Allergo Journal最新文献

{"title":"Chronische spontane Urtikaria schnell und langanhaltend therapieren","authors":"Martha-Luise Storre","doi":"10.1007/s15007-026-6755-9","DOIUrl":"10.1007/s15007-026-6755-9","url":null,"abstract":"","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"35 6","pages":"108 - 108"},"PeriodicalIF":0.4,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148950457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modulation of the microbiome by sublingual allergen immunotherapy: current insights and clinical implications","authors":"Peter Kunč,&nbsp;Jaroslav Fábry,&nbsp;Renata Péčová","doi":"10.1007/s15007-026-6747-9","DOIUrl":"10.1007/s15007-026-6747-9","url":null,"abstract":"<div><p><b>Background:</b> Specific allergen immunotherapy (AIT) represents the only causal treatment for allergic diseases capable of modifying the natural disease trajectory and inducing long-term allergen tolerance. Its sublingual form (SLIT) has emerged as a safe and highly effective alternative to conventional subcutaneous administration. In recent years, scientific interest has increasingly focused on the complex interplay between SLIT and the human microbiome.</p><p><b>Methods:</b> We conducted a targeted literature search across four major electronic databases (PubMed/MEDLINE, Scopus, Web of Science, and the Cochrane Library) from January 2012 to February 2026. Applying strict inclusion criteria, a narrative review approach underpinned by a systematic search strategy was utilized to qualitatively synthesize 41 peer-reviewed articles evaluating baseline dysbiosis, post-SLIT microbial shifts, and adjuvant interventions.</p><p><b>Results:</b> A growing body of evidence suggests that the therapeutic efficacy of SLIT is associated with alterations in microbial communities across the oral-gut-immune axis. However, recent clinical data present a more nuanced picture, indicating that clinical efficacy can occur without complete microbial normalization. Integrating these insights with established immunology highlights the microbiome's role as an epigenetic stabilizer in maintaining rather than merely initiating long-term allergen tolerance.</p><p><b>Conclusion:</b> Shifting toward precision allergology, we critically appraise the search for predictive baseline biomarkers, expose the severe methodological heterogeneity limiting current probiotic adjuvant trials, and underscore the unexplored potential of dietary interventions (e. g., fermentable fibers) to harness endogenous tolerogenic metabolites.</p><p><b>Cite this as</b> Kunč P, Fábry J, Péčová R. Modulation of the microbiome by sublingual allergen immunotherapy: current insights and clinical implications. Allergo J Int. 2026;35:194-202</p><p><b>https://doi.org/10.1007/s40629-026-00375-x</b></p></div>","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"35 6","pages":"54 - 63"},"PeriodicalIF":0.4,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148950454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Herzlich willkommen zum 21. DAK!","authors":"Ludger Klimek,&nbsp; Sven Becker","doi":"10.1007/s15007-026-6750-1","DOIUrl":"10.1007/s15007-026-6750-1","url":null,"abstract":"","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"35 6","pages":"64 - 64"},"PeriodicalIF":0.4,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148950461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kontakturtikaria durch Gamsfleisch","authors":"Malin Jachnow","doi":"10.1007/s15007-026-6745-y","DOIUrl":"10.1007/s15007-026-6745-y","url":null,"abstract":"","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"35 6","pages":"8 - 9"},"PeriodicalIF":0.4,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148950459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Datenschutz in der Allergologie – nötiger Schutz oder Hemmschuh?","authors":"Wolfram Hötzenecker,&nbsp; Ludger Klimek,&nbsp; Thilo Jakob","doi":"10.1007/s15007-026-6769-3","DOIUrl":"10.1007/s15007-026-6769-3","url":null,"abstract":"","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"35 6","pages":"3 - 3"},"PeriodicalIF":0.4,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148950438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Praxisnahe Fortbildung rund um die Allergologie","authors":"Nicola Zink","doi":"10.1007/s15007-026-6761-y","DOIUrl":"10.1007/s15007-026-6761-y","url":null,"abstract":"","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"35 6","pages":"112 - 112"},"PeriodicalIF":0.4,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148950451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Was bedeutet das „Spargesetz“ für die Arztpraxis?","authors":"Redaktion Facharztmagazine","doi":"10.1007/s15007-026-6768-4","DOIUrl":"10.1007/s15007-026-6768-4","url":null,"abstract":"","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"35 6","pages":"123 - 125"},"PeriodicalIF":0.4,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148950455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adrenalin-Nasenspray: neue Daten zum Anaphylaxie-Management","authors":"Redaktion Facharztmagazine","doi":"10.1007/s15007-026-6753-y","DOIUrl":"10.1007/s15007-026-6753-y","url":null,"abstract":"","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"35 6","pages":"108 - 108"},"PeriodicalIF":0.4,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148950462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neue Therapien für chronische spontane Urtikaria","authors":"Malin Jachnow","doi":"10.1007/s15007-026-6758-6","DOIUrl":"10.1007/s15007-026-6758-6","url":null,"abstract":"","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"35 6","pages":"114 - 115"},"PeriodicalIF":0.4,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148950465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Warum Hyposensibilisierungen abgelehnt werden","authors":"Malin Jachnow","doi":"10.1007/s15007-026-6743-0","DOIUrl":"10.1007/s15007-026-6743-0","url":null,"abstract":"","PeriodicalId":7418,"journal":{"name":"Allergo Journal","volume":"35 6","pages":"8 - 8"},"PeriodicalIF":0.4,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148950467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}