Hygiene and environmental health advances最新文献

{"title":"Adolescent bone health under threat: PFAS mixtures as drivers of skeletal fragility","authors":"Jing Li ,&nbsp;Shaowei Wu ,&nbsp;Tingyu Li ,&nbsp;Zichang Liu ,&nbsp;Chuchu Kang ,&nbsp;Hongli Tan","doi":"10.1016/j.heha.2025.100133","DOIUrl":"10.1016/j.heha.2025.100133","url":null,"abstract":"<div><div>Evidence regarding the effect of per- and poly-fluoroalkyl substances (PFASs) on bone minerals density (BMD) at various bone sites and the combined effects of PFAS mixtures is limited, particularly during the critical period of skeletal development. To address this gap, we conducted a cross-sectional study involving 1212 adolescents aged 12−19 years in NHANES 2011−2018 to examine the associations of single PFAS and PFAS mixtures with BMD at 11 bone sites and two comprehensive BMD indices. Multiple linear regression showed that serum PFAS concentrations were inversely associated with BMD, with variations according to the specific PFAS and bone site, and exhibiting a sex-specific pattern. Additionally, these associations differed significantly between obese and non-obese individuals, which was confined to boys. Mixture analysis using weighted quantile sum regression and Bayesian kernel machine regression revealed inverse associations between PFAS mixtures and BMD at specific bone sites, and 2-(N-methylperfluoroctanesulfonamido)acetic acid (Me-PFOSA-AcOH) and perfluorodecanoic acid (PFDeA) were identified as the dominant contributors to the combined effect of PFAS mixtures on BMD among all participants and girls, respectively. These findings lay a critical foundation for future environmental epidemiology studies and necessitate further exploration and validation of mechanisms through laboratory research.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"15 ","pages":"Article 100133"},"PeriodicalIF":0.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The dose-dependent effect of acute ozone exposure on lung function and the efficacy of a Boysenberry apple powder blend (BerriQi®) in reducing throat irritation and symptom recovery time in healthy adults","authors":"Dominic Lomiwes ,&nbsp;Matthew Barnes ,&nbsp;Grayson Nicholls ,&nbsp;Nayer Ngametua ,&nbsp;Greg Sawyer ,&nbsp;Alexander P. Kanon ,&nbsp;Gowthami Vangala ,&nbsp;Odette Shaw","doi":"10.1016/j.heha.2025.100132","DOIUrl":"10.1016/j.heha.2025.100132","url":null,"abstract":"<div><div>Urbanization and industrialization have impacted air quality and health, with ozone exposure linked to reduced lung function and increased respiratory issues. This study characterised the dose-dependent effect of acute, controlled ambient ozone exposure in an environmental chamber on lung function, then investigated the effect of BerriQi® Boysenberry and apple powder (BerriQi) ozone-induced respiratory irritation symptoms. In an incremental dose study, healthy adults were exposed to 0.1, 0.2 or 0.3 ppm ozone for 2 h. Forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1) were measured at designated timepoints up to 48 h after ozone exposure. This was followed by a randomised, double-blind, placebo-controlled crossover trial, with healthy adults (<em>n</em> = 20) who consumed either BerriQi or a placebo daily for 5 days before being exposed to 0.2 ppm ozone for 2 h. Respiratory irritation symptoms, including throat irritation (TI), soreness of cough (SOC), shortness of breath (SOB), and pain on deep inspiration (PODI), were assessed at designated timepoints up to 48 h after ozone exposure. Our results showed that 0.2 ppm ozone was the maximum tolerated dose that elicited a temporal decline in lung function in healthy participants and that BerriQi supplementation significantly reduced TI (<em>p</em> = 0.04), and may expedite the resolution of SOC, SOB and PODI after acute ozone exposure. These findings suggest that BerriQi may alleviate the severity and duration of ozone-induced respiratory irritation and highlights the potential of BerriQi as a dietary intervention for mitigating the respiratory effects of air pollution.