Global pediatricsPub Date : 2025-08-15DOI: 10.1016/j.gpeds.2025.100285
Clara Pettoello-Mantovani , Margherita Zona , Francesca Scaltrito , Ignazio Cammisa , Ida Giardino , Pietro Ferrara
{"title":"International legal implications for children in conflict zones","authors":"Clara Pettoello-Mantovani , Margherita Zona , Francesca Scaltrito , Ignazio Cammisa , Ida Giardino , Pietro Ferrara","doi":"10.1016/j.gpeds.2025.100285","DOIUrl":"10.1016/j.gpeds.2025.100285","url":null,"abstract":"<div><div>This article examines the unique vulnerability of children in armed conflict, emphasizing the interplay between their developmental stage, inherent dependency, and evolving legal status. It explores the international legal framework for child protection, which integrates International Humanitarian Law, International Human Rights Law, and International Criminal Law to mitigate the impacts of conflict and ensure accountability for violations. Despite the existence of robust legal instruments, a persistent gap remains between legal norms and their effective implementation, resulting in ongoing harm to children. The article highlights how international law not only prohibits acts such as killing, maiming, and attacks on schools and hospitals but also mandates obligations for recovery, reintegration, and access to health and education—implicitly addressing the psycho-physical harm children endure. Arguing that legal understanding must extend beyond legal professionals to include healthcare providers, the article calls for interdisciplinary collaboration to protect children more effectively. It concludes by advocating for the integration of Mental Health and Psychosocial Support (MHPSS) as an explicit and adequately resourced component of the right to health in humanitarian responses, to address the full spectrum of children's needs in conflict settings.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"14 ","pages":"Article 100285"},"PeriodicalIF":0.0,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144887497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global pediatricsPub Date : 2025-08-14DOI: 10.1016/j.gpeds.2025.100284
Josiane G Luiz , Évelim Leal de Freitas Dantas Gomes , Manoella Cavalcante de Andrade , Dirceu Costa
{"title":"Analysis of the motor proficiency and physical capacity of asthmatic children and adolescents: A cross-sectional study","authors":"Josiane G Luiz , Évelim Leal de Freitas Dantas Gomes , Manoella Cavalcante de Andrade , Dirceu Costa","doi":"10.1016/j.gpeds.2025.100284","DOIUrl":"10.1016/j.gpeds.2025.100284","url":null,"abstract":"<div><h3>Background</h3><div>Exercise restrictions due to asthma are associated with a sedentary lifestyle and reduced physical activity. Based on the limited data available in the literature, improvements in motor proficiency among individuals with respiratory diseases may be related to increased physical activity and better performance in activities of daily living. Therefore, the aim of this study was to evaluate motor proficiency and its association with aerobic capacity in children and adolescents with asthma.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted. Motor proficiency was evaluated using the Movement Assessment Battery for Children – 2nd edition (MABC-2). Aerobic capacity was assessed using the Modified Shuttle Walk Test (MSWT). Asthma control was determined using the Asthma Control Questionnaire (ACQ6).</div></div><div><h3>Results</h3><div>Fifty participants not engaged in regular physical activity (25 with asthma and 25 controls) were evaluated. The mean age was 7.7 ± 2.65 years in the asthma group (AG) and 10.9 ± 3.89 years in the control group (CG). Both groups performed below predicted values in the MSWT (58.7 ± 21.3 % AG and 66.8 ± 29.2 % CG). The AG performed significantly worse than the CG on the aiming and catching subscale of the MABC-2 (15.4 ± 5.23 and 20.1 ± 7.06, <em>p</em> = 0.01, respectively). Moreover, a moderate negative correlation was found between manual dexterity and asthma control (<em>r</em> = -0.51, <em>p</em> = 0.02). Each 9.79-point increase in the MABC-2 manual dexterity subscale was associated with a 1.72-point reduction in the ACQ6.</div></div><div><h3>Conclusions</h3><div>Low aerobic capacity appears to negatively impact balance, and poor asthma control appears to negatively affect manual dexterity in the AG. Moreover, the AG had worse performance in aiming and catching compared to the CG.