Food frontiers最新文献_第7页

Transcriptomic and metabolomic analyses provide evidence on the biocontrol mechanism responsible for the inhibition of Botrytis cinerea and Alternaria alternata by Bacillus velezensis in kiwifruit 转录组和代谢组分析为韦氏芽孢杆菌抑制猕猴桃灰霉病和交替孢霉的生物防治机制提供了证据

IF 7.4

Food frontiers Pub Date : 2024-08-20 DOI: 10.1002/fft2.459

Shixian Zeng, Xiaojiao Li, Jinsong Leng, Michael Wisniewski, Mingrong Chen, Yong Wang, Jia Liu

{"title":"Transcriptomic and metabolomic analyses provide evidence on the biocontrol mechanism responsible for the inhibition of Botrytis cinerea and Alternaria alternata by Bacillus velezensis in kiwifruit","authors":"Shixian Zeng, Xiaojiao Li, Jinsong Leng, Michael Wisniewski, Mingrong Chen, Yong Wang, Jia Liu","doi":"10.1002/fft2.459","DOIUrl":"https://doi.org/10.1002/fft2.459","url":null,"abstract":"Botrytis cinerea and Alternaria alternata are major pre- and postharvest plant pathogens of kiwifruit and responsible for significant economic losses. Although synthetic fungicides are the main source of controlling these pathogens, their use can lead to pathogen resistance, pollution of the environment, and their residues on agricultural produce can represent a health risk to humans. Bacillus velezensis is an ecofriendly bacterium with biocontrol potential. The objectives of the present study were to determine the efficacy of B. velezensis against B. cinerea and A. alternata, both of which are pre- and postharvest pathogens of kiwifruit, and investigate the mechanisms responsible for its biocontrol activity using transcriptomic and metabolomic methodology. Dual cultures of B. velezensis and either B. cinerea or A. alternata versus single cultures were used to conduct a transcriptomic and metabolomic analyses to provide insight into the mechanism by which B. velezensis inhibits B. cinerea and A. alternata. A total of 2499 and 3248 differentially expressed genes (DEGs) were identified in the B. velezensis/B. cinerea and B. velezensis/A. alternata comparisons, respectively. Genes related to sporulation, virulence, and hydrolase activity were downregulated in B. cinerea and A. alternata. Genes associated with MAPK signaling and the TCA cycle were also downregulated. Our study provides new insights into mechanism underlying the inhibition of B. cinerea and A. alternata by B. velezensis. Our results also demonstrate the potential of B. velezensis as a biocontrol agent against these two major pathogens of kiwifruit.","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"5 6","pages":"2623-2640"},"PeriodicalIF":7.4,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.459","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142642388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Updated evidence on raspberries as functional foods: Anticancer bioactivity and therapeutic implications 树莓作为功能性食品的最新证据：抗癌生物活性和治疗意义

IF 7.4

Food frontiers Pub Date : 2024-08-20 DOI: 10.1002/fft2.461

Elena Azzini, Lorenzo Barnaba, Maria Mattera, Daniela Calina, Javad Sharifi-Rad, William C. Cho

引用次数: 0

The significance of cultural context in the classification of preferred mouth behavior: Exploring eating behavior using causal network analysis 文化背景在口腔行为偏好分类中的意义：利用因果网络分析探索饮食行为

IF 7.4

Food frontiers Pub Date : 2024-08-11 DOI: 10.1002/fft2.457

Syahmeer How, Kevin Kantono, Pia I. Hedelund, Nazimah Hamid, Adlin Najihah Azhar, Aishwarya Ventrakamani, Alifdalino Sulaiman

{"title":"The significance of cultural context in the classification of preferred mouth behavior: Exploring eating behavior using causal network analysis","authors":"Syahmeer How, Kevin Kantono, Pia I. Hedelund, Nazimah Hamid, Adlin Najihah Azhar, Aishwarya Ventrakamani, Alifdalino Sulaiman","doi":"10.1002/fft2.457","DOIUrl":"https://doi.org/10.1002/fft2.457","url":null,"abstract":"Preferred mouth behavior studies have mostly focused on Western populations using the JBMB tool to determine how food is manipulated in the mouth. The objective of this study was to determine the relationship between preferred mouth behavior and eating behavior among the diverse group of 209 Malaysians participants. A series of Analysis of Variances and an unsupervised machine learning technique known as Latent Class Clustering were utilized to determine individual's oral behavior. The Adult Eating Behavior Questionnaire was later modeled using causal networks, specifically Partial Least Squares-Confirmatory Factor Analysis, to uncover relationship between appetitive qualities. The results from this study showed that cultural context and appropriateness play an essential role when classifying preferred mouth behavior using behavioral questionnaires and models. Furthermore, this study also determined the relationship between eating behavior and preferred mouth behavior, as well as unique differences in eating behavior observed among the mouth behavior groups.","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"5 5","pages":"2084-2093"},"PeriodicalIF":7.4,"publicationDate":"2024-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.457","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142169859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of promising lactic acid bacteria for the fermentation of lupine- and faba bean-based substrates to produce refreshing protein-rich beverages—A strain screening 鉴定有望用于羽扇豆和蚕豆基质发酵的乳酸菌，以生产富含蛋白质的清爽饮料--菌株筛选

