{"title":"Exploring the Feasibility of P7 Medicine Principles in Dental Practice (P7 Dentistry).","authors":"Milad Saeedzadeh, Shahram Hamedani, Saeed Nemati","doi":"10.30476/dentjods.2025.108949.2858","DOIUrl":"https://doi.org/10.30476/dentjods.2025.108949.2858","url":null,"abstract":"","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"27 4","pages":"93-94"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147701150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oncocytoma of Palate: A Case Report, with an Emphasis on Immunohistochemistry.","authors":"Shubhangi Mani, Amit Mani, Vandana Pandey Tripathi, Manas Bajpai, Shyam Reddy Karakalla","doi":"10.30476/dentjods.2025.105376.2591","DOIUrl":"https://doi.org/10.30476/dentjods.2025.105376.2591","url":null,"abstract":"<p><p>Oncocytomas are benign tumors of salivary glands, characterized histopathologically by large epithelial cells with bright and eosinophilic cytoplasm. They occur mostly in parotid glands, with only a small percentage of these tumors occurring in minor salivary glands of buccal, mucosa, palate, maxillary sinus, and tonsillar fossa. They occur primarily in people older than 50 years and generally have a female predilection. Few authors have suggested that oncocytomas of minor salivary glands are more aggressive in nature in comparison to their major salivary gland counterparts. An exhaustive literature review of English language literature revealed 20 cases of minor salivary glands; hence, the present case is 21st case of minor salivary gland oncocytoma. We report a case of palatal oncocytoma in a 31-year-old male which was provisionally diagnosed as pleomorphic adenoma and also describe the immunohistochemical characteristics of this rare tumor of minor salivary glands.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"27 4","pages":"80-84"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147701088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iman Mohammadi, Forooz Keshani, Bahareh Fattahi, Mohammad Mehdi Soltani, Arman Roghani
{"title":"Chondroblastic Osteosarcoma of the Palate: A Rare Case Report with Diagnostic Considerations.","authors":"Iman Mohammadi, Forooz Keshani, Bahareh Fattahi, Mohammad Mehdi Soltani, Arman Roghani","doi":"10.30476/dentjods.2025.104234.2511","DOIUrl":"https://doi.org/10.30476/dentjods.2025.104234.2511","url":null,"abstract":"<p><p>Osteosarcoma is a rare and highly malignant primary bone tumor that infrequently occurs in the maxillofacial region. Among these, maxillary osteosarcomas are uncommon, and their occurrence in the palatal region is exceptionally rare, with fewer than five cases reported to date. Chondroblastic osteosarcoma, a subtype characterized by cartilaginous and osteoid components, poses diagnostic challenges due to its histological similarities with other cartilaginous tumors. This study presents a 35-year-old female referred to the Department of Oral and Maxillofacial Surgery at Isfahan University of Medical Sciences with a one-month history of palatal pain and swelling which worsened during eating. Clinical examination revealed a firm, ulcerated mass on the right side of the hard palate, clinically mimicking oral squamous cell carcinoma or salivary gland neoplasms. Radiographic evaluation using cone-beam computed tomography (CBCT) revealed an ill-defined, mixed-density lesion with a moth-eaten appearance, cortical bone destruction, and root resorption of adjacent teeth- features suggestive of an aggressive malignancy. Histopathological examination confirmed the diagnosis of chondroblastic osteosarcoma, a rare histologic subtype characterized by malignant cells producing both osteoid and cartilaginous matrix. Given its resemblance to other cartilaginous tumors, particularly chondrosarcoma, this subtype presents significant diagnostic challenges. The patient underwent hemimaxillectomy, followed by adjuvant chemotherapy. Intraoperative frozen section pathology was used to confirm tumor-free surgical margins- an essential step in reducing recurrence risk. This case underscores the importance of a multidisciplinary approach in the diagnosis and management of rare craniofacial malignancies such as chondroblastic osteosarcoma. Early recognition, accurate diagnosis, and prompt aggressive treatment are crucial for improving patient prognosis and reducing recurrence in such complex and rare presentations.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"27 4","pages":"85-92"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammadsaleh Khaghaninejad, Mohammad Dehghani, Farhad Ghorbani, Banafsheh Salehi
