Global pediatrics最新文献

{"title":"The first thousand days: nourishing the developing brain for a lifetime of mental well-being. Narrative review","authors":"Massimo Pettoello-Mantovani , Donjeta Bali , Esra Sevketoglu , Maria Pastore , Mehmet Vural , Ida Giardino","doi":"10.1016/j.gpeds.2025.100270","DOIUrl":"10.1016/j.gpeds.2025.100270","url":null,"abstract":"","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100270"},"PeriodicalIF":0.0,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144702966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of dengue severity scores for shock prediction: A pediatric cohort in the Mekong Delta, Vietnam","authors":"Ly Cong Tran,&nbsp;Phuong Minh Nguyen,&nbsp;Toan Khanh Nguyen,&nbsp;Tam Phuong Nguyen,&nbsp;Ngan Nguyen Quynh Tran,&nbsp;Tien Hoang Vo,&nbsp;Kim Vo Thien Pham,&nbsp;Vinh Tri Lam,&nbsp;Huong Thien Mai,&nbsp;My Hoang Le","doi":"10.1016/j.gpeds.2025.100272","DOIUrl":"10.1016/j.gpeds.2025.100272","url":null,"abstract":"<div><h3>Background</h3><div>Dengue shock syndrome (DSS) is a life-threatening complication of dengue infection, particularly in children. Early identification of those at risk of progression to DSS is essential for improving outcomes, especially in resource-limited settings such as Vietnam. This study aimed to determine the utility of three dengue scoring systems—Pongpan 2013 (Score I), Srisuphanunt 2022 (Score II), and a modified Bhaskar 2022 (Score III)—in predicting DSS in pediatric patients by systematically assessing their discrimination and calibration.</div></div><div><h3>Methods</h3><div>This cohort study included children aged ≤ 16 years with dengue infection, admitted to a central hospital in the Mekong Delta region between December 2022 and October 2024. The predictive utility of three scoring systems was evaluated using measures of discrimination and calibration. Discrimination was evaluated using area under the receiver operating characteristic curve (AUC), and calibration was assessed using the Hosmer-Lemeshow test, calibration plots, mean absolute error (MAE), and 90th percentile of absolute calibration error (P90).</div></div><div><h3>Results</h3><div>Among the studied patients, 25.0 % progressed to DSS. The median day of illness at admission was 4 (interquartile range: 2–4). All three scores demonstrated excellent discrimination: Score (I), AUC = 0.916 (95 % CI: 0.865–0.967); Score (II), AUC = 0.897 (95 % CI: 0.842–0.951); Score (III), AUC = 0.849 (95 % CI: 0.781–0.918); all <em>p</em> &lt; 0.001. Calibration was best in Score (III), with χ²(<em>df</em>) = 2.24(3), <em>p</em> = 0.524, MAE = 0.036, and P90 = 0.094. Score (I) and Score (II) showed poorer calibration, with significant Hosmer-Lemeshow p-values and higher error metrics.</div></div><div><h3>Conclusion</h3><div>Score (III) demonstrates balanced predictive performance and may aid early DSS risk stratification in pediatric dengue. Further validation in diverse settings is needed before routine use. Scoring systems should complement, not replace, continuous clinical monitoring.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100272"},"PeriodicalIF":0.0,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144686528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Educating on differences to prevent violence gender-based (EDVIGE): a project for the primary prevention of gender-based violence during adolescence","authors":"Anna Libera Latino ,&nbsp;Maria Teresa Vaccaro ,&nbsp;Giuseppina Volpicelli ,&nbsp;Michele Zamboni","doi":"10.1016/j.gpeds.2025.100269","DOIUrl":"10.1016/j.gpeds.2025.100269","url":null,"abstract":"<div><div>Gender-based violence is any act of violence based on gender that causes physical, sexual, or psychological harm or suffering to women, including threats, coercion, or arbitrary deprivation of liberty. It represents a major global health issue.</div><div>Although this phenomenon most frequently manifests itself within emotional, familial, and/or friendly relationships, it actually concerns society as a whole. It must be considered a structural problem—not just a situational or emergency issue—and should be addressed with a scientific approach and through urgent, coordinated measures.