Journal of dentistry (Shiraz, Iran)最新文献

{"title":"Evaluation of Antibacterial and Cytotoxic Potency of Polyherbal Gel Formulation Containing <i>Achyranthes Aspera</i> and <i>Trachyspermum Ammi</i> as Intracanal Medicament: An <i>in vitro</i> Study.","authors":"Ram Surath Kumar, Anil V Ankola, Mahantesh B Nagamoti, Roopali M Sankeshwari, Kishori P Sutar, Shushant I Jigan, Atrey J Pai Khot, Ritiha Uppin","doi":"10.30476/dentjods.2024.100380.2218","DOIUrl":"10.30476/dentjods.2024.100380.2218","url":null,"abstract":"<p><strong>Background: </strong>The overwhelming increase of antibiotic-resistant bacteria, and the adverse reactions of using synthetic drugs such as chlorhexidine (CHX) and calcium hydroxide (Ca(OH₂))- based intracanal medicaments have made it mandatory to search for effective substitutes. Herbal medicines like <i>Achyranthes Aspera</i> (<i>A.aspera</i>) and <i>Trachyspermum Ammi</i> (<i>T.ammi</i>) have been used in many clinical conditions and it appears to be a distinct material next to Ca(OH₂) in the field of dentistry.</p><p><strong>Purpose: </strong>Evaluate the antibacterial potential and cytotoxic effects of novel polyherbal gel containing <i>A.aspera</i> and <i>T.ammi</i>, CHX gel, and Ca(OH₂) paste based intracanal medicaments in root canal treatment against <i>Enterococcus faecalis</i> (<i>E.faecalis</i>).</p><p><strong>Materials and method: </strong>In this <i>in vitro</i> study, Ethanolic extracts of <i>A.aspera</i> and <i>T.ammi</i> were prepared by the Soxhlet apparatus method. The individual plant extracts and the plant extract mixtures (1:1, 2:1, and 1:2), CHX, and Ca(OH₂) were assessed for minimum inhibitory concentration (resazurin microtiter assay), fractional inhibitory concentration and minimum bactericidal concentration (spread plating method) against <i>E.faecalis</i>. The polyherbal intracanal medicament was assessed for zone of inhibition (well diffusion method) and cytotoxicity ( MTT assay) on human periodontal ligament cells. All experiments were performed in triplicate.</p><p><strong>Results: </strong>Polyherbal gel containing <i>A.aspera</i> and <i>T.ammi</i>, CHX gel, and Ca(OH₂) paste-based intracanal medicaments showed statistically significant antibacterial activity (<i>p</i> <0.05) against <i>E.faecalis</i> with CHX showing superior properties followed by polyherbal gel. The results of the cytotoxicity assay demonstrated the good biocompatibility of the polyherbal intracanal medication, which exhibited 95.13% of surviving cells.</p><p><strong>Conclusion: </strong>The use of herbal alternatives as an intracanal medicament proved to be advantageous considering the several undesirable characteristics of CHX and Ca(OH₂).</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 2","pages":"101-111"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infrequent Histopathologic Subtypes of Oral Squamous Cell Carcinoma: A Case Series with Emphasis on Histopathologic Characteristics.","authors":"Saede Atarbashi-Moghadam, Ali Lotfi, Leyla Roghanizadeh, Seyed Sepehr Mirebeigi Jamasbi, Zeinab Akbarzadeh Fathabadi","doi":"10.30476/dentjods.2025.103223.2435","DOIUrl":"10.30476/dentjods.2025.103223.2435","url":null,"abstract":"<p><p>Squamous cell carcinoma (SCC) is the most common oral malignancy. Conventional types are classified as well-, moderately- and poorly differentiated, which are usually easy to diagnose microscopically. Still, uncommon variants such as basaloid, verrucous, spindle cell, papillary, adenosquamous, acantholytic, cuniculatum, clear cell, and pigmented SCC make a diagnostic challenge for pathologists. This report presents four rare cases of oral SCC with histopathologic diagnosis of spindle cell carcinoma, carcinoma cuniculatum, papillary SCC, and basaloid SCC focusing on microscopic characteristics and differential diagnosis. The apprehensive knowledge about the unique histopathologic features of these uncommon variants is crucial to avoid their misdiagnoses and provide appropriate treatment.