Med-X最新文献 - Book学术

Intelligent sensing devices and systems for personalized mental health. 用于个性化心理健康的智能传感设备和系统。

Med-X Pub Date : 2025-12-01 Epub Date: 2025-04-02 DOI: 10.1007/s44258-025-00057-3

Yantao Xing, Yang Yang, Kaiyuan Yang, Albert Lu, Luyi Xing, Ken Mackie, Feng Guo

{"title":"Intelligent sensing devices and systems for personalized mental health.","authors":"Yantao Xing, Yang Yang, Kaiyuan Yang, Albert Lu, Luyi Xing, Ken Mackie, Feng Guo","doi":"10.1007/s44258-025-00057-3","DOIUrl":"https://doi.org/10.1007/s44258-025-00057-3","url":null,"abstract":"Mental disorders disturb the cognition, emotion, and behavior of a diverse patient population, and can reduce their quality of life and even cause death. Despite significant advances in the diagnosis and treatment of mental disorders, challenges remain in achieving objective understanding, accurate assessment, and timely intervention for personalized conditions. Here, we review the recent development of intelligent sensing devices and systems for advancing the diagnosing, monitoring, and managing of mental disorders, with a special emphasis on personalized mental healthcare. We first introduce the mechanisms and clinical symptoms of mental disorders and related diagnostic principles. Then, we discuss the working principle and application of wearable sensors and systems to track various physiological parameters and markers for long-term monitoring, early screening, and treatment evaluation. Furthermore, we highlight recent emerging advancements in Artificial Intelligence (AI) and digital health and give perspectives on their integration with sensing technologies to address the emergent challenges of personalized mental healthcare. We believe innovative intelligent sensing technologies may significantly improve the patient's quality of life, enhance the efficiency and robustness of current healthcare systems, and reduce the socioeconomic burden for mental disorders and other diseases.","PeriodicalId":74169,"journal":{"name":"Med-X","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12363438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The continuous actuation of liquid metal with a 3D-printed electrowetting device. 用3d打印的电润湿装置连续驱动液态金属。

Med-X Pub Date : 2025-01-01 Epub Date: 2025-04-01 DOI: 10.1007/s44258-025-00052-8

Samannoy Ghosh, Rajan Neupane, Dwipak Prasad Sahu, Jian Teng, Yong Lin Kong

{"title":"The continuous actuation of liquid metal with a 3D-printed electrowetting device.","authors":"Samannoy Ghosh, Rajan Neupane, Dwipak Prasad Sahu, Jian Teng, Yong Lin Kong","doi":"10.1007/s44258-025-00052-8","DOIUrl":"10.1007/s44258-025-00052-8","url":null,"abstract":"The ability of liquid metals (LMs) to recover from repeated stretching and deformation is a particularly attractive attribute for soft bioelectronics. In addition to their high electrical and thermal conductivity, LMs can be actuated, potentially enabling highly durable electro-mechanical and microfluidics systems for applications such as cooling, drug delivery, or reconfigurable electronics. In particular, continuous electrowetting (CEW) phenomena can actuate liquid metal at relatively low voltage and affordable power requirements for wearable systems (~ < 10 V, ~ 10 - 100 µW) by inducing a surface tension gradient across the LM. However, sustaining LM actuation remains challenging due to factors such as electrolyte depletion, polarity changes in multi-electrode systems, and limitations related to LM composition. Here, we demonstrate LM actuation in a circular conduit for prolonged durations of at least nine hours. We enabled sustained actuation by sequentially applying short, direct current (DC) pulses through a multi-electrode system based on the dynamics of LM actuation. As a proof of concept, we also demonstrated the ability of LM to transport electrically conducting, non-conducting, and magnetic materials within a microchannel and show the liquid metal actuation system can be potentially miniaturized to the size of a wearable device. We envision that with further miniaturization of the device architectures, our CEW platform can enable future integration of low-voltage electro-mechanical systems into a broad range of wearable form factors.Graphical abstract: Supplementary information: The online version contains supplementary material available at 10.1007/s44258-025-00052-8.","PeriodicalId":74169,"journal":{"name":"Med-X","volume":"3 1","pages":"9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11958460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wireless, passive inductor-capacitor sensors for biomedical applications. 用于生物医学应用的无线无源电感电容器传感器。

Med-X Pub Date : 2025-01-01 Epub Date: 2025-08-21 DOI: 10.1007/s44258-025-00060-8

Baochun Xu, Shubham Patel, Cunjiang Yu

{"title":"Wireless, passive inductor-capacitor sensors for biomedical applications.","authors":"Baochun Xu, Shubham Patel, Cunjiang Yu","doi":"10.1007/s44258-025-00060-8","DOIUrl":"https://doi.org/10.1007/s44258-025-00060-8","url":null,"abstract":"In contemporary medical technologies, the necessity for efficient, precise, and real-time health monitoring and management is becoming increasingly critical with the prevalence of chronic diseases and the aging population. Traditional wired sensors and active wireless sensors continue to present numerous problems in practical applications, including complex structures, substantial size, frequent battery replacements, and an elevated risk of infection. Passive and wireless inductor-capacitor (LC) sensors are emerging as significant candidates to address these challenges. These sensors are typically constructed with a simple structure comprising a capacitor and an inductor, operating through magnetic coupling with external reading devices, thereby eliminating the necessity for batteries, connection wires, and peripheral circuits. This review commences with a succinct overview of the theoretical foundations, analyzing equivalent components and operational modes. It subsequently investigates sensor technologies by examining various types of sensors, including pressure, strain, humidity, temperature, and chemical sensors. Through the introduction of two primary scenarios-wearable and implantable-the review elucidates diverse advancements and requirements pertinent to biomedical applications. It concludes with a discussion of challenges and potential solutions to facilitate future developments in this field.Graphical abstract: ","PeriodicalId":74169,"journal":{"name":"Med-X","volume":"3 1","pages":"16"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perspectives on non-genetic optoelectronic modulation biointerfaces for advancing healthcare. 推进医疗保健的非遗传光电调制生物接口展望。

