Global pediatrics最新文献

{"title":"The pivotal role of mental health in child and adolescent development","authors":"Agnese Suppiej ,&nbsp;Isabella Longo ,&nbsp;Massimo Pettoello-Mantovani","doi":"10.1016/j.gpeds.2025.100277","DOIUrl":"10.1016/j.gpeds.2025.100277","url":null,"abstract":"<div><div>Mental health in childhood and adolescence is a complex and evolving concept that goes far beyond the absence of mental illness. It involves achieving critical developmental and emotional milestones, building strong social skills that foster positive relationships, and cultivating resilience through effective coping strategies for life’s challenges. Recognizing mental health as a dynamic process, this view underscores its continuous evolution as young people grow and interact with their surroundings.</div><div>This commentary is prepared by the coordinators of the meeting on the importance of promoting child mental health, held on 9 November 2024 in Piazzola sul Brenta, Padua, Italy. The event was promoted and supported by the <em>GE Ghirardi Foundation</em> in collaboration with the Union of National European Pediatric Societies and Associations (EPA-UNEPSA), as part of the global initiatives marking World Mental Health Day 2024.</div><div>The initiative seeks to raise awareness—among healthcare professionals, educators, policymakers, and the wider public—about the essential role of mental health in the overall development of children and adolescents. The commentary provides a concise overview of the key determinants that support a healthy transition to adulthood and highlights the pressing need to protect and nurture the mental well-being of young people during this critical stage of life.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100277"},"PeriodicalIF":0.0,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144722335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The persistent shadow of disparity across the Atlantic: child health determinants and policy implications in Europe and North America","authors":"Antonio D’Avino ,&nbsp;Angel Carrasco-Sanz ,&nbsp;Anna Libera Latino ,&nbsp;Maria Pastore ,&nbsp;Ida Giardino ,&nbsp;Massimo Pettoello-Mantovani ,&nbsp;Francesca Scaltrito ,&nbsp;Domenico Adduce ,&nbsp;Maria Teresa Grimaldi ,&nbsp;Luigi Nigri","doi":"10.1016/j.gpeds.2025.100276","DOIUrl":"10.1016/j.gpeds.2025.100276","url":null,"abstract":"<div><div>Child health serves as a critical barometer of a society's well-being, yet profound disparities persist globally, stemming from \"unequal beginnings\" rooted in socioeconomic, environmental, and systemic factors. This brief review examines the complex determinants of child health inequities across Europe and draws comparisons with the United States. In Europe, despite historical health gains, stagnation and widening gaps are observed in child mortality, chronic illnesses, and mental health, exacerbated by poverty, educational disparities, and fragmented healthcare systems. A significant barrier to effective policy is the pervasive lack of consistent and comparable child health data. In the United States, similar socioeconomic disparities are compounded by deep-seated racial inequities in healthcare access and quality, highlighting the pervasive influence of structural factors beyond insurance coverage. Emerging challenges, such as the escalating burden of mental health conditions, lifestyle-related diseases, and the disproportionate impact of climate change through \"systemic cooling poverty,\" present new complexities. Artificial intelligence offers transformative potential for pediatric care but also carries risks of exacerbating existing disparities if not ethically and equitably implemented. Addressing these multifaceted challenges necessitates a concerted, multi-sectoral approach, emphasizing child-centric integrated care, robust data systems, and sustained political commitment to dismantle the systemic roots of inequity.