Global pediatrics最新文献

{"title":"Turkish Neonatal Society position paper for stem cell therapy in neonates","authors":"Merih Cetinkaya ,&nbsp;Esin Koc ,&nbsp;Betul Acunas ,&nbsp;Mete Akisu ,&nbsp;Saadet Arsan ,&nbsp;Fuat Emre Canpolat ,&nbsp;Dilek Dilli ,&nbsp;Zeynep Ince ,&nbsp;Nilgun Koksal ,&nbsp;Abdullah Kumral ,&nbsp;Eren Ozek ,&nbsp;Hasan Ozkan ,&nbsp;Ayse Korkmaz Toygar ,&nbsp;Sule Yigit ,&nbsp;Aysegul Zenciroglu ,&nbsp;Mehmet Vural","doi":"10.1016/j.gpeds.2024.100239","DOIUrl":"10.1016/j.gpeds.2024.100239","url":null,"abstract":"<div><div>Stem cell (SC) therapy has been proposed as a promising therapeutic modality in neonatology, especially for prevention and/or treatment of several interactable diseases such as bronchopulmonary dysplasia, intraventricular hemorrhage, hypoxic-ischemic encephalopathy and others. However, there are several uncertainities in terms of indications, timing, dosage, and safety of SC therapy for routine clinical use in neonates. Herein, a group of Turkish Neonatal Society members evaluated the systematic reviews, meta-analyses, clinical and experimental studies and also case-reports in the literature about the usage of SC therapy in neonatal diseases.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100239"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness evaluation of neonatal emergency transport organization in Italy","authors":"Carlo Bellini ,&nbsp;Maurizio Gente ,&nbsp;Diego Minghetti ,&nbsp;Luca A. Ramenghi","doi":"10.1016/j.gpeds.2025.100243","DOIUrl":"10.1016/j.gpeds.2025.100243","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to evaluate the cost-effectiveness of the Italian Neonatal Emergency Transport Service (NETS), to analyse its current organisation and to identify potential financial benefits from improvements.</div></div><div><h3>Methods</h3><div>Using data from the 2023 national NETS survey conducted by the Italian Society of Neonatology, regional cost-effectiveness of operating the system were calculated. These were compared with ideal costs for on-call and dedicated NETS models, based on a previously established methodology.</div></div><div><h3>Results</h3><div>The total cost of operating NETS in Italy was €32,785,650. Of this, €24,964,050 was associated with services organised according to the on-call model, while €7,821,600 was associated with dedicated services. The cost per transport varied considerably between regions. The national median cost for on-call services was €7,386 (ranging from €1,809 to €76,209), while the national median cost for dedicated services was €2,421 (ranging from €2,073 to €2,770). The actual total cost could be reduced to the ideal cost of €15,304,308, with the ideal cost per individual transport being €2,450 for on-call services and €2,250 for dedicated services (compared to the current medians of €7,386 and €2,421, respectively).</div></div><div><h3>Conclusions</h3><div>The study concluded that the Italian NETS organisation is expensive and unsustainable due to limited financial resources, and requires a complete overhaul. The implementation of a more cost-effective 'hub-and-spoke' NETS network system could significantly improve financial sustainability. The findings suggest that improvements to the NETS organisation are needed not only in Italy, but potentially across Europe.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100243"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Right side Bochdalek's hernia with right herniated thoracic renal ectopia: A case report and review of literature","authors":"Osias Tilahun Merga,&nbsp;Nebiyou Simegnew Bayleyegn","doi":"10.1016/j.gpeds.2024.100238","DOIUrl":"10.1016/j.gpeds.2024.100238","url":null,"abstract":"<div><h3>Introduction and importance</h3><div>Congenital diaphragmatic hernia is an uncommon defect of the diaphragm that can cause the abdominal contents to herniate into the chest cavity, putting the newborn at risk for complications with the heart and lungs. The spectrum of congenital diaphragmatic hernia disease can include acute respiratory failure that manifests as neonatal death, as well as asymptomatic problems that are not detected during the neonatal era.</div></div><div><h3>Case presentation</h3><div>A 6 kilogram, 4-month-old baby had been breathing rapidly for two weeks. According to the mother, he has also had breastfeeding interruption, dry intermittent cough, and high-grade intermittent fever. Meanwhile, the patient was diagnosed with severe acute malnutrition, severe pneumonia, and a congenital diaphragmatic hernia complicated with Intrathoracic ectopic kidney. He was admitted to pediatric ward and managed with intravenous antibiotics, intranasal oxygen and Formula-75 for two weeks.