Revue francophone des laboratoires : RFL最新文献

{"title":"Traitement antiviral et incidence de cardiopathies… en présence de facteurs de risque","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(24)00339-3","DOIUrl":"10.1016/S1773-035X(24)00339-3","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2024 566","pages":"Page 5"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascularites immunologiques des petits et moyens vaisseaux : physiopathologie et diagnostic biologique","authors":"Marie-Nathalie Kolopp Sarda , Chantal Dumestre-Pérard , Giovanna Clavarino","doi":"10.1016/S1773-035X(24)00360-5","DOIUrl":"10.1016/S1773-035X(24)00360-5","url":null,"abstract":"<div><h3>Résumé</h3><div>Les vascularites sont définies par une inflammation des endothéliums vasculaires, elles sont rares et de diagnostic difficile. Cet article n’évoquera que les vascularites primitives non infectieuses, comme cela est fait dans la nomenclature internationale de Chapel Hill dont la deuxième version impose le remplacement des dénominations éponymes des maladies par des expressions en lien avec leur mécanisme physiopathologique ou leurs caractéristiques histologiques.</div><div>Cette nomenclature des vascularites prend en compte la taille des vaisseaux et les mécanismes physiopathologiques qui, dans l’atteinte des petits et moyens vaisseaux, sont des mécanismes immunologiques. Il s’agit d’une part des vascularites à dépôts de complexes immuns, comprenant les vascularites cryoglobulinémiques, les vascularites à dépôts d’IgA, les vascularites urticariennes hypocomplémentémiques (maladie de McDuffie) et les vascularites à Acs anti-membrane basale glomérulaire (maladie de Goodpasture), et d’autre part des vascularites à Acs anticytoplasme des polynucléaires neutrophiles (ANCA pour <em>Anti-Neutrophil Cytoplasmic Antibodies</em>), qui comprennent la granulomatose avec polyangéite (ex-syndrome de Wegener), la granulomatose à éosinophiles avec polyangéite (ex-syndrome de Churg et Strauss) et la polyangéite microscopique. Dans cet article, les mécanismes physiopathologiques de ces vascularites immunologiques et les outils biologiques seront développés, permettant aux biologistes de participer au diagnostic de ces maladies rares et fréquemment sévères.</div></div><div><h3>Abstract</h3><div>Vasculitis is defined by inflammation of the vascular endothelium, it is rare and difficult to diagnose. This article will only discuss primary non-infectious vasculitis, as is done in the international nomenclature of Chapel Hill, the second version of which aimed to replace the eponymous names of diseases with expressions related to their pathophysiological mechanism or their histological characteristics. This nomenclature of vasculitis takes into account the size of the vessels and the pathophysiological mechanisms which, in the involvement of small and medium-sized vessels, are immunological mechanisms. These are first, vasculitis with immune complex deposition, including cryoglobulinemic vasculitis, vasculitis with IgA deposits, hypocomplementemic urticarial vasculitis (McDuffie’s disease) and vasculitis with anti-glomerular basement membrane Abs (Goodpasture’s disease), and second, vasculitis with anti-neutrophil cytoplasmic Abs (ANCA), including granulomatosis with polyangiitis (formerly Wegener’s syndrome), eosinophilic granulomatosis with polyangiitis (formerly Churg-Strauss syndrome) and microscopic polyangiitis. In this article, the pathophysiological mechanisms of these immunological vasculitides and the biological diagnostic tools will be developed, allowing biologists to participate in the diagnosis of these rare and frequently severe di","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2024 566","pages":"Pages 47-55"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142577915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Les dentelles de Montmirail à l'électrophorèse","authors":"Elisa Orlhac, Marie Nathalie, Kolopp Sarda","doi":"10.1016/S1773-035X(24)00364-2","DOIUrl":"10.1016/S1773-035X(24)00364-2","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2024 566","pages":"Pages 79-80"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Le plan stratégique de l’OMS pour contenir une épidémie d’allure mondiale","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(24)00345-9","DOIUrl":"10.1016/S1773-035X(24)00345-9","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2024 566","pages":"Page 9"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Syndrome du QT long, y-a-t-il un risque lié à une activité physique vigoureuse ?","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(24)00341-1","DOIUrl":"10.1016/S1773-035X(24)00341-1","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2024 566","pages":"Page 6"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rôle du laboratoire dans le diagnostic d’une onychomycose : méthodes et interprétation","authors":"Dominique Chabasse","doi":"10.1016/S1773-035X(24)00359-9","DOIUrl":"10.1016/S1773-035X(24)00359-9","url":null,"abstract":"<div><h3>Résumé</h3><div>Les onychomycoses ne représentent pas plus de 50 % de l’ensemble des pathologies unguéales. Les dermatophytes anthropophiles ( <em>Trichophyton rubrum</em> et <em>T. interdigitale</em>) sont les principaux agents rencontrés au niveau des pieds. Les levures du genre <em>Candida</em> ( <em>Candida albicans</em>, <em>Candida parapsilosis</em>, etc.) et parfois <em>Trichosporon</em> prédominent aux ongles des mains où l’atteinte unguéale peut s’associer à un périonyxis. D’autres espèces de champignons filamenteux, ayant une affinité particulière pour la kératine, et donnant des lésions proches des dermatophytes (appelées “pseudodermatophytes”) appartiennent au genre <em>Neoscytalidium</em> issues des régions tropicales et subtropicales, et <em>Arachnomyces nodosetosus</em> anciennement <em>Onychocola canadensis</em>, espèce kératinophile issue de pays tempérés ou froids impliqué surtout dans les onyxis des pieds de sujets âgés. Parmi les moisissures environnementales pouvant parfois parasiter l’ongle se trouvent principalement des espèces appartenant aux genres <em>Scopulariopsis</em>, <em>Aspergillus</em> et <em>Fusarium</em>, leur pouvoir pathogène n’est pas évident. Le rôle du laboratoire est justement, en plus de l’identification de l’espèce isolée, de démontrer que le champignon issu des prélèvements d’un ongle pathologique est bien le pathogène en cause.</div></div><div><h3>Abstract</h3><div>Onychomycosis does not represent more than 50% of all nail pathologies. Anthropophilic dermatophytes ( <em>Trichophyton rubrum</em> and <em>T. interdigitale</em>) are the main agents encountered on feet. Yeasts of the genus <em>Trichosporon</em> and <em>Candida</em> ( <em>Candida albicans</em>, <em>Candida parapsilosis</em>, etc.) predominate on fingernails where nail damage can be associated with perionyxis. Other filamentous species, called “pseudodermatophytes”, have a particular affinity for keratin, such as dermatophytes. These keratinophilic species belong to the genus <em>Neoscytalidium</em> from tropical and subtropical regions, and Arachnomyces nodosetosus from temperate or cold countries, mainly involved in onyxis on the feet of elderly people. Among the environmental molds that can sometimes parasitize nails, there are mainly species belonging to the genera <em>Scopulariopsis</em>, <em>Aspergillus</em> and <em>Fusarium</em>, their pathogenic power must however be clearly defined. The role of the Laboratory is precisely to identify the species in question, and to demonstrate that the fungus isolated from samples of a pathological nail is indeed the pathogen in question.</div></div>","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2024 566","pages":"Pages 34-46"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brève: Suspension du ballon anti-obésité à la demande de l’ANSM","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(24)00348-4","DOIUrl":"10.1016/S1773-035X(24)00348-4","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2024 566","pages":"Page 11"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ehpad, nouvelles alertes sur les finances et l'avenir des établissements pour nos anciens","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(24)00294-6","DOIUrl":"10.1016/S1773-035X(24)00294-6","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2024 565","pages":"Page 19"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brève : Une entreprise mondiale pour des vaccins anti-VIH","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(24)00277-6","DOIUrl":"10.1016/S1773-035X(24)00277-6","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2024 565","pages":"Page 8"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprendre pour mieux traiter la toxoplasmose cérébrale persistante :","authors":"Jean-Marie Manus","doi":"10.1016/S1773-035X(24)00286-7","DOIUrl":"10.1016/S1773-035X(24)00286-7","url":null,"abstract":"","PeriodicalId":74728,"journal":{"name":"Revue francophone des laboratoires : RFL","volume":"2024 565","pages":"Page 14"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142432005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}