Hygiene and environmental health advances最新文献

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Associations between exposure to multiple environmental chemicals and metabolic syndrome: A mixture analysis 接触多种环境化学物质与代谢综合征之间的关系:混合分析
Hygiene and environmental health advances Pub Date : 2024-10-05 DOI: 10.1016/j.heha.2024.100112
Ruiqiang Li , Xiaoyi Lin , Tingyu Lu , Jiao Wang , Ying Wang , Lin Xu
{"title":"Associations between exposure to multiple environmental chemicals and metabolic syndrome: A mixture analysis","authors":"Ruiqiang Li ,&nbsp;Xiaoyi Lin ,&nbsp;Tingyu Lu ,&nbsp;Jiao Wang ,&nbsp;Ying Wang ,&nbsp;Lin Xu","doi":"10.1016/j.heha.2024.100112","DOIUrl":"10.1016/j.heha.2024.100112","url":null,"abstract":"<div><div>Exposure to environmental chemicals is prevalent. While previous studies reported associations between multiple chemical exposures and metabolic syndrome (MetS), they did not comprehensively account for correlations among exposures. We used machine learning methods including Boruta algorithm and least absolute shrinkage and selection operator (LASSO) regression, combined with weighted quartiles sum (WQS) regression to investigate the associations of phenols, polycyclic aromatic hydrocarbons (PAHs), metals, and phthalates with MetS and its components. Data were drawn from the 2005–2012 National Health and Nutrition Examination Survey (NHANES). The mean (standard deviation (SD)) age of 2596 participants was 48.4 (17.9) years. After adjusting for age, sex, body mass index, race/ethnicity, marital status, education, poverty income ratio, physical activity, smoking, and alcohol, higher 2-Phenanthrene (2-PHE) and mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) concentrations were associated with a higher odds of the MetS (odds ratio (OR) = 4.26, 95 % confidence interval (CI) 2.40–7.58 per ng/mL, and 3.24, 1.75–6.02 per ng/L, respectively). WQS index for environmental chemicals was positively associated with the MetS (OR = 1.31, 95 % CI 1.09–1.57). Moreover, we observed consistent and stronger positive associations with MetS (OR = 1.54, 95 % CI 1.04–2.30) in current smokers. Exposure to phenols, PAHs, metals, and phthalates was positively associated with an increase in metabolic syndrome and its components, which was more pronounced in current smokers.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"12 ","pages":"Article 100112"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing the multi-dimensional effects of air pollution on maternal complications and birth outcomes: A structural equation modeling approach 评估空气污染对产妇并发症和分娩结局的多维影响:结构方程模型法
Hygiene and environmental health advances Pub Date : 2024-10-05 DOI: 10.1016/j.heha.2024.100113
Boubakari Ibrahimou , Ning Sun , Sophie Dabo-Niang
{"title":"Assessing the multi-dimensional effects of air pollution on maternal complications and birth outcomes: A structural equation modeling approach","authors":"Boubakari Ibrahimou ,&nbsp;Ning Sun ,&nbsp;Sophie Dabo-Niang","doi":"10.1016/j.heha.2024.100113","DOIUrl":"10.1016/j.heha.2024.100113","url":null,"abstract":"<div><h3>Objective</h3><div>This cross-sectional study aims to investigate the direct and indirect relationships between exposure to a metal mixture in air and adverse pregnancy outcomes across gestational stages.</div></div><div><h3>Methods</h3><div>With 46,829 births in 2021 in two Florida counties and Air Quality System data, structural equation modeling was used to construct latent metal mixtures in PM<sub>2.5</sub> and unravel their effects on pregnancy complications (preeclampsia and gestational diabetes) and birth outcomes (low birth weight and preterm birth risks).</div></div><div><h3>Results</h3><div>A latent variable featuring seven metals (Aluminum, Calcium, Iron, Magnesium, Manganese, Silicon, Vanadium) was identified through the measurement model. The latent metal mixture exposure had direct effects on gestational diabetes and preterm birth (1st trimester, 2nd trimester), low birth weight (1st trimester), and preeclampsia (2nd trimester). When considering total effects, the effects on low birth weight in the 1st trimester and on preeclampsia in 2nd trimester were masked, and the latent metal mixture increased the low-birth-weight risk in 2nd trimester by 2 % (OR = 1.02, 95 % CI = [1.00, 1.03]).</div></div><div><h3>Conclusion</h3><div>This study reveals time-dependent associations between a metal mixture in PM<sub>2.5</sub> exposure and adverse pregnancy outcomes, highlights the need to address dust in PM<sub>2.5</sub>, and provides additional evidence for understanding the pathway of the pollution effects on fetal health.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"12 ","pages":"Article 100113"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolism disruption induced by high ambient temperature 高环境温度引起的新陈代谢紊乱
