Global pediatrics最新文献

{"title":"Knowledge of human papillomavirus vaccine as a determinant of uptake among guardians of adolescent girls: A single hospital in nairobi, kenya","authors":"Irene Nzisa ,&nbsp;Rose Kamenwa ,&nbsp;James Orwa ,&nbsp;Pauline Samia","doi":"10.1016/j.gpeds.2025.100249","DOIUrl":"10.1016/j.gpeds.2025.100249","url":null,"abstract":"<div><div>Cervical cancer is one of the most common preventable cancers, causing significant morbidity and mortality in women, especially in Sub-Saharan Africa. Despite the availability of free HPV vaccination, the proportion of adolescent girls vaccinated against HPV remains low.</div></div><div><h3>Methods</h3><div>Our aim was to identify knowledge and factors influencing HPV vaccine uptake among parents of adolescent girls and to determine the proportion of adolescent girls vaccinated within three months after the provision of additional information on cervical cancer and HPV vaccine. We undertook a mixed methods study design, with an initial cross-sectional part followed by a prospective cohort study among guardians of adolescent girls aged 9–18 years attending Aga Khan University Hospital Nairobi, Kenya. Guardians of adolescent girls who had not received the HPV vaccine were provided with standardized written information regarding cervical cancer, HPV vaccine availability, and utility. Guardians were then contacted three months later to evaluate subsequent HPV vaccine uptake.</div></div><div><h3>Results</h3><div>A total of 432 guardians participated in the study. The majority (94.7 %) knew about cervical cancer, 84.9 % of them had heard about the HPV vaccine, and 48 % were aware of the free vaccination campaign. Only 13.2 % (<em>n</em> = 57) of the participants reported that their daughters had been vaccinated prior to this study. Factors associated with vaccine uptake included the level of knowledge (<em>p</em> ≤ 0.001) and the age of the parents (<em>p</em> = 0.030). Reasons commonly cited for not taking the vaccine included lack of information (73 %), lack of awareness (45 %), safety concerns (13 %) and concerns about affordability (7 %). A total of 306 participants were followed up three months later, and 9.2 % (<em>n</em> = 28) of them reported that their daughters had been vaccinated.</div></div><div><h3>Conclusion</h3><div>The knowledge of the HPV vaccine was good at 67 %. However, uptake of the HPV vaccine was low in this study population despite providing them with additional information about the HPV vaccine. Higher levels of parental knowledge and older age were associated with a greater likelihood of HPV vaccine uptake. Innovative methods to reassure hesitant parents about HPV vaccination for their daughters are urgently needed in the Kenyan general population.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"12 ","pages":"Article 100249"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonatal resuscitation skill among health care providers in Eastern Africa: A systematic review and meta-analysis","authors":"Addis Eyeberu,&nbsp;Elias Yadeta,&nbsp;Haymanot Mezmur,&nbsp;Aboma Motuma,&nbsp;Adera Debella","doi":"10.1016/j.gpeds.2025.100248","DOIUrl":"10.1016/j.gpeds.2025.100248","url":null,"abstract":"<div><h3>Background</h3><div>Neonatal resuscitation skills involve providing ventilation, clearing airways, performing chest compressions, and administering necessary interventions to stabilize newborns in distress. Although basic neonatal resuscitation has been shown to improve newborn survival rates, asphyxia-related neonatal mortality remains high. This is partly due to inadequate skills among healthcare providers, who also exhibit varying expertise in newborn resuscitation across the region. Therefore, this study aimed to assess the pooled level of neonatal resuscitation skills among healthcare providers and identify associated factors.</div></div><div><h3>Methods</h3><div>Articles were searched from major databases. Data were analyzed using Stata version 18 statistical software. The overall estimates with a 95 % confidence interval were estimated using a random effect model.</div></div><div><h3>Results</h3><div>A total of 7038 healthcare providers were included in this study. The overall pooled result revealed that the level of neonatal resuscitation skills among healthcare providers in Eastern Africa was 48 % [95 % CI: 34–62]. The highest and lowest pooled level of neonatal resuscitation skills was observed among studies conducted in Ethiopia 57 % (95 % CI: 38–74) and Somalia 14 % (95 % CI: 8–22) respectively. Trained in neonatal resuscitation (OR = 1.87, 95 % CI: 1.26, 2.48), age above 35 (OR = 0.16, 95 % CI:0.14, 0.42), and having good knowledge (OR = 2.08, 95 % CI: 1.31, 2.86) were significantly associated with neonatal resuscitation skill.