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100276"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Baby wipes with a mildly acidic, pH-buffering system provided better skin condition compared to cotton washcloth and water in two randomized clinical trials","authors":"Robert J. O’Connor ,&nbsp;Lisa Bohman ,&nbsp;Susanna Brink ,&nbsp;Andrew N. Carr ,&nbsp;Roger D. Gibb ,&nbsp;Ioannis Hatzopoulos ,&nbsp;Dirk Van Gysel ,&nbsp;Stephanie Christen-Zaech","doi":"10.1016/j.gpeds.2025.100274","DOIUrl":"10.1016/j.gpeds.2025.100274","url":null,"abstract":"<div><h3>Objectives</h3><div>Two parallel studies compared the skin health effects of two different baby wipes products to the use of 100 % cotton washcloth and water (WCW). Two wipe products with lotions of 99 % purified water and acidic, pH-buffering systems were tested. The primary objective was to compare the wipes products to the WCW treatment based on severity of erythema, skin barrier integrity (Trans-epidermal Water Loss; TEWL) and pH of skin in the diapered area.</div></div><div><h3>Methods</h3><div>The two studies were prospective, randomized, blinded, parallel-design studies. The first study enrolled 110 babies approximately 3–9 months of age, and the second study enrolled 106 babies up to 36 months of age. The 14-day product use period was preceded by a 7-day washout period. Erythema grading was done at the perianal area, genitals, intertriginous areas, and the buttocks. TEWL and skin pH measurements were done at the genitals and buttocks, with an additional pH measurement taken at the perineum in the second study.</div></div><div><h3>Results</h3><div>Both baby wipe products resulted in significantly lower erythema scores at the perianal region, with Wipe A also being significantly lower at the genital regions compared to WCW. Skin barrier integrity, measured by TEWL, was better for Wipe A at both 7 and 14 days of use with statistical significance achieved at day 14. No TEWL differences were seen for Wipe B versus WCW. Skin pH was significantly lower than WCW at both perianal region and genitals at both 7 and 14 days of use for both wipes, and at Perineum for Wipe B.</div></div><div><h3>Conclusion</h3><div>Based on the results, the baby wipes were shown to be at least as mild as WCW to baby’s skin as measured by lower mean erythema scores and healthy barrier (lower or equal TEWL). The wipes may also provide potential long-term skin health benefits derived from a lower steady-state skin pH.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100274"},"PeriodicalIF":0.0,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144738350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The first thousand days: nourishing the developing brain for a lifetime of mental well-being. Narrative review","authors":"Massimo Pettoello-Mantovani ,&nbsp;Donjeta Bali ,&nbsp;Esra Sevketoglu ,&nbsp;Maria Pastore ,&nbsp;Mehmet Vural ,&nbsp;Ida Giardino","doi":"10.1016/j.gpeds.2025.100270","DOIUrl":"10.1016/j.gpeds.2025.100270","url":null,"abstract":"","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100270"},"PeriodicalIF":0.0,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144702966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double burden of malnutrition among under-5 children in Garo ethnic community of Bangladesh: Prevalence and determinants","authors":"M. M. Mehedi Hasan ,&nbsp;Nayeem Rahman ,&nbsp;Farzana Afroz ,&nbsp;Md. Nazrul Islam ,&nbsp;Md. Serajus Saberin ,&nbsp;Md. Tohin Hossain Somon ,&nbsp;Md Reaz Ul Islam","doi":"10.1016/j.gpeds.2025.100273","DOIUrl":"10.1016/j.gpeds.2025.100273","url":null,"abstract":"<div><h3>Background</h3><div>Malnutrition, especially in children, continues to be a serious public health concern worldwide. This study investigates the prevalence and risk factors of the double burden of malnutrition—undernutrition and overnutrition—among Garo under-five children in Sherpur, Bangladesh, where they reside most.</div></div><div><h3>Methods</h3><div>A community-based cross-sectional study was conducted from January to April 2024, involving 336 Garo children aged 6 to 59 months. Data were collected through structured interviews with mothers and anthropometric measurements of children. Descriptive statistics, bivariate and multivariable logistic regression analyses were performed to assess associations between malnutrition indicators and sociodemographic factors.</div></div><div><h3>Results</h3><div>Stunting (27.98 %) was the most prevalent form of malnutrition, followed by underweight (7.74 %), wasting (4.46 %), and overweight (7.74 %). Male children had significantly higher odds of stunting (AOR = 1.80, <em>p</em> = 0.032), and children from households with lower food expenditures (&lt;500 BDT per day) were at greater risk of stunting (AOR = 4.03, <em>p</em> = 0.016). The odds of being overweight were 8.91 times greater for older children (48–59 months) (<em>p</em> = 0.005), which indicated a significant association.