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"15 ","pages":"Article 100132"},"PeriodicalIF":0.0,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144272213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of childhood per- and polyfluoroalkyl substances with autistic traits and symptom severities among children with and without autism spectrum disorder","authors":"Li-Zi Lin ,&nbsp;Nanxiang Jin ,&nbsp;Wan-Ting He ,&nbsp;Yun-Ting Zhang ,&nbsp;Jing-Wen Huang ,&nbsp;Li-Xia Liang ,&nbsp;Jia-Xin Zhou ,&nbsp;Zhe-Qing Zhang ,&nbsp;Xin Wang ,&nbsp;Zhao-Huan Gui ,&nbsp;Ru-Qing Liu ,&nbsp;Jing-Jing Liang ,&nbsp;Guang-Hui Dong","doi":"10.1016/j.heha.2025.100131","DOIUrl":"10.1016/j.heha.2025.100131","url":null,"abstract":"<div><div>The associations of childhood legacy and alternatives per- and polyfluoroalkyl substances (PFASs) with autism spectrum disorder (ASD) -related outcomes were seldom discussed. In this case-control study conducted in Guangzhou, China, 6- to 9-year-old children who were clinically confirmed for ASD (case, n = 60) or typical development (TD, n = 180) underwent psychometric tests (autistic traits via Autism Spectrum Quotient-Children and symptom severities via Social Responsiveness Scale), and we tested their plasma concentrations of 16 legacy and alternative PFASs. We used conditional logistic regression models and generalized linear models to test the associations of PFASs exposure with ASD-related outcomes. Higher concentrations of total and linear PFHxS were associated with higher risk of ASD [OR = 2.44, 95% confidence interval (CI): 1.05-5.67; 2.73, 95%CI: 1.17-6.38] and higher autistic traits among TD children (β = 0.45, 95%CI: 0.03-0.87; 0.44, 95%CI: 0.01- 0.86). In addition, we observed a positive association between symptom severity and 8:2 Cl-PFESA, an alternative PFAS compound, among children with ASD (β =4.90, 95%CI: 0.07-9.72). We did not find joint associations between PFASs mixtures and the outcomes when using multiple-pollutant models. More studies are needed to confirm the PFASs-ASD associations, and the potential hazards of emerging PFASs should not be ignored.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"15 ","pages":"Article 100131"},"PeriodicalIF":0.0,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144263934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanistic insights into cobalt-induced lung injury: An integrated network toxicology and bioinformatics approach","authors":"Hongyan Yu ,&nbsp;Yingzhu Wang ,&nbsp;Yidi Chen ,&nbsp;Rong Zhang ,&nbsp;Shanfa Yu ,&nbsp;Xiaoting Jin ,&nbsp;Yuxin Zheng","doi":"10.1016/j.heha.2025.100130","DOIUrl":"10.1016/j.heha.2025.100130","url":null,"abstract":"<div><h3>Background</h3><div>The widespread environmental contamination by cobalt compounds, coupled with their documented respiratory toxicities, has become a pressing public health concern. Current mechanistic research on the health impacts of these substances lacks coherence and integration, highlighting the need for a comprehensive investigation into the mechanisms of cobalt-induced lung injury.</div></div><div><h3>Methods</h3><div>Utilizing CTDbase and NetInfer databases, we obtained target genes of cobalt and its compound and ascertained their associated lung adverse outcomes. Disease-related targets were retrieved from OMIM, DisGeNet, GeneCards, and NCBI databases. A protein-protein interaction (PPI) network was constructed to identify the core targets between compounds and diseases. Based on the DAVID database, enrichment pathways were evaluated by GO and KEGG analyses. Finally, single-cell analysis was conducted to investigate specific cell types implicated in the cobalt-induced lung hazards.</div></div><div><h3>Results</h3><div>Pulmonary hypertension (PH) was determined as the most critical lung injury associated with cobalt compounds. In total, we identified 275 compound-related and 3146 PH-related targets, ultimately pinpointing 169 overlapping targets. Among these, 28 pivotal co-targets were implicated in cobalt and its compound-induced PH, including IL6, AKT1, TNF, TP53, NFKB1, HIF1A, etc., which were primarily involved in the IL-17, TNF, and HIF-1 signaling pathways. Moreover, monocytes and macrophages were recognized as effector cells underlying the induction of PH by cobalt exposure, with CXCL8 and HIF1A serving as signature genes.</div></div><div><h3>Conclusion</h3><div>Our study not only elucidates pivotal target genes, pathways, and specific cell types involved in cobalt-induced lung hazards, but also establishes a novel approach to clarify the mechanisms underlying metal toxicity.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"15 ","pages":"Article 100130"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144272212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of heavy metals pollution in vegetables grown on irrigated soil and their potential threat to human health and global food security","authors":"Bahati J. Manegabe ,&nbsp;Titus A.M. Msagati ,&nbsp;Adeeyo Adeyemi Ojutalayo ,&nbsp;Marie-Médiatrice Kikongo Ntabugi ,&nbsp;John B. Dewar ,&nbsp;Karin De Bryun","doi":"10.1016/j.heha.2025.100129","DOIUrl":"10.1016/j.heha.2025.100129","url":null,"abstract":"<div><div>Heavy metals accumulation in vegetables grown on irrigated soils are affected by human-and natural activities. They represent a serious global concern due to the presence