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"14 ","pages":"Article 100284"},"PeriodicalIF":0.0,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144907029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The use of photography for qualitative data collection with adolescent mothers: a scoping review","authors":"Daniela de Castro Barbosa Leonello , Giovanna Ushirobira Souza , Rhyquelle Rhibna Neris , Giovanna Cristina Machado Kayzuka , Marina Prado de Souza , Adriana Moraes Leite","doi":"10.1016/j.gpeds.2025.100283","DOIUrl":"10.1016/j.gpeds.2025.100283","url":null,"abstract":"<div><h3>Introduction</h3><div>Photography has been increasingly explored in data collection processes, as it enriches the process and allows the interviewee to take on the role of protagonist [1]. Among the methods that use images, <em>Photovoice</em> and Photo-Elicitation stand out in qualitative research [2]. The objective of this research was to map the development of Photo-Elicitation and <em>Photovoice</em> methods with adolescent mothers as data collection techniques.</div></div><div><h3>Methods</h3><div>A scoping review was conducted from August to October 2024. The guiding question formulated was: \"How have Photo-Elicitation and <em>Photovoice</em> been developed with adolescent mothers as a data collection method?\". The search strategy included LILACS, PubMed, CINAHL, and <em>Web of Science</em>.</div></div><div><h3>Results</h3><div>A total of 46 articles were found, mostly published in English. Ten were selected after full-text reading.</div></div><div><h3>Conclusion</h3><div>The literature converges in considering Photo-Elicitation and <em>Photovoice</em> as visual and interactive resources that facilitate the communication of adolescent mothers' experiences.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"14 ","pages":"Article 100283"},"PeriodicalIF":0.0,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144860722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global pediatricsPub Date : 2025-08-06DOI: 10.1016/j.gpeds.2025.100282
Raymen R. Assaf , Theodore Heyming , Tricia Morphew , Kellie Bacon , Shelby Shelton , Jason A. Douglas
{"title":"Food and housing insecurity, adverse childhood experiences, and pediatric emergency department use","authors":"Raymen R. Assaf , Theodore Heyming , Tricia Morphew , Kellie Bacon , Shelby Shelton , Jason A. Douglas","doi":"10.1016/j.gpeds.2025.100282","DOIUrl":"10.1016/j.gpeds.2025.100282","url":null,"abstract":"<div><h3>Objective</h3><div>To describe the relationship between neighborhood-level <em>repression-adverse childhood experiences (ACEs)</em> (family member incarceration, community violence, discrimination), food and housing insecurity, and pediatric emergency department (ED) utilization.</div></div><div><h3>Methods</h3><div>The measured exposures were food/housing insecurity, <em>repression-ACEs</em>, and childhood opportunity index (COI 3.0) based on caregiver/patient surveys and home address. The primary outcome was ED visits 12 months before and after the ED index visit. Multivariable regression models examined associations between the exposures and annual ED visit rates per 100 patients, adjusting for potential confounders.</div></div><div><h3>Results</h3><div>From March 2021 - May 2023 6228 patients (range 0–22 years) had an index ED visit. 64.9 % were Hispanic, 7.0 % Asian, 1.9 % Black, 7.0 % Other/multiple races, and 19.1 % White. Of the participants, 11.6 % had a <em>repression-ACE</em>; 22.3 % food or housing insecurity, and average COI was moderate (53.3, SD = 23.8). Food and housing insecurity were higher among Black (29.0 %) and Hispanic (26.3 %) participants (<em>p</em> < 0.001). Very low to moderate COI was highest in Black (51.3 %) and Hispanic (77.4 %) participants (<em>p</em> < 0.001). Black participants reported the highest <em>repression-ACEs</em> (25.6 %, <em>p</em> < 0.001). In univariate analyses, food insecurity (RR = 1.12, <em>p</em> = 0.07) and housing insecurity (RR = 1.13, <em>p</em> = 0.04) increased the ED visit rate. Experiencing discrimination increased this rate by 27 %, (RR = 1.27, <em>p</em> = 0.02). The effect of violence exposure (<em>p</em> = 0.03) and family member incarceration (<em>p</em> = 0.07) on ED visit rate varied across racial groups.</div></div><div><h3>Conclusions</h3><div><em>Repression-ACEs</em> interact with race and ethnicity and social inequities (food/housing insecurity, COI) in shaping ED utilization. Impacts of ACEs on children’s health continue to shape inequities in pediatrics while defining areas for action.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100282"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144829168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global pediatricsPub Date : 2025-08-06DOI: 10.1016/j.gpeds.2025.100280
