Global pediatrics最新文献_第10页

“Neurodevelopmental outcome of a child with UPD(16)mat: A case report” "UPD(16)mat患儿的神经发育结果：病例报告"

Global pediatrics Pub Date : 2024-09-01 Epub Date: 2024-05-03 DOI: 10.1016/j.gpeds.2024.100179

Maria Novelli , Valeria Mammarella , Francesca Calandriello , Sara Temofonte , Marina Goldoni , Ilaria Macchiarulo , Paolo Versacci , Antonio Pizzuti , Jessica Petrilli , Carlo Di Brina , Barbara Caravale

{"title":"“Neurodevelopmental outcome of a child with UPD(16)mat: A case report”","authors":"Maria Novelli , Valeria Mammarella , Francesca Calandriello , Sara Temofonte , Marina Goldoni , Ilaria Macchiarulo , Paolo Versacci , Antonio Pizzuti , Jessica Petrilli , Carlo Di Brina , Barbara Caravale","doi":"10.1016/j.gpeds.2024.100179","DOIUrl":"https://doi.org/10.1016/j.gpeds.2024.100179","url":null,"abstract":"<div><h3>Objective</h3><p>UPD(16)mat is a rare genetic condition characterized by intrauterine growth deficiency and multiple congenital malformations. To the best of our knowledge, neurodevelopmental disorders have never been described in association with UPD(16)mat, nor a comprehensive neuropsychological profile of a UPD(16)mat child has never been delineated. We present a young patient diagnosed with UPD(16)mat, and provide clinical description, comprehensive neurodevelopmental, neuropsychological and neurological assessment.</p></div><div><h3>Method</h3><p>Neuropsychological examination included global neurodevelopment and intelligence scales, as well as specific trials for gross-motor, fine-motor and perceptual motor abilities, and language skills.</p></div><div><h3>Results</h3><p>The patient shows multiple congenital anomalies, including oesophageal atresia, mild bone alterations, hypospadias, persistent left superior vena cava. The neurodevelopmental evaluation demonstrates a speech disorder, signs of gross and fine motor skills difficulties, balance and visuo-motor deficit.</p></div><div><h3>Conclusion</h3><p>Evidence from this study indicates that UPD(16)mat may present neuropsychological and/or minor neurological abnormalities. Monitoring both the early and late neurodevelopmental outcomes during childhood is recommended for the chance of an early intervention.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100179"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000472/pdfft?md5=e8ef4729a354631ed3fd25c295dc4c44&pid=1-s2.0-S2667009724000472-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140901199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heat waves and pediatric emergency department febrile-related visits 热浪与儿科急诊室发热相关就诊率

Global pediatrics Pub Date : 2024-09-01 Epub Date: 2024-04-21 DOI: 10.1016/j.gpeds.2024.100178

Miguel Ángel Molina Gutiérrez , Belén Tortajada Hernández , Clara Díez-Picazo Garot , María Camacho Gil , María Bellido Gómez , Ferrán Campillo López