Hygiene and environmental health advances Pub Date : 2024-09-28 DOI: 10.1016/j.heha.2024.100111
Ke Zhang , Gongbo Chen , Wan Liu , Jie He , Mengnan Pan , Zhongyang Chen , Jiahui Tong , Feifei Liu , Hao Xiang
{"title":"Metabolism disruption induced by high ambient temperature","authors":"Ke Zhang ,&nbsp;Gongbo Chen ,&nbsp;Wan Liu ,&nbsp;Jie He ,&nbsp;Mengnan Pan ,&nbsp;Zhongyang Chen ,&nbsp;Jiahui Tong ,&nbsp;Feifei Liu ,&nbsp;Hao Xiang","doi":"10.1016/j.heha.2024.100111","DOIUrl":"10.1016/j.heha.2024.100111","url":null,"abstract":"<div><h3>Background</h3><div>Previous studies have assessed the cardiovascular risk attributable to high ambient temperature. However, the mechanisms underly acute cardiovascular responses associated with high ambient temperature remain incompletely understood.</div></div><div><h3>Objective</h3><div>To identify acute cardiovascular responses associated with high temperature, and to understand the underlying mechanisms using metabolomics.</div></div><div><h3>Methods</h3><div>We conducted a prospective panel study on young adults, organizing participants to undergo blood collection and temperature monitoring tautologically. Levels of 10 cardiovascular biomarkers and 4473 serum metabolites were measured. Levels of ambient temperature exposure were recorded by wearing personal monitors. We employed linear mixed-effect models to identify acute cardiovascular responses associated with ambient temperature, including differential biomarkers and metabolites. KEGG pathway analysis was performed on the differential metabolites to identify temperature-associated metabolic processes.</div></div><div><h3>Results</h3><div>Exposure to elevated ambient temperature was associated with acute cardiovascular responses, including alterations in high-density lipoprotein, interleukin-6, C-reactive protein, diastolic pressure, and heart rate. These observed acute cardiovascular responses are probably attributed to metabolism disturbances, as 129 differential serum metabolites, accompanied by disruptions in 18 pathways, were identified. These differential metabolites and pathways primarily involve glycerophospholipid metabolism, which activates inflammation cytokines and subsequently induces adverse cardiovascular effects.</div></div><div><h3>Conclusions</h3><div>Our findings suggest that elevated ambient temperature could potentially lead to cardiovascular responses among young adults in China. We propose that high ambient temperature exposure may contribute to acute cardiovascular effects by regulating the glycerophospholipid metabolism pathway.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"12 ","pages":"Article 100111"},"PeriodicalIF":0.0,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142444971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive and negative impacts of COVID-19 on the environment: A critical review with sustainability approaches COVID-19 对环境的积极和消极影响:采用可持续发展方法进行严格审查
Hygiene and environmental health advances Pub Date : 2024-09-11 DOI: 10.1016/j.heha.2024.100107
Avishek Talukdar , Sayan Bhattacharya , Saptarshi Pal , Pracheta Pal , Soumyajit Chowdhury
{"title":"Positive and negative impacts of COVID-19 on the environment: A critical review with sustainability approaches","authors":"Avishek Talukdar ,&nbsp;Sayan Bhattacharya ,&nbsp;Saptarshi Pal ,&nbsp;Pracheta Pal ,&nbsp;Soumyajit Chowdhury","doi":"10.1016/j.heha.2024.100107","DOIUrl":"10.1016/j.heha.2024.100107","url":null,"abstract":"<div><div>Coronavirus, which practically brought the world to a standstill, is a member of the Coronaviridae family of the order Nidovirales, and was termed as the \"severe acute respiratory syndrome coronavirus 2″ (SARS-CoV-2) by the International Committee on Taxonomy of Viruses. The COVID-19 pandemic was probably the most critical healthcare and scientific challenge of this century. Apart from health concerns, the pandemic has also resulted in certain long-lasting social, economic, and environmental issues. The article, for the first time, executes a multidisciplinary assessment of the effects of COVID-19 on the environment, highlighting future research approaches and the possible ways to achieve sustainability in the post-COVID era. Both positive and negative impacts of COVID-19 pandemic are discussed in this context. While there are certain positive impacts of COVID-19 on the environment (including reduced air, water and noise pollution with cleaner landscapes), the negative impacts (increased production and consumption of plastics, increase in waste generation because of online consumption, decrease in waste recycling, energy consumption in vaccine manufacturing) pose considerable threats to the environment. We highlight urgent research priorities, and also discuss potential means of tackling any such pandemic in the future without hampering sustainable lifestyle or jeopardizing the environment and ecosystem dynamics. The findings will help to identify the possible areas of concern of pandemic management and can help in formulation of policies which will be helpful to reduce the impact of future pandemics on the environment.