Revue francophone des laboratoires : RFL最新文献

{"title":"Un premier glucomètre en continu en pharmacie ou sur abonnement","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76354-6","DOIUrl":"10.1016/S1773-035X(25)76354-6","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 572","pages":"Page 5"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Le Youth Hub : un carrefour des jeunes VIH+","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76356-X","DOIUrl":"10.1016/S1773-035X(25)76356-X","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 572","pages":"Page 6"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Les associations de patients soutiennent le rapport de la Cour des comptes","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76357-1","DOIUrl":"10.1016/S1773-035X(25)76357-1","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 572","pages":"Page 7"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Textes juridiques","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76367-4","DOIUrl":"10.1016/S1773-035X(25)76367-4","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 572","pages":"Page 13"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leucémies aiguës lymphoblastiques T : apport du phénotypage","authors":"Ludovic Lhermitte ,&nbsp;Lucien Courtois","doi":"10.1016/S1773-035X(25)76374-1","DOIUrl":"10.1016/S1773-035X(25)76374-1","url":null,"abstract":"<div><h3>Résumé</h3><div>Les leucémies aiguës lymphoblastiques T (LAL-T) constituent un groupe hétérogène d’hémopathies lymphoïdes immatures caractérisées par l’expansion clonale de précurseurs T bloqués dans la progression de leur différenciation. l’immunophénotypage représente un élément clé du diagnostic pour affirmer l’appartenance au lignage lymphoïde T et le caractère immature de la population pathologique. Il souligne également l’hétérogénéité biologique de ces pathologies par l’identification de différents stades de différenciation. Toutefois, malgré de multiples tentatives de classification, l’intérêt clinique de la classification immunophénotypique diagnostique des LAL-T demeure limité. l’absence de valeur pronostique significative, écrasée par ailleurs par les marqueurs moléculaires reflétant davantage la biologie de l’hémopathie que son simple phénotype, en est le principal motif. Il en résulte que l’accumulation de systèmes de classification distincts et non complémentaires a rendu confuse la caractérisation phénotypique d’une LAL-T au diagnostic. Dans cet article, nous proposons de redéfinir le rationnel des différentes classifications qui ont été proposées au fil des dernières décennies, et de délimiter les informations qu’il convient de rapporter dans un compte rendu d’immunophénotypage clinique de LAL-T. Nous mettrons en lumière une perspective sur l’intérêt nouveau que représente l’immunophénotypage des LAL-T, en particulier en situation de rechute, par l’identification de biomarqueurs et cibles thérapeutiques.</div></div><div><h3>Abstract</h3><div>T-cell acute lymphoblastic leukemias (T-ALL) constitute a heterogeneous group of immature lymphoid hematologic disorders characterized by the clonal expansion of T precursor cells blocked in their differentiation progression. Immunophenotyping is a key element in the diagnosis to confirm the T-lymphoid lineage and the immature nature of the pathological population. It also highlights the biological heterogeneity of these diseases by identifying various stages of differentiation. However, despite multiple attempts at classification, the clinical relevance of immunophenotypic classification in T-ALL remains limited. The main reason is the lack of significant prognostic value, overshadowed by molecular markers that better reflect the biology of the disease rather than its simple phenotype. As a result, the accumulation of distinct and non-complementary classification systems has made the phenotypic characterization of T-ALL at diagnosis confusing. In this article, we aim to redefine the rationale behind the different classifications proposed over recent decades and outline the essential information to report in a clinical T-ALL immunophenotyping report. We will emphasize the renewed interest in immunophenotyping T-ALL, particularly in relapse situations, through the identification of biomarkers and therapeutic targets.</div></div>","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 572","pages":"Pages 20-27"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La Bretagne frappée par la méningite B","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76358-3","DOIUrl":"10.1016/S1773-035X(25)76358-3","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 572","pages":"Page 8"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virus HTLV-1 et leucémie-lymphome à cellules T de l’adulte (ATLL)","authors":"Charlotte Holuigue ,&nbsp;Véronique Baccini","doi":"10.1016/S1773-035X(25)76378-9","DOIUrl":"10.1016/S1773-035X(25)76378-9","url":null,"abstract":"<div><h3>Résumé</h3><div>Le virus T-lymphotrope humain de type 1 (HTLV-1 pour <em>HumanT-lymphotropic virus type 1)</em> est un virus qui constitue un enjeu de santé publique dans ses zones d’endémie telles que le Japon, les Caraïbes, l’Amérique du Sud et l’Afrique subsaharienne. Selon l’institut Pasteur, le risque cumulé de développer une de ses complications telles que la leucémie-lymphome à cellules T de l’adulte (ATLL pour <em>Adult T-cell leukemia/lymphoma)</em> ou la myélopathie/paraparésie spastique tropicale (TSP/HAM <em>pour Tropical spastic paraparesis/HTLV-I Associated Myelopathy)</em> est estimé entre 2 et 8%. L’ATLL est une hémopathie agressive à cellules T de pronostic très défavorable. Elle survient généralement vingt à trente ans après l’infection par le virus.</div><div>Cette revue de littérature vise à éclairer une pathologie méconnue et probablement sous-estimée. l’objectif est de fournir un rappel sur cette affection, en mettant en avant les aspects épidémiologiques, cliniques, diagnostiques et thérapeutiques afin de mieux sensibiliser et informer. Toutefois, les données actuelles restent insuffisantes, soulignant le besoin d’études complémentaires pour développer de nouvelles approches, notamment dans la prédiction de la survenue des complications.</div></div><div><h3>Abstract</h3><div>Human T-lymphotropic virus type 1 (HTLV-1) is a public health issue in endemic areas such as Japan, the Caribbean, South America and sub-Saharan Africa. According to the Institut Pasteur, the cumulative risk of developing one of the complications, such as adult T-cell leukemia/lymphoma (ATLL) or tropical spastic myelopathy/paraparesis (TSP/HAM), is estimated at between 2% and 8%. ATLL is a highly aggressive T-cell hemopathy with a poor prognosis. It generally occurs 20 to 30 years after infection by the virus.</div><div>The objective is to provide an overview of this disease, highlighting its epidemio-logical, clinical, diagnostic, and therapeutic aspects in order to raise awareness and provide information. However, current data remain insufficient, underlining the need for further studies to develop new approaches, in particular, in the prediction of the occurrence of complications.</div></div>","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 572","pages":"Pages 53-61"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Un invité s’incruste après un repas à base de poisson cru","authors":"Estelle Fleuriot ,&nbsp;Emeline Banh ,&nbsp;Sandra Le Mener ,&nbsp;Sébastien Larréché","doi":"10.1016/S1773-035X(25)76382-0","DOIUrl":"10.1016/S1773-035X(25)76382-0","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 572","pages":"Pages 79-80"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sciences, femmes, égalité…ou pas","authors":"Céline Beauvillain","doi":"10.1016/S1773-035X(25)76353-4","DOIUrl":"10.1016/S1773-035X(25)76353-4","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 572","pages":"Page 1"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fièvre jaune : une petite dose de vaccin suffit","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(25)76360-1","DOIUrl":"10.1016/S1773-035X(25)76360-1","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2025 572","pages":"Page 9"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}