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 2","pages":"186-193"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Try-in Paste Shade and Framework Design on the Color Characteristics of Dental Zirconia Restorations.","authors":"Abolghasem Mohammadi, Alireza Gerami, Sara Tavakolizadeh, Rahab Ghoveizi, Ehsan Rouhollahpour Ahangar","doi":"10.30476/dentjods.2024.100644.2235","DOIUrl":"10.30476/dentjods.2024.100644.2235","url":null,"abstract":"<p><strong>Background: </strong>Favorable esthetic and mechanical qualities, together with rapid advancements in CAD/CAM technology, have increased the adoption of zirconia restorations. Despite acceptable optical characteristics of zirconia, achieving natural tooth color resemblance remains challenging.</p><p><strong>Purpose: </strong>This study was conducted to determine how the try-in paste shade, tooth region, and framework design affect the color properties of zirconia restorations.</p><p><strong>Materials and method: </strong>In this in vitro study, a maxillary central incisor was prepared and scanned. Frameworks with four different designs were fabricated. Ten crowns were designed in each group categorized as simple core (SC), dentin core (DC), trestle design core (TC), and monolithic crown (MC). Veneering was performed for all groups except MC. Subsequently, all crowns were cemented with try-in paste Bisco CHOICE 2 cement in shades A1-A3 and B1. The color data (Lab) were determined using the SpectroShade Micro II device. Color difference (ΔE) with the Lab B2 color sample as the target color was calculated using the CIE ΔE 2000 formula. Data analysis was performed using the repeated measure ANOVA test.</p><p><strong>Results: </strong>Zirconia core design, tooth region and cement shade, significantly impacted the ΔE and there were interactions among these factors. The highest ΔE was observed when no cement was used, while the lowest ΔE was observed with A2 cement. Among the various framework designs, the lowest and highest ΔEs were observed in MC and, SC frames, respectively (<i>p</i> Value < 0.05).</p><p><strong>Conclusion: </strong>In the light of the findings of current study, minimum ΔE can be achieved with trestle design framework at the middle portion of the tooth. The try-in paste shade also has a considerable impact on the final ΔE value.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 2","pages":"151-159"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Remineralizing Agents for Prevention of Microhardness Reduction and Change in Mineral Content of Enamel in Anterior Primary Teeth after Exposure to Iron Drop.","authors":"Aneseh Sadat Tabatabaei Rad, Sara Tavassoli-Hojjati, Reyhane Sadat Hoda, Saba Aghaei","doi":"10.30476/dentjods.2024.100763.2247","DOIUrl":"10.30476/dentjods.2024.100763.2247","url":null,"abstract":"<p><strong>Background: </strong>Some alterations in the enamel structure of primary teeth have been reported following iron drop consumption. The efficacy of different remineralizing agents for this problem is still challenging.</p><p><strong>Purpose: </strong>This study aimed to assess the efficacy of remineralizing agents for prevention of microhardness reduction and change in primary enamel mineral content after exposure to iron drop.</p><p><strong>Materials and method: </strong>In this experimental study, 36 sound primary anterior teeth were assigned to four groups of control, casein phosphopeptide amorphous calcium phosphate (CPP-ACP), fluoride varnish (FV), and CPP-ACP+FV (MI varnish). The baseline microhardness of the teeth was first measured by Vickers hardness tester using 50 g load for 10 seconds. Next, the microhardness was measured after remineralizing agents were applied on the specimens. After the application of iron drop for 5 minutes, and pH cycling for 10 days, the final microhardness of specimens was registered. Specimens were also subjected to energy dispersive X-ray spectroscopy (EDS) in the control group, after remineralization and after the application of iron drop. Data were analyzed by one-way ANOVA, Tukey's test, and Tamhane's test.</p><p><strong>Results: </strong>The final microhardness was significantly higher in all remineralized groups compared to the control group (<i>p</i> Value= 0.003). The final microhardness was significantly higher in MI varnish compared to FV (<i>p</i>= 0.027), CPP-ACP (<i>p</i>= 0.03), and control (<i>p</i>< 0.0001) groups. According to EDS, calcium (Ca) and ferric (Fe) content were significantly different between the remineralizing groups and control groups in the final step (<i>p</i>< 0.00001).