</div></div><div><h3>Conclusions</h3><div>The study highlights the coexistence of undernutrition and overnutrition among Garo children, emphasizing the urgent need for targeted interventions. Addressing the double burden of malnutrition through culturally tailored programs and policy interventions is essential to improving child health in ethnic communities.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100273"},"PeriodicalIF":0.0,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144711645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of dengue severity scores for shock prediction: A pediatric cohort in the Mekong Delta, Vietnam","authors":"Ly Cong Tran,&nbsp;Phuong Minh Nguyen,&nbsp;Toan Khanh Nguyen,&nbsp;Tam Phuong Nguyen,&nbsp;Ngan Nguyen Quynh Tran,&nbsp;Tien Hoang Vo,&nbsp;Kim Vo Thien Pham,&nbsp;Vinh Tri Lam,&nbsp;Huong Thien Mai,&nbsp;My Hoang Le","doi":"10.1016/j.gpeds.2025.100272","DOIUrl":"10.1016/j.gpeds.2025.100272","url":null,"abstract":"<div><h3>Background</h3><div>Dengue shock syndrome (DSS) is a life-threatening complication of dengue infection, particularly in children. Early identification of those at risk of progression to DSS is essential for improving outcomes, especially in resource-limited settings such as Vietnam. This study aimed to determine the utility of three dengue scoring systems—Pongpan 2013 (Score I), Srisuphanunt 2022 (Score II), and a modified Bhaskar 2022 (Score III)—in predicting DSS in pediatric patients by systematically assessing their discrimination and calibration.</div></div><div><h3>Methods</h3><div>This cohort study included children aged ≤ 16 years with dengue infection, admitted to a central hospital in the Mekong Delta region between December 2022 and October 2024. The predictive utility of three scoring systems was evaluated using measures of discrimination and calibration. Discrimination was evaluated using area under the receiver operating characteristic curve (AUC), and calibration was assessed using the Hosmer-Lemeshow test, calibration plots, mean absolute error (MAE), and 90th percentile of absolute calibration error (P90).</div></div><div><h3>Results</h3><div>Among the studied patients, 25.0 % progressed to DSS. The median day of illness at admission was 4 (interquartile range: 2–4). All three scores demonstrated excellent discrimination: Score (I), AUC = 0.916 (95 % CI: 0.865–0.967); Score (II), AUC = 0.897 (95 % CI: 0.842–0.951); Score (III), AUC = 0.849 (95 % CI: 0.781–0.918); all <em>p</em> &lt; 0.001. Calibration was best in Score (III), with χ²(<em>df</em>) = 2.24(3), <em>p</em> = 0.524, MAE = 0.036, and P90 = 0.094. Score (I) and Score (II) showed poorer calibration, with significant Hosmer-Lemeshow p-values and higher error metrics.</div></div><div><h3>Conclusion</h3><div>Score (III) demonstrates balanced predictive performance and may aid early DSS risk stratification in pediatric dengue. Further validation in diverse settings is needed before routine use. Scoring systems should complement, not replace, continuous clinical monitoring.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100272"},"PeriodicalIF":0.0,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144686528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Educating on differences to prevent violence gender-based (EDVIGE): a project for the primary prevention of gender-based violence during adolescence","authors":"Anna Libera Latino ,&nbsp;Maria Teresa Vaccaro ,&nbsp;Giuseppina Volpicelli ,&nbsp;Michele Zamboni","doi":"10.1016/j.gpeds.2025.100269","DOIUrl":"10.1016/j.gpeds.2025.100269","url":null,"abstract":"<div><div>Gender-based violence is any act of violence based on gender that causes physical, sexual, or psychological harm or suffering to women, including threats, coercion, or arbitrary deprivation of liberty. It represents a major global health issue.</div><div>Although this phenomenon most frequently manifests itself within emotional, familial, and/or friendly relationships, it actually concerns society as a whole. It must be considered a structural problem—not just a situational or emergency issue—and should be addressed with a scientific approach and through urgent, coordinated measures.