{"title":"Heat waves and pediatric emergency department febrile-related visits","authors":"Miguel Ángel Molina Gutiérrez , Belén Tortajada Hernández , Clara Díez-Picazo Garot , María Camacho Gil , María Bellido Gómez , Ferrán Campillo López","doi":"10.1016/j.gpeds.2024.100178","DOIUrl":"https://doi.org/10.1016/j.gpeds.2024.100178","url":null,"abstract":"<div><h3>Background</h3><p>In recent decades, we have observed an increase in ambient temperature due to the effects of climate change.</p></div><div><h3>Objective</h3><p>In this study, we aimed to determine whether there is a correlation between environmental temperature and urgent consultations of pediatric patients related to febrile processes.</p></div><div><h3>Research design and method</h3><p>We conducted an observational, retrospective, single-center study in the pediatric ED of the Hospital Universitario La Paz, Madrid, Spain. We analyzed visits to the ED for febrile processes during the last heat waves in Madrid.</p></div><div><h3>Results</h3><p>Between 2018 and 2022, seven heat waves were recorded in Madrid. A total of 3967 patients with fever as the main reason for consultation attended during this period. In two of the seven heat waves analyzed, febrile-related visits were higher during the heat alert. The first occurred between 6/11/2022 and 6/16/2022, with 345 febrile-related ED visits, 25.4% more than the previous days and 19.7% more than the following days. During this heat wave, we observed a positive correlation between the maximum temperature recorded and the number of visits to the ED for febrile processes (Rs=0.552; <em>p</em> = 0.018). During the heat wave between 09/07/2022 and 17/07/2022, 362 febrile-related ED visits were 3.1% more than the previous days and 24.9% more than the following days.</p></div><div><h3>Conclusion</h3><p>During recent heat waves in our city, we registered an increase in febrile-related visits compared with non-heat alert periods.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100178"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000460/pdfft?md5=d20af6c505ad42f08aaa9ca8dec18390&pid=1-s2.0-S2667009724000460-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140641187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Child bride and forced marriages: Legal aspects 童养媳和强迫婚姻：法律方面

Global pediatrics Pub Date : 2024-09-01 Epub Date: 2024-06-27 DOI: 10.1016/j.gpeds.2024.100208

Clara Pettoello-Mantovani

{"title":"Child bride and forced marriages: Legal aspects","authors":"Clara Pettoello-Mantovani","doi":"10.1016/j.gpeds.2024.100208","DOIUrl":"10.1016/j.gpeds.2024.100208","url":null,"abstract":"<div><p>The scourge of underage marriages and forced unions transcends borders, impacting individuals under 18 across diverse regions, cultures, and religious beliefs, albeit with varying degrees of prevalence. Currently, one in every five girls globally becomes a bride before turning 18, with a staggering one-third wed before reaching 15. These unions exact a profound toll on emotional and social development, often depriving girls of their right to education, familial connections, leisure, and thrusting them into adult roles, including involuntary motherhood. The denial of childhood, coupled with the grave physical and emotional toll of underage and coerced marriages, yields lasting ramifications on girls' health, prospects, and overall well-being, imperiling not just their lives but also those of their offspring and the collective future. Such marriages constitute a severe form of child abuse, exposing girls to diverse forms of physical violence with enduring repercussions. This commentary, aims to heighten awareness among main stakeholders entrusted with the welfare of minors, including legislators, healthcare professionals and local communities, regarding this issue and its lasting perils. Finally, it underscores the pivotal role pediatricians can play as advocates, actively engaging in programs aimed at monitoring and thwarting the adverse personal and societal repercussions engendered by these distressing phenomena among the under-18 demographic.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100208"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000769/pdfft?md5=9342f5f6791b9d2d01c10ec57ab107d6&pid=1-s2.0-S2667009724000769-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141731848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Shortage of essential pediatric medications puts children's health at risk. Results from a European Confederation of Primary Care Paediatricians (ECPCP) Survey 2023 儿科基本药物短缺危及儿童健康。欧洲初级保健儿科医生联合会 (ECPCP) 2023 年调查结果

Global pediatrics Pub Date : 2024-09-01 Epub Date: 2024-08-14 DOI: 10.1016/j.gpeds.2024.100224