</div><div>It is therefore essential to educate girls and boys from an early age to understand the importance of mutual respect, listening, and appreciation of others’ differences. They must be provided with tools to recognize and avoid gender-based violence.</div><div>The EDVIGE Project by the VìOLA Dauna Volunteer Organization proposes an operational model to raise awareness among students, teachers, and educators about the early recognition of risk factors and/or warning signs of gender-based violence, in order to prevent the psycho-physical and social consequences stemming from unhealthy relationships, both within and outside the family context.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100269"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk prediction of healthcare-associated neonatal sepsis in Amhara, Ethiopia: A prospective cohort study","authors":"Nadine Najjar ,&nbsp;Abebe Gebremariam Gobezayehu ,&nbsp;Joseph Hopkins ,&nbsp;Heran Biza ,&nbsp;Habib Yakubu ,&nbsp;Lindsay Denny ,&nbsp;Mulusew Lijalem ,&nbsp;Lamesgin Alamineh Endalamaw ,&nbsp;Yakob S. Ahmed ,&nbsp;Taye Zeru Tadege ,&nbsp;Mekuanint Wasihun Endalew ,&nbsp;Yichalal Endayehu Tafere ,&nbsp;Gurmesa Tura Debelew ,&nbsp;Erin Stone ,&nbsp;Christine L. Moe ,&nbsp;John N. Cranmer","doi":"10.1016/j.gpeds.2025.100268","DOIUrl":"10.1016/j.gpeds.2025.100268","url":null,"abstract":"<div><h3>Background</h3><div>Neonatal sepsis is a major contributor to neonatal mortality in low- and middle-income countries. Globally, rapid diagnosis and treatment are often a challenge, and standard antibiotic therapy is threatened by antimicrobial resistance (AMR). This study quantifies the predictors of healthcare-associated neonatal sepsis in Amhara, Ethiopia.</div></div><div><h3>Methods</h3><div>This prospective cohort study recruited normal and low birth weight (LBW) neonates from two hospitals. Neonates with suspected healthcare-associated sepsis had blood cultures drawn to identify the organisms and AMR patterns. We used univariable and multivariable logistic regression to determine risk factors for culture-confirmed sepsis. Next, we performed marginal effects analysis to create a clinical tool for prospectively measuring newborn sepsis risk.</div></div><div><h3>Results</h3><div>Twenty percent of 605 neonates developed healthcare-associated, culture-confirmed sepsis. 44.9% were resistant to first-line empiric therapy, and only 4% of those who failed first-line drugs had sepsis organisms susceptible to second-line drugs. Multivariable logistic regression identified five primary predictors: LBW (aOR 3.4), twin birth (aOR 4.7), maternal history of preterm births (aOR 2.7) or history of LBW births (aOR 2.6), low family income (aOR 1.7), and birth at the general hospital (aOR 2.5). There were significant differences in sepsis and mortality by facility and birthweight.</div></div><div><h3>Conclusions</h3><div>Neonatal sepsis and AMR pose significant risk to our study population. Due to the high proportion of AMR and likelihood of treatment failure, developing effective facility-based sepsis prevention strategies is an urgent priority for advancing newborn survival in Amhara, Ethiopia and in similar global contexts.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100268"},"PeriodicalIF":0.0,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144686527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychobiotic properties of probiotic lactic acid bacteria and bifidobacteria in paediatric neurological disorders","authors":"Maria Teresa Rocchetti ,&nbsp;Mariagiovanna Di Chiano ,&nbsp;Iman Elouardi ,&nbsp;Daniela Fiocco","doi":"10.1016/j.gpeds.2025.100266","DOIUrl":"10.1016/j.gpeds.2025.100266","url":null,"abstract":"<div><div>Recent studies have highlighted a close relationship between intestinal dysbiosis and paediatric neurological disorders, such as autism spectrum disorders (ASD), attention deficit hyperactivity disorder (ADHD), epilepsy, cerebral palsy (CP). In the last decades, the relevance of a strong connection between the intestinal microbiota and the brain, i.e., the gut-brain axis, has