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Recent advances in nanotherapeutics for HIV-associated neurocognitive disorders and substance use disorders.
Nanomedicine (London, England) Pub Date : 2025-03-01 Epub Date: 2025-02-18 DOI: 10.1080/17435889.2025.2461984
Christia Lomas, Ravi Chandra Dubey, Gabriela Perez-Alvarez, Yesenia Lopez Hernandez, Aorzala Atmar, Adriana Yndart Arias, Atul Vashist, Saurabh Aggarwal, Pandiaraj Manickam, Madepalli Krishnappa Lakshmana, Arti Vashist
{"title":"Recent advances in nanotherapeutics for HIV-associated neurocognitive disorders and substance use disorders.","authors":"Christia Lomas, Ravi Chandra Dubey, Gabriela Perez-Alvarez, Yesenia Lopez Hernandez, Aorzala Atmar, Adriana Yndart Arias, Atul Vashist, Saurabh Aggarwal, Pandiaraj Manickam, Madepalli Krishnappa Lakshmana, Arti Vashist","doi":"10.1080/17435889.2025.2461984","DOIUrl":"10.1080/17435889.2025.2461984","url":null,"abstract":"<p><p>Substance use disorders (SUD) and HIV-associated neurocognitive disorders (HAND) work synergistically as a significant cause of cognitive decline in adults and adolescents globally. Current therapies continue to be limited due to difficulties crossing the blood-brain barrier (BBB) leading to limited precision and effectiveness, neurotoxicity, and lack of co-treatment options for both HAND and SUD. Nanoparticle-based therapeutics have several advantages over conventional therapies including more precise targeting, the ability to cross the BBB, and high biocompatibility which decreases toxicity and optimizes sustainability. These advantages extend to other neurological disorders such as Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS). This review summarizes recent advances in nanotechnology for application to HAND, SUD, and co-treatment, as well as other neurological disorders. This review also highlights the potential challenges these therapies face in clinical translation and long-term safety.</p>","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"603-619"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11902879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toward a cure for type 1 diabetes: the innovative potential of Phosphatidylserine-rich liposomes.
Nanomedicine (London, England) Pub Date : 2025-02-28 DOI: 10.1080/17435889.2025.2473872
Bruna Barneda-Zahonero, Lidia Almenara-Fuentes, David Perna-Barrull, Marta Vives-Pi
{"title":"Toward a cure for type 1 diabetes: the innovative potential of Phosphatidylserine-rich liposomes.","authors":"Bruna Barneda-Zahonero, Lidia Almenara-Fuentes, David Perna-Barrull, Marta Vives-Pi","doi":"10.1080/17435889.2025.2473872","DOIUrl":"https://doi.org/10.1080/17435889.2025.2473872","url":null,"abstract":"","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Realizing the potential of nanomedicines to treat breast cancer liver metastasis.
Nanomedicine (London, England) Pub Date : 2025-02-27 DOI: 10.1080/17435889.2025.2469491
Biana Godin, Hermann B Frieboes
{"title":"Realizing the potential of nanomedicines to treat breast cancer liver metastasis.","authors":"Biana Godin, Hermann B Frieboes","doi":"10.1080/17435889.2025.2469491","DOIUrl":"https://doi.org/10.1080/17435889.2025.2469491","url":null,"abstract":"","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How can membrane lipid constituency be manipulated to produce liposomes with desired functions?
Nanomedicine (London, England) Pub Date : 2025-02-24 DOI: 10.1080/17435889.2025.2469485
T Issler, S Lisowski, K Farzi, E J Prenner
{"title":"How can membrane lipid constituency be manipulated to produce liposomes with desired functions?","authors":"T Issler, S Lisowski, K Farzi, E J Prenner","doi":"10.1080/17435889.2025.2469485","DOIUrl":"10.1080/17435889.2025.2469485","url":null,"abstract":"","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Self-assembling peptoid-based antimicrobial nanomaterials.
Nanomedicine (London, England) Pub Date : 2025-02-23 DOI: 10.1080/17435889.2025.2469482
Håvard Jenssen
{"title":"Self-assembling peptoid-based antimicrobial nanomaterials.","authors":"Håvard Jenssen","doi":"10.1080/17435889.2025.2469482","DOIUrl":"https://doi.org/10.1080/17435889.2025.2469482","url":null,"abstract":"","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The distinct properties of high-density lipoprotein nanoparticles as ocular drug delivery vehicles.
Nanomedicine (London, England) Pub Date : 2025-02-21 DOI: 10.1080/17435889.2025.2469489
Tatsuya Murakami, Haruka Kurita
{"title":"The distinct properties of high-density lipoprotein nanoparticles as ocular drug delivery vehicles.","authors":"Tatsuya Murakami, Haruka Kurita","doi":"10.1080/17435889.2025.2469489","DOIUrl":"https://doi.org/10.1080/17435889.2025.2469489","url":null,"abstract":"","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Next generation nanoparticle protein corona characterization methods.