Christine Magendie , Gottfried Huss , Laura Reali , Stephen Reingold

{"title":"Shortage of essential pediatric medications puts children's health at risk. Results from a European Confederation of Primary Care Paediatricians (ECPCP) Survey 2023","authors":"Christine Magendie , Gottfried Huss , Laura Reali , Stephen Reingold","doi":"10.1016/j.gpeds.2024.100224","DOIUrl":"10.1016/j.gpeds.2024.100224","url":null,"abstract":"<div><p>Unparalleled drug shortages during the winter of 2022/2023 had a profound impact on paediatric primary care across Europe. A survey conducted by the European Confederation of Primary Care Paediatricians (ECPCP) evaluated the availability of essential pediatric drugs and the resulting challenges. The survey was conducted between January and March 2023 and included responses from 640 paediatricians from 18 countries. The results of the survey indicated that there were substantial shortages, particularly of child friendly formulations of commonly prescribed medicines. Paediatricians in the survey feared that the use of less appropriate alternatives could potentially compromise the efficacy and safety of treatment. The survey findings highlight the urgent need for coordinated actions at multiple levels to ensure the availability of essential pediatric medications and safeguard children's health in future crises.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100224"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000927/pdfft?md5=8515c00c6812cd573b51e769f625473d&pid=1-s2.0-S2667009724000927-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142044621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunization, new viruses, and new vaccines 免疫、新病毒和新疫苗

Global pediatrics Pub Date : 2024-09-01 Epub Date: 2024-06-27 DOI: 10.1016/j.gpeds.2024.100211

Naveen Thacker , Vipin M Vashishtha , Sayali Lawate

{"title":"Immunization, new viruses, and new vaccines","authors":"Naveen Thacker , Vipin M Vashishtha , Sayali Lawate","doi":"10.1016/j.gpeds.2024.100211","DOIUrl":"https://doi.org/10.1016/j.gpeds.2024.100211","url":null,"abstract":"<div><p>A global outbreak of Coronavirus Disease 2019 (COVID-19) which is caused by a new virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has just occurred. An instance of an infectious virus that has been transmitted to humans and had a substantial effect on worldwide health and the economy is SARS-CoV-2. In the human population, besides SARS-CoV-2, numerous additional viruses have lately emerged or re-emerged. To accurately predict the hazards of emerging and re-emerging viral infections, close cooperation between the public health system and the scientific community is essential. Some of the reasons that may be related to the emergence and re-emergence of novel viruses include urbanization, alterations in the natural environment, globalization, and insufficient public health infrastructure.</p><p>Vaccines will aid in efficiently controlling the intense outbreaks caused by these emerging viruses. Nevertheless, the creation of novel vaccines encounters various obstacles, including tight deadlines for development and the ongoing evolution of viral variants. Notwithstanding, the difficulties encountered in vaccine development, recent progress in the vaccine development process has yielded a significant breakthrough in combating disease outbreaks. Recent advancements in immunology, genetics, and biotechnology have enabled the creation of several vaccines, including those for dengue, RSV, chikungunya, malaria, and most notably, COVID-19. These novel vaccinations protect a broad spectrum of viruses and other pathogenic microorganisms, including those that are challenging to control or have just emerged.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100211"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000794/pdfft?md5=2f03573901047b9e0ad3e587610844f1&pid=1-s2.0-S2667009724000794-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The accident prevention 事故预防

Global pediatrics Pub Date : 2024-09-01 Epub Date: 2024-06-06 DOI: 10.1016/j.gpeds.2024.100191

Aida Mujkić , Jasmina Šeremet Zebec

引用次数: 0

Neuroprotective treatment options for neonatal hypoxic-ischemic encephalopathy: Therapeutic hypothermia and beyond 新生儿缺氧缺血性脑病的神经保护治疗方案：治疗性低温及其他

Global pediatrics Pub Date : 2024-09-01 Epub Date: 2024-07-26 DOI: 10.1016/j.gpeds.2024.100223

