Biomonitoring result of PFAS exposure from Gabreski Air National Firefighting foam among residents in Westhampton, NY

Yichun Liu , Eric J. Rose , Karen Wilson , Wanhsiang Hsu , Ming Liu , Monica Nordstrom , Elizabeth J. Mullin , Steven P. Forand
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Abstract

Background

Perfluorooctanoic sulfonic acid (PFOS) and other per- and poly-fluoroalkyl substances (PFAS) are considered emerging contaminants. The New York State Department of Health (NYSDOH) conducted a PFAS biomonitoring program for a sample of the population served by the public water supply in the Westhampton, NY area (n = 161). The objective of this study was to assess PFAS exposure levels in the study area and identify potential risk factors associated with PFAS concentrations.

Methods

Descriptive analyses were conducted to present both demographic and exposure characteristics. Mann-Whitney U Tests were conducted to compare the differences of four PFAS concentrations, PFOS, PFOA, PFHxS and PFNA, respectively, between the study group and the general population age 12 years and above (NHANES 2017–2018). Multiple linear regressions were conducted to examine PFAS concentration levels in relation to demographic and exposure characteristics. A sub-analysis was conducted for the female only study group to examine the associations between PFAS, risk factors and reproductive factors.

Results

The concentrations of PFAS levels in the Westhampton study group were in general higher than the 2017–2018 U.S population. A positive association was found between age, sex, length of residency (LOR) in the study area and local fish consumption and PFAS serum levels. The final model for PFOS concentrations among females in this study shows that the number of pregnancies was inversely associated with PFOS serum levels. These findings are consistent with other biomonitoring studies.

Conclusion

The PFAS serum levels among study population were slightly elevated compared to the general U.S. population, suggesting a possible relation to public drinking water exposure but not indicative of long-term, high-level exposure to PFAS in the area. For a more thorough biomonitoring surveillance, systematic monitoring with more comprehensive questionnaire should be developed for emerging contaminants such as PFAS.
纽约州西汉普顿居民中Gabreski Air国家消防泡沫中PFAS暴露的生物监测结果
背景:全氟辛烷磺酸(PFOS)和其他单氟烷基和多氟烷基物质(PFAS)被认为是新兴污染物。纽约州卫生部(NYSDOH)对纽约州西汉普顿地区公共供水服务的人口样本(n = 161)进行了PFAS生物监测计划。本研究的目的是评估研究区域的PFAS暴露水平,并确定与PFAS浓度相关的潜在危险因素。方法进行描述性分析,以显示人口统计学和暴露特征。通过Mann-Whitney U检验,比较研究组与12岁及以上普通人群中PFOS、PFOA、PFHxS和PFNA四种PFAS浓度的差异(NHANES 2017-2018)。采用多元线性回归来检验PFAS浓度水平与人口统计学和暴露特征的关系。对女性研究组进行了一项亚分析,以检查PFAS、危险因素和生殖因素之间的关系。结果西安普顿研究组的PFAS浓度水平总体高于2017-2018年美国人群。研究区域的年龄、性别、居住时间与当地鱼类消费量和PFAS血清水平呈正相关。本研究中女性全氟辛烷磺酸浓度的最终模型表明,怀孕次数与全氟辛烷磺酸血清水平呈负相关。这些发现与其他生物监测研究一致。结论研究人群的PFAS血清水平与美国一般人群相比略有升高,这可能与公共饮用水暴露有关,但并不表明该地区长期高水平暴露于PFAS。为了更彻底地进行生物监测,应该对PFAS等新出现的污染物进行更全面的系统监测和问卷调查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Hygiene and environmental health advances
Hygiene and environmental health advances Environmental Science (General)
CiteScore
1.10
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