of harmful elements in the water used for irrigation that later accumulate in the soil at high level, affecting soil quality, crops and human health. Within the rhizosphere, metals severely affect microbiome and vegetables physiological function, which can compromise vegetable qualities and through their accumulation present a serious threat to consumers. Factors that influence heavy metal availability include the pH, organic matter, crop- and microbial deposits. Plant and associated symbiotic bacteria have evolved strategies to mitigate metal bacterial secretion into rhizosphere, including the siderophores, phytohormones, antibiotics, mucilage, organic acids, phenols, polypeptides, exopolysaccharides (EPS), as well as inorganic ligands such as NH₄⁺, PO₄^3-, and more may chelate heavy metal ions, desirable to decrease the availability and the uptake of heavy metals in plant and bacteria, potentially beneficial to plants and humans. This review focuses on the source of heavy metals in irrigated soils where vegetables are grown, mobility/availability of metals in such soil, uptake/accumulation by the plant, toxicity of these heavy metals to vegetables and human, and the mitigation strategies used by plants and bacteria to reduce the impact of metals on humans via the food chain.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"14 ","pages":"Article 100129"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144241833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomonitoring result of PFAS exposure from Gabreski Air National Firefighting foam among residents in Westhampton, NY","authors":"Yichun Liu ,&nbsp;Eric J. Rose ,&nbsp;Karen Wilson ,&nbsp;Wanhsiang Hsu ,&nbsp;Ming Liu ,&nbsp;Monica Nordstrom ,&nbsp;Elizabeth J. Mullin ,&nbsp;Steven P. Forand","doi":"10.1016/j.heha.2025.100127","DOIUrl":"10.1016/j.heha.2025.100127","url":null,"abstract":"<div><h3>Background</h3><div>Perfluorooctanoic sulfonic acid (PFOS) and other per- and poly-fluoroalkyl substances (PFAS) are considered emerging contaminants. The New York State Department of Health (NYSDOH) conducted a PFAS biomonitoring program for a sample of the population served by the public water supply in the Westhampton, NY area (<em>n</em> = 161). The objective of this study was to assess PFAS exposure levels in the study area and identify potential risk factors associated with PFAS concentrations.</div></div><div><h3>Methods</h3><div>Descriptive analyses were conducted to present both demographic and exposure characteristics. Mann-Whitney U Tests were conducted to compare the differences of four PFAS concentrations, PFOS, PFOA, PFHxS and PFNA, respectively, between the study group and the general population age 12 years and above (NHANES 2017–2018). Multiple linear regressions were conducted to examine PFAS concentration levels in relation to demographic and exposure characteristics. A sub-analysis was conducted for the female only study group to examine the associations between PFAS, risk factors and reproductive factors.</div></div><div><h3>Results</h3><div>The concentrations of PFAS levels in the Westhampton study group were in general higher than the 2017–2018 U.S population. A positive association was found between age, sex, length of residency (LOR) in the study area and local fish consumption and PFAS serum levels. The final model for PFOS concentrations among females in this study shows that the number of pregnancies was inversely associated with PFOS serum levels. These findings are consistent with other biomonitoring studies.</div></div><div><h3>Conclusion</h3><div>The PFAS serum levels among study population were slightly elevated compared to the general U.S. population, suggesting a possible relation to public drinking water exposure but not indicative of long-term, high-level exposure to PFAS in the area. For a more thorough biomonitoring surveillance, systematic monitoring with more comprehensive questionnaire should be developed for emerging contaminants such as PFAS.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"14 ","pages":"Article 100127"},"PeriodicalIF":0.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144070079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of risks associated with environmental change on refractive and non-refractive ocular health: Special focus on Africa","authors":"Emmanuel Elochukwu Okenwa-Vincent ,&nbsp;Nathan Riel ,&nbsp;Linda S. Pagani","doi":"10.1016/j.heha.2025.100128","DOIUrl":"10.1016/j.heha.2025.100128","url":null,"abstract":"<div><h3>Background</h3><div>Over the past two decades, the African continent has faced numerous environmental shifts that affect population health. Climate change, rapid urbanization, and air pollution contribute significant risks to human health. The impact of these shifts on refractive and non-refractive ocular health in Africa remains largely empirically undocumented.