</div></div><div><h3>Clinical discussion</h3><div>Congenital diaphragmatic hernia is a rare kind of congenital surgical problem. The diaphragm fails to close during embryonic development, leading to intrathoracic abdominal viscera herniation, as well as variable degrees of pulmonary hypoplasia, pulmonary hypertension, and heart failure at birth. Intrathoracic ectopic kidneys are exceptionally rare. They represent only &lt;5 % of renal ectopia. The prognosis for early presenters in high-income nations has improved because of advancements in newborn care; nevertheless, in Africa, the situation is still dire.</div></div><div><h3>Conclusion</h3><div>Congenital diaphragmatic hernias with Intrathoracic ectopic kidneys are exceptionally rare. Compared to congenital diaphragmatic hernias linked to other abnormalities or syndromes, isolated congenital diaphragmatic hernias have a higher survival rate.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100238"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of surgical treatment on neonatal management in extremely low birth weight infants: Single-center retrospective study","authors":"Seiichiro Inoue,&nbsp;Yuki Muta,&nbsp;Yuta Takeuchi,&nbsp;Kohei Kawaguchi,&nbsp;Akio Odaka","doi":"10.1016/j.gpeds.2024.100240","DOIUrl":"10.1016/j.gpeds.2024.100240","url":null,"abstract":"<div><h3>Background</h3><div>Few studies have examined the details of extremely low birth weight (ELBW) infants (i.e., infants with a birth weight &lt; 1000 g) on neonatal intensive care units (NICUs) who require surgical treatment. Therefore, we analyzed mortality, morbidity, and clinical variables in ELBW infants who received surgical treatments at our center from 2009 to 2022.</div></div><div><h3>Methods</h3><div>All ELBW infants were included who received surgical treatment at our NICU from January 2009 to December 2022. We compared data from infants treated in the early (2009–2015) and late (2016–2022) periods and investigated trends in mortality, morbidity, and clinical variables.</div></div><div><h3>Results</h3><div>A total of 678 ELBW infants were admitted and cared at our neonatal center and 56 ELBW infants were received surgical treatment. The number of patients who received surgical treatment increased in the late period (10.4 % (36/345)) compared to the early period (6.33 % (20/316)) (early vs late period: <em>p</em> = 0.0398). The indications for surgery were expanded in late period compared to early periods. In the late period, the survival rate was higher (63.5 vs 75.0 %: early vs late period). No statistical difference was observed between the early and late period in the duration of the NICU stay. However, the duration of NICU stay in died patients were shorter compared to the survived patients (median (lower -upper quartiles):196.5 (166.75–261.25 vs 75.0 (49.0–183.5): early vs late period). The total number of surgical treatments which each patient received were higher in survived cases (median (lower -upper quartiles): 2.0 (2.0–4.0) vs 1.0 (1.0–2.0): survived vs died cases: <em>p</em> = 0.013).</div></div><div><h3>Conclusions</h3><div>Recent advances in NICU care have expanded the indications for surgical treatment in ELBW infants. Survival rates appear to have improved. In more recent years, patients have increasingly undergone multi-step surgical treatment, which we consider to be a result of the improved the systemic status of infants in perioperative period.</div></div><div><h3>Level of evidence</h3><div>3</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100240"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Newborn birth weight and its associated risk factors in Somalia using Somalia health and demographic survey","authors":"Denekew Bitew Belay ,&nbsp;Nigussie Adam Birhan ,&nbsp;Mahad Ibrahim Ali ,&nbsp;Ding-Geng Chen","doi":"10.1016/j.gpeds.2024.100241","DOIUrl":"10.1016/j.gpeds.2024.100241","url":null,"abstract":"<div><h3>Background</h3><div>Low birth weight is the result of fetal growth and it is a strong sign of infant morbidity and mortality. In sub-Saharan Africa, the number of low birth weight live births is estimated to have increased from 4.4 million in 2000 to 5 million in 2015. Low birth weight is a strong indicator of multifaceted public health problems, including unfavorable socio-demographic conditions, chronic illness, and poor health care during pregnancy. The aim of this study was to assess the prevalence and risk factors of newborn birth weight in Somalia.