Hygiene and environmental health advances最新文献

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Sex and age characteristics of thunderstorm asthma emergency department visits 雷暴哮喘急诊就诊者的性别和年龄特征
Hygiene and environmental health advances Pub Date : 2024-07-17 DOI: 10.1016/j.heha.2024.100099
M. Luke Smith , Richard F. MacLehose , Chris H. Wendt , Jesse D. Berman
{"title":"Sex and age characteristics of thunderstorm asthma emergency department visits","authors":"M. Luke Smith ,&nbsp;Richard F. MacLehose ,&nbsp;Chris H. Wendt ,&nbsp;Jesse D. Berman","doi":"10.1016/j.heha.2024.100099","DOIUrl":"10.1016/j.heha.2024.100099","url":null,"abstract":"<div><p>Severe asthma has been shown to occur in the combined presence of high pollen and thunderstorm conditions, also known as ‘thunderstorm asthma.’ First studied as severe epidemic events, recent longitudinal work studied less dramatic but more frequent occurrences. We explore thunderstorm asthma-related emergency department visits in the Minneapolis-St. Paul metropolitan area and evaluated risk differences by sex and age. We define a thunderstorm asthma exposure event as the daily occurrence of 2 or more lightning strikes during high pollen periods, and use daily counts of asthma-related emergency department visits to estimate relative and absolute risk of severe asthma during thunderstorm asthma events for the full population and for sex and age subgroups. The overall population had a 1.06 (95 % CI: 1.02, 1.09) times higher risk of asthma-related ED visits during thunderstorm asthma events compared to days without thunderstorm asthma events. Children under 18 show no higher risk (RR 1.02; 95 % CI: 0.97 1.08), but adults 18–44 years (RR 1.08; 95 % CI: 1.02, 1.13) and 45 and up (RR 1.08; 95 % CI 1.02, 1.15) show higher relative risk. Absolute risk measures show similar patterns to the age and sex results, but age-sex subgroups show more variation in absolute vs relative risk. Our results support an association between ED visits and thunderstorm asthma and provide evidence of varying risks by sex across the life course. These differences in risk have implications for clinical treatment of this allergic type of asthma and for future research into this poorly recognized environmental exposure.</p><p>Plain Language Summary: Recent research has highlighted the existence of Thunderstorm asthma events, a phenomenon in which pollen grains rupture in the conditions that occur with a thunderstorm, releasing sub-pollen particles that are capable of triggering severe asthma in susceptible populations. Where severe asthma is a disease that usually impacts children, we find in this study that asthma ED visits associated with thunderstorm asthma events more frequently impact adults, particularly males 18–44 and females 45 and up.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"11 ","pages":"Article 100099"},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000126/pdfft?md5=2069b0fa0173b6a2621c5feba8aca92e&pid=1-s2.0-S2773049224000126-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141846378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations of endocrine disrupting chemicals with renal function in older individuals 干扰内分泌的化学品与老年人肾功能的关系
Hygiene and environmental health advances Pub Date : 2024-07-09 DOI: 10.1016/j.heha.2024.100098
Jiaoyang Chen , Yue Wang , Zhixin Zhao , Ye Deng , Tianyun Wang , Yuting Xiang , Yuting Wang , Jiamei Chen , Miao He
