Linear atrophoderma of Moulin: A rare case report and review of the literature

Q3 Medicine
Moatasem Hussein Al‐janabi, Sdrah Diab, Ghina Aljammal, Lina Kassab, Z. Al-shehabi, Lina Al‐Soiufi
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引用次数: 0

Abstract

Linear atrophoderma of Moulin (LAM) is an uncommon dermatological disease characterised by linear, depressed plaques typically following Blaschko's lines. LAM generally occurs in adolescence or early adulthood and is more commonly observed in females. The aetiology of LAM is still unclear. We report a rare case of LAM in an 18‐year‐old female presenting with an atypical Blaschkoid distribution (multiple band‐like pattern) on her right trunk. A clinical examination and histopathological analysis were performed to make the diagnosis. Partial improvement was obtained with calcipotriol and colchicine. LAM is a rare condition; we were only able to identify 23 case reports in the published literature. The findings of this report contribute to the limited literature on LAM, highlighting the clinical variability of LAM and suggesting potential novel variants beyond the classic presentation, emphasising the importance of recognising diverse manifestations for accurate diagnosis and management. Early recognition of LAM is crucial for appropriate treatment and improved patient outcomes. Further research is needed to elucidate LAM's aetiology and underlying mechanisms to facilitate the development of more targeted therapeutic strategies.
穆兰线性萎缩性皮肤病:罕见病例报告和文献综述
莫兰线性萎缩性苔藓(LAM)是一种不常见的皮肤病,其特征是典型的布拉斯克纹线状凹陷斑块。LAM 通常发生在青春期或成年早期,多见于女性。LAM的病因尚不清楚。我们报告了一例罕见的 LAM 病例,患者为一名 18 岁女性,右侧躯干出现不典型的布拉斯克氏线分布(多条带状)。经临床检查和组织病理学分析后确诊。使用钙泊三醇和秋水仙碱后,病情得到部分改善。LAM 是一种罕见病,我们只能在已发表的文献中找到 23 个病例报告。本报告的研究结果为有限的 LAM 文献做出了贡献,突出了 LAM 的临床变异性,并提出了经典表现之外的潜在新型变异,强调了识别不同表现对准确诊断和治疗的重要性。早期识别 LAM 对适当治疗和改善患者预后至关重要。我们需要进一步开展研究,以阐明 LAM 的病因和内在机制,从而促进更具针对性的治疗策略的开发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.70
自引率
0.00%
发文量
0
审稿时长
10 weeks
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