</div><div>It is therefore essential to educate girls and boys from an early age to understand the importance of mutual respect, listening, and appreciation of others’ differences. They must be provided with tools to recognize and avoid gender-based violence.</div><div>The EDVIGE Project by the VìOLA Dauna Volunteer Organization proposes an operational model to raise awareness among students, teachers, and educators about the early recognition of risk factors and/or warning signs of gender-based violence, in order to prevent the psycho-physical and social consequences stemming from unhealthy relationships, both within and outside the family context.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100269"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk prediction of healthcare-associated neonatal sepsis in Amhara, Ethiopia: A prospective cohort study","authors":"Nadine Najjar ,&nbsp;Abebe Gebremariam Gobezayehu ,&nbsp;Joseph Hopkins ,&nbsp;Heran Biza ,&nbsp;Habib Yakubu ,&nbsp;Lindsay Denny ,&nbsp;Mulusew Lijalem ,&nbsp;Lamesgin Alamineh Endalamaw ,&nbsp;Yakob S. Ahmed ,&nbsp;Taye Zeru Tadege ,&nbsp;Mekuanint Wasihun Endalew ,&nbsp;Yichalal Endayehu Tafere ,&nbsp;Gurmesa Tura Debelew ,&nbsp;Erin Stone ,&nbsp;Christine L. Moe ,&nbsp;John N. Cranmer","doi":"10.1016/j.gpeds.2025.100268","DOIUrl":"10.1016/j.gpeds.2025.100268","url":null,"abstract":"<div><h3>Background</h3><div>Neonatal sepsis is a major contributor to neonatal mortality in low- and middle-income countries. Globally, rapid diagnosis and treatment are often a challenge, and standard antibiotic therapy is threatened by antimicrobial resistance (AMR). This study quantifies the predictors of healthcare-associated neonatal sepsis in Amhara, Ethiopia.</div></div><div><h3>Methods</h3><div>This prospective cohort study recruited normal and low birth weight (LBW) neonates from two hospitals. Neonates with suspected healthcare-associated sepsis had blood cultures drawn to identify the organisms and AMR patterns. We used univariable and multivariable logistic regression to determine risk factors for culture-confirmed sepsis. Next, we performed marginal effects analysis to create a clinical tool for prospectively measuring newborn sepsis risk.</div></div><div><h3>Results</h3><div>Twenty percent of 605 neonates developed healthcare-associated, culture-confirmed sepsis. 44.9% were resistant to first-line empiric therapy, and only 4% of those who failed first-line drugs had sepsis organisms susceptible to second-line drugs. Multivariable logistic regression identified five primary predictors: LBW (aOR 3.4), twin birth (aOR 4.7), maternal history of preterm births (aOR 2.7) or history of LBW births (aOR 2.6), low family income (aOR 1.7), and birth at the general hospital (aOR 2.5). There were significant differences in sepsis and mortality by facility and birthweight.</div></div><div><h3>Conclusions</h3><div>Neonatal sepsis and AMR pose significant risk to our study population. Due to the high proportion of AMR and likelihood of treatment failure, developing effective facility-based sepsis prevention strategies is an urgent priority for advancing newborn survival in Amhara, Ethiopia and in similar global contexts.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100268"},"PeriodicalIF":0.0,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144686527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychobiotic properties of probiotic lactic acid bacteria and bifidobacteria in paediatric neurological disorders","authors":"Maria Teresa Rocchetti ,&nbsp;Mariagiovanna Di Chiano ,&nbsp;Iman Elouardi ,&nbsp;Daniela Fiocco","doi":"10.1016/j.gpeds.2025.100266","DOIUrl":"10.1016/j.gpeds.2025.100266","url":null,"abstract":"<div><div>Recent studies have highlighted a close relationship between intestinal dysbiosis and paediatric neurological disorders, such as autism spectrum disorders (ASD), attention deficit hyperactivity disorder (ADHD), epilepsy, cerebral palsy (CP). In the last decades, the relevance of a strong connection between the intestinal microbiota and the brain, i.e., the gut-brain axis, has been broadly ascertained. Through this association, gut microbes contribute to shape development, physiology, and cognitive functions of the brain. The bidirectional communication between gut microbiota