Merih Cetinkaya

{"title":"Neuroprotective treatment options for neonatal hypoxic-ischemic encephalopathy: Therapeutic hypothermia and beyond","authors":"Merih Cetinkaya","doi":"10.1016/j.gpeds.2024.100223","DOIUrl":"10.1016/j.gpeds.2024.100223","url":null,"abstract":"<div><p>Hypoxic-ischemic encephalopathy (HIE) is the most common form of neonatal encephalopathy that develops due to perinatal asphyxia or ischemia in term and late-preterm infants. It is an important cause of significant neurological impairment and also mortality in newborns worldwide. The pathophysiology of HIE is multifactorial and involves complex cascades of cellular and biochemical events in the brain including excitotoxicity, oxidative stress, inflammation, and cell death, respectively. Therapeutic hypothermia (TH), is the only standard neuroprotective therapy for HIE and is associated with reduced composite outcome of death or major neurodevelopmental disability. However, although TH is beneficial, neonates with HIE still experience unacceptably high rate of devistating morbidities. Therefore, research for adjunctive therapies continue to further improve outcomes in infants with HIE. In this review, both TH and other promising adjunctive neuroprotective therapies are discussed for developing future treatment strategies.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100223"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000915/pdfft?md5=cdf0a71b1ff18024db042aa41d5e0a9e&pid=1-s2.0-S2667009724000915-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141839228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gene therapy for rare haematological and neurometabolic paediatric diseases 罕见血液病和神经代谢性儿科疾病的基因疗法

Global pediatrics Pub Date : 2024-09-01 Epub Date: 2024-06-09 DOI: 10.1016/j.gpeds.2024.100196

Vera Gallo , Alessandro Aiuti

{"title":"Gene therapy for rare haematological and neurometabolic paediatric diseases","authors":"Vera Gallo , Alessandro Aiuti","doi":"10.1016/j.gpeds.2024.100196","DOIUrl":"10.1016/j.gpeds.2024.100196","url":null,"abstract":"<div><p>Nowadays, gene therapy hast the potential to cure an increasingly greater number of monogenic inherited disorders with absent or limited treatment options, and radically change their natural history. Hematopoietic stem cells (HSCs) represent one of the preferred targets for gene therapy, as genetic modification of multipotent cells ensures a permanent correction of the progeny. Gene-corrected HSCs and their progeny can also be used as cell vehicles to deliver molecules into the circulation and tissues, including the central nervous system or the skeleton. Major successes of this approach have been achieved in the field of monogenic blood disorders and neurometabolic diseases and several medicinal products have recently reached the stage of marketing approval by the EMA based on safety and efficacy data collected over more than 10 years of clinical trials. Gene therapy for these severe pathologies offers undeniable advantages over the sole alternative therapy of allogeneic transplantation because it can be applied to every patient, even when no matched HLA donor is available, reducing mortality and complications related to allogeneic transplantation, such as graft-versus-host disease, graft rejection, organ toxicity, and infections. Additionally, in neurometabolic diseases, gene therapy allows supra-physiological expression of the transgene, consequently producing supra-normal levels of the missing enzyme, providing a greater clinical benefit compared to allogeneic transplantation. Despite these remarkable achievements, several challenges remain for HSPC gene therapy regarding access to treatment and its sustainability for the future.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100196"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000642/pdfft?md5=0ccc863d2c64a0cc399dfdb1a7a1ac1f&pid=1-s2.0-S2667009724000642-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141410977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urinary Incontinence in childhood 儿童尿失禁

Global pediatrics Pub Date : 2024-09-01 Epub Date: 2024-05-23 DOI: 10.1016/j.gpeds.2024.100187

