Revue francophone des laboratoires : RFL最新文献

{"title":"Le cadmium sous double surveillance","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(26)76699-5","DOIUrl":"10.1016/S1773-035X(26)76699-5","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2026 584","pages":"Page 5"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148661365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maladie de Lyme : ce que l’on sait du futur vaccin","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(26)76704-6","DOIUrl":"10.1016/S1773-035X(26)76704-6","url":null,"abstract":"<div><h3>Résumé</h3><div><strong>Un vaccin adapté à l’infection humaine dite maladie de Lyme, développé par le laboratoire américain Pfizer et le laboratoire Valneva – société franco-autrichienne spécialisée dans le développement, la production et la commercialisation de vaccins contre des maladies infectieuses – a présenté une efficacité de 73,2 % lors des essais de phase 3, ce qui pourrait en faire le premier vaccin approuvé pour l’usage chez les humains</strong>.</div></div>","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2026 584","pages":"Page 8"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148656458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"L’EMA approuve une molécule pour maladie rare : l’hypertriglycéridémie","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(26)76705-8","DOIUrl":"10.1016/S1773-035X(26)76705-8","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2026 584","pages":"Page 9"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148656459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Un numéro vert pour aider les aidants","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(26)76706-X","DOIUrl":"10.1016/S1773-035X(26)76706-X","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2026 584","pages":"Page 9"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148657156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caractérisation génomique d’une souche de Mycobacterium tuberculosis multirésistante isolée chez un bovin à Djibouti","authors":"Samia Kahsay Hagos,&nbsp;Chloé Dupont,&nbsp;Hasna Said Mohamed,&nbsp;Christian Carrière,&nbsp;Guilhem Conquet,&nbsp;Bastien Baud,&nbsp;Hamadoun Garba,&nbsp;Mohamed Osman Hassan,&nbsp;Mohamed H. Aboubaker,&nbsp;Sylvain Godreuil","doi":"10.1016/S1773-035X(26)76724-1","DOIUrl":"10.1016/S1773-035X(26)76724-1","url":null,"abstract":"<div><h3>Résumé</h3><div>Nous présentons ici la première étude utilisant des méthodes microbiologiques et génétiques pour analyser la tuberculose bovine (bTB) dans des carcasses d’abattoir, ainsi que la première description d’une infection à <em>Mycobacterium tuberculosis</em> (MTB) multirésistant (MTB-MDR) (MDR pour <em>Multi-Drug Resistant</em>) chez des bovins à Djibouti. La mise en évidence de MTB-MDR chez les bovins soulève d’importantes préoccupations quant à une possible transmission bidirectionnelle entre l’humain et l’animal. Cette situation pourrait compliquer les efforts de lutte contre la tuberculose en favorisant l’introduction de souches résistantes dans la population humaine, par contact direct ou par la consommation de produits d’origine animale contaminés. En outre, les bovins pourraient devenir des réservoirs de souches MTB-MDR, contribuant ainsi à l’amplification et à la propagation de ces isolats en l’absence de mesures adéquates de détection et de contrôle.</div></div><div><h3>Abstract</h3><div>Here, we present the first study to apply microbiological and genetic approaches to investigate bovine tuberculosis (bTB) in slaughterhouse carcasses, as well as the first report of Mycobacterium tuberculosis infection in cattle in Djibouti. The identification of multidrug-resistant (MDR) M. tuberculosis in cattle raises serious concerns regarding potential bidirectional transmission between humans and animals. Such transmission could complicate tuberculosis control efforts by facilitating the introduction of drug-resistant strains into the human population through direct contact or the consumption of contaminated animal products. Moreover, cattle may act as reservoirs for drug-resistant TB strains, thereby contributing to the amplification and dissemination of resistance genes in the absence of adequate detection and control measures.</div></div>","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2026 584","pages":"Pages 43-45"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148660965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"QCM Évaluez-vous !","authors":"","doi":"10.1016/S1773-035X(26)76731-9","DOIUrl":"10.1016/S1773-035X(26)76731-9","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2026 584","pages":"Pages 75-77"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148661222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"QCM Évaluez-vous !","authors":"","doi":"10.1016/S1773-035X(26)76731-9","DOIUrl":"10.1016/S1773-035X(26)76731-9","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2026 584","pages":"Pages 75-77"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148661315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Médecine esthétique: quand de faux praticiens manipulent des produits professionnels","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(26)76714-9","DOIUrl":"10.1016/S1773-035X(26)76714-9","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2026 584","pages":"Page 15"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148657078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ce que l’on sait du hantavirus…: et ce qu’il faut en faire","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(26)76702-2","DOIUrl":"10.1016/S1773-035X(26)76702-2","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2026 584","pages":"Pages 6-7"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148657152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phaeohyphomycose sous-cutanée à Alternaria chez le patient transplanté rénal : une entité à savoir reconnaître en 2026","authors":"Guillaume Desoubeaux","doi":"10.1016/S1773-035X(26)76723-X","DOIUrl":"10.1016/S1773-035X(26)76723-X","url":null,"abstract":"<div><h3>Résumé</h3><div>L’alternariose constitue une infection opportuniste due à des moisissures pigmentées du genre <em>Alternaria</em>, ubiquitaire dans l’environnement. Elle survient surtout chez les patients immunodéprimés, en premier lieu les transplantés rénaux, mais aussi beaucoup plus rarement chez des sujets immunocompétents après inoculation cutanée traumatique. La présentation est dominée par des atteintes cutanées et sous-cutanées (nodules, plaques infiltrées, ulcérations des zones exposées), plus rarement respiratoires. Le diagnostic repose sur la réalisation de prélèvements superficiels ou profonds, l’examen direct montrant des filaments septés et pigmentés, et la culture des colonies brun-noir ; une confirmation moléculaire peut être utile. L’interprétation doit rester prudente car <em>Alternaria</em> demeure un contaminant fréquent. La prise en charge associe le plus souvent un azolé (itraconazole ou voriconazole), une exérèse chirurgicale des lésions localisées si possible, et une réduction de l’immunosuppression ; l’évolution est généralement favorable mais des rechutes sont possibles.</div></div><div><h3>Abstract</h3><div>Alternariosis refers to opportunistic infection caused by ubiquitous environmental molds of the genus <em>Alternaria</em>. It mainly affects immunocompromised patients but can also occur in immunocompetent hosts following traumatic cutaneous inoculation. Clinical presentation is predominantly cutaneous or subcutaneous (nodules, infiltrated plaques, ulcerations on exposed areas), with rarer respiratory or disseminated forms. Diagnosis relies on superficial or deep samples (especially biopsy), direct microscopy showing pigmented septate hyphae, culture yielding brown to black colonies; molecular tools may assist identification. Interpretation requires caution as <em>Alternaria</em> is a frequent contaminant. Management typically includes an azole (itraconazole or voriconazole), surgical excision of localized lesions when feasible, and reduction of immunosuppression; outcomes are generally favorable, although relapses can occur.</div></div>","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2026 584","pages":"Pages 38-42"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148660964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}