</div></div><div><h3>Methods</h3><div>The data used for this study were obtained from the 2020 Somalia Health and Demographic Survey. A sample of 7462 newborn with their birth weight within five years preceding the survey was included. The newborns’ birth weight; which is first categorized in to three: low birth weight (&lt;2.5 kg), normal birth weight (2.5–4 kg) and high birth weight (&gt;4 kg), was considered as a response variable. The analysis was carried out using ordinal logistic regression and adjusted odds ratio with 95 % confidence interval and <em>p</em>-value &lt;0.05 was used to declare statistical significance.</div></div><div><h3>Results</h3><div>From the total of 7462 newborns include in the study, 1196 (16.03 %), 5304(71.08 %) and 962 (12.89 %) were born with low birth weight, normal birth weight and high birth weight, respectively. Maternal age (AOR = 1.48; 95 %CI: 1.12–1.956), having Antenatal care (ANC) visit (AOR = 1.24; 95 %CI: 1.09–1.41), gestational age <span><math><mo>≥</mo></math></span>37 weeks (AOR = 2.02; 95 % CI: 1.34–3.03), rich wealth index family (AOR = 1.46; 95 %CI: 1.29–1.65) and mother with secondary/higher educational level (AOR = 1.51; 95 %CI: 1.19–1.92) as well as place of residence were significantly associated with higher birth weight.</div></div><div><h3>Conclusion</h3><div>The results of this study showed that birth weight is significantly associated with mother age, ANC visit, mother educational level, wealth index, residence, and gestational age at birth. Significantly large proportions of newborn babies are born with low-birth weight and this might be duet to many factors. Since low birth weight is a strong indicator of multifaceted public health problem, the governmental and non- governmental organizations working on maternal health should focus on alleviating this public health burden by giving special attention for antenatal care utilization coverage and improve other maternal health.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100241"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonatal resuscitation skill among health care providers in Eastern Africa: A systematic review and meta-analysis","authors":"Addis Eyeberu,&nbsp;Elias Yadeta,&nbsp;Haymanot Mezmur,&nbsp;Aboma Motuma,&nbsp;Adera Debella","doi":"10.1016/j.gpeds.2025.100248","DOIUrl":"10.1016/j.gpeds.2025.100248","url":null,"abstract":"<div><h3>Background</h3><div>Neonatal resuscitation skills involve providing ventilation, clearing airways, performing chest compressions, and administering necessary interventions to stabilize newborns in distress. Although basic neonatal resuscitation has been shown to improve newborn survival rates, asphyxia-related neonatal mortality remains high. This is partly due to inadequate skills among healthcare providers, who also exhibit varying expertise in newborn resuscitation across the region. Therefore, this study aimed to assess the pooled level of neonatal resuscitation skills among healthcare providers and identify associated factors.</div></div><div><h3>Methods</h3><div>Articles were searched from major databases. Data were analyzed using Stata version 18 statistical software. The overall estimates with a 95 % confidence interval were estimated using a random effect model.</div></div><div><h3>Results</h3><div>A total of 7038 healthcare providers were included in this study. The overall pooled result revealed that the level of neonatal resuscitation skills among healthcare providers in Eastern Africa was 48 % [95 % CI: 34–62]. The highest and lowest pooled level of neonatal resuscitation skills was observed among studies conducted in Ethiopia 57 % (95 % CI: 38–74) and Somalia 14 % (95 % CI: 8–22) respectively. Trained in neonatal resuscitation (OR = 1.87, 95 % CI: 1.26, 2.48), age above 35 (OR = 0.16, 95 % CI:0.14, 0.42), and having good knowledge (OR = 2.08, 95 % CI: 1.31, 2.86) were significantly associated with neonatal resuscitation skill.</div></div><div><h3>Conclusions</h3><div>The level of neonatal resuscitation skills in Eastern Africa is generally low. Factors such as receiving training in neonatal resuscitation, possessing adequate knowledge, and being over the age of 35 were significantly associated with neonatal resuscitation skills. Therefore, strengthening both short-term and long-term training programs, along with regular updates on neonatal resuscitation protocols, can enhance healthcare providers' skills in this critical area.