Med-X Pub Date : 2024-12-01 Epub Date: 2024-10-21 DOI: 10.1007/s44258-024-00030-6

Aman Majmudar, Saehyun Kim, Pengju Li, Bozhi Tian

{"title":"Perspectives on non-genetic optoelectronic modulation biointerfaces for advancing healthcare.","authors":"Aman Majmudar, Saehyun Kim, Pengju Li, Bozhi Tian","doi":"10.1007/s44258-024-00030-6","DOIUrl":"https://doi.org/10.1007/s44258-024-00030-6","url":null,"abstract":"Advancements in optoelectronic biointerfaces have revolutionized healthcare by enabling targeted stimulation and monitoring of cells, tissues, and organs. Photostimulation, a key application, offers precise control over biological processes, surpassing traditional modulation methods with increased spatial resolution and reduced invasiveness. This perspective highlights three approaches in non-genetic optoelectronic photostimulation: nanostructured phototransducers for cellular stimulation, micropatterned photoelectrode arrays for tissue stimulation, and thin-film flexible photoelectrodes for multiscale stimulation. Nanostructured phototransducers provide localized stimulation at the cellular or subcellular level, facilitating cellular therapy and regenerative medicine. Micropatterned photoelectrode arrays offer precise tissue stimulation, critical for targeted therapeutic interventions. Thin-film flexible photoelectrodes combine flexibility and biocompatibility for scalable medical applications. Beyond neuromodulation, optoelectronic biointerfaces hold promise in cardiology, oncology, wound healing, and endocrine and respiratory therapies. Future directions include integrating these devices with advanced imaging and feedback systems, developing wireless and biocompatible devices for long-term use, and creating multifunctional devices that combine photostimulation with other therapies. The integration of light and electronics through these biointerfaces paves the way for innovative, less invasive, and more accurate medical treatments, promising a transformative impact on patient care across various medical fields.","PeriodicalId":74169,"journal":{"name":"Med-X","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Strategic reuse of rapid antigen tests for coagulation status assessment: an integrated machine learning approach 凝血状态评估中快速抗原检测的战略性重复使用：一种综合机器学习方法

Med-X Pub Date : 2024-07-18 DOI: 10.1007/s44258-024-00025-3

Allan Sun, Arian Nasser, Chaohao Chen, Y. Zhao, Haimei Zhao, Zihao Wang, Wenlong Cheng, Pierre Qian, L. Ju

引用次数: 0

Atomic force microscopy in the characterization and clinical evaluation of neurological disorders: current and emerging technologies 原子力显微镜在神经系统疾病的表征和临床评估中的应用：现有技术和新兴技术

Med-X Pub Date : 2024-06-03 DOI: 10.1007/s44258-024-00022-6

David T. She, M. Nai, C. T. Lim

引用次数: 0

Biomaterials-enabled electrical stimulation for tissue healing and regeneration 利用生物材料电刺激促进组织愈合和再生

Med-X Pub Date : 2024-05-21 DOI: 10.1007/s44258-024-00020-8

Han-Sem Kim, Tanza Baby, Jung-Hwan Lee, U. Shin, Hae-Won Kim

引用次数: 0

Advancement in modulation of brain extracellular space and unlocking its potential for intervention of neurological diseases 调控脑细胞外空间并挖掘其干预神经系统疾病的潜力方面的进展

Med-X Pub Date : 2024-05-03 DOI: 10.1007/s44258-024-00021-7

Yu Yong, Yicong Cai, Jiawei Lin, Lin Ma, HongBin Han, Fenfang Li

引用次数: 0

Shear wave ultrasound elastography for estimating cartilage stiffness: implications for early detection of osteoarthritis 用于估算软骨硬度的剪切波超声弹性成像技术：对早期检测骨关节炎的意义

Med-X Pub Date : 2024-04-12 DOI: 10.1007/s44258-024-00018-2

Elias Georgas, Adnan Rayes, Junhang Zhang, Qifa Zhou, Yi-Xian Qin

引用次数: 0

Combining multi-mode thermal therapy with IL-6 and IL-17A neutralization amplifies antitumor immunity to facilitate long-term survival in LLC1-bearing mice 将多模式热疗法与 IL-6 和 IL-17A 中和疗法相结合，可增强抗肿瘤免疫力，促进 LLC1 携带小鼠的长期存活

Med-X Pub Date : 2024-04-03 DOI: 10.1007/s44258-024-00016-4

Jiamin Zheng, Jincheng Zou, Yue Lou, Shicheng Wang, Zelun Zhang, Junjun Wang, Peishan Du, Yongxin Zhu, Jiaqi You, Yichen Yao, Yuankai Hao, Aili Zhang, Ping Liu

引用次数: 0