Nanomedicine (London, England)最新文献_第2页

Luminescent protein-gold compounds for nanomedicine. 纳米医学用发光蛋白金化合物。

IF 3.9

Nanomedicine (London, England) Pub Date : 2025-10-01 Epub Date: 2025-07-01 DOI: 10.1080/17435889.2025.2525748

Shunji Egusa

引用次数: 0

Rewiring cell identity in vivo: the emerging role of extracellular vesicles. 体内细胞身份重组：细胞外囊泡的新作用。

IF 3.9

Nanomedicine (London, England) Pub Date : 2025-10-01 Epub Date: 2025-06-17 DOI: 10.1080/17435889.2025.2520151

Ana I Salazar Puerta, Daniel Gallego-Perez

引用次数: 0

Storage stability of cowpea mosaic virus cancer drug candidate - a two-year update. 豇豆花叶病毒抗癌候选药物的储存稳定性-两年更新。

IF 3.9

Nanomedicine (London, England) Pub Date : 2025-10-01 Epub Date: 2025-08-09 DOI: 10.1080/17435889.2025.2544522

Andrea Simms, Narek Minasov, Nicole F Steinmetz

引用次数: 0

Nanotechnology-based topical treatments for androgenic alopecia. 基于纳米技术的雄激素性脱发局部治疗。

IF 3.9

Nanomedicine (London, England) Pub Date : 2025-10-01 Epub Date: 2025-06-27 DOI: 10.1080/17435889.2025.2523732

Jayanaraian F Martins Andrade, Marcilio Cunha-Filho, Guilherne M Gelfuso, Tais Gratieri

引用次数: 0

Lipid cubosome nanoparticles for drug delivery. 用于药物递送的脂质立方体纳米颗粒。

IF 3.9

Nanomedicine (London, England) Pub Date : 2025-10-01 DOI: 10.1080/17435889.2025.2567841

Hayley C Parkin, Pawel Swietach, Helen Townley

引用次数: 0

Mechanism and applications of magnetoelectric nanoparticles in cancer therapy. 磁电纳米粒子在癌症治疗中的作用机制及应用。

IF 3.9

Nanomedicine (London, England) Pub Date : 2025-10-01 Epub Date: 2025-08-11 DOI: 10.1080/17435889.2025.2545746

Max Shotbolt, John Bryant, Ping Liang, Sakhrat Khizroev

{"title":"Mechanism and applications of magnetoelectric nanoparticles in cancer therapy.","authors":"Max Shotbolt, John Bryant, Ping Liang, Sakhrat Khizroev","doi":"10.1080/17435889.2025.2545746","DOIUrl":"10.1080/17435889.2025.2545746","url":null,"abstract":"Cancer remains a major clinical challenge, with current therapies often hampered by off-target effects, drug resistance, and incomplete tumor eradication. There is a pressing need for more precise and effective treatment strategies. This review explores the mechanisms and applications of magnetoelectric nanoparticles (MENPs) in cancer therapy. MENPs, typically composed of magnetostrictive and piezoelectric materials in a core-shell structure, generate electric fields in response to magnetic fields, enabling targeted and noninvasive therapeutic actions. The literature search included recent advances in MENP synthesis, optimization of material composition and morphology, and preclinical studies demonstrating their ability to enhance drug delivery, disrupt tumor cell membranes, and induce tumor regression without systemic toxicity. Relevant studies were identified by searching electronic databases, including PubMed, Web of Science, Scopus, and Google Scholar. The search employed a combination of keywords and phrases such as \"magnetoelectric nanoparticles,\" \"MENPs,\" \"cancer therapy,\" \"nanomedicine,\" \"core-shell nanoparticles,\" \"magnetostrictive,\" \"piezoelectric,\" \"drug delivery,\" \"magnetic field,\" \"nano-electroporation,\" and \"reactive oxygen species..\" MENPs represent a promising option for precision oncology, offering remote control over therapeutic effects and the potential to overcome limitations of conventional treatments. Ongoing research should focus on optimizing MENP design for selectivity and efficacy, as well as advancing their clinical translation for cancer therapy.","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"2469-2481"},"PeriodicalIF":3.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Theranostic applications of Raman-active gold nanoparticles. 拉曼活性金纳米颗粒的治疗应用。

IF 3.9

Nanomedicine (London, England) Pub Date : 2025-10-01 Epub Date: 2025-06-26 DOI: 10.1080/17435889.2025.2523233