been broadly ascertained. Through this association, gut microbes contribute to shape development, physiology, and cognitive functions of the brain. The bidirectional communication between gut microbiota and brain involves a complex set of molecular signals that influence synaptic plasticity, learning, memory, mood, and the brain's excitatory-inhibitory balance. Microbial metabolites play a fundamental role in modulating brain activity. Emerging scientific evidence suggests that neurological and psychiatric conditions, including ASD, ADHD, anxiety, and depression, may not simply stem from brain malfunctions, but rather from imbalances in the gut microbiota, which contribute to disrupt brain function and development. In this context, psychobiotics, i.e., a specific group of probiotic microorganisms, have garnered interest for their potential to modulate brain functions. Several pre-clinical studies on psychobiotics have shown promising results in managing paediatric neurological disorders, including ASD and ADHD. However, there is only a limited number of clinical studies to support the use of psychobiotics as therapeutics. This review summarizes and discusses the link between gut microbiota and neurological disorders in children, and the current status of studies investigating the potential application of psychobiotic lactic acid bacteria (LAB) and bifidobacteria for treating these paediatric disorders.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100266"},"PeriodicalIF":0.0,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144595657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measles vaccination dropout and its associated factors among children aged 15-23 months in Qardho district, Northeastern Somalia: A community-based cross-sectional study","authors":"Mohamed Yusuf ,&nbsp;Agumasie Semahegn ,&nbsp;Gezahegn Tesfaye ,&nbsp;Maleda Tefera","doi":"10.1016/j.gpeds.2025.100267","DOIUrl":"10.1016/j.gpeds.2025.100267","url":null,"abstract":"<div><h3>Background</h3><div>Although childhood vaccination is highly effective in preventing measles infection, dropout from the vaccination schedule remains a significant public health challenge in Low- and Middle-Income countries, including Somalia. There is a paucity of research evidence on the magnitude and the factors contributing to it in the study setting. Therefore, this study aimed to assess the magnitude of measles vaccination dropout and its associated factors among children aged 15–23 months in Qardho district, Northeastern, Somalia.</div></div><div><h3>Method</h3><div>A community-based cross-sectional study was conducted among 372 randomly selected participants who live in Qardho district, Northeastern Somalia. Data were collected using a structured tool developed in an Open Data Kit and exported to Stata version 17.0 for cleaning and analysis. Descriptive statistics were used to summarize the data. Bivariable and multivariable logistic regression analyses were performed to identify factors associated with children’s dropout from measles vaccination. Adjusted odds ratio at a 95 % confidence interval was used to declare statistically significant associations.</div></div><div><h3>Results</h3><div>The overall magnitude of measles vaccination dropout was 42.5 % (95 % CI: 37.3, 47.6 %). Children with a birth order of 2–4 (AOR = 3.09, 95 % CI: 1.38, 6.94), and ≥ 5 (AOR = 4.25, 95 % CI: 1.90, 9.48), born to a merchant mother (AOR = 3.63, 95 % CI: 1.64, 8.04), and whose mothers/caregivers had a negative attitude towards vaccination (AOR = 3.82, 95 % CI: 2.18, 6.69) were more likely to dropout from measles vaccination. Children whose mothers attended at least primary level of education (AOR = 0.28, 95 % CI: 0.12, 0.68), whose fathers attended primary education and above (AOR = 0.25, 95 % CI: 0.08, 0.81), and children from middle-income families (AOR = 0.32, 95 % CI: 0.13, 0.79) were less likely to experience measles vaccination dropout.</div></div><div><h3>Conclusion</h3><div>The findings of this study highlight that two in five children dropped out of the measles vaccine program. Parental educational status, attitude towards vaccination, mother’s occupation, family income and child’s birth order were significantly associated with measles vaccination dropout. Future intervention strategies could focus on promoting a positive attitude towards the vaccine.