Journal of dentistry (Shiraz, Iran)最新文献

{"title":"Comparison of Two Types of Composite-Opaquer Combinations Masking Ability for Tooth Discoloration without Clinically Visible Opacity.","authors":"Hossein Chalakinia, Farideh Darabi, Yasaman Sadeghi, Reza Tayefe Davalloo, Maryam Tavangar, Aidin Sooratgar","doi":"10.30476/dentjods.2024.100117.2192","DOIUrl":"10.30476/dentjods.2024.100117.2192","url":null,"abstract":"<p><strong>Background: </strong>A few studies have examined the masking ability of the combined application of opaquer and resin composites on tooth discoloration.</p><p><strong>Purpose: </strong>This study investigated the combined application of opaquer-composite to mask discolored backgrounds by utilizing two opaquers and resin composites.</p><p><strong>Materials and method: </strong>In this <i>in vitro</i> research, we used two composite resins, Vitalescence (Ultradent) and Gradia Direct (GC), and two opaquers: Pink opaque (Cosmedent) and Creative Color A2 (Cosmedent). Seventy-two specimens were made as disks in 8 groups (n=9), with 1.0mm and 0.5mm thicknesses. One surface of each disk was coated by one of the opaquers and cured. The 4mm-thick composite disks from both composite brands were also made as a reference, representing the inherent color of the material. Then, the composite disks from the opaquer-coated surface were placed on a C4 porcelain disk as a background to simulate a discolored tooth. Color measurement for all specimens was performed using a spectrophotometer device. The color difference of each test group and 4 mm thick disks of the same composite were measured using the formula CIELAB (ΔE * ab). Statistical analysis was performed by using ANOVA and Tukey's Post hoc tests.</p><p><strong>Results: </strong>Statistically significant differences were observed between the eight groups (<i>p</i>= 0.001). The thickness, composites, and opaquer variants significantly affected the ΔE*. The samples with 1mm thickness, the Vitalescence composite, and the Creative Color opaquer A2, had significantly lower ΔE* than the 0.5mm samples, the Gradia composite, and the Pink opaquer, respectively. The number of samples with desirable ΔE was significantly higher in the Vitalescence composite group than in the Gradia composite, and the Creative Color A2 opaquer had significantly more desirable ΔE than the Pink opaquer.</p><p><strong>Conclusion: </strong>Most results that achieved acceptable masking ability were obtained with combinations of Creative Color opaquer A2+ Vitalescence / Gradia composite in 0.5 or 1mm thicknesses.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 2","pages":"138-144"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating BMI, Upper Airway Dimensions, and Hyoid Bone Position and their Correlation in Non-OSA Snoring Adults: the First CBCT Study.","authors":"Sogol Jafari-Pozve, Nasim Jafari-Pozve, Ali Farzamfar, S Marjan Arianezhad, Seyed Sasan Aryanezhad","doi":"10.30476/dentjods.2024.102409.2360","DOIUrl":"10.30476/dentjods.2024.102409.2360","url":null,"abstract":"<p><strong>Background: </strong>Precise knowledge about the characteristics of individuals who snore but do not have obstructive sleep apnea (OSA) is essential yet remains limited in the literature.</p><p><strong>Purpose: </strong>This study aimed to evaluate BMI (body mass index), upper airway dimensions, hyoid bone position, and their relationship in non-OSA snoring adults using cone-beam computed tomography.</p><p><strong>Materials and method: </strong>In this retrospective cross-sectional study, cone beam computed tomography (CBCT) records of 100 patients were analyzed. Patients were snoring non-OSA individuals, diagnosed through a thorough examination and negative polysomnography results. CBCT scans were executed in the standard position as per the specified protocol of the Sleep Center. Upper airway was divided into four parts (nasopharynx, velopharynx, oropharynx, and hypopharynx), and anteroposterior (AP) and transverse (T) dimensions within the minimal cross-sectional area of each respective region were evaluated. BMI, upper airway dimension, and hyoid bone were analyzed using Pearson and Spearman's correlation tests.</p><p><strong>Results: </strong> The retrognathion-hyoid-4th cervical vertebra (RHV) angle representative of the hyoid position was significantly greater in females (<i>p</i> Value=0.000). It also statistically decreased significantly in snorers aged 36-50 and 51-65, <i>p</i>= 0.006 and 0.012, respectively. Snorers had above-average BMI in all age groups and both genders. The AP-hypopharynx significantly correlated with BMI (<i>p</i>= 0.022).