{"title":"How can membrane lipid constituency be manipulated to produce liposomes with desired functions?","authors":"T Issler, S Lisowski, K Farzi, E J Prenner","doi":"10.1080/17435889.2025.2469485","DOIUrl":"10.1080/17435889.2025.2469485","url":null,"abstract":"","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biomaterials-mediated biomineralization for tumor blockade therapy.","authors":"Chao Sun, Shuqiang Li, Jianxun Ding","doi":"10.1080/17435889.2025.2451018","DOIUrl":"10.1080/17435889.2025.2451018","url":null,"abstract":"<p><p>Recent advancements in tumor therapy have underscored the potential of biomaterials-mediated biomineralization for tumor blockade. By precisely regulating biomineralization and constructing nanomineralized structures at the cellular level, this therapy achieves multi-dimensional targeted inhibition of tumors. Mineralized precursor molecules are engineered to selectively recognize and bind to proteins on the tumor cell membrane, obstructing signal transduction. Biomineralized materials directly target the tumor cell membrane, disrupting its biological functions and inducing cell apoptosis. Additionally, these materials infiltrate the mitochondria of tumor cells, disrupting energy metabolism through mineralization and significantly impairing tumor viability. This biomaterials-mediated approach enhances treatment precision and efficacy while mitigating side effects, offering a unique approach to tumor therapy.</p>","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"417-425"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Global research trends on nanotechnology and colorectal cancer: a two-decade analysis.","authors":"Xinyu Mao, Xinhao Li, Shiwei Liu, Hui Dong, Weilu Jia, Wenjing Xu, Xia Wu, Yewei Zhang","doi":"10.1080/17435889.2025.2452833","DOIUrl":"10.1080/17435889.2025.2452833","url":null,"abstract":"<p><strong>Introduction: </strong>Colorectal cancer (CRC) remains a serious threat to humans worldwide. In this study, we used bibliometric analysis of the scientific literature to assess the trends and prospects of nanotechnology applications in CRC.</p><p><strong>Materials and methods: </strong>We used the Web of Science Core Collection database to screen relevant publications on nanotechnology and CRC from 2004 to 2023 based on the inclusion criteria. Bibliometric analyses were performed on all selected publication and citation data. Visual analysis using VOSviewer and CiteSpace intuitively reflected the hotspots in this field.</p><p><strong>Results: </strong>In total, 2040 publications on nanotechnology in CRC were identified for this two-decade analysis. China (443, 29.14%) and the USA (199, 13.09%) were the top two most productive countries, and Sichuan University was the most prolific institution. The most influential journal was the International Journal of Nanomedicine. The author with the most papers was Li L. \"Nanoparticles,\" \"drug delivery,\" and \"CRC\" were the most common keywords. Green synthesis and gold nanoparticles were peripheral, incompletely developed topics.</p><p><strong>Conclusion: </strong>This study provides a comprehensive overview of nanomaterials in CRC as clinical medicine, enriching the body of evidence in this field.</p>","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"343-354"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deng-Guang Yu, Wei He, Cui He, Hui Liu, Haisong Yang
{"title":"Versatility of electrospun Janus wound dressings.","authors":"Deng-Guang Yu, Wei He, Cui He, Hui Liu, Haisong Yang","doi":"10.1080/17435889.2024.2446139","DOIUrl":"10.1080/17435889.2024.2446139","url":null,"abstract":"<p><p>Electrospun nanofibers produced through single-fluid blending processes have successfully demonstrated their potential as highly effective wound dressings. However, electrospun Janus nanofibers, in which various chambers can be designed to load different active pharmaceutical ingredients into different polymeric matrices, are further exhibiting their versatility for promoting wound healing. This commentary declares that wound dressings always need multiple functional performances to promote wound healing. Janus nanofibers have their unique advantages, with different parts interacting with their environments, thereby providing a versatile platform for developing novel wound dressings. Two recent examples, each with a different preparation strategy for developing novel wound dressings, are discussed, and the promising future of Janus nanofibers in wound dressing applications is highlighted.</p>","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"271-278"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11852743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The potential of nanoparticle-based contrast agents in the diagnosis of neurodegenerative pathologies.","authors":"Marina Ulanova","doi":"10.1080/17435889.2024.2428588","DOIUrl":"10.1080/17435889.2024.2428588","url":null,"abstract":"","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"247-249"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11792784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jing Zang, Fang Yin, Ziyuan Liu, Fengqian Li, Yang Zhang
{"title":"Bacteria-tumor symbiosis destructible novel nanocatalysis drug delivery systems for effective tumor therapy.","authors":"Jing Zang, Fang Yin, Ziyuan Liu, Fengqian Li, Yang Zhang","doi":"10.1080/17435889.2024.2443388","DOIUrl":"10.1080/17435889.2024.2443388","url":null,"abstract":"<p><p>Colorectal cancer (CRC) is a significant threat to human health. The dynamic equilibrium between probiotics and pathogenic bacteria within the gut microbiota is crucial in mitigating the risk of CRC. An overgrowth of harmful microorganisms in the gastrointestinal tract can result in an excessive accumulation of bacterial toxins and carcinogenic metabolites, thereby disrupting the delicate balance of the microbiota. This disruption may lead to alterations in microbial composition, impairment of mucosal barrier function, potential promotion of abnormal cell proliferation, and ultimately contribute to the progression of CRC. Recently, research has indicated that intestinal presence of <i>Fusobacterium nucleatum</i> (Fn) significantly influences the onset, progression, and metastasis of CRC. Consequently, disrupting the interaction between CRC cells and Fn presents a promising strategy against CRC. Nanomaterials have been extensively utilized in cancer therapy and bacterial infection control, demonstrating substantial potential in treating bacteria-associated tumors. This review begins by elucidating the mechanisms of gut microbiota and the occurrence and progression of CRC, with a particular emphasis on clarifying the intricate relationship between Fn and CRC. Subsequently, we highlight strategies that utilize nanomaterials to disrupt the association between Fn and CRC. Overall, this review offers valuable insight and guidance for leveraging nanomaterials in CRC therapy.</p>","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":"20 3","pages":"305-318"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11792809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Galli, Stefano Cozzi, Francesca Granucci, Laura Marongiu
{"title":"Engineering immunity with nanoparticles: highlights from recent research on transplant rejection therapy.","authors":"Marco Galli, Stefano Cozzi, Francesca Granucci, Laura Marongiu","doi":"10.1080/17435889.2024.2443386","DOIUrl":"10.1080/17435889.2024.2443386","url":null,"abstract":"","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"339-342"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}