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100267"},"PeriodicalIF":0.0,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144665827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rising incidence of feticide, neonaticide, and infanticide in Pakistan: An emerging crisis","authors":"Muneeb Saifullah ,&nbsp;Fatima Yasin ,&nbsp;Mishal Ihsan ,&nbsp;Qasim Mehmood ,&nbsp;Syed Ali Ahsan ,&nbsp;Abbas M Mehdi ,&nbsp;Javed Iqbal","doi":"10.1016/j.gpeds.2025.100265","DOIUrl":"10.1016/j.gpeds.2025.100265","url":null,"abstract":"<div><div>Feticide, neonaticide, and infanticide are serious crimes under the law; however, they remain prevalent in South Asian countries, including Pakistan. Female feticide is much more common due to a preference for males based on social, economic, and cultural needs. Other contributing factors include poverty, Low literacy, honor killings, and unwanted or illegal pregnancies. Police rarely pursue these cases. This lack of accountability emboldens perpetrators and silences survivors. By improving education, health services, economic conditions, and legal accountability, Pakistan can begin to reduce the tragic incidence of feticide, neonaticide, and infanticide.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100265"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144604557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns of multi-morbidity cluster for under five children in Tanzania","authors":"Marystella Vicent,&nbsp;Maurice C.Y. Mbago,&nbsp;Amina S. Msengwa","doi":"10.1016/j.gpeds.2025.100264","DOIUrl":"10.1016/j.gpeds.2025.100264","url":null,"abstract":"<div><h3>Background</h3><div>Despite progress in child health interventions, anemia, malaria, and fever remain prominent public health concerns for children under five in Tanzania. Geographic variability may influence disease patterns, necessitating the identification of high-risk clusters to inform targeted interventions. This study aimed to assess the spatial clustering of these three conditions among Tanzanian under-five children using three nationally representative surveys.</div></div><div><h3>Methods</h3><div>A cross-sectional, survey-based design was employed using data from the 2007–08 and 2011–12 Tanzania HIV/AIDS and Malaria Indicator Surveys (THMIS) and the 2015–16 Tanzania Demographic and Health Survey and Malaria Indicator Survey (TDHS-MIS). In total, 19,832 under-five children were included across the three surveys. Prevalences of anemia, malaria, and fever were determined, and spatial analyses were performed using STATA version 16, ArcGIS version 10.3, and SaTScan software. Moran’s I was calculated to test spatial autocorrelation, and the SaTScan Bernoulli model identified clusters with elevated risks.</div></div><div><h3>Results</h3><div>Overall, 5551 children from the 2007–08 THMIS, 6458 from the 2011–12 THMIS, and 7823 from the 2015–16 TDHS-MIS were analyzed. Anemia was the most prevalent condition, with rates ranging from 57.4 % to 69.7 %, followed by fever (18.6 % to 22.4 %), and malaria (9.3 % to 12.5 %). Spatial autocorrelation tests indicated non-random clustering for these conditions, with Moran’s I values ranging from 0.538 to 0.975 (<em>p</em> &lt; 0.001). SaTScan analyses revealed recurrent high-risk clusters in Kigoma, Ruvuma, Lindi, and Mtwara across the three surveys. These clusters were statistically significant (<em>p</em> &lt; 0.001) and highlighted persistent hotspots of childhood morbidity.</div></div><div><h3>Conclusion</h3><div>The study demonstrates pronounced spatial clustering of anemia, malaria, and fever among under-five children in Tanzania. Key regions including Kigoma, Ruvuma, Lindi, and Mtwara consistently emerged as hotspots. Targeted health interventions in these high-risk areas, including integrated approaches addressing multiple coexisting conditions, are critical for reducing disease burden and improving child health outcomes.