{"title":"Changes in Orbital Volume following Reconstruction with Alloplastic Materials in Patients with Orbital Trauma.","authors":"Mohammadsaleh Khaghaninejad, Mohammad Dehghani, Farhad Ghorbani, Banafsheh Salehi","doi":"10.30476/dentjods.2025.104766.2549","DOIUrl":"https://doi.org/10.30476/dentjods.2025.104766.2549","url":null,"abstract":"<p><strong>Background: </strong>Internal orbital reconstruction is a commonly performed procedure in management of zygomaticomaxillary complex (ZMC) fractures; however, it is not indicated in all cases. In management of orbital trauma, surgeons should not only correct the apparent defects, but also must reinstate the function of the orbit.</p><p><strong>Purpose: </strong>This study aimed to assess the changes in the orbital volume following reconstruction with alloplastic materials in patients with orbital trauma.</p><p><strong>Materials and method: </strong>This retrospective study evaluated all patients with unilateral orbital fracture presenting to the Oral and Maxillofacial Surgery Department of Rajaie Hospital (from 2013 to 2016, Shiraz, Iran) who underwent corrective surgery. The computed tomography (CT) scans of patients were analyzed by Volumetry software to quantify the change in the orbital volume after surgical reconstruction of the orbital floor with alloplastic materials compared with the sound contralateral orbit. Data were analyzed using the Chi-square test and Student t-test (alpha=0.05).</p><p><strong>Results: </strong>Significant differences were found in the volume of the traumatized orbit with sound contralateral orbit and the orbital volume after corrective surgery (p Value< 0.05). Corrective surgery was successful in all patients, and the orbital volume after treatment had no significant difference with the volume of the sound contralateral orbit (p> 0.05).</p><p><strong>Conclusion: </strong>Corrective surgery with alloplastic materials can successfully regain the orbital volume in patients with orbital floor fracture, with no significant difference with the volume of the sound contralateral orbit.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"27 4","pages":"48-53"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147701022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mostafa Sheikhi, Mohaddeseh Nasiri, Masoomeh Amani, Leila Abdolhosseinzadeh, Faezeh Zamani
{"title":"Evaluation of the Relationship between Maxillary and Mandibular Third Molar Impaction and Vertical and Anteroposterior Dimensions of the Face.","authors":"Mostafa Sheikhi, Mohaddeseh Nasiri, Masoomeh Amani, Leila Abdolhosseinzadeh, Faezeh Zamani","doi":"10.30476/dentjods.2025.104327.2519","DOIUrl":"https://doi.org/10.30476/dentjods.2025.104327.2519","url":null,"abstract":"<p><strong>Background: </strong>The impaction of the third molar is associated with specific facial skeletal and dental characteristics. Therefore, determining the type of facial skeletal growth may help predict third molar impaction and assist in treatment planning.</p><p><strong>Purpose: </strong>This study aimed to investigate the correlation between the impaction of the maxillary and mandibular third molars with the vertical and anteroposterior dimensions of the face, as well as to examine the prevalence and type of impaction.</p><p><strong>Materials and method: </strong>In this descriptive-analytical study, panoramic and lateral cephalometric radiographs of 200 patients who were referred to a radiology center in Zanjan were examined. The position, angle, and type of impaction were evaluated on the panoramic radiographs, and the type of vertical and anteroposterior facial profile was determined through lateral cephalometry. Finally, the correlation between impaction and the type of facial profile was analyzed with the Chi-Square test at a significance level of 0.05.</p><p><strong>Results: </strong>The prevalence of third molar impaction was higher in patients with skeletal Class II and those with a dolichofacial profile (55.5% and 63.5%). Class B, Class II, and mesioangular impactions were more common in the mandible, whereas Class C and distoangular impactions were more prevalent in the maxilla. The level of third molar impaction in the mandible was significantly related to the vertical dimension of the face (<i>p</i>= 0.003). The angle of impaction in the mandible was significantly associated with both the vertical and anteroposterior dimensions of the face (<i>p</i>= 0.036 and <i>p</i>= 0.014).