</div></div><div><h3>Conclusions</h3><div>The level of neonatal resuscitation skills in Eastern Africa is generally low. Factors such as receiving training in neonatal resuscitation, possessing adequate knowledge, and being over the age of 35 were significantly associated with neonatal resuscitation skills. Therefore, strengthening both short-term and long-term training programs, along with regular updates on neonatal resuscitation protocols, can enhance healthcare providers' skills in this critical area.</div></div><div><h3>Implications for Clinical Skill</h3><div>Identifying and addressing skill gaps in neonatal resuscitation can enhance clinical competency among healthcare providers, leading to improved neonatal survival rates. Additionally, this study can inform the development of training programs, influence policies, and foster quality improvement initiatives in healthcare facilities.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100248"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143580642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors of preterm birth in greater Accra regional hospital, ridge","authors":"Immanuel Adom-Miah ,&nbsp;Williams Ampadu Oduro ,&nbsp;David Boateng Appiah ,&nbsp;Theodocea Nortey","doi":"10.1016/j.gpeds.2025.100247","DOIUrl":"10.1016/j.gpeds.2025.100247","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to investigate the sociodemographic, psychological, cultural, environmental, and occupational risk factors associated with preterm birth at the Greater Accra Regional Hospital.</div></div><div><h3>Study Design</h3><div>A case-control study.</div></div><div><h3>Methods</h3><div>The study employed a case-control design and used the Chi-square test to assess associations between various risk factors and preterm birth. Sociodemographic, psychological, cultural, environmental, and occupational factors were examined to determine their relationship with preterm birth.</div></div><div><h3>Results</h3><div>The findings revealed a significant association between depression and preterm birth, with a Chi-square value of 12.115 and a p-value of 0.001. Moderate exercise was also associated with preterm birth, showing a significant relationship (p-value of 0.039). However, the mothers’ occupation, including posture at work, hours spent in a specific position, and exposure to heat, chemicals, dust, or smoke, did not demonstrate significant associations with preterm birth.</div></div><div><h3>Conclusions</h3><div>The study emphasizes the need for enhanced maternal and child healthcare efforts in the country and underscores the importance of public education, particularly regarding the role of partner support in reducing the risk of preterm birth.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100247"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143561890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of essential newborn care for institutional births in Bangladesh: Findings from the 2019 MICS Survey","authors":"Syeda Sumaiya Efa ,&nbsp;Syed Nafi Mahdee ,&nbsp;Md Fuad Al Fidah","doi":"10.1016/j.gpeds.2025.100246","DOIUrl":"10.1016/j.gpeds.2025.100246","url":null,"abstract":"<div><h3>Background</h3><div>Millions of newborns die globally during the neonatal period. Essential newborn care (ENC) is designed to lower neonatal morbidity and mortality. The current study investigated the association between sociodemographic, antenatal, and delivery care factors that may impact ENC practices for institutional birth in Bangladesh.</div></div><div><h3>Methods</h3><div>The current study utilized publicly available, nationally representative data. A total of 404 participants were considered for analysis. A logistic regression model was developed, with significant variables identified by chi-square tests. A p-value &lt;0.05 was considered statistically significant (α=0.05).