Nanomedicine (London, England) Pub Date : 2025-02-06 DOI: 10.1080/17435889.2025.2460962
Wei He, Wen Wu, Yuanyuan Li, Qihui Liu, Ping Ren, Haiyan Liu, Fangfang Chen
{"title":"Next generation nanoparticle protein corona characterization methods.","authors":"Wei He, Wen Wu, Yuanyuan Li, Qihui Liu, Ping Ren, Haiyan Liu, Fangfang Chen","doi":"10.1080/17435889.2025.2460962","DOIUrl":"10.1080/17435889.2025.2460962","url":null,"abstract":"","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advantages of nanoencapsulation in the delivery of therapeutics for bone regeneration. 纳米封装在骨再生治疗药物输送方面的优势。
Nanomedicine (London, England) Pub Date : 2025-02-05 DOI: 10.1080/17435889.2025.2462518
Federica Banche-Niclot, Francesca Taraballi
{"title":"Advantages of nanoencapsulation in the delivery of therapeutics for bone regeneration.","authors":"Federica Banche-Niclot, Francesca Taraballi","doi":"10.1080/17435889.2025.2462518","DOIUrl":"https://doi.org/10.1080/17435889.2025.2462518","url":null,"abstract":"","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomaterials-mediated biomineralization for tumor blockade therapy. 生物材料介导的生物矿化用于肿瘤阻断治疗。
Nanomedicine (London, England) Pub Date : 2025-02-01 Epub Date: 2025-01-12 DOI: 10.1080/17435889.2025.2451018
Chao Sun, Shuqiang Li, Jianxun Ding
{"title":"Biomaterials-mediated biomineralization for tumor blockade therapy.","authors":"Chao Sun, Shuqiang Li, Jianxun Ding","doi":"10.1080/17435889.2025.2451018","DOIUrl":"10.1080/17435889.2025.2451018","url":null,"abstract":"<p><p>Recent advancements in tumor therapy have underscored the potential of biomaterials-mediated biomineralization for tumor blockade. By precisely regulating biomineralization and constructing nanomineralized structures at the cellular level, this therapy achieves multi-dimensional targeted inhibition of tumors. Mineralized precursor molecules are engineered to selectively recognize and bind to proteins on the tumor cell membrane, obstructing signal transduction. Biomineralized materials directly target the tumor cell membrane, disrupting its biological functions and inducing cell apoptosis. Additionally, these materials infiltrate the mitochondria of tumor cells, disrupting energy metabolism through mineralization and significantly impairing tumor viability. This biomaterials-mediated approach enhances treatment precision and efficacy while mitigating side effects, offering a unique approach to tumor therapy.</p>","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"417-425"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global research trends on nanotechnology and colorectal cancer: a two-decade analysis. 纳米技术和结直肠癌的全球研究趋势：二十年分析。
Nanomedicine (London, England) Pub Date : 2025-02-01 Epub Date: 2025-01-20 DOI: 10.1080/17435889.2025.2452833
Xinyu Mao, Xinhao Li, Shiwei Liu, Hui Dong, Weilu Jia, Wenjing Xu, Xia Wu, Yewei Zhang
{"title":"Global research trends on nanotechnology and colorectal cancer: a two-decade analysis.","authors":"Xinyu Mao, Xinhao Li, Shiwei Liu, Hui Dong, Weilu Jia, Wenjing Xu, Xia Wu, Yewei Zhang","doi":"10.1080/17435889.2025.2452833","DOIUrl":"10.1080/17435889.2025.2452833","url":null,"abstract":"<p><strong>Introduction: </strong>Colorectal cancer (CRC) remains a serious threat to humans worldwide. In this study, we used bibliometric analysis of the scientific literature to assess the trends and prospects of nanotechnology applications in CRC.</p><p><strong>Materials and methods: </strong>We used the Web of Science Core Collection database to screen relevant publications on nanotechnology and CRC from 2004 to 2023 based on the inclusion criteria. Bibliometric analyses were performed on all selected publication and citation data. Visual analysis using VOSviewer and CiteSpace intuitively reflected the hotspots in this field.</p><p><strong>Results: </strong>In total, 2040 publications on nanotechnology in CRC were identified for this two-decade analysis. China (443, 29.14%) and the USA (199, 13.09%) were the top two most productive countries, and Sichuan University was the most prolific institution. The most influential journal was the International Journal of Nanomedicine. The author with the most papers was Li L. \"Nanoparticles,\" \"drug delivery,\" and \"CRC\" were the most common keywords. Green synthesis and gold nanoparticles were peripheral, incompletely developed topics.</p><p><strong>Conclusion: </strong>This study provides a comprehensive overview of nanomaterials in CRC as clinical medicine, enriching the body of evidence in this field.</p>","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"343-354"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11812397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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