</p><p><strong>Conclusion: </strong>Application of CPP-ACP, FV, and MI varnish prior to iron drop exposure can improve microhardness. MI varnish had significantly higher efficacy for this purpose than the other two remineralizing agents.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 2","pages":"112-120"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12211987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Quality of Providing Dental Services in the School of Dentistry and Private Clinics in Shiraz, Based on the SERVQUAL Model.","authors":"Maryam Bakhtiar, Mohsen Sharif Zadeh Ardakani, Mohammad Reza Mokarram, Samaneh Ansarifar, Mehrdad Vossoughi","doi":"10.30476/dentjods.2024.99413.2149","DOIUrl":"10.30476/dentjods.2024.99413.2149","url":null,"abstract":"<p><strong>Background: </strong>The quality of dental services is an important factor in patient satisfaction and health outcomes. However, there is a lack of studies, which compare the quality of dental services provided in different settings such as dental schools and private clinics and measure the gap between patients' expectations and perceptions.</p><p><strong>Purpose: </strong>This study aims to assess and compare the quality of dental services in Shiraz Dental School and private clinics using the SERVQUAL model and identify the dimensions that affect patient satisfaction.</p><p><strong>Materials and method: </strong>In this cross-sectional descriptive study, 440 patients of the Shiraz dental school and private clinics in Shiraz participated in answering the SERVQUAL questionnaire to measure the perceptions and expectations of patients in six dimensions (tangibility, reliability, responsiveness, assurance, empathy, and access).</p><p><strong>Results: </strong>The mean gap score was (-1.27±0.59) for private clinics and (-0.40±0.45) for dental school, which was significant (<i>p</i>< 0.001) between expectations and perceptions in all dimensions in both settings. In private clinics, the largest gap was in the empathy dimension (-1.64±0.65) and the smallest gap was in the assurance dimension (-1.05±0.64). In the Shiraz dental school, the largest gap was in the tangibility dimension (-0.72±0.60) and the smallest gap was in the assurance dimension (-0.59±0.65).</p><p><strong>Conclusion: </strong>The patients were satisfied with the services provided in the Shiraz dental school and private clinics of Shiraz, but the expectations of the patients were not met in all dimensions, which require periodic evaluations along with policies to respond to the needs and expectations of the patients in providing services in both sectors.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 2","pages":"121-130"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the Inhibitory Effect of Kefir Drink and Chlorhexidine Mouthwash against Oral Bacteria in Orthodontic Patients.","authors":"Leila Jabbareh, Hodis Ehsani, Hamidreza Goli, Abolfazl Hosseinnataj, Sajjad Ebadian, Melika Mollaei, Tahura Etezadi","doi":"10.30476/dentjods.2024.102609.2371","DOIUrl":"10.30476/dentjods.2024.102609.2371","url":null,"abstract":"<p><strong>Background: </strong>The presence of orthodontic appliances in the oral cavity increases the number of cariogenic microorganisms, highlighting the risk of periodontal disease and dental caries. Many approaches can be employed to overcome this problem.</p><p><strong>Purpose: </strong>This study was conducted to compare the effect of kefir drink with chlorhexidine (CHX) mouthwash on the growth of oral bacteria in patients undergoing orthodontic treatment.</p><p><strong>Materials and method: </strong>In this single-blind clinical trial study, 30 candidates for orthodontic treatment were selected and randomly divided into two groups (N=15). The intervention group received 100 ml of Kefir drink twice daily, while the control group used 10 ml of 0.2% mouthwash for 20 days. Microbial sampling was done three times including before intervention, immediately after intervention, and 20 days after intervention. Data were analyzed using SPSS software V.23 with a significance level of less than 0.05.</p><p><strong>Results: </strong>The findings suggested that the number of bacteria in the CHX group was significantly higher than in the intervention group (<i>p</i>= 0.003). However, no significant difference was observed between the two groups after 20 days (<i>p</i>= 0.148). Furthermore, the number of bacteria decreased significantly in both groups over time.