</p><p><strong>Conclusion: </strong>The findings of this study can be beneficial in orthodontics for evaluating the impact of third molar impaction on dental crowding and facilitating the development of appropriate treatment plans. Knowing which individuals are more susceptible to third molar impaction enables specialists to implement early interventions. Additionally, timely referrals to oral and maxillofacial surgeons can be made when necessary.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"27 4","pages":"62-69"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147701105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Impact of Age on the Accuracy of Sexual Dimorphism Using Anthropometric Indices of Maxillary Sinus.","authors":"Najmeh Movahhedian, Leila Gharemani, Fatemeh Akbarizadeh, Leila Khojastepour","doi":"10.30476/dentjods.2025.104945.2561","DOIUrl":"https://doi.org/10.30476/dentjods.2025.104945.2561","url":null,"abstract":"<p><strong>Background: </strong>The potential benefit of maxillary sinus measurements for analysis of sexual dimorphism has been proved. Also, it has been shown that maxillary sinus dimensions, as the reliable sex indicators, diminish with age due to physiological and morphological alterations.</p><p><strong>Purpose: </strong>This study aimed to evaluate the effect of age on the accuracy of maxillary sinus indices for sex determination.</p><p><strong>Materials and method: </strong>In this cross-sectional study's research 240 cone beam computed tomography (CBCT) scans (120 males, 120 females), aged 20-70 years old, were evaluated retrospectively. Subjects were categorized into four age groups: 20-29, 30-39, 40-49, and ≥50 years. Each group consisted of 60 subjects. Maximum sinus height, width, length, and distance between two maxillary sinuses were evaluated.</p><p><strong>Results: </strong>All the measurements were higher in men than in women. Generally, the strongest sex indicator was maxillary sinus width However, when analyzing different age groups, the most reliable indicators for determining sex were the distance between the sinuses in the 20-29 age group, sinus height in the 40-49 group, and sinus width in both the 30-39 and 50-and-above age groups. The specific sex discriminant formula showed an accuracy of 78.3% for the ages of 20-29 and 40-49 years as well as 71.7% for the 30-39 and ≥50 age groups.</p><p><strong>Conclusion: </strong>The specific sex discriminant formula presented in this study showed noticeable accuracies for sex determination. Additionally, discriminant analysis revealed that the anthropometric measurements of the maxillary sinus exhibit varying degrees of sexual dimorphism across different age groups.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"27 4","pages":"18-26"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147701131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Farhadi, Ali Dehghani Nazhvani, Fatemeh Faghihi, Mohammad Hadi Khademi, Hasan Rezazadeh
{"title":"Investigating the Relationship Human Parvovirus B19 Infection in Benign and Malignant Salivary Gland Tumors.","authors":"Ali Farhadi, Ali Dehghani Nazhvani, Fatemeh Faghihi, Mohammad Hadi Khademi, Hasan Rezazadeh","doi":"10.30476/dentjods.2025.102008.2330","DOIUrl":"https://doi.org/10.30476/dentjods.2025.102008.2330","url":null,"abstract":"<p><strong>Background: </strong>Parvovirus B19 is a common virus that can affect everyone, especially immunocompromised patients. The virus is present in various leukemias and solid tumors, and several B19-related diseases including autoimmune disorders, hepatitis, vasculitis, acute and chronic inflammatory diseases, and some thyroid cancers have been described.</p><p><strong>Purpose: </strong>This investigation aimed to quantify the frequency of human Parvovirus-B19 infection in salivary gland tumors, both benign and malignant.