</div></div><div><h3>Results</h3><div>Almost half of the participants were &lt;20 years old (241, 59.7 %), half had secondary level education (205, 50.7 %), and one-third were from the poorest wealth quintile (123, 30.4 %). The prevalence of proper ENC was 57 (14.1 %). In 383 (94.8 %) cases, instruments were utilized to cut the umbilical cord, with 271 (67.1 %) showing no application of substances to the cord stump. Following birth, 396 (98.0 %) newborns underwent drying, while 294 (72.8 %) were immediately wrapped. Delayed bathing was observed in 131 (32.4 %) cases, with 359 (89.9 %) initiating breastfeeding. Proper ENC was associated with assistance by skilled birth attendant (SBA) (<em>p</em> = 0.004) and residence (<em>p</em> = 0.047). Higher odds of proper ENC were found among those who received assistance by SBA (AOR: 2.39; 95 % CI: 1.32–4.32; <em>p</em> = 0.004) and belonging to the middle class (AOR: 2.90; 95 % CI: 1.26–6.68; p-value=0.012).</div></div><div><h3>Conclusion</h3><div>Proper ENC in institutional birth is not widely practiced in Bangladesh. Targeted health promotional activities and policies, especially assistance by a SBA and raising awareness among mothers of the poorest families, can help to improve ENC practices during institutional birth.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100246"},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The present and the future of point-of-care ultrasound in Pediatric Care","authors":"G. Bausani ,&nbsp;AMC Musolino ,&nbsp;L. Reali","doi":"10.1016/j.gpeds.2025.100245","DOIUrl":"10.1016/j.gpeds.2025.100245","url":null,"abstract":"","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100245"},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact and frequency of misdiagnosis of appendicitis in pediatric patients with gastroenteritis in a developing country","authors":"Pastor Escárcega-Fujigaki ,&nbsp;Guillermo Hernández-Peredo-Rezk ,&nbsp;Gerardo Alonso-Acosta ,&nbsp;Keren-Hapuc Vargas-Amador","doi":"10.1016/j.gpeds.2025.100244","DOIUrl":"10.1016/j.gpeds.2025.100244","url":null,"abstract":"<div><h3>Aim</h3><div>Appendicitis manifests with atypical symptoms in a large percentage of patients, leading to diagnostic errors that delay diagnosis. This study aimed to evaluate the impact and frequency of appendicitis being incorrectly diagnosed as gastroenteritis in a developing country.</div></div><div><h3>Methods</h3><div>This prospective, comparative study included 207 pediatric patients with appendicitis divided into two groups: group A, with 117 (56.5 %) patients with diagnostic errors, and group B, with 90 (43.4 %) patients without diagnostic errors. Clinical, laboratory, and imaging data were compared using the Mann–Whitney tests, odds ratio (OR), and 95 % confidence interval (CI) with statistical significance set at <em>p</em>-value &lt;0.05.</div></div><div><h3>Results</h3><div>The diagnosis was confused with gastroenteritis in 66 (56.4 %) patients, causing a delay in surgical management, which was statistically significant (OR: 2.25; 95 % CI: 1.23–4.09; <em>p</em> &lt; 0.005) when compared with group B. The second most common cause of confusion was colitis, which was observed in 40 (34.2 %) patients. Group A had a large number of perforated appendicitis cases (OR: 3.22; 95 % CI: 1.81–5.72; <em>p</em> &lt; 0.01), with more days till oral administration initiation (OR: 3.68; 95 % CI: 1.32–10.27; <em>p</em> &lt; 0.01) and longer hospital stays (OR: 6.83; 95 % CI: 1.85–25.11; <em>p</em> &lt; 0.01). Furthermore, general practitioners more frequently had diagnostic errors than pediatricians (OR: 0.17; 95 % CI: 0.07–0.43; <em>p</em> &lt; 0.01).</div></div><div><h3>Conclusions</h3><div>The diagnosis of appendicitis was confused with gastroenteritis or colitis in majority of pediatric patients. Practitioners should be aware of the possibility of appendicitis in patients presenting with abdominal pain, diarrhea, or fever.</div></div><div><h3>Level of Evidence</h3><div>III</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100244"},"PeriodicalIF":0.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness evaluation of neonatal emergency transport organization in Italy","authors":"Carlo Bellini ,&nbsp;Maurizio Gente ,&nbsp;Diego Minghetti ,&nbsp;Luca A. Ramenghi","doi":"10.1016/j.gpeds.2025.100243","DOIUrl":"10.1016/j.gpeds.2025.100243","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to evaluate the cost-effectiveness of the Italian Neonatal Emergency Transport Service (NETS), to analyse its current organisation and to identify potential financial benefits from improvements.</div></div><div><h3>Methods</h3><div>Using data from the 2023 national NETS survey conducted by the Italian Society of Neonatology, regional cost-effectiveness of operating the system were calculated. These were compared with ideal costs for on-call and dedicated NETS models, based on a previously established methodology.