</p><p><strong>Conclusion: </strong>Both CHX and Kefir have antibacterial properties against oral bacteria.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 2","pages":"171-176"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12205136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunohistochemical Analysis of Oral Spindle Cell Hemangioma.","authors":"Amit Mani, Manas Bajpai, Saurabh L Sabnis","doi":"10.30476/dentjods.2024.101499.2305","DOIUrl":"10.30476/dentjods.2024.101499.2305","url":null,"abstract":"<p><p>Spindle cell hemangioma (SCH), formerly called \"spindle cell hemangioendothelioma\", is a rare benign histological variant of hemangioma characterized by the presence of two contrast zones, the first zone exhibits large dilated cavernous space with slit-like vascular spaces may show clear endothelial vacuoles resembling fat cells. SCH is often considered as pseudosarcomatous entity; it imposes a diagnostic challenge for oral pathologists due to its resemblance with Kaposi sarcoma. A total of 13 cases of SCH have been reported in the head and neck region to date and only 6 cases have been reported inside the oral cavity. We present a rare case of SCH located on the hard palate, which imitated Kaposi's sarcoma on histopathological examination. The expressions of various markers including EGR, CD 31, and HHV 8 yielded the final diagnosis of SCH. The markers EGR and HHV 8 have never been used in intraoral SCH before to the best of our knowledge; hence, the present report highlights the use of immunohistochemistry for the diagnosis of SCH.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 2","pages":"194-198"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunohistochemical Expression of Baculoviral Inhibitor of Apoptotic Proteins Repeat-Containing Protein in Tumors of Salivary Gland Origin.","authors":"Shima Torabi Ardekani, Hosein Mirhadi, Seyed Ali Ghaboos, Raziyeh Zare, Marzieh Khajeh","doi":"10.30476/dentjods.2024.99323.2139","DOIUrl":"10.30476/dentjods.2024.99323.2139","url":null,"abstract":"<p><strong>Background: </strong>Salivary gland tumors (SGTs) include benign and malignant tumors, such as pleomorphic adenoma (PA), mucoepidermoid carcinoma (MEC), and adenoid cystic carcinoma (ACC). Baculoviral inhibitors of apoptotic proteins (BIAPs) repeat-containing protein 6 (BIRC6), is an anti-apoptotic protein that plays an important role in cancers.</p><p><strong>Purpose: </strong>We aimed to evaluate the expression of BIRC6 in SGTs and its correlation with the clinicopathological features.</p><p><strong>Materials and method: </strong>In this cross-sectional study, 56 SGT tissue samples, including 15 cases of MEC, 20 cases of ACC, and 21 cases of PA, as well as nine cases of normal salivary gland tissues, were investigated for BIRC6 expression by immunohistochemical analysis.</p><p><strong>Results: </strong>BIRC6 was found in 2.50%, 63%, 88%, and 63% of normal tissue, MEC, ACC, and PA, respectively. The mean total score of BIRC6 expression was 9.13; for ACC, MEC, PA, and normal tissue of the salivary gland were 10.25, 9.13, 9.00, and 3.00, respectively. The high expression of BIRC6 was detected in 29 cases of malignant and 15 cases of benign SGTs. The frequency of high or low expression was not different between the male and female patients (<i>p</i>= 0.833), patients aged below or above 65 years (<i>p</i>= 0.950), patients with different tumor sizes (<i>p</i>= 0.734), and metastasis status (<i>p</i>= 0.977).</p><p><strong>Conclusion: </strong>The higher expression intensity and percentage of BIRC6 in malignant and benign SGTs suggests it as a potential marker to be used in future targeted therapy for SGTs.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 2","pages":"131-137"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Lubricant on the Detorque Force of Locator/Kerator Abutment in Overdenture Patients: A Pilot Clinical Study.","authors":"Ali Chamani, Davood Aghasizadeh, Hamidreza Rajati Haghi, Ghazal Aghebati, Reza Shakiba","doi":"10.30476/dentjods.2024.101754.2316","DOIUrl":"10.30476/dentjods.2024.101754.2316","url":null,"abstract":"<p><strong>Background: </strong>Despite the implants' remarkable success, mechanical failure of implant-abutment screws is a challenge for clinicians. Among the types of mechanical failures, abutment screw loosening is still frequently reported in the literature.