</div></div><div><h3>Implications for Clinical Skill</h3><div>Identifying and addressing skill gaps in neonatal resuscitation can enhance clinical competency among healthcare providers, leading to improved neonatal survival rates. Additionally, this study can inform the development of training programs, influence policies, and foster quality improvement initiatives in healthcare facilities.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100248"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143580642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact and frequency of misdiagnosis of appendicitis in pediatric patients with gastroenteritis in a developing country","authors":"Pastor Escárcega-Fujigaki ,&nbsp;Guillermo Hernández-Peredo-Rezk ,&nbsp;Gerardo Alonso-Acosta ,&nbsp;Keren-Hapuc Vargas-Amador","doi":"10.1016/j.gpeds.2025.100244","DOIUrl":"10.1016/j.gpeds.2025.100244","url":null,"abstract":"<div><h3>Aim</h3><div>Appendicitis manifests with atypical symptoms in a large percentage of patients, leading to diagnostic errors that delay diagnosis. This study aimed to evaluate the impact and frequency of appendicitis being incorrectly diagnosed as gastroenteritis in a developing country.</div></div><div><h3>Methods</h3><div>This prospective, comparative study included 207 pediatric patients with appendicitis divided into two groups: group A, with 117 (56.5 %) patients with diagnostic errors, and group B, with 90 (43.4 %) patients without diagnostic errors. Clinical, laboratory, and imaging data were compared using the Mann–Whitney tests, odds ratio (OR), and 95 % confidence interval (CI) with statistical significance set at <em>p</em>-value &lt;0.05.</div></div><div><h3>Results</h3><div>The diagnosis was confused with gastroenteritis in 66 (56.4 %) patients, causing a delay in surgical management, which was statistically significant (OR: 2.25; 95 % CI: 1.23–4.09; <em>p</em> &lt; 0.005) when compared with group B. The second most common cause of confusion was colitis, which was observed in 40 (34.2 %) patients. Group A had a large number of perforated appendicitis cases (OR: 3.22; 95 % CI: 1.81–5.72; <em>p</em> &lt; 0.01), with more days till oral administration initiation (OR: 3.68; 95 % CI: 1.32–10.27; <em>p</em> &lt; 0.01) and longer hospital stays (OR: 6.83; 95 % CI: 1.85–25.11; <em>p</em> &lt; 0.01). Furthermore, general practitioners more frequently had diagnostic errors than pediatricians (OR: 0.17; 95 % CI: 0.07–0.43; <em>p</em> &lt; 0.01).</div></div><div><h3>Conclusions</h3><div>The diagnosis of appendicitis was confused with gastroenteritis or colitis in majority of pediatric patients. Practitioners should be aware of the possibility of appendicitis in patients presenting with abdominal pain, diarrhea, or fever.</div></div><div><h3>Level of Evidence</h3><div>III</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100244"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The validity of lateral neck X-Ray for the diagnosis of retropharyngeal infection in pediatric patients","authors":"Yehonatan Adler ,&nbsp;Shani Blushtein-Levin ,&nbsp;Eli Somekh ,&nbsp;Yoram Ben-Yehuda ,&nbsp;Haim Bibi ,&nbsp;Nathan Peled ,&nbsp;Michael Wolf","doi":"10.1016/j.gpeds.2024.100235","DOIUrl":"10.1016/j.gpeds.2024.100235","url":null,"abstract":"<div><h3>Aim</h3><div>To examine the validity of lateral neck x ray (LNXR) for the diagnosis of retropharyngeal infection (RPI) in emergency room (ER) settings. Effectiveness of conservative treatment with IV antibiotics for RPI was also examined.</div></div><div><h3>Methods</h3><div>A retrospective analysis of patients diagnosed with RPI at a university-affiliated primary care center, between the years 2012–2022. Pre-vertebral space diameter at C2 level on LNXR was compared to a control group as well as before and after treatment. A sensitivity analysis was performed.</div></div><div><h3>Results</h3><div>44 and 20 patients were included in the study and control group, respectively. Median pre-vertebral thickness was significantly different between the groups (14.9 mm [IQR: 12.5, 18.4] vs. 4.1 mm [3.6, 5], <em>p</em> &lt; 0.001). Sensitivity and specificity of LNXR combined with clinical presentation for RPI diagnosis were 87 % and 74 %, respectively. Median pre-vertebral space diameter before and after treatment declined significantly (14.3 mm [12.3, 18.1] vs. 7.2 mm [4.6, 9.6], <em>p</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>LNXR is a good and valid modality for the diagnosis of RPI, in conjunction with clinical presentation in ER setting. IV antibiotics are efficient for most children with RPI. Neck CT and surgical intervention should be reserved for select patients.