Jayalaxmi Shripati Aihole
{"title":"Neonatal umbilical hernia: A simple noninvasive technique","authors":"Jayalaxmi Shripati Aihole","doi":"10.1016/j.gpeds.2025.100280","DOIUrl":"10.1016/j.gpeds.2025.100280","url":null,"abstract":"<div><h3>Background</h3><div>A congenital umbilical hernia is a common anomaly seen at birth or during infancy, as a small or large umbilical bulge or swelling due to herniation of the bowel or omentum, mostly requiring medical attention. If umbilical fascial ring fails to close and obliterate after the separation of umbilical cord soon after birth, will be clinically presenting as umbilical hernia. Though spontaneous resolution of umbilical hernia is established fact, but however, duration of it, is still a matter of speculation and what should be done during this waiting period: twiddling the thumbs? and how to avoid surgical interventions or morbidities.</div></div><div><h3>Aim and methods</h3><div>Hence author proposes here a conservative, non-invasive management technique by mother herself to help to heal her baby from this anomaly during this watchful expectancy period to avoid fatalities.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100280"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144809608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global pediatricsPub Date : 2025-08-05DOI: 10.1016/j.gpeds.2025.100271
Qiong Le , Hong Lan , Meng-yun Hu , Li-fen Wu , Lin Wang , Shuang Wang , Jing Tao , Hong-ping Wang
{"title":"Family music therapy combined with oral motor intervention in preterm infants: A randomized controlled trial on feeding competence and parental mental health","authors":"Qiong Le , Hong Lan , Meng-yun Hu , Li-fen Wu , Lin Wang , Shuang Wang , Jing Tao , Hong-ping Wang","doi":"10.1016/j.gpeds.2025.100271","DOIUrl":"10.1016/j.gpeds.2025.100271","url":null,"abstract":"<div><h3>Objective</h3><div>The study aimed to evaluate the combined effects of family music therapy and oral motor intervention on oral feeding outcomes, oral motor function, and parental anxiety and depression in preterm infants, with the goal of providing new effective strategies for preterm infants’ feeding.</div></div><div><h3>Design</h3><div>This was a randomized controlled trial.</div></div><div><h3>Setting and Participants</h3><div>A total of 130 preterm infants from the neonatal ward were enrolled and randomly assigned to a control group and a study group in a 1:1 ratio using a computer-generated random sequence.</div></div><div><h3>Methods</h3><div>The control group received standard neonatal care and oral motor intervention, while the study group additionally received family music therapy. The primary outcome measures included oral feeding outcomes, oral motor function scores, and parental anxiety and depression scores.</div></div><div><h3>Results</h3><div>On the 7th day, statistically significant differences in normal morphology scores were observed between the two groups (<em>P</em> < 0.05). On the 14th day, significant differences were noted in the Oral Mobility Scale scores (<em>P</em> < 0.05). The study group had shorter total oral feeding transition time, nasogastric tube indwelling time, and hospital stay. There were no significant differences in complications between the two groups (<em>P</em> > 0.05). Post-intervention, parental anxiety and depression scores were significantly lower in the study group (<em>P</em> < 0.05).</div></div><div><h3>Conclusions</h3><div>The findings of this study suggest that combining family music therapy with oral motor intervention improved oral motor function, accelerated the feeding process in preterm infants, and reduced parental anxiety and depression.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"14 ","pages":"Article 100271"},"PeriodicalIF":0.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145095632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global pediatricsPub Date : 2025-08-05DOI: 10.1016/j.gpeds.2025.100281
Devin Neumann, Logan Nauts, Jason Odisho, Alex Park, Kaylynn Moschke, Angela Sasaki Cole, Clark Brady, Anna Coleman
