Research in health science最新文献

{"title":"Based on the Molecular Mechanism of CiteSpace Sanqi Total Saponin and the Prevention and Treatment of Renal Fibrosis, Hot Spot Visualization Analysis","authors":"Xuanxian Li, Fengyi Li, Jinwei Luo, Chenglin Li, Jiajie Liu, Jingzhao Yuan, Feixiang Zeng, Zhuocong Zhong","doi":"10.22158/rhs.v9n2p9","DOIUrl":"https://doi.org/10.22158/rhs.v9n2p9","url":null,"abstract":"This study aims to study the current situation, hot spots and development trends of Sanqi total saponins in the prevention and treatment of renal fibrosis through a visual map, in order to provide a direction and trend for the research of traditional Chinese medicine on the prevention and treatment of renal fibrosis. Method: By using CiteSpace visualization software, the relevant literature on the use of Sanqi total saponins in the CNKI database for the treatment of renal fibrosis was visually analyzed, including posting trends, authors, institutions and keywords, and the corresponding knowledge map was generated. Results: From 2005 to 2022, a total of 1,533 documents were included in the research results. From 2008 to 2017, an average of 99 articles were published every year, accounting for 67.5% of the total number of articles published. Among them, the number of articles published in 2010 and 2013 reached 114, the highest in previous years. At the same time, Yang Min is the author who has published the most articles, with a total of 29 papers. Beijing University of Traditional Chinese Medicine is the main research institution in this field. Through cluster analysis of research hotspots, ten clusters were obtained, including rats, left ventricular reconstruction, oxidative stress, drug interaction, astragaloside, apoptosis, matrix metalloproteinase-9,oleoside, lipopolysaccharide, atherosclerosis, etc. Future research focuses include oxidative stress, autophagy process, Sanqi total saponins, inflammatory response, cell proliferation and apoptosis, and pharmacokinetics. Conclusion: The knowledge map reveals the research status and research hotspots of Sanqi total saponins in the prevention and treatment of renal fibrosis, including oxidative stress, inflammation, cell proliferation and apoptosis, which will become the focus of research on the prevention and treatment of renal fibrosis in traditional Chinese medicine in the future. However, the collaboration between research authors and scientific research institutions lacks closeness, lacks core authors, and has not yet formed an influential research organization. The depth and breadth of research need to be further enhanced.","PeriodicalId":74678,"journal":{"name":"Research in health science","volume":"74 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140655346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review of Status Quo of Post Management of TCM Specialist Nurses in China","authors":"Hengyu Zhang, Haiyun Gai, Minghui Ma, Meng Li, Yingying Zhou","doi":"10.22158/rhs.v9n2p1","DOIUrl":"https://doi.org/10.22158/rhs.v9n2p1","url":null,"abstract":"It summarized the current situation of post-management of TCM specialist nurses in China and mainly introduced the current situation of post-management of TCM specialist nurses in China from the aspects of post setting, post responsibilities, post hierarchy, and performance evaluation.","PeriodicalId":74678,"journal":{"name":"Research in health science","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140690025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Historical Review and Prospect of the Rights of Ethnic Minority Children in Western China","authors":"Yan Wang","doi":"10.22158/rhs.v9n1p49","DOIUrl":"https://doi.org/10.22158/rhs.v9n1p49","url":null,"abstract":"Children are the hope of the country in the future. People have been concerned about the healthy growth of children, pay attention to welfare undertakings, and make practical efforts for children's own interests and long-term development. People attach great importance to this, in order to protect the healthy growth of children, constantly children's health protection work. The author mainly discusses the historical review and prospect of children's health from four aspects: improving the protection of child welfare, improving children's security system, strengthening children's family responsibility and establishing children's self-protection consciousness.","PeriodicalId":74678,"journal":{"name":"Research in health science","volume":"99 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140713668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Low-Quality Embryo on Adverse Obstetric and Perinatal Outcomes","authors":"Xianju Huang, Beibei Bi, Xinle Lu, Ludan Chao, Qiuying Cui","doi":"10.22158/rhs.v9n1p37","DOIUrl":"https://doi.org/10.22158/rhs.v9n1p37","url":null,"abstract":"Background: This retrospective study focused on whether low-quality embryos have the risk on perinatal and obstetric outcomes. Methods: This study enrolled 600 women undergoing fresh embryos transfer (ET) cycles between June 2019 and December 2022. The patients were stratified into two groups, high-quality embryo group and low-quality embryo group. In both groups, the perinatal and obstetric outcomes were the primary outcomes. Moreover, we conducted a multi-variable logistic regression analysis, where additional possible confounding factors were controlled, to determine how diverse embryo qualities