发布求助
文献互助 智能选刊 最新文献

MedComm - Future medicine最新文献

筛选
英文 中文
Autophagy‐independent mitochondrial quality control: Mechanisms and disease associations 自噬-独立线粒体质量控制:机制和疾病关联
MedComm - Future medicine Pub Date : 2022-09-01 DOI: 10.1002/mef2.25
Feixiang Bao, Jiahui Xiao, Lingyan Zhou, Yanhua Xie, Yueqiao Li, Yi Wu, Xingguo Liu
{"title":"Autophagy‐independent mitochondrial quality control: Mechanisms and disease associations","authors":"Feixiang Bao, Jiahui Xiao, Lingyan Zhou, Yanhua Xie, Yueqiao Li, Yi Wu, Xingguo Liu","doi":"10.1002/mef2.25","DOIUrl":"https://doi.org/10.1002/mef2.25","url":null,"abstract":"","PeriodicalId":74135,"journal":{"name":"MedComm - Future medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41626944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Sodium Danshensu mediates human T lymphocyte activation via NF‐κB and MAPK pathway regulation 丹参素钠通过NF-κB和MAPK通路调节介导人T淋巴细胞活化
MedComm - Future medicine Pub Date : 2022-09-01 DOI: 10.1002/mef2.21
Yanan Chen, Rongrong Tian, Jin Xue, Jie Yu, Haibo Wang
{"title":"Sodium Danshensu mediates human T lymphocyte activation via NF‐κB and MAPK pathway regulation","authors":"Yanan Chen, Rongrong Tian, Jin Xue, Jie Yu, Haibo Wang","doi":"10.1002/mef2.21","DOIUrl":"https://doi.org/10.1002/mef2.21","url":null,"abstract":"","PeriodicalId":74135,"journal":{"name":"MedComm - Future medicine","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41286263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vivo gene therapy with CRISPR–Cas9: A promising therapeutic strategy to cure inherited diseases CRISPR–Cas9体内基因治疗：一种治疗遗传性疾病的有前景的策略
MedComm - Future medicine Pub Date : 2022-09-01 DOI: 10.1002/mef2.26
Fei Li, Taorui Wang, Qiang Cheng
{"title":"In vivo gene therapy with CRISPR–Cas9: A promising therapeutic strategy to cure inherited diseases","authors":"Fei Li, Taorui Wang, Qiang Cheng","doi":"10.1002/mef2.26","DOIUrl":"https://doi.org/10.1002/mef2.26","url":null,"abstract":"","PeriodicalId":74135,"journal":{"name":"MedComm - Future medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45953606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation of deep learning in drug design 深度学习在药物设计中的应用
MedComm - Future medicine Pub Date : 2022-09-01 DOI: 10.1002/mef2.18
Bo Yang, Kan Li, Xiuqin Zhong, Jun Zou
{"title":"Implementation of deep learning in drug design","authors":"Bo Yang, Kan Li, Xiuqin Zhong, Jun Zou","doi":"10.1002/mef2.18","DOIUrl":"https://doi.org/10.1002/mef2.18","url":null,"abstract":"","PeriodicalId":74135,"journal":{"name":"MedComm - Future medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41479025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A novel computational framework for integrating multidimensional data to enhance accuracy in predicting the prognosis of colorectal cancer 一种整合多维数据的新型计算框架，以提高预测结直肠癌预后的准确性
MedComm - Future medicine Pub Date : 2022-09-01 DOI: 10.1002/mef2.27
Qinran Zhang, Yuhong Xu, Shiyang Kang, Junquan Chen, Zhihao Yao, Haitao Wang, Qi-Nian Wu, Qi Zhao, Qihua Zhang, Ruifeng Xu, Xiufen Zou, Hui‐yan Luo
{"title":"A novel computational framework for integrating multidimensional data to enhance accuracy in predicting the prognosis of colorectal cancer","authors":"Qinran Zhang, Yuhong Xu, Shiyang Kang, Junquan Chen, Zhihao Yao, Haitao Wang, Qi-Nian Wu, Qi Zhao, Qihua Zhang, Ruifeng Xu, Xiufen Zou, Hui‐yan Luo","doi":"10.1002/mef2.27","DOIUrl":"https://doi.org/10.1002/mef2.27","url":null,"abstract":"","PeriodicalId":74135,"journal":{"name":"MedComm - Future medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41498721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changing clinical features of the 2022 monkeypox global health emergency 2022年猴痘全球突发卫生事件的临床特征变化
MedComm - Future medicine Pub Date : 2022-09-01 DOI: 10.1002/mef2.24
D. Baptista‐Hon, Gabriel João W. Fesalbon, Olivia Monteiro
{"title":"Changing clinical features of the 2022 monkeypox global health emergency","authors":"D. Baptista‐Hon, Gabriel João W. Fesalbon, Olivia Monteiro","doi":"10.1002/mef2.24","DOIUrl":"https://doi.org/10.1002/mef2.24","url":null,"abstract":"","PeriodicalId":74135,"journal":{"name":"MedComm - Future medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45205627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