</div></div><div><h3>Results</h3><div>The total cost of operating NETS in Italy was €32,785,650. Of this, €24,964,050 was associated with services organised according to the on-call model, while €7,821,600 was associated with dedicated services. The cost per transport varied considerably between regions. The national median cost for on-call services was €7,386 (ranging from €1,809 to €76,209), while the national median cost for dedicated services was €2,421 (ranging from €2,073 to €2,770). The actual total cost could be reduced to the ideal cost of €15,304,308, with the ideal cost per individual transport being €2,450 for on-call services and €2,250 for dedicated services (compared to the current medians of €7,386 and €2,421, respectively).</div></div><div><h3>Conclusions</h3><div>The study concluded that the Italian NETS organisation is expensive and unsustainable due to limited financial resources, and requires a complete overhaul. The implementation of a more cost-effective 'hub-and-spoke' NETS network system could significantly improve financial sustainability. The findings suggest that improvements to the NETS organisation are needed not only in Italy, but potentially across Europe.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100243"},"PeriodicalIF":0.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying birth asphyxia risk factors: Case-control study of new-borns delivered at public health institutions in Gedeo Zone, Ethiopia","authors":"Getachew Mergia ,&nbsp;Getnet Melaku","doi":"10.1016/j.gpeds.2024.100242","DOIUrl":"10.1016/j.gpeds.2024.100242","url":null,"abstract":"<div><h3>Background</h3><div>Birth asphyxia, a global health issue causing insufficient oxygen supply, causes around 900,000 annual deaths worldwide. This study aimed to identify risk factors for birth asphyxia in new-borns delivered at public health institutions, reducing neonatal mortality.</div></div><div><h3>Methods</h3><div>This study used an institution-based, unmatched case-control study design with a total of 354 new-borns. We used descriptive statistics and a logistic regression model to thoroughly evaluate the data and find characteristics linked with birth asphyxia. The data were given using adjusted odds ratios with 95 % confidence intervals to ensure a thorough understanding of the risk variables involved.</div></div><div><h3>Result</h3><div>The study included 119 cases and 235 controls, with a median maternal age of 27 years. Factors contributing to birth asphyxia included mode of delivery and amniotic fluid color, with caesarean section (AOR: 4.706, 95 % CI: 2.132–10.386) and unclear amniotic fluid (AOR: 4.991, 95 % CI: 2.609–9.547) significantly increasing the odds of asphyxia.</div></div><div><h3>Conclusion</h3><div>This study identified significant factors contributing to birth asphyxia, including Caesarean section mode of delivery and unclear amniotic fluid color. These findings highlight the importance of monitoring and managing delivery methods and amniotic fluid status to reduce the risk of birth asphyxia.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100242"},"PeriodicalIF":0.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143094132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Newborn birth weight and its associated risk factors in Somalia using Somalia health and demographic survey","authors":"Denekew Bitew Belay ,&nbsp;Nigussie Adam Birhan ,&nbsp;Mahad Ibrahim Ali ,&nbsp;Ding-Geng Chen","doi":"10.1016/j.gpeds.2024.100241","DOIUrl":"10.1016/j.gpeds.2024.100241","url":null,"abstract":"<div><h3>Background</h3><div>Low birth weight is the result of fetal growth and it is a strong sign of infant morbidity and mortality. In sub-Saharan Africa, the number of low birth weight live births is estimated to have increased from 4.4 million in 2000 to 5 million in 2015. Low birth weight is a strong indicator of multifaceted public health problems, including unfavorable socio-demographic conditions, chronic illness, and poor health care during pregnancy. The aim of this study was to assess the prevalence and risk factors of newborn birth weight in Somalia.