{"title":"Developmental health changes following youth and adolescent excessive electronic media exposure: a systematic review","authors":"Devin Neumann, Logan Nauts, Jason Odisho, Alex Park, Kaylynn Moschke, Angela Sasaki Cole, Clark Brady, Anna Coleman","doi":"10.1016/j.gpeds.2025.100281","DOIUrl":"10.1016/j.gpeds.2025.100281","url":null,"abstract":"<div><div>Screen use, the use of a digital media device for entertainment purposes, has been increasing exponentially throughout the world over the last ten years. As children are being exposed to screens at younger ages, studies are being conducted to determine if and how these screens act as a benefit or detriment to development. The goal of this systematic review was to evaluate the current literature regarding the link between excessive screen use on the development of children and adolescents worldwide. Specifically, this review examined how screens affect multiple aspects of development, including neurological development, social development, motor development, and language development. A search of relevant terms was conducted from three different databases, and articles published between 2014 and 2024 were included. Studies demonstrated that excessive screen use is correlated with poorer outcomes in various aspects of development, and these effects are found to be more significant in younger children. However, some articles mentioned positive outcomes of using specific <em>types</em> of media (i.e., cell phone use, television, videogames), while some articles mentioned that other types of media had less or no effect on a developmental outcome than another type of media. This trend was seen regardless of the geographical location of the study. There is a need for future studies to determine exactly how different types of screen use affect development in children, both to determine how screen use can benefit the health of children, and to for more specific clinical guidelines regarding screen time in youth.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100281"},"PeriodicalIF":0.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144829169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global pediatricsPub Date : 2025-07-26DOI: 10.1016/j.gpeds.2025.100277
Agnese Suppiej , Isabella Longo , Massimo Pettoello-Mantovani
{"title":"The pivotal role of mental health in child and adolescent development","authors":"Agnese Suppiej , Isabella Longo , Massimo Pettoello-Mantovani","doi":"10.1016/j.gpeds.2025.100277","DOIUrl":"10.1016/j.gpeds.2025.100277","url":null,"abstract":"<div><div>Mental health in childhood and adolescence is a complex and evolving concept that goes far beyond the absence of mental illness. It involves achieving critical developmental and emotional milestones, building strong social skills that foster positive relationships, and cultivating resilience through effective coping strategies for life’s challenges. Recognizing mental health as a dynamic process, this view underscores its continuous evolution as young people grow and interact with their surroundings.</div><div>This commentary is prepared by the coordinators of the meeting on the importance of promoting child mental health, held on 9 November 2024 in Piazzola sul Brenta, Padua, Italy. The event was promoted and supported by the <em>GE Ghirardi Foundation</em> in collaboration with the Union of National European Pediatric Societies and Associations (EPA-UNEPSA), as part of the global initiatives marking World Mental Health Day 2024.</div><div>The initiative seeks to raise awareness—among healthcare professionals, educators, policymakers, and the wider public—about the essential role of mental health in the overall development of children and adolescents. The commentary provides a concise overview of the key determinants that support a healthy transition to adulthood and highlights the pressing need to protect and nurture the mental well-being of young people during this critical stage of life.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100277"},"PeriodicalIF":0.0,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144722335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global pediatricsPub Date : 2025-07-25DOI: 10.1016/j.gpeds.2025.100276
Antonio D’Avino , Angel Carrasco-Sanz , Anna Libera Latino , Maria Pastore , Ida Giardino , Massimo Pettoello-Mantovani , Francesca Scaltrito , Domenico Adduce , Maria Teresa Grimaldi , Luigi Nigri