affected the primary outcomes. Results: The results showed that compared with the low-quality group, the high-quality group showed increased clinical pregnancy (63.33% vs 26.33%) as well as a higher number of live birth rates (52.67% vs 18.33%) (P＜0.001). There were no statistically significant differences in unfavorable perinatal and obstetric outcomes between high- and low-quality groups (p＞0.05). Similarly, the transfer of blastocysts developing from high-quality embryos led to increased clinical pregnancy rates (84.50% vs 48.05%, p<0.001) and live birth rates (74.64% vs 38.96%, p<0.001). Transfer of blastocysts developing from low-quality embryos did not impact the unfavorable perinatal or obstetric outcomes. The logistic regression analysis showed that low-quality could not increase the unfavorable perinatal or obstetric outcomes. Conclusion: In summary, low-quality ET does not increase the risk of unfavorable perinatal or obstetric outcomes. Overall, compared to low-quality embryos, the transfer of high-quality embryos increases the clinical pregnancy and live birth rates.","PeriodicalId":74678,"journal":{"name":"Research in health science","volume":"80 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140487421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of Five-tone Therapy Combined with Acupressure in Colonoscopy","authors":"Ran Yi","doi":"10.22158/rhs.v9n1p30","DOIUrl":"https://doi.org/10.22158/rhs.v9n1p30","url":null,"abstract":"Colonoscopy is an important method for the diagnosis of digestive tract diseases, especially in the diagnosis and treatment of colorectal cancer has a key role. But as an invasive medical procedure, colonoscopy can lead to more severe pain in patients, and even cause intestinal inflation, resulting in patients with abdominal distension, intestinal spasms and other discomfort. Therefore, relieving the pain of patients during colonoscopy has become an important issue that medical staff must pay attention to. In this context, this paper carries out research, and uses five-tone therapy combined with acupressure diagnosis and treatment mode as an effective method to solve the pain problem of colonoscopy. Through analyzing its intervention process and implementation methods, the diagnosis and treatment effects are further analyzed.","PeriodicalId":74678,"journal":{"name":"Research in health science","volume":" 1165","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139617233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Nurse-led Educational Interventions on Glycemic Control and Self-care Behaviors of Type 2 Diabetics: A Systematic Review","authors":"Yi Shi, Xueqing Liang","doi":"10.22158/rhs.v9n1p1","DOIUrl":"https://doi.org/10.22158/rhs.v9n1p1","url":null,"abstract":"Background: Blood glucose control is challenging for patients with diabetes and is often associated with self-care behaviors. The effectiveness of nurse-led educational interventions for glycemic control and self-care behaviors in patients with type 2 diabetes is unclear.Objective: To determine effectiveness of nurse-led educational intervention on glycemic control and self-care behaviors in patients with type 2 diabetes.Design: Mixed methods systematic review.Data Sources: A comprehensive search in Medline, CINAHL and Scopus was conducted in February 2023 to identify peer-reviewed papers published between 2003 and 2023.Review Methods: The review was guided by the Joanna Briggs Institute systematic review manual. Data were extracted and assessed by two evaluators using a standardized checklist. Due to the high level of heterogeneity between studies, the data were analyzed using Popay et al.'s (2006) conduct of narrative synthesis in systematic reviews.Results: Ten randomized controlled trials met the inclusion criteria. Studies described nurse-led educational interventions delivered either face-to-face or online. The outcomes of the educational interventions and the measurement tools used were diverse, with many studies reporting attrition. Most studies reported that nurse-led educational interventions improved outcomes for patients with type 2 diabetes.Conclusions: The evidence identifies that nurse-led educational interventions are effective for glycemic control and self-care behaviors in patients with type 2 diabetes. This review demonstrates evidence of approaches that could inform future practice and research to support all adult populations of patients with type 2 diabetes to improve glucose control and self-care behaviors. Future research would benefit from well-designed clinical trials that use common outcome measures to provide more information about the effectiveness as well as the sustainability of such interventions.","PeriodicalId":74678,"journal":{"name":"Research in health science","volume":"37 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138994226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Polyvalent Staphylococcus Vaccine on the Gene Expression of IL-8, IFN-γ, IL-1R and Phagocytes in Mice Spleen","authors":"Meng Zhou, Chenfei Qu, Zhu Lei, Chunhua Bi, Xiao Jiang, Ting Liu, Qi’an Yue","doi":"10.22158/rhs.v8n4p95","DOIUrl":"https://doi.org/10.22158/rhs.v8n4p95","url":null,"abstract":"Objectives: To study the effect of Polyvalent staphylococcus vaccine on cellular immune function in mice. Methods: Forty SD kunming species of mice were randomly divided into low dose group (500 million/ml bacteria), middle dose