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"12 ","pages":"Article 100107"},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000205/pdfft?md5=09f664e89679e1f8e4613f3697d38a36&pid=1-s2.0-S2773049224000205-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142314471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupational chemical safety and management: A case study to identify best practices for sustainable advancement of Bangladesh 职业化学品安全与管理:确定孟加拉国可持续发展最佳做法的案例研究
Hygiene and environmental health advances Pub Date : 2024-09-10 DOI: 10.1016/j.heha.2024.100110
Amit Hasan Anik , Mohammad Toha , Shafi M Tareq
{"title":"Occupational chemical safety and management: A case study to identify best practices for sustainable advancement of Bangladesh","authors":"Amit Hasan Anik ,&nbsp;Mohammad Toha ,&nbsp;Shafi M Tareq","doi":"10.1016/j.heha.2024.100110","DOIUrl":"10.1016/j.heha.2024.100110","url":null,"abstract":"<div><p>Bangladesh has experienced numerous tragedies and casualties in the chemical industry, resulting in unparalleled losses in terms of human, social, and economic adversity, primarily attributed to the absence of effective occupational health and safety management. Despite having various sectoral legislative frameworks, there is a notable absence of a comprehensive legal framework specifically addressing chemical safety management issues. Moreover, the existing regulations have not successfully established a nexus between chemical safety, employee well-being, potential opportunities, and task performance. This highlights the insufficient attention given to occupational health and chemical safety issues at the policy level, with limited research dedicated to these critical concerns. Consequently, this critical review aims to identify optimal strategies for the long-term sustainable development of Bangladesh in the realm of occupational chemical safety and management. The review critically evaluates the current state of Bangladesh's national chemical management, offering a policy trajectory for consideration. It meticulously analyzes the disjunctions and incongruities between prescribed guidelines and actual practices in chemical management within the Bangladeshi context. Furthermore, it establishes a comprehensive framework for a nationwide chemical management system, aligning with global best practices and guidelines. The study also delineates existing gaps and challenges while outlining future priorities that warrant immediate government attention and sustained commitment to enhance chemical safety management. Therefore, this study serves as a foundational reference for policymakers not only in Bangladesh but also for those in other developing economies grappling with escalating chemical demands, providing guidance for constructing an appropriate infrastructure and legal framework for enduring chemical management.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"12 ","pages":"Article 100110"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000230/pdfft?md5=c11a758857e7fdba9fa43884960952d5&pid=1-s2.0-S2773049224000230-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142240646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Black box analysis with linear regression on global warming 关于全球变暖的线性回归黑箱分析
Hygiene and environmental health advances Pub Date : 2024-09-03 DOI: 10.1016/j.heha.2024.100109
Yoshiyasu Takefuji
{"title":"Black box analysis with linear regression on global warming","authors":"Yoshiyasu Takefuji","doi":"10.1016/j.heha.2024.100109","DOIUrl":"10.1016/j.heha.2024.100109","url":null,"abstract":"<div><p>This paper demonstrates that the conclusions drawn from datasets on global temperature anomaly and atmospheric CO2 from NOAA can vary depending on the range of investigated periods. By examining the data from both macroscopic and microscopic perspectives, the study reveals that different levels of analysis can produce different outcomes from the same datasets based on statistics.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"12 ","pages":"Article 100109"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000229/pdfft?md5=8dea976b9745ec91f3c29a1401fbba02&pid=1-s2.0-S2773049224000229-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142149605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expansion of a versatile pathogen: Clostridioides difficile 一种多用途病原体的扩展:艰难梭菌