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100235"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep disturbances in hospitalized children: Comparison between acute admission and regular care units","authors":"Pia Burger ,&nbsp;Lindsay M.H. Steur ,&nbsp;Jorinde A.W. Polderman ,&nbsp;Reinoud J.B.J. Gemke","doi":"10.1016/j.gpeds.2024.100237","DOIUrl":"10.1016/j.gpeds.2024.100237","url":null,"abstract":"<div><h3>Introduction</h3><div>Hospitalization adversely affects children's sleep, primary due to disease-, staff-, psychosocial- and environment-related factors. Clustering discontinuity in Acute Admission Units (AAU's) appears to enhance efficiency in clinical care. However, sleep may be more affected in a pediatric AAU as compared to regular care units (RCUs).</div></div><div><h3>Methods</h3><div>In children of 1–12 years of age admitted to the AAU or RCUs, we used actigraphy to observe sleep, assessing Total Sleep Time (TST), Sleep Onset Latency (SOL), Wake After Sleep Onset (WASO), sleep efficiency, and awakenings. Subjective sleep quality was evaluated with PROMIS questionnaires. Sleep disturbances due to disease-, staff-, patient-, environment-, treatment-related factors were examined and compared between wards.</div></div><div><h3>Results</h3><div>Significant differences were observed between the AAU and RCUs in terms of specialty type and admission reasons: surgical patients and exacerbations of chronic diseases were more often admitted to RCUs. No significant differences were found between AAU and RCUs regarding TST (497 (92) (mean (SD)) vs 476 (96)), and WASO (113 (74) in both the AAU and RCU's). There was a trend towards more staff-related disturbances in the AAU (67 % vs 56 % <em>p</em> = 0.07, specifically regarding waking (32 % vs 22 %, <em>p</em> = 0.07). In all wards, sleep disturbances were reported by approximately 93 % of the patients.</div></div><div><h3>Conclusion</h3><div>Despite the concentration of clinical discontinuity to enhance efficiency of care in a novel pediatric AAU, no differences with regards to sleep (disturbances) were observed in comparison to the RCUs. Yet substantial sleep disturbances in both settings indicate the need for targeted interventions to improve inpatient sleep.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100237"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors of preterm birth in greater Accra regional hospital, ridge","authors":"Immanuel Adom-Miah ,&nbsp;Williams Ampadu Oduro ,&nbsp;David Boateng Appiah ,&nbsp;Theodocea Nortey","doi":"10.1016/j.gpeds.2025.100247","DOIUrl":"10.1016/j.gpeds.2025.100247","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to investigate the sociodemographic, psychological, cultural, environmental, and occupational risk factors associated with preterm birth at the Greater Accra Regional Hospital.</div></div><div><h3>Study Design</h3><div>A case-control study.</div></div><div><h3>Methods</h3><div>The study employed a case-control design and used the Chi-square test to assess associations between various risk factors and preterm birth. Sociodemographic, psychological, cultural, environmental, and occupational factors were examined to determine their relationship with preterm birth.</div></div><div><h3>Results</h3><div>The findings revealed a significant association between depression and preterm birth, with a Chi-square value of 12.115 and a p-value of 0.001. Moderate exercise was also associated with preterm birth, showing a significant relationship (p-value of 0.039). However, the mothers’ occupation, including posture at work, hours spent in a specific position, and exposure to heat, chemicals, dust, or smoke, did not demonstrate significant associations with preterm birth.</div></div><div><h3>Conclusions</h3><div>The study emphasizes the need for enhanced maternal and child healthcare efforts in the country and underscores the importance of public education, particularly regarding the role of partner support in reducing the risk of preterm birth.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100247"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143561890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}