</p><p><strong>Conclusion: </strong> The hyoid position was gender-dependent, with a superior position in females. It was also age-dependent, with a more inferior position in snorers aged 36-65 compared to younger ages (20-35). The AP-velopharynx is a constriction region in the airway of snorers. Snorers were overweight in all age groups and both genders. BMI had a significant correlation with the AP-hypopharynx.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 2","pages":"160-170"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micro-Computed Tomography Assessment of the Quality of Obturation (Voids) of Single-Canal Maxillary Second Premolars by the Lateral Compaction versus Continuous Warm Vertical Condensation Techniques.","authors":"Romina Hajipour, Maryam Zare Jahromi, Masood Khabiri","doi":"10.30476/dentjods.2024.99581.2159","DOIUrl":"https://doi.org/10.30476/dentjods.2024.99581.2159","url":null,"abstract":"<p><strong>Statement of the problem: </strong>One of the most important stages of root canal treatment is obturation for the root canal, an obturation with less voids will have fewer treatment complications in the future.</p><p><strong>Purpose: </strong>This study was conducted to compare the quality of obturation of single-canal maxillary second premolars by the cold lateral compaction (CLC) versus continuous warm vertical condensation (CWVC) techniques using micro-CT.</p><p><strong>Materials and method: </strong>In this experimental study, 36 extracted single-canal maxillary premolars were selected. The root canals were instrumented by Denco Blue rotary files. The teeth were randomly assigned to three groups (n=12) of control (no root filling), root canal obturation with CLC technique, and root canal obturation with CWVC technique. Next, they underwent micro-CT, and the mean volume and volume percentage (VP) of voids were calculated in the apical, middle, and coronal thirds of the root canals. Data were analyzed using one-way ANOVA, the Kruskal-Wallis, Mann-Whitney U, Bonferroni, Dunnett, Tukey, and independent t-tests (<i>p</i> Value<0.05).</p><p><strong>Results: </strong>In the coronal third, no significant difference was found between the CLC and CWVC groups in the mean volume of voids (<i>p</i>= 0.273), the mean volume of filled space (<i>p</i>= 0.419), or the VP of voids (<i>p</i>= 0.605). The highest mean volume and VP of voids were recorded in the coronal part of the group CWVC (<i>p</i>> 0.05). The lowest mean volume and VP of voids was recorded in the apical third in CWVC group (<i>p</i>< 0.05).</p><p><strong>Conclusion: </strong>None of the obturation techniques could provide a void-free root filling. Two techniques showed no significant difference regarding the mean volume and VP of voids in obturation of single-canal maxillary second premolars.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"48-54"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dentin Sialophosphoprotein Expression Profile in Developing Human Primary Teeth: An Experimental Study.","authors":"Soussan Irani, Shohreh Alimohammadi, Fatemeh Ataei","doi":"10.30476/dentjods.2024.100219.2202","DOIUrl":"https://doi.org/10.30476/dentjods.2024.100219.2202","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Tooth development is initiated by localized thickenings of the primary epithelial bands. Dentin sialophosphoprotein (DSPP) is the most abundant non-collagenous protein in the dentin matrix. DSPP's expression extends to multiple tissues, including dentin, cementum, and bone. However, the role of DSPP is not yet clear in the development of human tooth.</p><p><strong>Purpose: </strong>The current study aimed to examine the DSPP expression profile during the development of human primary tooth structures with a sufficiently large sample size.</p><p><strong>Materials and method: </strong>In this experimental study, a total of 33 samples of aborted human fetuses were divided into three age groups <16 weeks, <19 weeks and ≥19 weeks. Immunohistochemistry (IHC) was performed with Anti-DSPP rabbit polyclonal antibody. A two-way ANOVA analysis was conducted to examine the differences between the groups (<i>p</i>< 0.05).</p><p><strong>Results: </strong>An increase in DSPP expression was observed with the progression of gestational weeks in different histological structures of developing human primary teeth.</p><p><strong>Conclusion: </strong>An increase in the expression level of DSPP with the progression of gestational weeks may confirm that reciprocal interactions between the enamel organ (EO) and dental pulp cells contribute to tooth formation.