SARS-CoV-2 modulation of RIG-I-MAVS signaling: Potential mechanisms of impairment on host antiviral immunity and therapeutic approaches. SARS-CoV-2调节RIG-I-MAVS信号:损害宿主抗病毒免疫的潜在机制和治疗方法
MedComm - Future medicine Pub Date : 2022-09-01 Epub Date: 2022-12-11 DOI: 10.1002/mef2.29
Mingming Wang, Yue Zhao, Juan Liu, Ting Li
{"title":"SARS-CoV-2 modulation of RIG-I-MAVS signaling: Potential mechanisms of impairment on host antiviral immunity and therapeutic approaches.","authors":"Mingming Wang,&nbsp;Yue Zhao,&nbsp;Juan Liu,&nbsp;Ting Li","doi":"10.1002/mef2.29","DOIUrl":"10.1002/mef2.29","url":null,"abstract":"<p><p>The coronavirus disease 2019 (COVID-19) is a global infectious disease aroused by RNA virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients may suffer from severe respiratory failure or even die, posing a huge challenge to global public health. Retinoic acid-inducible gene I (RIG-I) is one of the major pattern recognition receptors, function to recognize RNA viruses and mediate the innate immune response. RIG-1 and melanoma differentiation-associated gene 5 contain an N-terminal caspase recruitment domain that is activated upon detection of viral RNA in the cytoplasm of virus-infected cells. Activated RIG-I and mitochondrial antiviral signaling (MAVS) protein trigger a series of corresponding immune responses such as the production of type I interferon against viral infection. In this review, we are summarizing the role of the structural, nonstructural, and accessory proteins from SARS-CoV-2 on the RIG-I-MAVS pathway, and exploring the potential mechanism how SARS-CoV-2 could evade the host antiviral response. We then proposed that modulation of the RIG-I-MAVS signaling pathway might be a novel and effective therapeutic strategy to against COVID-19 as well as the constantly mutating coronavirus.</p>","PeriodicalId":74135,"journal":{"name":"MedComm - Future medicine","volume":"1 2","pages":"e29"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9913151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Dysbiosis of gut microbiome contributes to glaucoma pathogenesis 肠道菌群失调与青光眼发病有关
MedComm - Future medicine Pub Date : 2022-09-01 DOI: 10.1002/mef2.28
Shida Chen, Yayi Wang, Yaoming Liu, Fei Li, Yang Chen, Xiuli Fang, Tao Wen, Shuyi Xu, Daniel S. Kermany, Shufang Deng, Gen Li, Kang Zhang, Xiulan Zhang
{"title":"Dysbiosis of gut microbiome contributes to glaucoma pathogenesis","authors":"Shida Chen, Yayi Wang, Yaoming Liu, Fei Li, Yang Chen, Xiuli Fang, Tao Wen, Shuyi Xu, Daniel S. Kermany, Shufang Deng, Gen Li, Kang Zhang, Xiulan Zhang","doi":"10.1002/mef2.28","DOIUrl":"https://doi.org/10.1002/mef2.28","url":null,"abstract":"","PeriodicalId":74135,"journal":{"name":"MedComm - Future medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48550850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
How will previous infection or current vaccination strategies protect us from future SARS-CoV-2 variant infections? 以前的感染或当前的疫苗接种策略将如何保护我们免受未来的 SARS-CoV-2 变体感染？
MedComm - Future medicine Pub Date : 2022-09-01 Epub Date: 2022-10-17 DOI: 10.1002/mef2.20
Olivia Monteiro
{"title":"How will previous infection or current vaccination strategies protect us from future SARS-CoV-2 variant infections?","authors":"Olivia Monteiro","doi":"10.1002/mef2.20","DOIUrl":"10.1002/mef2.20","url":null,"abstract":"","PeriodicalId":74135,"journal":{"name":"MedComm - Future medicine","volume":"1 2","pages":"e20"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9911008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exosome‐based cancer stem cell communication: Implication for detecting and eliminating cancer stem cells 基于外泌体的癌症干细胞通讯:检测和消除癌症干细胞的意义
MedComm - Future medicine Pub Date : 2022-09-01 DOI: 10.1002/mef2.23
Abhishek Dutta, Swastika Paul
{"title":"Exosome‐based cancer stem cell communication: Implication for detecting and eliminating cancer stem cells","authors":"Abhishek Dutta, Swastika Paul","doi":"10.1002/mef2.23","DOIUrl":"https://doi.org/10.1002/mef2.23","url":null,"abstract":"","PeriodicalId":74135,"journal":{"name":"MedComm - Future medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44210872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信