Allergo JournalPub Date : 2024-12-12DOI: 10.1007/s15007-024-6371-5
Valentina Faihs, Johannes Ring, Knut Brockow, Kirsten Beyer, Ernst Rietschel, Sabine Schnadt, Britta Stöcker, Regina Treudler, Margitta Worm, Ludger Klimek
{"title":"Entlassmanagement nach Anaphylaxie","authors":"Valentina Faihs, Johannes Ring, Knut Brockow, Kirsten Beyer, Ernst Rietschel, Sabine Schnadt, Britta Stöcker, Regina Treudler, Margitta Worm, Ludger Klimek","doi":"10.1007/s15007-024-6371-5","DOIUrl":"10.1007/s15007-024-6371-5","url":null,"abstract":"<p>Personen, die eine Anaphylaxie erlitten haben, leiden oft unter weitreichenden Folgen im alltäglichen Leben. Leider ist das Entlassmanagement nach erfolgreicher Akutbehandlung oft immer noch unzureichend. Um weitere Reaktionen in der Zukunft zu verhindern und die Lebensqualität der Patienten zu verbessern, sind eine Reihe von Punkten zu beachten, die bei der Entlassung aus der Akuttherapie angesprochen beziehungsweise befolgt werden sollen: Dazu gehören eine genaue Anamneseerhebung zur Identifikation verdächtiger möglicher Auslöser, die Dokumentation der Akuttherapie, die Empfehlung zur weiteren allergologischen Abklärung sowie die Verordnung eines Notfallsets zur Selbsthilfe inklusive Adrenalin-Autoinjektor - mit Aufklärung und Übung über die Handhabung inklusive schriftlichem Notfallplan. Daneben sind Empfehlungen zur Meidung stark verdächtiger Auslöser sowie Hinweise auf Patientenorganisationen hilfreich. Dieser Artikel soll einen aktuellen Überblick über das Entlassmanagement nach erfolgreicher akuter Behandlung einer Anaphylaxie geben. Merke: „Nach der Anaphylaxie heißt auch potenziell vor der nächsten Anaphylaxie.“</p><p><b>Zitierweise:</b> Faihs V, Ring J, Brockow K, Beyer K, Rietschel E, Schnadt S, Stöcker B, Treudler R, Worm M, Klimek L. Discharge management after anaphylaxis. Allergo J Int 2024;33:275-81</p><p><b>https://doi.org/10.1007/s40629-024-00306-8</b></p>","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"33 8","pages":"16 - 25"},"PeriodicalIF":1.1,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142810897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Allergo JournalPub Date : 2024-12-12DOI: 10.1007/s15007-024-6403-1
Norbert Karl Mülleneisen
{"title":"Leserbrief: Präparatewechsel bei der AIT","authors":"Norbert Karl Mülleneisen","doi":"10.1007/s15007-024-6403-1","DOIUrl":"10.1007/s15007-024-6403-1","url":null,"abstract":"","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"33 8","pages":"67 - 67"},"PeriodicalIF":1.1,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142810833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Allergo JournalPub Date : 2024-12-12DOI: 10.1007/s15007-024-6415-x
Robert Bublak
{"title":"Neue Adjuvanzien für die AIT in Sicht","authors":"Robert Bublak","doi":"10.1007/s15007-024-6415-x","DOIUrl":"10.1007/s15007-024-6415-x","url":null,"abstract":"","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"33 8","pages":"15 - 15"},"PeriodicalIF":1.1,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142810899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Allergo JournalPub Date : 2024-12-12DOI: 10.1007/s15007-024-6395-x
Karin Weisser
{"title":"Toxicokinetics of aluminium - novel insights in an old adjuvant","authors":"Karin Weisser","doi":"10.1007/s15007-024-6395-x","DOIUrl":"10.1007/s15007-024-6395-x","url":null,"abstract":"<div><p><b>Purpose:</b> In 2015, an interdisciplinary project was started to fill the gap of knowledge on the toxicokinetics of aluminium (Al) after exposure from adjuvanted products for subcutaneous immunotherapy (SCIT).</p><p><b>Methods:</b> Two complementary initiatives of the project are explained. The results of two studies are reviewed and put in connection with the overarching goal. An estimate is given which steps have been reached and which are still needed.</p><p><b>Results:</b> Recent in vivo data provided evidence of systemically available Al from SCIT products in rats (Weisser et al. 2020 [1]). The data are highly valuable for further development of the physiology-based toxicokinetic (PBTK) model for Al exposure which has been established in parallel (Hethey et al. 2021 [2]).</p><p><b>Conclusion:</b> The Hethey model is an important step towards prediction of Al exposure in man from various sources. For use in risk assessment of Al exposure from SCIT products further extension of the model is warranted.</p><p><b>Cite this as:</b> Weisser K. Toxicokinetics of aluminium - novel insights in an old adjuvant. Allergo J Int 2024;33:304-8</p><p><b>https://doi.org/10.1007/s40629-024-00288-7</b></p></div>","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"33 8","pages":"48 - 53"},"PeriodicalIF":1.1,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142810972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}