{"title":"Associations of endocrine disrupting chemicals with renal function in older individuals","authors":"Jiaoyang Chen ,&nbsp;Yue Wang ,&nbsp;Zhixin Zhao ,&nbsp;Ye Deng ,&nbsp;Tianyun Wang ,&nbsp;Yuting Xiang ,&nbsp;Yuting Wang ,&nbsp;Jiamei Chen ,&nbsp;Miao He","doi":"10.1016/j.heha.2024.100098","DOIUrl":"10.1016/j.heha.2024.100098","url":null,"abstract":"<div><h3>Background</h3><p>Since the twentieth century, endocrine-disrupting substances (EDCs) such as phthalates and organophosphates have been utilised in various goods. The long-term usage of these products may have negative effects on people's health. Most EDCs are metabolized through kidneys, but there are few research investigating renal damage from exposure to EDCs in the elderly. This study aims to examine the effects of EDCs exposure on renal function in the elderly population.</p></div><div><h3>Methods</h3><p>In this cross-sectional study, a total of 200 elder from a community in northeast China were enrolled. All subjects were investigated by questionnaire, physical examination, and biological sample collection. Estimated glomerular filtration rate (eGFR) was used to classify renal function group. Lasso regression was used to screen out the EDCs related to renal function. After covariate adjustment, binary logistic regression was used to analyze the relationship between decreased renal function and EDCs. Weighted quantile sum (WQS) regression was used to assess the association of combined-EDCs with decreased renal function, subgroup analyses were performed to identify potentially sensitive populations to the effects of EDCs on decreased renal function.</p></div><div><h3>Results</h3><p>Binary logistic regression showed that 3,5-di-tert-butyl-4-hydroxybenzoic acid (BHT-COOH), Mono(3-carboxypropyl) phthalate (MCPP), and Methyl paraben (MeP) were negatively associated with decreased renal function, with odds ratio (OR) and 95% confidence intervals of 0.591 (0.366, 0.954), 0.990 (0.981, 0.999) and 0.997 (0.995, 0.999), respectively. WQS regression found DPP (Weights = 22.5%) to have the greatest effect on decreased renal function in the elderly. Moreover, significant potential interactions were observed among MEHP&amp;MOcP with hypertension on decreased renal function (<em>P</em><sub>interaction</sub> = 0.014), as well as BPS and MEHP&amp;MocP with Overweight/obesity on decreased renal function (<em>P</em><sub>interaction</sub> = 0.032, 0.024).</p></div><div><h3>Conclusions</h3><p>BHT-COOH, MCPP, and MeP were negatively associated with decreased renal function in the elderly. Elders with hypertension and who are overweight /obesity may be more sensitive to EDCs.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"11 ","pages":"Article 100098"},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000114/pdfft?md5=081838dccf4e3b0f93d1a1e22127a1ae&pid=1-s2.0-S2773049224000114-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141637343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the association between PM2.5 concentration and hospital admissions for pediatric asthma in Ho Chi Minh City, Viet Nam 评估越南胡志明市 PM2.5 浓度与小儿哮喘入院率之间的关系
Hygiene and environmental health advances Pub Date : 2024-07-02 DOI: 10.1016/j.heha.2024.100097
Tinh Huu Ho , Chinh Van Dang , Thao Thi Bich Pham , Hien Thi Thu Ngo , Supat Wangwongwatana
{"title":"Assessment of the association between PM2.5 concentration and hospital admissions for pediatric asthma in Ho Chi Minh City, Viet Nam","authors":"Tinh Huu Ho ,&nbsp;Chinh Van Dang ,&nbsp;Thao Thi Bich Pham ,&nbsp;Hien Thi Thu Ngo ,&nbsp;Supat Wangwongwatana","doi":"10.1016/j.heha.2024.100097","DOIUrl":"https://doi.org/10.1016/j.heha.2024.100097","url":null,"abstract":"<div><p>Despite the growing concern over the impact of ambient fine particulate matter (PM<sub>2.5</sub>) on respiratory health, studies on the association between PM<sub>2.5</sub> and childhood asthma in Vietnam have remained relatively sparse.</p><p>The study aimed to evaluate the short-term effects of PM<sub>2.5</sub> on asthma hospital admissions in Ho Chi Minh City (HCMC), the most populous city in Vietnam. The PM<sub>2.5</sub> database from 2016 to 2019 was collected at two fixed monitoring stations. The health database was collected from all three children's hospitals. A time-series regression analysis was conducted to examine the associations between the daily PM<sub>2.5</sub> concentration and hospitalizations for asthma.