross-sectional study was performed via an online questionnaire, with questions related to tanning, sun exposure, and skin cancer behaviours. Respondents were recruited according to gender, age and geographic region.</p><p><strong>Results: </strong>The questionnaire was completed by 1043 respondents (response rate 85%). Mean age was 41 years (range 20-72 years). Participants had mixed awareness of risk reduction strategies for melanoma but had high perceived concerns about developing melanoma. However, 48.9% regularly sunbathed when sunny in Ireland and 41.5% had used tanning beds. The most common reason for not photoprotecting while sunbathing was because it prevented tanning. Nearly half (45.9%) of those who sunbathed agreed that it was worth getting sunburned to get a tan, and 69.4% reported feeling and looking better with a tan. Less than half (42.4%) felt confident about what to look for when checking their skin for melanoma.</p><p><strong>Conclusions: </strong>This study underscores the importance of addressing the cultural and aesthetic aspects of sun-tanning behaviour in skin cancer prevention efforts, as well as increasing awareness of skin cancer signs and self-examination. Further research into the potential addictive nature of UV-seeking behaviour may offer new avenues for intervention and support for individuals who are addicted to tanning.</p>","PeriodicalId":74804,"journal":{"name":"Skin health and disease","volume":"4 5","pages":"e398"},"PeriodicalIF":0.0,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11442063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudoprogression of cutaneous squamous cell carcinoma invading the super vermillion border following programmed death-1 inhibitor monotherapy.","authors":"Sach Thakker, Naghmeh Yousefzadeh, Jafar Al-Mondhiry","doi":"10.1002/ski2.400","DOIUrl":"10.1002/ski2.400","url":null,"abstract":"<p><p>A 55-year-old woman with a moderately differentiated cutaneous squamous cell carcinoma (cSCC) of the upper lip experienced initial tumour growth and new lymphadenopathy after starting immunotherapy with Cemiplimab, but achieved complete remission with no adverse events after five infusions. This case underscores the potential of immunotherapy for cSCC in sensitive head and neck areas and illustrates the phenomenon of pseudoprogression, where apparent tumour growth can occur before clinical improvement.</p>","PeriodicalId":74804,"journal":{"name":"Skin health and disease","volume":"4 4","pages":"e400"},"PeriodicalIF":0.0,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11297434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141895050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}