Sanda Boca

引用次数: 0

Localized treatment of glioblastoma: a review of clinical strategies and advances in drug delivery systems. 胶质母细胞瘤的局部治疗：药物输送系统的临床策略和进展综述。

IF 3.9

Nanomedicine (London, England) Pub Date : 2025-10-01 Epub Date: 2025-08-28 DOI: 10.1080/17435889.2025.2550239

Cristiano Pesce, Giulia Rodella, Agnese Fragassi, Mariangela Garofalo, Stefano Salmaso, Paolo Caliceti, Bernard Gallez, Alessio Malfanti

{"title":"Localized treatment of glioblastoma: a review of clinical strategies and advances in drug delivery systems.","authors":"Cristiano Pesce, Giulia Rodella, Agnese Fragassi, Mariangela Garofalo, Stefano Salmaso, Paolo Caliceti, Bernard Gallez, Alessio Malfanti","doi":"10.1080/17435889.2025.2550239","DOIUrl":"10.1080/17435889.2025.2550239","url":null,"abstract":"The prognosis for glioblastoma patients remains poor despite recent advances in neurosurgery, chemotherapy, and radiotherapy. One promising treatment strategy lies in the localized delivery of therapeutics through drug delivery systems designed to enhance existing clinical treatments by directly targeting the tumor site or surrounding area. This review explores the latest advancements in localized therapies for glioblastoma, highlighting recent preclinical and clinical studies and examining how we can integrate these approaches - including stereotactic techniques such as convection-enhanced delivery and therapies targeting the post-surgical resection cavity - with drug delivery systems. We describe the features that the drug delivery system should possess for the efficient transport of drugs for both inoperable and resectable glioblastoma local treatment. Finally, this review discusses future directions that may facilitate the clinical translation of localized treatment strategies for glioblastoma.","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"2571-2599"},"PeriodicalIF":3.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12505517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic opportunities for nanomedicine with hollow one-dimensional silicon nanotubes. 利用一维空心硅纳米管进行纳米医学治疗的机会。

IF 3.9

Nanomedicine (London, England) Pub Date : 2025-10-01 Epub Date: 2025-08-14 DOI: 10.1080/17435889.2025.2545747

Nguyen T Le, Jeffery L Coffer

引用次数: 0

Strategies to enhance the effects of nanotechnology-mediated photodynamic therapy. 提高纳米技术介导的光动力治疗效果的策略。

IF 3.9

Nanomedicine (London, England) Pub Date : 2025-10-01 Epub Date: 2025-08-28 DOI: 10.1080/17435889.2025.2550233

Yanhan Mo, Xu Liu, Jian You, Lihua Luo

{"title":"Strategies to enhance the effects of nanotechnology-mediated photodynamic therapy.","authors":"Yanhan Mo, Xu Liu, Jian You, Lihua Luo","doi":"10.1080/17435889.2025.2550233","DOIUrl":"10.1080/17435889.2025.2550233","url":null,"abstract":"Photodynamic therapy (PDT) is a noninvasive therapeutic approach, particularly effective in tumor treatment. PDT utilizes photosensitizers (PSs) to absorb light at specific wavelengths, converting photon energy into chemical energy and subsequently generating cytotoxic reactive oxygen species (ROS). These ROS trigger cell death through apoptosis, necrosis and autophagy-related pathways. Compared with conventional therapies, PDT exhibits significant advantages, including high selectivity, repeatability, enhanced safety, minimal side effects, low drug resistance, and compatibility with radiotherapy or chemotherapy. However, due to the limited tissue penetration depth of light, PDT demonstrates suboptimal efficacy in treating deep tumors. Additionally, limitations such as poor targeting of photosensitizers and unfavorable factors in the tumor microenvironment greatly restrict PDT's therapeutic efficacy and clinical applicability. To enhance PDT efficacy, various strategies have been explored, among which nanotechnology has emerged as a key research focus. This review summarizes multiple approaches to augmenting nanotechnology-mediated PDT, with emphasis on achieving targeted delivery of photosensitizers (tissue, cell, and organelle-level), improving the performance of photosensitizers and modulating the tumor microenvironment. These insights provide theoretical guidance and practical references for developing novel and efficient PDT nanoplatforms. We conducted the literature search in PubMed, Elsevier ScienceDirect, Web of Science, Wiley and Scopus (from 2004 to 2025).","PeriodicalId":74240,"journal":{"name":"Nanomedicine (London, England)","volume":" ","pages":"2433-2457"},"PeriodicalIF":3.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0