</p><p>A total of 11,223 records of children under five years old hospitalized for asthma were collected, of which 64 % were male and 70 % were aged 2 to under five years old. The daily mean PM<sub>2.5</sub> concentration over the study period was 28.2 μg/m<sup>3</sup>. Each 10 μg/m<sup>3</sup> increase in PM<sub>2.5</sub> at lag<sub>2</sub>, lag<sub>3,</sub> and lag<sub>04</sub>, we found that the excess risk of total asthma hospital admission was 2.71 %, 2.63 %, and 3.9 %, respectively. According to the subgroup analysis, female gender and children aged from two to under five years had more significant effects.</p><p>PM<sub>2.5</sub> poses a risk to children's health; therefore, the local authority should prioritize improving the air quality.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"11 ","pages":"Article 100097"},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000102/pdfft?md5=487e0ffd0276fd44abd429d71af22baa&pid=1-s2.0-S2773049224000102-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In the wake of a surge in naegleria fowleri infections: Overcoming challenges and implementing protective measures in Pakistan 在嗜血杆菌感染激增之后:克服挑战并在巴基斯坦实施保护措施
Hygiene and environmental health advances Pub Date : 2024-05-09 DOI: 10.1016/j.heha.2024.100095
Juvairia Yousuf, Laiba Afaq, Uzma Aslam, Nabahat Shafi, Zainab Syyeda Rahmat
{"title":"In the wake of a surge in naegleria fowleri infections: Overcoming challenges and implementing protective measures in Pakistan","authors":"Juvairia Yousuf,&nbsp;Laiba Afaq,&nbsp;Uzma Aslam,&nbsp;Nabahat Shafi,&nbsp;Zainab Syyeda Rahmat","doi":"10.1016/j.heha.2024.100095","DOIUrl":"https://doi.org/10.1016/j.heha.2024.100095","url":null,"abstract":"","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"10 ","pages":"Article 100095"},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000084/pdfft?md5=7f3e86ea42590709e3aef105dfa2b95c&pid=1-s2.0-S2773049224000084-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140950313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association between metal exposure and body mass index of preschool children of Shaanxi, China 中国陕西学龄前儿童金属暴露与体重指数的关系
Hygiene and environmental health advances Pub Date : 2024-05-07 DOI: 10.1016/j.heha.2024.100094
Yan Zhao , Zhaoyang Li , Xinyue Wen , Hongqiu Li , Huifang He , Jing Han
{"title":"The association between metal exposure and body mass index of preschool children of Shaanxi, China","authors":"Yan Zhao ,&nbsp;Zhaoyang Li ,&nbsp;Xinyue Wen ,&nbsp;Hongqiu Li ,&nbsp;Huifang He ,&nbsp;Jing Han","doi":"10.1016/j.heha.2024.100094","DOIUrl":"10.1016/j.heha.2024.100094","url":null,"abstract":"<div><p>There are few studies on the association between polymetallic exposure and obesity in preschool children, and the conclusions are inconsistent. The study aimed to explore the association between urine metals and body mass index (BMI). For 342 preschool children in the industrial park of Shaanxi, China, uniformly trained investigators collected basic information of preschoolers and measured height and weight. Morning urine were collected, and BMI were calculated. We measured concentrations of 22 urine metals by quadrupole inductively coupled plasma-mass spectrometry (ICP-MS).