group (1 billion/ml bacteria), high dose group (2 billion/ml bacteria) and control group, Mice were immunized with different doses of Polyvalent staphylococcus vaccine. The expression of IL-8, IFN - γ and IL-1R genes in spleen tissues of mice in different doses of experimental group and control group were detected by RT-PCR, and the phagocytic effect of phagocytes in abdominal cavity of mice was detected by abdominal smear Results: Compared with the normal control group, the expression level of IL-8, IFN - γ, IL-1R gene and phagocytic function of spleen in the experimental group were significantly higher than those in the control group (P < 0.01), the effect in the middle dose group were the best. Conclusion: Polyvalent staphylococcus vaccine can significantly improve the expression level of IL-8, IFN - γ, IL-1R gene in mouse spleen, and enhance the phagocytic function of phagocytes, and its effect showed dose-dependent manner.","PeriodicalId":74678,"journal":{"name":"Research in health science","volume":"49 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138605232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Interaction between Histone Lysine Methyltransferase GLP and EZH2","authors":"Xinle Lu, Ludan Chao, Xianju Huang","doi":"10.22158/rhs.v8n4p72","DOIUrl":"https://doi.org/10.22158/rhs.v8n4p72","url":null,"abstract":"Recent studies have implicated that H3K9 lysine methyltransferases (KMTs) and polycomb repressive complex2 (PRC2) act in a cross-talk. However, a connection between GLP, one of the well-known H3K9 KMTs and the EZH2, one of the core members of PRC2, has not been established. Here we not only demonstrated that there was interaction between the GLP and the EZH2 proteins in vivo, but also provided evidence that the activity of EZH2 was effected by down-regulation of GLP. In light of these observations, western blotting, co-immunoprecipitation and qRT-PCR were performed to explore in GLP siRNA KGN cells. The specific interaction between GLP and EZH2 was demonstrated with co-immunoprecipitation. Our results also indicate that the decreased level of GLP participate in the modulation of EZH2 function in vivo.Taken together, our findings identified that an unanticipated interplay between the two histone lysine methyltransferases, which is implicated in regulating of a subset of developmental genes.","PeriodicalId":74678,"journal":{"name":"Research in health science","volume":"122 30","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138606857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CiteSpace Visual Analysis of Community Pharmacy Services in China: Bridging Local Insights and Global Trends","authors":"Yanping Li, Shangjie Yang, Yan Mao, Lihu Zhang","doi":"10.22158/rhs.v8n4p82","DOIUrl":"https://doi.org/10.22158/rhs.v8n4p82","url":null,"abstract":"Purpose: This research traces the history of pharmacy services research in Chinese pharmacies over the past twenty years and attempts to identify key trends and hotspots consistent with global practices. Methodology: From January 2002 to December 2022, we leveraged databases such as CNKI, VIP, and Wanfang and deployed CiteSpace 5.8.R3 to visualize publication trends, authorship, and institutional contributions within the field. Results: Our synthesis highlights critical developments in drug safety monitoring, prescription management, pharmacoeconomics, and public health education and highlights the leadership of respected researchers and institutions. Conclusion: The “Internet+” paradigm is identified as an important catalyst for pharmacy services innovation, with implications that extend beyond China and suggest models for international adaptation and strategy development.","PeriodicalId":74678,"journal":{"name":"Research in health science","volume":"74 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138606384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Evaluation of Healthcare Associated Infection Surveillance System","authors":"Yang Zhou, Genlin Yang, Ping Shao, Yan Cui","doi":"10.22158/rhs.v8n4p66","DOIUrl":"https://doi.org/10.22158/rhs.v8n4p66","url":null,"abstract":"Background & objectives: The electronic surveillance system has been applied in healthcare associated infection surveillance. We conducted an evaluation of the real-time healthcare associated infection surveillance system (RT-HAISS) to understand the early warning effect. Methods: We evaluated our RT-HAISS on a dataset of 29074 patients at the Wuxi traditional Chinese medicine (TCM) hospital in 2020, encompassing sensitivity, specificity, positive predictive value, negative predictive value, Youden index and false alarm rate.Results: 466 HAIs were confirmed in this hospital in 2020, The RT-HAISS warned the monitors a total of 1715 cases, with 2040 early warning entries and 1736 false alarm entries. The sensitivity and the specificity were 65.24% and 95.74%, respectively. The Youden index was 0.62. In addition, the positive predictive value was 14.90%, and the negative predictive value was 83.86%, with 85.10% of false alarm rate.Conclusion: The RT-HAISS is an important technical mean for healthcare associated infection surveillance, it’s necessary to further explore the improvement of real-time surveillance system.","PeriodicalId":74678,"journal":{"name":"Research in health science","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139214450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}