</p><p><strong>Materials and method: </strong>In this cross-sectional study, 71 formalin-fixed, paraffin-embedded tissue specimens associated with benign and malignant salivary gland tumors, along with tissues from 30 normal salivary glands from the maxillofacial pathology laboratory of Shiraz Dental School, Chamran, and Rajai teaching hospitals (the main two major referral centers), were examined using nested-PCR to determine if B19 DNA was present. All data, including age, sex, location, and the presence of the virus, were considered, presented in tables, and statistically analyzed. The prevalence of B19 was compared to the normal salivary gland group.</p><p><strong>Results: </strong>B19 DNA was identified in 11 specimens (15.5%) out of the 71 available specimens from the patient group. None of the specimens from the normal salivary gland group tested positive for B19 DNA. Consequently, the prevalence of B19 in the patient group was significantly higher than that in the normal salivary gland group (<i>p</i> Value = 0.031). There was no significant relationship between age, sex, location, type of tumor, and the presence of B19 infection.</p><p><strong>Conclusion: </strong>Our results indicated a relationship between the presence of B19 parvovirus in the patient group compared to that in the control groups. Based on our study's findings, it can be assumed that B19 virus is likely to be presenting in both benign and malignant salivary gland tumors.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"27 4","pages":"43-47"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147701072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Kami, Marie Saghaeian Jazi, Mostafa Allahyari, Elham Fakhari
{"title":"Association of Vitamin D Receptor Gene Polymorphisms with Periodontitis.","authors":"Mohammad Kami, Marie Saghaeian Jazi, Mostafa Allahyari, Elham Fakhari","doi":"10.30476/dentjods.2025.103866.2485","DOIUrl":"https://doi.org/10.30476/dentjods.2025.103866.2485","url":null,"abstract":"<p><strong>Background: </strong>Considering the role of vitamin D in regulation of the bone metabolism and the immune system, some have suggested the effect of vitamin D receptor gene polymorphism in susceptibility to periodontitis.</p><p><strong>Purpose: </strong>We aimed to determine the association between vitamin D receptor (VDR) gene polymorphisms <i>Fok1</i>, <i>Apa1</i>, <i>Bsm1</i>, and <i>Taq1</i> and periodontitis.</p><p><strong>Materials and method: </strong>In this case-control study, 51 patients with stage Ⅲ periodontitis (case group) and 51 without (control group) were enrolled. Blood samples were taken to analyze the single nucleotide polymorphism (SNP) using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) after DNA extraction. Finally, the data were analyzed using SPSS software version 17, SNPStats, using Chi-square and t-test.</p><p><strong>Results: </strong>The allelic frequencies of SNP1 (<i>TaqI</i>) (<i>p</i> Value=0.089), SNP2 (<i>ApaI</i>) (<i>p</i>= 0.481), SNP3 (<i>BsmI</i>) (<i>p</i>= 0.566), and SNP4 (<i>FokI</i>) (<i>p</i>= 0.658) were not different between the groups. Genotype frequencies in the four hereditary models of codominant, dominant, recessive and, overdominant were not different in any SNPs. Of 12 haplotypes identified in the study population, TCbF was most frequent in the case group and tABF in the control group (<i>p</i>> 0.05).</p><p><strong>Conclusion: </strong>No significant association was found between VDR gene polymorphisms and periodontitis.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"27 4","pages":"33-42"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of Voids in the Apical Plug of MTA Using Cone-Beam Computed Tomography, Digital Radiography, and Analog Radiography.","authors":"Mahsa Eskandarinezhad, Sedighe Razi, Tirdad Pirzadeh, Sabete Bagheri Sabzevar, Leyla Nazari, Salehe Akhondian","doi":"10.30476/dentjods.2025.104334.2520","DOIUrl":"https://doi.org/10.30476/dentjods.2025.104334.2520","url":null,"abstract":"<p><strong>Background: </strong>Achieving a satisfactory apical seal in root canals with open apices can be challenging, with the risk of filling material extrusion into the apex. Timely detection of voids in root canal filling material is crucial to prevent complications.</p><p><strong>Purpose: </strong>This study aimed to compare the accuracy of cone-beam computed tomography (CBCT), digital radiography, and conventional radiography in detecting voids in mineral trioxide aggregate (MTA) apical plugs.