</p><p>The least absolute shrinkage and selective operator (LASSO) regression model was used to screen urine metals larger impact on BMI. In the polymetallic exposure model, generalized linear regression was used to explore the relationship between the selected urine metals and BMI. The overall relationship between urine metals and BMI was analyzed using restricted cubic spline (RCS). The interaction method was used to explore the influence of metal-metal interaction on BMI. After adjustment for covariates, ln-transformed urinary copper (Cu) levels and urinary molybdenum (Mo) levels were negatively associated with BMI, (Cu, β=−1.219, 95% CI: −2.047, −0.391, <em>P</em>&lt;0.05; Mo, β=−0.797, 95% CI: −1.508, −0.087, <em>P</em>&lt;0.05). Polymetallic model showed similar results. Both ln-transformed urinary Cu levels and urinary Mo levels were negatively correlated with BMI (Cu: β=−1.556, 95% CI: −2.488, −0.624, <em>P</em>&lt;0.05; Mo: β=−0.915, 95% CI: −1.817, −0.013, <em>P</em>&lt;0.05). The results of RCS visually demonstrate that Cu and BMI are non-linearly correlated (<em>P</em> <sub>total</sub> &lt; 0.001, <em>P</em> <sub>nonliearity</sub> = 0.005), Mo and BMI are linearly correlated (<em>P</em> <sub>total</sub> &lt; 0.05, <em>P</em> <sub>nonliearity</sub> = 0.099) Urinary Cu was negatively correlated with BMI nonlinearly in preschool children, and there was a borderline interaction between urinary Mo and Cu levels.</p><p>Further researches are needed to validate these associations and reveal underlying mechanisms</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"10 ","pages":"Article 100094"},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000072/pdfft?md5=d82dff54982235e51c7423cc0d6bc773&pid=1-s2.0-S2773049224000072-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141048416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salmonella Typhimurium outbreak caused by contaminated chocolate highlights the importance of food hygiene and a socially responsible food chain 受污染巧克力引发的鼠伤寒沙门氏菌疫情凸显了食品卫生和对社会负责的食物链的重要性
Hygiene and environmental health advances Pub Date : 2024-05-07 DOI: 10.1016/j.heha.2024.100096
Hannu Korkeala , Tarja Koskela , Katri Jalava
{"title":"Salmonella Typhimurium outbreak caused by contaminated chocolate highlights the importance of food hygiene and a socially responsible food chain","authors":"Hannu Korkeala ,&nbsp;Tarja Koskela ,&nbsp;Katri Jalava","doi":"10.1016/j.heha.2024.100096","DOIUrl":"https://doi.org/10.1016/j.heha.2024.100096","url":null,"abstract":"<div><p>Recent global salmonella outbreak was linked to chocolate products but potential role of cocoa beans has been neglected. Chocolate related salmonella outbreaks have occurred mostly during low cocoa price levels. Food business operators should ensure hygiene at all production stages. These outbreaks highlight corporate social responsibility while demonstrating the need of multi-professional approaches.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"10 ","pages":"Article 100096"},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000096/pdfft?md5=e8ae9bc974fc0de81c6175b100e0fae3&pid=1-s2.0-S2773049224000096-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140952408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coal-fired PM2.5 induces endothelial cell injury and the expression of atherosclerosis-related adhesion molecules: Involvement of the p38 and JNK signaling pathways 燃煤产生的 PM2.5 会诱导内皮细胞损伤和动脉粥样硬化相关粘附分子的表达:p38和JNK信号通路的参与
Hygiene and environmental health advances Pub Date : 2024-04-16 DOI: 10.1016/j.heha.2024.100093
Yanping Zhang , Hanyun Zheng , Siqi Wang , Xuetao Wei , Qin Li , Feifei Wang
{"title":"Coal-fired PM2.5 induces endothelial cell injury and the expression of atherosclerosis-related adhesion molecules: Involvement of the p38 and JNK signaling pathways","authors":"Yanping Zhang ,&nbsp;Hanyun Zheng ,&nbsp;Siqi Wang ,&nbsp;Xuetao Wei ,&nbsp;Qin Li ,&nbsp;Feifei Wang","doi":"10.1016/j.heha.2024.100093","DOIUrl":"10.1016/j.heha.2024.100093","url":null,"abstract":"<div><p>It has been reported that PM<sub>2.5</sub> causes endothelial cell injury and promotes atherosclerosis. However, the exact mechanism through which coal-fired PM<sub>2.5</sub> induces endothelial cell injury, and the involvement of the p38 and JNK signaling pathways in this process remain unclear. In this study, EA.hy926 cells were exposed to coal-fired PM<sub>2.5</sub> at