</div></div><div><h3>Objectives</h3><div>A systematic review of the risks associated with environmental factors on refractive and non-refractive ocular health, with a specific emphasis on the African context.</div></div><div><h3>Methods</h3><div>This systematic review over the recent decade, conforming to PRISMA guidelines, spanned two primary databases, PubMed, and Google Scholar. It included a combination of keywords related to ocular health, environmental change, air pollution, climate change, water quality, and other related concepts. In total, it captured 77 articles from 2013 to July 2023 that met review quality guidelines.</div></div><div><h3>Results</h3><div>The review comprised varied study designs with a notable inclusion of cross-sectional (25·9%), cohort (14·3%), and review articles (36·4%). Findings indicated a significant correlation between air pollutants like PM_2·5 and NO_x with ocular diseases such as dry eye and ocular surface disorders (16·8%), conjunctival disorders (7·8%), and myopia (5·2%). Climate change exacerbated by rising temperatures and UV radiation was implicated in 39% of studies, with a specific focus on its relation to cataracts (5·2%) and retinal-related disorders (10·4%). Additionally, indoor air pollution disproportionately affected women and children in rural settings of Africa.</div></div><div><h3>Conclusions</h3><div>The data indicate the need for urgent continental and regional policies against air pollution and climate change to safeguard ocular health, especially among vulnerable African populations. The review underscores the need for interdisciplinary policy to address challenges. The documentation of the relationship between environmental factors and ocular health intersects with Sustainable Development Goals that emphasize the need for improved preventive eye care and intervention, particularly among vulnerable populations and rural inhabitants.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"14 ","pages":"Article 100128"},"PeriodicalIF":0.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144070080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urban green spaces and mental health: Findings from Uganda","authors":"Hilbert Mendoza ,&nbsp;Solomon T. Wafula ,&nbsp;Katrien De Troeyer ,&nbsp;Hayat Bentouhami ,&nbsp;Busisiwe Shezi ,&nbsp;Grace Biyinzika Lubega ,&nbsp;Rawlance Ndejjo ,&nbsp;John Bosco Isunju ,&nbsp;Richard Mugambe ,&nbsp;David Musoke ,&nbsp;Lidia Casas","doi":"10.1016/j.heha.2025.100126","DOIUrl":"10.1016/j.heha.2025.100126","url":null,"abstract":"<div><h3>Background</h3><div>Urban green spaces (UGS) may improve mental health in high-income countries. However, evidence from low-income African countries is scarce. Here, we assessed the associations of UGS with depressive and anxiety symptoms among adult residents of Kampala District (Uganda), the potential effect modification by sociodemographic factors, and the mediation roles of social interaction, outdoor physical activity, and residential distance to major roads as a proxy of traffic-related air pollution.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional survey among 641 adults. We objectively measured UGS using the Normalized Difference Vegetation Index (NDVI) within buffers of 100 m and 1,000 m around the residences. We assessed the utilization of UGS as a self-reported frequency (never, occasionally, and frequently) by which individuals visited UGS in the past 6 months. The Patient Health Questionnaire-9 and the Generalized Anxiety Disorder 7-item scale were used to examine the severity of depressive and anxiety symptoms respectively. We used modified Poisson regression models to obtain prevalence ratios (PR) with their 95 % confidence intervals (CI), stratified our models, and conducted mediation analyses.</div></div><div><h3>Results</h3><div>We observed an inverse association between UGS and both outcomes. For example, an inter-quartile range increase in UGS within a 100 m buffer was associated with a 6 % and 8 % decrease in depressive and anxiety symptoms, respectively (PR=0.94; 95 % CI=0.89–0.99, and PR=0.92; 95 % CI=0.85–0.95, respectively). Consistently, frequent visits to UGS relative to no visits were associated with a 33 % and 35 % lower prevalence of depressive and anxiety symptoms (PR=0.67; 95 %CI=0.53–0.84, and PR=0.65; 95 %CI=0.47–0.91, respectively). Depending on the UGS metric, we observed varying potential effect modification findings by sex, age, and educational level. Finally, residential distance to major roads emerged as a mediator in the association between residential surrounding greenness and depressive symptoms.