</p><p><strong>Materials and method: </strong>In this in vitro study, thirty-two extracted upper maxillary incisors underwent decoronation, root canal instrumentation, and simulation of an apexification model for open apex teeth. The samples were then divided into two groups (n=16) based on void sizes including group A in which MTA was compacted manually as an apical plug, and group B in which MTA apical plug was made with simulated voids using an 0.4-mm diameter needle. CBCT, digital, and analog radiography scans were performed on all samples. The images were assessed by an endodontist and a radiologist to identify the presence of voids. The accuracy of the three methods in detecting voids in MTA apical plugs was evaluated using Chi-square analysis.</p><p><strong>Results: </strong>CBCT (43.8%) showed superior detection of small voids (group A) compared to analog (37.5%) and digital (18.7%) radiography methods, with analog radiography being more effective than digital radiography (<i>p</i>= 0.037). For large void detection (group B), digital radiography (94%) outperformed the other methods, while analog (81.3%) and CBCT (81.3%) techniques exhibited similar diagnostic abilities (<i>p</i>= 0.034). The significance level was set at <i>p</i>< 0.05.</p><p><strong>Conclusion: </strong>CBCT imaging is more effective than analog radiography for detecting small voids, and both methods outperform digital radiography, likely due to CBCT's three-dimensional imaging capabilities. In diagnosing large voids, digital radiography showed higher accuracy than the other techniques, while CBCT and analog radiography had similar diagnostic abilities. Variations in image processing and radiation doses used might account for the differences between these techniques.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"27 4","pages":"27-32"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147701064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abbas Abbaszadegan, Alireza Adl, Fateme Nemati, Nikta Ranjbar
{"title":"The Effect of Different Rotary Systems on Creating Intracanal Dentinal Defects: An <i>Ex Vivo</i> Study.","authors":"Abbas Abbaszadegan, Alireza Adl, Fateme Nemati, Nikta Ranjbar","doi":"10.30476/dentjods.2025.103410.2449","DOIUrl":"https://doi.org/10.30476/dentjods.2025.103410.2449","url":null,"abstract":"<p><strong>Background: </strong>The creation of intracanal dentinal defects during root canal preparation is a concern in endodontic treatment; as such defects can compromise the integrity of the tooth and potentially lead to fractures or failure of the treatment. Rotary systems, commonly used for shaping root canals, vary in their design, material, and cutting mechanisms, which may influence the extent of dentinal defects they induce. However, the comparative impact of different rotary systems on the formation of these defects remains unclear.</p><p><strong>Purpose: </strong>The aim of this <i>ex vivo</i> study was to compare the effects of four rotary systems (One-curve, One-shape, Neolix, and ProTaper Universal) on the creation of intracanal dentinal defects in extracted human teeth.</p><p><strong>Materials and method: </strong>In this <i>ex vivo</i> study, seventy extracted human mandibular incisor teeth with straight roots and no extra canals or existing dentinal defects were selected and randomly divided into five groups, including one control group and four experimental groups. In the control group (n=10), no instrumentation was performed. In the experimental groups (n=15 each), instrumentation was done using the rotary systems ProTaper Universal, Neolix, One-shape, and One-curve, respectively. All groups received the same amount of irrigation: 12mL of 2% sodium hypochlorite followed by 3mL of sterile saline. The roots were then horizontally sectioned at 3, 6, and 9 mm from the apex and evaluated under a stereomicroscope for the presence of intracanal defects. Data were analyzed using Chi-square test.</p><p><strong>Results: </strong>The lowest and highest rates of dentinal cracks were observed in the One-curve and One-shape groups, respectively. No significant differences were observed among the experimental groups (<i>p</i> Value=0.46).</p><p><strong>Conclusion: </strong>All tested rotary systems induced dentinal defects. The lowest and highest incidence of dentinal defects occurred in teeth prepared using the One-curve (26%) and One-shape (53%) rotary instruments, respectively.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"27 4","pages":"13-17"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147701118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}