concentrations of 25, 50, and 100 μg/mL, and the toxic effects were observed. The phosphorylation of the JNK and p38 signaling pathways was investigated through western blot analysis. Additionally, the expression of adhesion molecules (ICAM-1 and E-selectin) was assessed using ELISA and flow cytometry. Changes in cellular toxicity and adhesion molecules were evaluated after pretreatment with the p38 inhibitor SB203580 (10 μM) and the JNK inhibitor SP600125 (25 μM). We observed that exposure to coal-fired PM<sub>2.5</sub> led to a decrease in cell survival rate and proliferation while promoting apoptosis. Exposure to coal-fired PM<sub>2.5</sub> promoted the expression of ICAM-1 and E-selectin, as well as the phosphorylation of p38 and JNK in EA.hy926 cells. After using p38 and JNK inhibitors, there was an observed increase in cell survival rate and proliferation, accompanied by a decrease in apoptosis. The levels of ICAM-1 and E-selectin showed no significant changes with the addition of p38 and JNK inhibitors. Our results indicated that coal-fired PM<sub>2.5</sub> caused cellular toxicity and increased the levels of ICAM-1 and E-selectin. The p38 and JNK signaling pathways might play a role in the reduction of cell viability, while the regulation of ICAM-1 and E-selectin might not be influenced by these pathways.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"10 ","pages":"Article 100093"},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000060/pdfft?md5=c729f6fa76ea09161f111e6d024e74cd&pid=1-s2.0-S2773049224000060-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140761194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex toys for pleasure, but there are risks: In silico toxicity studies of leached Micro/Nanoplastics and phthalates 性玩具能带来快乐,但也存在风险:浸出微/纳米塑料和邻苯二甲酸盐的硅学毒性研究
Hygiene and environmental health advances Pub Date : 2024-04-11 DOI: 10.1016/j.heha.2024.100092
Christian Ebere Enyoh, Qingyue Wang
{"title":"Sex toys for pleasure, but there are risks: In silico toxicity studies of leached Micro/Nanoplastics and phthalates","authors":"Christian Ebere Enyoh,&nbsp;Qingyue Wang","doi":"10.1016/j.heha.2024.100092","DOIUrl":"https://doi.org/10.1016/j.heha.2024.100092","url":null,"abstract":"<div><p>The widespread use of sex toys has sparked concerns about potential health risks associated with the leaching of micro/nanoplastics (M/NPs) and phthalates. In this <em>in silico</em> toxicity analysis, we investigated the immunotoxicity potential of compounds mechanically produced from sex toys. The research focuses on understanding their interactions with critical human cytochrome P450 enzymes (CYP34A and CYP2D6), which are central to drug metabolism and immune function. Four types of M/NPs (polyethylene terephthalate - PET, polyvinyl chloride - PVC, polydimethylsiloxane - PDMS, polyisoprene) and eight phthalates (Diethyl phthalate - DEP, Bis(4-methyl-2-pentyl) phthalate, Bis(2-methoxyethyl) phthalate, Benzyl butyl phthalate - BBP, Dibutyl Phthalate - DBP, Diethylhexyl phthalate - DEHP, Dinonyl phthalate - DNP, Di-n-octyl phthalate - DnOP) from sex toys were analyzed. Molecular dynamics and docking simulations were conducted to assess the binding affinity of these compounds to the enzymes. PET exhibited the highest toxicity, with a binding affinity of -8.3 kcal/mol and -8.9 kcal/mol for CYP3A4 and CYP2D6, respectively, surpassing control values (-7.8 kcal/mol and -6.3 kcal/mol). BBP showed considerable toxicity, binding strongly to CYP3A4 (-7.8 kcal/mol) and CYP2D6 (-9.1 kcal/mol). PDMS and DEP were the lowest toxic compounds in both groups. Molecular interactions revealed hydrogen bonds, pi interactions, and unfavorable donor-donor effects between compounds and specific amino acid residues within the enzymes. While these <em>in silico</em> findings provide insights, they underscore the need for comprehensive chemical analyses and absorption studies to validate health risks. This research emphasizes the necessity of evaluating the toxicity of M/NPs and phthalates from sex toys, promoting further investigations to protect individuals' health during product use.