</p><p><strong>Purpose: </strong>The present study aimed to evaluate the effect of using lubricant on the detorque force (removal force) of locator/kerator abutment in overdenture patients after 6 months of clinical usage.</p><p><strong>Materials and method: </strong>This pilot clinical study examined the detorque force of implants in 20 edentulous patients with two mandibular implants positioned between the mental foramen. The patients underwent the fabrication of a complete maxillary prosthesis and mandibular overdenture. Before loading attachments in the delivery session, healing abutments were removed, and implant interiors dried, randomly some fixtures received a tetracycline eye ointment 1% lubricant, while the others remained non-lubricated. Abutments were secured with prescribed torque according to implant system guidelines (20 N.cm). After 6 months, detorque forces for the abutment locators were measured using a torque meter. Descriptive statistics, mean comparison, and Pearson correlation were performed on the obtained data. A significant level of <i>p</i> Value<0.05 was considered in the present study.</p><p><strong>Results: </strong>The mean detorque force was 13.4±1.94 in the non-lubricated group and 16.35± 1.24 in the lubricated group, which was significantly higher in the lubricated group (<i>p</i>< 0.001). Other results of the study include the non-significance of the difference in detorque force within male and female groups (<i>p</i>> 0.05), as well as the non-significance of Pearson's correlation between patients' age and detorque force (<i>p</i>> 0.05).</p><p><strong>Conclusion: </strong>According to the results, the use of lubricant significantly increases the detorque force, and it is recommended to use tetracycline eye ointment as a lubricant in implant treatment processes.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 2","pages":"145-150"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of the Incorporation of Nano-Hydroxyapatite on Physico-Chemical Properties of Calcium-Enriched Mixed Cement.","authors":"Mohammadreza Nabavizadeh, Yasser Samadi, Safoora Sahebi, Fateme Eskandari","doi":"10.30476/dentjods.2024.101837.2319","DOIUrl":"10.30476/dentjods.2024.101837.2319","url":null,"abstract":"<p><strong>Background: </strong>Calcium-enriched mixed (CEM) cement, though beneficial in endodontic applications, requires improvements in its physico-chemical properties to enhance clinical outcomes.</p><p><strong>Purpose: </strong>This study was conceptualized to investigate the impact of incorporating nano-hydroxyapatite (nHAP) on the physico-chemical properties of CEM cement.</p><p><strong>Materials and method: </strong>In this experimental study, nHAP powder at 5 and 10 wt% ratio was thoroughly mixed with CEM cement powder. Then they were mixed with a ratio of 1 g of powder to 0.33g of liquid and placed in special molds for each test. CEM cement without nHAP was used as a control sample. Samples were assessed for setting time, compressive strength, solubility, and pH.</p><p><strong>Results: </strong>According to our results, the addition of 5% nHAP significantly increased the initial setting time (S1) and compressive strength after 24 hours, while the addition of 5% and 10% nHAP significantly enhanced the pH of the CEM cement.</p><p><strong>Conclusion: </strong>Incorporation of 5% nHAP to CEM cement, although delayed S1 of this cement, but increased the pH level of CEM cement, which in turn could potentially improve the antimicrobial properties of CEM cement. Furthermore, the addition of 5% nHAP to CEM cement notably improved the compressive strength in the short term, which can be beneficial in withstanding the chewing forces after applying the cement in the oral environment. It is recommended to select an appropriate concentration of nHAP to optimize the properties of CEM cement based on the findings of this study.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"26 2","pages":"177-185"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}