</div></div><div><h3>Methods</h3><div>The data used for this study were obtained from the 2020 Somalia Health and Demographic Survey. A sample of 7462 newborn with their birth weight within five years preceding the survey was included. The newborns’ birth weight; which is first categorized in to three: low birth weight (&lt;2.5 kg), normal birth weight (2.5–4 kg) and high birth weight (&gt;4 kg), was considered as a response variable. The analysis was carried out using ordinal logistic regression and adjusted odds ratio with 95 % confidence interval and <em>p</em>-value &lt;0.05 was used to declare statistical significance.</div></div><div><h3>Results</h3><div>From the total of 7462 newborns include in the study, 1196 (16.03 %), 5304(71.08 %) and 962 (12.89 %) were born with low birth weight, normal birth weight and high birth weight, respectively. Maternal age (AOR = 1.48; 95 %CI: 1.12–1.956), having Antenatal care (ANC) visit (AOR = 1.24; 95 %CI: 1.09–1.41), gestational age <span><math><mo>≥</mo></math></span>37 weeks (AOR = 2.02; 95 % CI: 1.34–3.03), rich wealth index family (AOR = 1.46; 95 %CI: 1.29–1.65) and mother with secondary/higher educational level (AOR = 1.51; 95 %CI: 1.19–1.92) as well as place of residence were significantly associated with higher birth weight.</div></div><div><h3>Conclusion</h3><div>The results of this study showed that birth weight is significantly associated with mother age, ANC visit, mother educational level, wealth index, residence, and gestational age at birth. Significantly large proportions of newborn babies are born with low-birth weight and this might be duet to many factors. Since low birth weight is a strong indicator of multifaceted public health problem, the governmental and non- governmental organizations working on maternal health should focus on alleviating this public health burden by giving special attention for antenatal care utilization coverage and improve other maternal health.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100241"},"PeriodicalIF":0.0,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of surgical treatment on neonatal management in extremely low birth weight infants: Single-center retrospective study","authors":"Seiichiro Inoue,&nbsp;Yuki Muta,&nbsp;Yuta Takeuchi,&nbsp;Kohei Kawaguchi,&nbsp;Akio Odaka","doi":"10.1016/j.gpeds.2024.100240","DOIUrl":"10.1016/j.gpeds.2024.100240","url":null,"abstract":"<div><h3>Background</h3><div>Few studies have examined the details of extremely low birth weight (ELBW) infants (i.e., infants with a birth weight &lt; 1000 g) on neonatal intensive care units (NICUs) who require surgical treatment. Therefore, we analyzed mortality, morbidity, and clinical variables in ELBW infants who received surgical treatments at our center from 2009 to 2022.</div></div><div><h3>Methods</h3><div>All ELBW infants were included who received surgical treatment at our NICU from January 2009 to December 2022. We compared data from infants treated in the early (2009–2015) and late (2016–2022) periods and investigated trends in mortality, morbidity, and clinical variables.</div></div><div><h3>Results</h3><div>A total of 678 ELBW infants were admitted and cared at our neonatal center and 56 ELBW infants were received surgical treatment. The number of patients who received surgical treatment increased in the late period (10.4 % (36/345)) compared to the early period (6.33 % (20/316)) (early vs late period: <em>p</em> = 0.0398). The indications for surgery were expanded in late period compared to early periods. In the late period, the survival rate was higher (63.5 vs 75.0 %: early vs late period). No statistical difference was observed between the early and late period in the duration of the NICU stay. However, the duration of NICU stay in died patients were shorter compared to the survived patients (median (lower -upper quartiles):196.5 (166.75–261.25 vs 75.0 (49.0–183.5): early vs late period). The total number of surgical treatments which each patient received were higher in survived cases (median (lower -upper quartiles): 2.0 (2.0–4.0) vs 1.0 (1.0–2.0): survived vs died cases: <em>p</em> = 0.013).</div></div><div><h3>Conclusions</h3><div>Recent advances in NICU care have expanded the indications for surgical treatment in ELBW infants. Survival rates appear to have improved. In more recent years, patients have increasingly undergone multi-step surgical treatment, which we consider to be a result of the improved the systemic status of infants in perioperative period.</div></div><div><h3>Level of evidence</h3><div>3</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"11 ","pages":"Article 100240"},"PeriodicalIF":0.0,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}