Hygiene and environmental health advances Pub Date : 2024-09-03 DOI: 10.1016/j.heha.2024.100108
Tereena Lucas , Brent Brown
{"title":"Expansion of a versatile pathogen: Clostridioides difficile","authors":"Tereena Lucas ,&nbsp;Brent Brown","doi":"10.1016/j.heha.2024.100108","DOIUrl":"10.1016/j.heha.2024.100108","url":null,"abstract":"<div><p><em>Clostridioides difficile</em> is a gram positive and spore forming bacterium responsible for significant global morbidity and mortality. There is increasing incidence of <em>C. difficile</em> disease that constitutes a deviation from the traditionally understood toxin-mediated colonic disease. Comprehensive literature review has determined a conservative increase of over 600 cases of <em>C. difficile</em> extra–intestinal and small–intestinal disease detailed in &gt;200 papers over the past 20 years. Chronic colonization with increased intestinal permeability that permits the translocation of toxins and metabolites may partially explain this expanded disease manifestation. Currently there is little evidence in support of a role for toxins however, and greater evidence to support the role of metabolites in extra-intestinal disease pathogenesis. Specifically, increased levels of p-cresol, p-cresyl sulfate, indoxyl sulfate and ammonia are associated with <em>C. difficile</em>colonization. One important health consideration involves ongoing biotransformation of such metabolites, together with the overall metabolic load from all endogenous and exogenous sources, that can result in glutathione depletion. Chronic glutathione depletion in turn increases oxidative stress and is correlated with neurological compromise across all age groups, and a host of other conditions. Key factors supporting chronic colonization with <em>C. difficile</em> in susceptible hosts include widespread and indiscriminate use of antimicrobials, pharmaceuticals, pesticides, intensive agricultural practices, diet, food additives, and gastrointestinal disturbances. Appreciation of the role of the exposome in <em>C. difficile</em> disease expansion will further emphasize the importance of decreasing environmental contamination, antimicrobial resistance, inter-species transmission, and individual toxic metabolite burdens.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"12 ","pages":"Article 100108"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000217/pdfft?md5=b73b3f0a28575f48f0f30efede611fe6&pid=1-s2.0-S2773049224000217-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142149609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Removal mechanism of decabromodiphenyl ether in soil by Cu/Fe nanoparticles 铜/铁纳米颗粒去除土壤中十溴二苯醚的机理
Hygiene and environmental health advances Pub Date : 2024-09-03 DOI: 10.1016/j.heha.2024.100106
Siyuan Ling , Ying Han , Shuangqing Hu
{"title":"Removal mechanism of decabromodiphenyl ether in soil by Cu/Fe nanoparticles","authors":"Siyuan Ling ,&nbsp;Ying Han ,&nbsp;Shuangqing Hu","doi":"10.1016/j.heha.2024.100106","DOIUrl":"10.1016/j.heha.2024.100106","url":null,"abstract":"<div><p>Decabromodiphenyl ether (BDE-209), a widely used and environmentally significant legacy brominated flame retardant, is frequently found in farmland soil near electronic waste disposal sites and manufacturing facilities. Due to their high adsorption and dehalogenation capabilities, nanoparticles have become a prominent solution for soil remediation. Herein, Cu/Fe bimetallic nanoparticles (BNPs) were prepared and the use of these particles was investigated for the removal of BDE-209 from soil. Optimal conditions, including 9.1 wt% Cu loading and acidic environments, were identified to enhance the removal efficiency. The process involves desorption from soil, adsorption onto BNPs, and subsequent degradation. The contributions of adsorption and degradation were investigated by isolating the BNPs after the experiments conducted herein. Initially, adsorption played an important role, accounting for 25 %–38 % of the total removal, but this decreased to 14 % to 20 % as the reaction progressed, reaching at the equilibrium adsorption capacity after ∼3 h. Notably, hydroxylated polybrominated diphenyl ethers (PBDE) congeners were absent in all soil, BNP, and aqueous solution samples, indicating that stepwise debromination primarily drives the degradation process.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"12 ","pages":"Article 100106"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000199/pdfft?md5=34a95efe77d5a8b0d0b57cc93713e90c&pid=1-s2.0-S2773049224000199-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142149606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From human cohorts to plant cohorts: The potential of plants in epidemiological studies 从人类队列到植物队列:植物在流行病学研究中的潜力