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"55-60"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Authors' Reply.","authors":"Mohamad Reza Golzar Feshalami, Mehraban Shahi, Nasrin Davari Dolatabadi","doi":"10.30476/dentjods.2024.50388","DOIUrl":"https://doi.org/10.30476/dentjods.2024.50388","url":null,"abstract":"","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"100"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Odontogenic Tumors: A Challenge for Clinical Diagnosis and an Opportunity for AI Innovation\".","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.30476/dentjods.2024.103266.2437","DOIUrl":"https://doi.org/10.30476/dentjods.2024.103266.2437","url":null,"abstract":"","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"99"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Hand Files, Mtwo, Reciproc, and Gentlefile Rotary Systems Regarding Canal Transportation, Centering Ability, and Obturation Quality of Primary Molars.","authors":"Maryam Kakoienejad, Mobina Najafifard, Sara Tavassoli-Hojjati, Ladan Hafezi, Saba Aghaei","doi":"10.30476/dentjods.2024.100763.2247","DOIUrl":"10.30476/dentjods.2024.100763.2247","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Employing different instruments may have different impact on the outcome of root canal treatments. Deviation from the original canal path and defective root canal obturation may lead to pulpectomy treatment failure.</p><p><strong>Purpose: </strong>This study compared the primary molar canal transportation, centering ability, and obturation quality of hand files, Mtwo, Reciproc, and Gentlefile rotating machines in root canal treatments.</p><p><strong>Materials and method: </strong>In this <i>in vitro</i> experimental study, eighty primary molar roots were randomly assigned to four groups. Cone-beam computed tomography (CBCT) scans were provided for the samples, and hand files (group 1), Mtwo (group 2), Reciproc (group 3), and Gentlefile (group 4) were used to instrument the root canals. Once more, CBCT scans were acquired, and at 1, 2, and 3mm from the apex as well as 1 mm from the orifice, the canal transportation and centering ability were evaluated in buccolingual and mesiodistal directions. Zeolite (ZOE) cement was used to obturate every root canal. To evaluate the obturation density, number of voids, and underfilling in each group, new CBCT scans were obtained. For every tooth, the maximum, minimum, and average Hounsfield units (HU) were noted. One-way ANOVA, the Kruskal-Wallis test, and Tukey's HSD test were used to analyze the data.</p><p><strong>Results: </strong>Mtwo exhibited considerably superior centering ability than Gentlefile at 2mm from the apex in the mesiodistal direction (<i>p</i> Value< 0.05). Gentlefile had significantly higher buccolingual canal transportation than Reciproc at 3 mm from the apex (P0.05). Minimum HU, underfilling, and void numbers did not differ amongst the four groups (<i>p</i>= 0.791, <i>p</i>= 0.1, and <i>p</i>= 0.548). Reciproc had substantially higher maximum and average HU, followed by Mtwo, Gentlefile, and hand files (<i>p</i>< 0.05).</p><p><strong>Conclusion: </strong>When compared to other systems, Gentlefile showed higher transportation and less centering ability. Reciproc had the highest obturation density, followed by Mtwo, Gentlefile, and hand files.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"76-87"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Literature Review of Stainless Steel Crown for Permanent Molars: Indications, Survival, Periodontal and Radiographic Findings.","authors":"Pooya Vatankhah, Fatemeh Hashemi, Alireza Sarraf Shirazi","doi":"10.30476/dentjods.2024.101475.2301","DOIUrl":"https://doi.org/10.30476/dentjods.2024.101475.2301","url":null,"abstract":"<p><p>Stainless steel crowns (SSCs) are the preferred choice for restoring primary molars with extensive caries. However, they may be indicated for permanent molars in certain cases as well. While limited research assessed different aspects of this treatment separately, this review aims to consolidate the existing literature and provide a multi-dimensional analysis of preformed metal crown restoration for permanent molars. A comprehensive search of electronic databases including PubMed, Scopus, Web of Science, Embase, and Cochrane was conducted, and relevant studies were categorized based on specific aspects of this treatment including indications, survival rates, periodontal and radiographic findings, utilization frequency, and alternative options. The review highlights the wide range of indications for SSCs on permanent molars of children, adolescents, and even adults, along with their remarkable success rates. However, noticeable underutilization, despite their proven efficacy, was observed. Periodontal defects and marginal discrepancies were found to be the most common causes of failures.