and brain involves a complex set of molecular signals that influence synaptic plasticity, learning, memory, mood, and the brain's excitatory-inhibitory balance. Microbial metabolites play a fundamental role in modulating brain activity. Emerging scientific evidence suggests that neurological and psychiatric conditions, including ASD, ADHD, anxiety, and depression, may not simply stem from brain malfunctions, but rather from imbalances in the gut microbiota, which contribute to disrupt brain function and development. In this context, psychobiotics, i.e., a specific group of probiotic microorganisms, have garnered interest for their potential to modulate brain functions. Several pre-clinical studies on psychobiotics have shown promising results in managing paediatric neurological disorders, including ASD and ADHD. However, there is only a limited number of clinical studies to support the use of psychobiotics as therapeutics. This review summarizes and discusses the link between gut microbiota and neurological disorders in children, and the current status of studies investigating the potential application of psychobiotic lactic acid bacteria (LAB) and bifidobacteria for treating these paediatric disorders.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100266"},"PeriodicalIF":0.0,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144595657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measles vaccination dropout and its associated factors among children aged 15-23 months in Qardho district, Northeastern Somalia: A community-based cross-sectional study","authors":"Mohamed Yusuf ,&nbsp;Agumasie Semahegn ,&nbsp;Gezahegn Tesfaye ,&nbsp;Maleda Tefera","doi":"10.1016/j.gpeds.2025.100267","DOIUrl":"10.1016/j.gpeds.2025.100267","url":null,"abstract":"<div><h3>Background</h3><div>Although childhood vaccination is highly effective in preventing measles infection, dropout from the vaccination schedule remains a significant public health challenge in Low- and Middle-Income countries, including Somalia. There is a paucity of research evidence on the magnitude and the factors contributing to it in the study setting. Therefore, this study aimed to assess the magnitude of measles vaccination dropout and its associated factors among children aged 15–23 months in Qardho district, Northeastern, Somalia.</div></div><div><h3>Method</h3><div>A community-based cross-sectional study was conducted among 372 randomly selected participants who live in Qardho district, Northeastern Somalia. Data were collected using a structured tool developed in an Open Data Kit and exported to Stata version 17.0 for cleaning and analysis. Descriptive statistics were used to summarize the data. Bivariable and multivariable logistic regression analyses were performed to identify factors associated with children’s dropout from measles vaccination. Adjusted odds ratio at a 95 % confidence interval was used to declare statistically significant associations.</div></div><div><h3>Results</h3><div>The overall magnitude of measles vaccination dropout was 42.5 % (95 % CI: 37.3, 47.6 %). Children with a birth order of 2–4 (AOR = 3.09, 95 % CI: 1.38, 6.94), and ≥ 5 (AOR = 4.25, 95 % CI: 1.90, 9.48), born to a merchant mother (AOR = 3.63, 95 % CI: 1.64, 8.04), and whose mothers/caregivers had a negative attitude towards vaccination (AOR = 3.82, 95 % CI: 2.18, 6.69) were more likely to dropout from measles vaccination. Children whose mothers attended at least primary level of education (AOR = 0.28, 95 % CI: 0.12, 0.68), whose fathers attended primary education and above (AOR = 0.25, 95 % CI: 0.08, 0.81), and children from middle-income families (AOR = 0.32, 95 % CI: 0.13, 0.79) were less likely to experience measles vaccination dropout.</div></div><div><h3>Conclusion</h3><div>The findings of this study highlight that two in five children dropped out of the measles vaccine program. Parental educational status, attitude towards vaccination, mother’s occupation, family income and child’s birth order were significantly associated with measles vaccination dropout. Future intervention strategies could focus on promoting a positive attitude towards the vaccine.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100267"},"PeriodicalIF":0.0,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144665827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}