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100264"},"PeriodicalIF":0.0,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144579952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 6.2 Kg macrosomia in a non-diabetic mother managed with no adverse outcomes in a resource limited setting: A case report","authors":"Farhan Yusuf Sharif ,&nbsp;Abdiwali mohamed Ahmed ,&nbsp;Abdikafi Ibrahim Khayre ,&nbsp;Mohamed Hassan Osman ,&nbsp;Joshua Muhumuza","doi":"10.1016/j.gpeds.2025.100262","DOIUrl":"10.1016/j.gpeds.2025.100262","url":null,"abstract":"<div><h3>Introduction and importance</h3><div>When a baby's birth weight surpasses the 90th percentile for a certain gestational week, it is referred to as macrosomia. The growing prevalence of fetal macrosomia presents an impending concern in the field of obstetrics. Numerous complications for both the mother and the fetus are linked to macrosomia. We present a case of macrosomia that weighed 6.2 kg, delivered in a low resource setting in which no early neonatal or maternal complication occurred.</div></div><div><h3>Case presentation</h3><div>We present a 41-year-old woman gravida 8 para 7 + 0 that presented at 42 weeks of amenorrhea. On examination at admission, the body mass index was 42.5kg/m2, Ultrasonography was suggestive of severe oligohydramnios with an estimated fetal weight of 5.5 kg. The decision to deliver the baby by an elective cesarean section was made. The baby weighed 6.2 kg and did not have any physical abnormalities. At discharge, both the mother and baby were healthy.</div></div><div><h3>Clinical discussion</h3><div>A positive outcome requires tailored therapy for each patient because macrosomia is linked to numerous maternal and fetal complications.</div></div><div><h3>Conclusion</h3><div>Making a timely decision to have a cesarean delivery when indicated, as was done in this instance, can lower the rate of maternal and neonatal morbidity.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100262"},"PeriodicalIF":0.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144271726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome and its predictors of children with nosocomial infection in ayder pediatric ICU, Tigray, Ethiopia","authors":"Hansa Haftu Lemma ,&nbsp;Abdikarin Ahmed Mohamed ,&nbsp;Amanuel Hadgu ,&nbsp;Teklu Gebrehiwot Gebremichael","doi":"10.1016/j.gpeds.2025.100263","DOIUrl":"10.1016/j.gpeds.2025.100263","url":null,"abstract":"<div><h3>Objective</h3><div>The main objectives of this study were to assess the outcomes and predictors of nosocomial infections in pediatric patients.</div></div><div><h3>Method</h3><div>A hospital-based retrospective observational study and a consecutive sampling technique were used to collect data. Categorical data were compared using Pearson’s Chi-square test/Fisher’s exact test. Additionally, Kaplan-Meier analysis was also used to assess survival. P-values &lt; 0.05 were considered statistically significant.</div></div><div><h3>Results</h3><div>A total of 45 patients who developed nosocomial infections were analyzed. The incidence density of nosocomial infection was 41.1 per 1000 patient-days. Most patients were male (53.3 %) and under 14 (75.6 %), with a median age of 1 year. Statistically significant variables associated with increased mortality included female gender, transfer from the ward, prolonged maintenance fluid duration (&gt;3 days), the need for mechanical ventilation, and the presence of comorbid illnesses, as indicated by chi-square analysis. Patients with nosocomial infections had a longer hospital stay (20 days vs. 10 days) and a higher mortality rate (26.7 % vs. 19.1 %) compared to those without nosocomial infections. Nosocomial infections resulted in an excess crude mortality rate of 7.5 %.</div></div><div><h3>Conclusion</h3><div>Preventive measures should be prioritized given the identified risk factors for nosocomial infections. Patients with nosocomial infections are at an increased risk of mortality.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100263"},"PeriodicalIF":0.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144261376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}