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"8-16"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Calcifying Odontogenic Cyst in Posterior Maxilla: A Case Report.","authors":"Farhad Ghorbani, Mohammad Amin Amiri, Mohammad Mehdi Farahmand, Saeed Afzoun, Maryam Paknahad","doi":"10.30476/dentjods.2024.102636.2375","DOIUrl":"https://doi.org/10.30476/dentjods.2024.102636.2375","url":null,"abstract":"<p><p>In the present study, we reported a 66-year-old woman with an uncommonly painful calcifying odontogenic cyst (COC) in the posterior region of the left side of the maxilla. The cyst was evaluated radiographically and histopathologically. The present case showed a multilocular cyst with a mixed internal structure. The most noticeable effects on the peripheral structures were elevated maxillary sinus floor, osteomeatal complex, and nasal obstruction. To better understand the impact of COC on the trabecular pattern of the surrounding bone, we performed fractal analysis on the panoramic images pre- and post-operatively. The expansion of COC can change the trabecular pattern, which subsequently can change the fractal dimension of the area. After histopathological confirmation of the diagnosis, the cyst was surgically removed.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"88-94"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between <i>JAK2</i>, <i>STAT3</i>, and <i>CTLA4</i> Relative Gene Expressions and Oral Squamous Cell Carcinoma.","authors":"Hamideh Kadeh, Tayebeh Baranzehi, Milad Mollaali, Neda Maserat, Mohammad Javad Shahraki, Dor Mohammad Kordi-Tamandani","doi":"10.30476/dentjods.2024.100237.2205","DOIUrl":"https://doi.org/10.30476/dentjods.2024.100237.2205","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Oral squamous cell carcinoma (OSCC) is the eighth leading cause of cancer-related death worldwide. <i>JAK2</i> and <i>STAT3</i> primarily influence intrinsic tumor cell behavior, and <i>CTLA4</i> impacts the interplay between the tumor and the host immune system in the context of cancers. There is scarce information regarding the involvement and roles of <i>JAK2</i>, <i>STAT3</i>, and <i>CTLA4</i> genes in OSCC; however, the molecular mechanisms are still unclear.</p><p><strong>Purpose: </strong>This study examined the relationship between <i>JAK2</i>, <i>STAT3</i>, and <i>CTLA4</i> gene expression levels and OSCC in a group of patients in the southeast of Iran.</p><p><strong>Materials and method: </strong>This cross-sectional study was conducted in which the relative gene expression levels of <i>JAK2</i>, <i>STAT3</i>, and <i>CTLA4</i> were compared between 23 oral paraffin tissue blocks collected from OSCC patients and 20 fresh gingival tissues collected from healthy individuals. The Real-Time quantitative PCR (RT-qPCR) assay was employed to assess relative gene expression levels. SPSS 27 was employed to perform statistical analyses.</p><p><strong>Results: </strong>Significant differences were found between OSCC patients and healthy individuals concerning gene expression levels of <i>JAK2</i> (2.4-fold, <i>p</i>< 0.0001), <i>STAT3</i> (2.32-fold, <i>p</i>< 0.0001), and <i>CTLA4</i> (4.09-fold, <i>p</i>< 0.0001). Additionally, there were significant positive correlations among <i>JAK2-STAT3</i> (ρ= 0.667, <i>p</i>< 0.001), <i>JAK2-CTLA4</i> (ρ= 0.771, <i>p</i>< 0.001), and <i>STAT3-CTLA4</i> (ρ= 0.635, <i>p</i>= 0.001) co-expressions. Moreover, gender, age groups, and tumor locations did not significantly correlate with the expression levels of these genes (<i>p</i>> 0.05). Nevertheless, significant differences occurred between histopathological grades and the gene expression levels of <i>JAK2</i> (<i>p</i>< 0.001), <i>STAT3</i> (<i>p</i>= 0.001), and <i>CTLA4</i> (<i>p</i>< 0.001).</p><p><strong>Conclusion: </strong>The overexpression of <i>JAK2</i>, <i>STAT3</i>, and <i>CTLA4</i> can be considered triggers for OSCC development. It may be beneficial to conduct future research on OSCC by considering downstream genes involved in the <i>JAK2</i>/<i>STAT3</i>/<i>CTLA4</i> axis.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 1","pages":"25-32"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}