L. Szabó

{"title":"Urinary Incontinence in childhood","authors":"L. Szabó","doi":"10.1016/j.gpeds.2024.100187","DOIUrl":"10.1016/j.gpeds.2024.100187","url":null,"abstract":"<div><p>In childhood, all forms of adult urinary incontinence occur, only the underlying causes and their distribution may be different.</p><p>Patients and Methods</p><p>5725 children (aged 0–18 years) underwent urodynamic examination in the Velkey László Child Health Center, Miskolc, and in the Heim Pál National Pediatric Institute, Budapest between 1986 and 2023.</p><p>Results: 675 children had urinary incontinence. 471/1335 children with nocturnal enuresis had non-monosymptomatic enuresis with urge incontinence. 115 children have dysfunctional voiding.</p><p>Videourodynamic study showed overactive bladder dysfunction in 31 %, neurogenic bladder dysfunction in 7 %, urine outflow obstruction in 3 %, and vaginal reflux in 2 % children.</p><p>Conclusion: The disorder of urinary retention and emptying occurs as a result of the disorder of the coordinated functioning of the bladder emptying muscle, the detrusor and the closing muscle group, the sphincter. Urge incontinence, overactive bladder function is the most common form of UI in childhood. Anamnesis and uroflow examination are sufficient to establish an accurate diagnosis. Unfortunately, anticholinergic medication is still the accepted treatment for children, with many side effects.</p><p>Incontinence after urination is most often caused by vaginal reflux, which can be easily detected with a video urodynamic examination.</p><p>Nocturnal enuresis is one of the most common problems in early childhood. Simple explanation, the bladder fills up at night, either because there is a lot of urine output at night, or because the bladder capacity is small. The next step is that the child does not wake up with a full bladder. He sleeps so deeply that he does not respond to the urge to urinate during sleep, and he wets the bed or wakes up and becomes a nocturnal urinates.</p><p>Most childhood urinary incontinence can be successfully treated and resolved in childhood.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100187"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000551/pdfft?md5=8c26ae920c3bef33d027eb1955ac7042&pid=1-s2.0-S2667009724000551-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors associated with feeding behavior in the early neonatal period focusing on early skin-to-skin contact and epidural analgesia: A prospective observational study at a single hospital in Japan 新生儿早期喂养行为的相关因素，重点关注早期皮肤接触和硬膜外镇痛：日本一家医院的前瞻性观察研究

Global pediatrics Pub Date : 2024-09-01 Epub Date: 2024-06-29 DOI: 10.1016/j.gpeds.2024.100216

Aya Tomita, Emi Tahara-Sasagawa, Kaori Yonezawa, Yuriko Usui, Megumi Haruna

{"title":"Factors associated with feeding behavior in the early neonatal period focusing on early skin-to-skin contact and epidural analgesia: A prospective observational study at a single hospital in Japan","authors":"Aya Tomita, Emi Tahara-Sasagawa, Kaori Yonezawa, Yuriko Usui, Megumi Haruna","doi":"10.1016/j.gpeds.2024.100216","DOIUrl":"https://doi.org/10.1016/j.gpeds.2024.100216","url":null,"abstract":"<div><h3>Background</h3><p>The feeding behavior of newborns is influenced by the conditions of both the mother and newborn before and after birth.</p></div><div><h3>Aims</h3><p>This study aimed to investigate the factors associated with newborn feeding behavior, focusing on skin-to-skin contact (SSC) as a promoting factor and epidural analgesia as an inhibiting factor, using the Japanese version of the Infant Breastfeeding Assessment Tool (IBFAT).</p></div><div><h3>Study Design</h3><p>Prospective observational study conducted in Japan.</p></div><div><h3>Participants</h3><p>A total of 176 pairs of healthy mothers and their healthy full-term newborns.</p></div><div><h3>Outcome Measures</h3><p>The primary outcome was newborn feeding behaviors measured using the Japanese version of IBFAT within about one day of birth. Stepwise multiple regression analysis was performed to explore the relationship between IBFAT scores and variables that might influence newborn feeding behavior.</p></div><div><h3>Results</h3><p>Multiple regression analysis revealed that lower IBFAT scores were associated with a higher dose of epidural fentanyl (β = −0.40), and higher IBFAT scores were associated with a longer duration of SSC (β = 0.26), even after adjusting for gestational weeks and Apgar scores. The dose and duration of synthetic oxytocin administration were not associated with IBFAT scores in the multivariate analysis.</p></div><div><h3>Conclusions</h3><p>Our study showed a dose-dependent relationship between fentanyl and SSC, suggesting that consistently implementing SSC for the maximum duration possible may enhance newborn feeding behaviors, which are reduced by fentanyl administration.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100216"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667009724000848/pdfft?md5=4c0a74a3954e774b0df7363ff16f8028&pid=1-s2.0-S2667009724000848-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141541239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0