</div></div><div><h3>Conclusion</h3><div>Our study suggests that UGS may also improve the mental health among residents of rapidly urbanizing African low-income cities.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"14 ","pages":"Article 100126"},"PeriodicalIF":0.0,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143921913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing health risk reduction from road traffic noise: The impact of vehicle composition and traffic speed in the transition to electric vehicles – A prediction in Sapporo City, Japan","authors":"Farah Elida Selamat ,&nbsp;Junta Tagusari","doi":"10.1016/j.heha.2025.100125","DOIUrl":"10.1016/j.heha.2025.100125","url":null,"abstract":"<div><div>Environmental noise poses a risk to public health. Recent societal shifts aimed at creating a low-carbon society are expected to change the acoustic landscape, such as the transition from internal combustion engine vehicles (ICEVs) to electric vehicles (EVs). However, the impact of transitioning to EVs on traffic conditions and health risk reduction remains uncertain. This study aims to evaluate traffic efficiency and clarify how shifting from ICEVs to EVs influences health risks associated with road traffic noise. We analysed the relationship between health risk reduction, vehicle composition (i.e., proportion/percentage of heavy vehicles), and traffic speed according to the CNOSSOS-EU noise emission model and the exposure-response functions provided in the Environmental Noise Guidelines by the World Health Organization Regional Office for Europe (WHO-EU). The results were validated by estimating the reduction of health risks in small and large urban areas using actual traffic conditions. The results of the calculations indicate that a greater percentage of heavy EVs and lower traffic speeds lead to a more significant reduction in health risks. In the two selected areas, the region with a higher proportion of heavy EVs achieved a risk reduction of 30–40 %, whereas the area with a lower percentage of heavy EVs experienced approximately a 20 % reduction. The reduction of each health risk in both areas was consistent with the calculation results. In Sapporo City, the health risk reduction was estimated to be 15—20 %. This study demonstrated that transitioning to EVs effectively reduces health risks associated with road traffic noise and identifies the optimal traffic conditions for minimizing these risks. Increasing the adoption of EVs could serve as a significant strategy for alleviating the health impacts of road traffic noise.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"14 ","pages":"Article 100125"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143888136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between temperature variability, morbidity and mortality for specific categories of disease: A systematic review and meta-analysis","authors":"Maxwell D. Weidmann","doi":"10.1016/j.heha.2025.100123","DOIUrl":"10.1016/j.heha.2025.100123","url":null,"abstract":"<div><div>While research into temperature-related health outcomes has focused on absolute temperature exposure, an increasing number of studies have explored the distinct effect of temperature variability (TV). However, systematic reviews in this area have focused on a limited number of health outcomes and intra-day TV. A systematic review was therefore conducted for studies of intra- and/or inter-day TV and cardiovascular, respiratory, renal or mental illnesses through April 2023 (<em>n</em> = 38). There was a consistent relationship between cardiovascular disease (CVD) or respiratory disease (RD) morbidity, mortality and both diurnal temperature range (DTR) or short-term inter-day TV, particularly for the elderly. The effect of DTR and short-term inter-day TV were stronger on hot days and the warm season for CVD, but on cold days and cold season for RD. Meta-analysis for CVD or RD and DTR showed a significant 0.7 %/C° increase in CVD mortality, but not morbidity, while RD showed a significant 1.0 %/C° and 0.7 %/C° increase in morbidity and mortality, respectively. Most studies focused on CVD, RD, DTR or short-term inter-day TV, while few studies explored renal, GU, or mental health outcomes aside from schizophrenia. Future studies are needed to assess non-linear relationships between TV and disease, and the modifying effect of socioeconomic status.</div></div>","PeriodicalId":73269,"journal":{"name":"Hygiene and environmental health advances","volume":"14 ","pages":"Article 100123"},"PeriodicalIF":0.0,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143916754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}