{"title":"The persistent shadow of disparity across the Atlantic: child health determinants and policy implications in Europe and North America","authors":"Antonio D’Avino , Angel Carrasco-Sanz , Anna Libera Latino , Maria Pastore , Ida Giardino , Massimo Pettoello-Mantovani , Francesca Scaltrito , Domenico Adduce , Maria Teresa Grimaldi , Luigi Nigri","doi":"10.1016/j.gpeds.2025.100276","DOIUrl":"10.1016/j.gpeds.2025.100276","url":null,"abstract":"<div><div>Child health serves as a critical barometer of a society's well-being, yet profound disparities persist globally, stemming from \"unequal beginnings\" rooted in socioeconomic, environmental, and systemic factors. This brief review examines the complex determinants of child health inequities across Europe and draws comparisons with the United States. In Europe, despite historical health gains, stagnation and widening gaps are observed in child mortality, chronic illnesses, and mental health, exacerbated by poverty, educational disparities, and fragmented healthcare systems. A significant barrier to effective policy is the pervasive lack of consistent and comparable child health data. In the United States, similar socioeconomic disparities are compounded by deep-seated racial inequities in healthcare access and quality, highlighting the pervasive influence of structural factors beyond insurance coverage. Emerging challenges, such as the escalating burden of mental health conditions, lifestyle-related diseases, and the disproportionate impact of climate change through \"systemic cooling poverty,\" present new complexities. Artificial intelligence offers transformative potential for pediatric care but also carries risks of exacerbating existing disparities if not ethically and equitably implemented. Addressing these multifaceted challenges necessitates a concerted, multi-sectoral approach, emphasizing child-centric integrated care, robust data systems, and sustained political commitment to dismantle the systemic roots of inequity.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100276"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Global pediatricsPub Date : 2025-07-23DOI: 10.1016/j.gpeds.2025.100274
Robert J. O’Connor , Lisa Bohman , Susanna Brink , Andrew N. Carr , Roger D. Gibb , Ioannis Hatzopoulos , Dirk Van Gysel , Stephanie Christen-Zaech
{"title":"Baby wipes with a mildly acidic, pH-buffering system provided better skin condition compared to cotton washcloth and water in two randomized clinical trials","authors":"Robert J. O’Connor , Lisa Bohman , Susanna Brink , Andrew N. Carr , Roger D. Gibb , Ioannis Hatzopoulos , Dirk Van Gysel , Stephanie Christen-Zaech","doi":"10.1016/j.gpeds.2025.100274","DOIUrl":"10.1016/j.gpeds.2025.100274","url":null,"abstract":"<div><h3>Objectives</h3><div>Two parallel studies compared the skin health effects of two different baby wipes products to the use of 100 % cotton washcloth and water (WCW). Two wipe products with lotions of 99 % purified water and acidic, pH-buffering systems were tested. The primary objective was to compare the wipes products to the WCW treatment based on severity of erythema, skin barrier integrity (Trans-epidermal Water Loss; TEWL) and pH of skin in the diapered area.</div></div><div><h3>Methods</h3><div>The two studies were prospective, randomized, blinded, parallel-design studies. The first study enrolled 110 babies approximately 3–9 months of age, and the second study enrolled 106 babies up to 36 months of age. The 14-day product use period was preceded by a 7-day washout period. Erythema grading was done at the perianal area, genitals, intertriginous areas, and the buttocks. TEWL and skin pH measurements were done at the genitals and buttocks, with an additional pH measurement taken at the perineum in the second study.</div></div><div><h3>Results</h3><div>Both baby wipe products resulted in significantly lower erythema scores at the perianal region, with Wipe A also being significantly lower at the genital regions compared to WCW. Skin barrier integrity, measured by TEWL, was better for Wipe A at both 7 and 14 days of use with statistical significance achieved at day 14. No TEWL differences were seen for Wipe B versus WCW. Skin pH was significantly lower than WCW at both perianal region and genitals at both 7 and 14 days of use for both wipes, and at Perineum for Wipe B.</div></div><div><h3>Conclusion</h3><div>Based on the results, the baby wipes were shown to be at least as mild as WCW to baby’s skin as measured by lower mean erythema scores and healthy barrier (lower or equal TEWL). The wipes may also provide potential long-term skin health benefits derived from a lower steady-state skin pH.</div></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"13 ","pages":"Article 100274"},"PeriodicalIF":0.0,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144738350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}