Hygiene and environmental health advances Pub Date : 2024-09-02 DOI: 10.1016/j.heha.2024.100105
Tianyu Zhao , Joachim Heinrich
{"title":"From human cohorts to plant cohorts: The potential of plants in epidemiological studies","authors":"Tianyu Zhao ,&nbsp;Joachim Heinrich","doi":"10.1016/j.heha.2024.100105","DOIUrl":"10.1016/j.heha.2024.100105","url":null,"abstract":"<div><p>Cohort studies are traditionally focused on human participants. The emergence of the “Planetary Health” and “One Health” paradigms has expanded the scope of cohort studies to include animal participants. Despite this, plants remain largely overlooked in traditional biomedical research. This gap prompts the introduction of the concept of a “plant cohort,” which involves treating plants as participants in cohort studies. By collecting comprehensive data on plant characteristics and biosamples, plant cohorts may assist in enhancing our understanding of the interactions between plants, ecosystems, and human health. However, establishing plant cohorts presents unique challenges, including interdisciplinary collaboration and data collection methods. Nonetheless, the potential contribution of plant cohorts to environmental health and human well-being may warrant further exploration and research.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"12 ","pages":"Article 100105"},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000187/pdfft?md5=a712573f282290ee7a4ca8ec8a17c2e4&pid=1-s2.0-S2773049224000187-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142162254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mobile air-decontamination units: Can they be used for immunocompromised patients at high risk for fungal infections? 移动式空气净化装置:能否用于真菌感染高风险免疫力低下的病人?
Hygiene and environmental health advances Pub Date : 2024-07-26 DOI: 10.1016/j.heha.2024.100102
Joris Voisin , Jacqueline Shum Cheong Sing , Claire Terreaux-Masson , Carola Pierobon , Anne Thiebaut-Bertrand , Hervé Pelloux , Caroline Landelle , Marie-Pierre Brenier-Pinchart
{"title":"Mobile air-decontamination units: Can they be used for immunocompromised patients at high risk for fungal infections?","authors":"Joris Voisin ,&nbsp;Jacqueline Shum Cheong Sing ,&nbsp;Claire Terreaux-Masson ,&nbsp;Carola Pierobon ,&nbsp;Anne Thiebaut-Bertrand ,&nbsp;Hervé Pelloux ,&nbsp;Caroline Landelle ,&nbsp;Marie-Pierre Brenier-Pinchart","doi":"10.1016/j.heha.2024.100102","DOIUrl":"10.1016/j.heha.2024.100102","url":null,"abstract":"<div><p>Immunocompromised patients in the hematology department are usually hospitalized in areas protected by the high-efficiency particulate air (HEPA) filtration system. Renovations may require moving these patients at risk for invasive fungal infection to areas without HEPA. Mobile air handling units may be a solution in these cases. For renovation purposes, we evaluated the efficiency of mobile air handling units called Plasmair® as well as their optimization, by comparing two generations of devices.</p><p>Particle counts were performed to determine a particle cleanliness classification according to the ISO 14644–1 standard (high ISO classes correspond to a degraded particulate cleanliness). Mycological air samples were also taken to determine the percentage of positive samples and the median number of filamentous fungi colonies.</p><p>Without air treatment, only 18 % (38/216) of particle counts were classified as ISO 6. With the use of mobile air treatment units, this proportion increased to 71 % (205/288). The positivity rate of mycological samples without air treatment was 86 % (31/36) with a median number of fungal colonies of 3 (1–5)/0.5m<sup>3</sup>. A significant decrease in fungal pressure was observed when using Plasmair®. Percentages of positive air samples and the median number of colonies found between the old generation Plasmair® (T2006) and the new generation Plasmair® (Guardian) were significantly different, respectively 55.6 % (20/36) <em>versus</em> 22.2 % (8/36) and 1(0–1) <em>versus</em> 0 (0–0).</p><p>Finally, we confirm Plasmair® were effective in reducing airborne fungal pressure, the new generation especially. However, they were not effective enough to obtain negative mycological air samples as usually observed with the HEPA system, whatever the generation.</p></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"11 ","pages":"Article 100102"},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773049224000151/pdfft?md5=88679416b1a922398b45cfc4f2f29bed&pid=1-s2.0-S2773049224000151-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141851411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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