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"10 ","pages":"Article 100092"},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000059/pdfft?md5=a2252bdaaf9513a516dfe261d09dc81e&pid=1-s2.0-S2773049224000059-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140555786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exercise attenuates the association between pyrethroid exposure and sleep disorders in male adults 运动可减轻男性成年人接触拟除虫菊酯与睡眠障碍之间的关系
Hygiene and environmental health advances Pub Date : 2024-04-10 DOI: 10.1016/j.heha.2024.100091
Jing Shao , Jing Yang , Jia Lv , Tao Wang , Huiru Chen , Xinyu Zhang , Jingjing Li , Min Wang , Lihua Xu , Yichao Huang , Xiuhong Meng
{"title":"Exercise attenuates the association between pyrethroid exposure and sleep disorders in male adults","authors":"Jing Shao ,&nbsp;Jing Yang ,&nbsp;Jia Lv ,&nbsp;Tao Wang ,&nbsp;Huiru Chen ,&nbsp;Xinyu Zhang ,&nbsp;Jingjing Li ,&nbsp;Min Wang ,&nbsp;Lihua Xu ,&nbsp;Yichao Huang ,&nbsp;Xiuhong Meng","doi":"10.1016/j.heha.2024.100091","DOIUrl":"https://doi.org/10.1016/j.heha.2024.100091","url":null,"abstract":"<div><h3>Background</h3><p>Pyrethroids are widely used in agriculture and household pest management as one of the top three insecticides globally, yet the neurobehavioral impacts of human exposure to these chemicals have attracted increasing concern.</p></div><div><h3>Objective</h3><p>The purpose of this study was to examine the associations between pyrethroid exposure and sleep disorders and whether exercise could attenuate these associations.</p></div><div><h3>Methods</h3><p>We analyzed cross-sectional data from the 2007-2014 National Health and Nutrition Examination Survey to study the association between pyrethroid pesticide exposure and sleep disorders. The exposure level of pyrethroid metabolites in urine samples was measured. Physician diagnosis of sleep disorders was used to determine sleep disorders. Exercise level was judged by self-reported physical activity from the interviews.</p></div><div><h3>Results</h3><p>Of the 5947 participants, sleep disorders had a weighted prevalence of 9.0 %, representing an approximation of 186,140,757 patients nationwide. We found a sex-specific association between high levels of 3-PBA and elevated risk of sleep disorders diagnosis in men (OR: 1.87; 95 % CI: 1.150–3.042; <em>P</em> = 0.01). In addition, less physical activity was associated with higher rates of sleep disorders as pyrethroid exposure levels increased (OR: 1.98; 95 % CI: 1.152–3.388; <em>P</em> = 0.02).</p></div><div><h3>Conclusion</h3><p>This study further confirmed that pyrethroid exposure is associated with an elevated risk of sleep disorders in men. More importantly, we reported for the first time that vigorous physical activity attenuates the correlation between pyrethroid exposure and sleep disorders.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"10 ","pages":"Article 100091"},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000047/pdfft?md5=ca407c61ebfb2d5f28868cc8f2ac11d2&pid=1-s2.0-S2773049224000047-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140555783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blood lead levels in the general population and vulnerable sub-populations and related risk factors for lead exposure in Canada 加拿大普通人群和弱势亚人群的血铅水平以及铅暴露的相关风险因素
Hygiene and environmental health advances Pub Date : 2024-02-01 DOI: 10.1016/j.heha.2024.100088
Kathy C. Nguyen , Subramanian Karthikeyan , Ellen J.D. Lye , Huda Masoud , Janine Clarke , Julie L. Yome , Djordje Vladisavljevic , Laurie H.M. Chan , Annie St-Amand
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