IF 7.4

Food frontiers Pub Date : 2024-08-05 DOI: 10.1002/fft2.452

Stefan Ritter, Carolin Luber, Martina Gastl, Thomas Becker

{"title":"Identification of promising lactic acid bacteria for the fermentation of lupine- and faba bean-based substrates to produce refreshing protein-rich beverages—A strain screening","authors":"Stefan Ritter, Carolin Luber, Martina Gastl, Thomas Becker","doi":"10.1002/fft2.452","DOIUrl":"https://doi.org/10.1002/fft2.452","url":null,"abstract":"Lupines and faba beans are rising stars among legumes as sources of valuable, vegan plant-based proteins. To enter new application areas like the production of protein-rich refreshing beverages, the typical beany aroma impression has to be overcome, and the sensory appearance has to be improved, as it can be accomplished with lactic acid fermentation. An extensive strain screening of 70 lactic acid bacteria from 16 genera was performed to identify suitable strains to transform substrates made from lupines and faba beans into refreshing beverages and to improve their sensory characteristics. By analyzing carbohydrate utilization, production of organic acids and aroma compounds, and sensory appearance, 22 strains for lupine and eight strains for faba bean were preselected. Subsequently, the most suitable strains (five for lupine and three for faba beans) were identified by a trained sensory panel, and finally their growth kinetics were discussed. Generally, the aroma profile varied highly with the utilized strain. However, by selecting suitable strains, the beany impression can be highly reduced and pleasant aroma impressions (e.g., fruity and buttermilk) can be added. Most strikingly, it was proven that using germinated lupines and faba beans instead of raw ones can bypass the usual growth restriction, and the strain selection can be focused exclusively on sensory aspects. This opens the option to use strains usually excluded for the fermentation of legumes due to their lack of utilization of the legume-typical α-galactosides.","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"5 5","pages":"2094-2121"},"PeriodicalIF":7.4,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.452","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142169920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Natural active products in fruit postharvest preservation: A review 水果采后保鲜中的天然活性产品：综述

IF 7.4

Food frontiers Pub Date : 2024-07-30 DOI: 10.1002/fft2.454

Yufeng Sun, Ran Tao, Yang Ju, Jiajing Duan, Qinfei Xie, Bei Fan, Fengzhong Wang

{"title":"Natural active products in fruit postharvest preservation: A review","authors":"Yufeng Sun, Ran Tao, Yang Ju, Jiajing Duan, Qinfei Xie, Bei Fan, Fengzhong Wang","doi":"10.1002/fft2.454","DOIUrl":"https://doi.org/10.1002/fft2.454","url":null,"abstract":"Abundantly available plants, animals, and microbes are excellent source of active substance to be used as fruit preservatives to delay postharvest fruit from decay, maintain good quality, and increase the shelf life. Although they are effective and free from toxicological risks, the use of the natural active products in agriculture is still limited due to the high cost of producing, complexity interaction in food matrix, and unacceptance of odor. This review focuses on employing naturally occurring bioactive compounds as an alternative to the synthetic preservatives used in fruit. For this purpose, natural compounds from abundantly available source, such as plants, animals, and microbes, are systematically described for their properties, mechanism of action, and applicability. Different postharvest handling of bioactive compounds and mechanism of their triggered/controlled release properties are discussed, especially with regard to challenge and future directions of these new strategy to preserve fruit in industry. This review offers a fundamental theory and technologies to develop the efficient and safe alternative strategies to synthetic fruits preservatives. Overall, the utilization of natural preservative techniques offers promising opportunities to maintain quality and extend shelf life of fruit, with potential applications in various industries such as vegetables, meat, and processed food.","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"5 5","pages":"2043-2083"},"PeriodicalIF":7.4,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.454","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142170328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review of sphingolipids from marine sources and their analytical method, metabolic process, and essential roles in human health 综述海洋来源的鞘磷脂及其分析方法、代谢过程和在人类健康中的重要作用

IF 7.4

Food frontiers Pub Date : 2024-07-28 DOI: 10.1002/fft2.450

Xinwen Wang, Mantong Zhao, Guanghua Xia, Haohao Shi, Chuan Li, Xuanri Shen, Kanyasiri Rakariyatham, Saijun He, Zhongyuan Liu, Dayong Zhou

引用次数: 0

In vitro, in vivo, and in silico evidence for the use of plant pigments betalains as potential nutraceuticals against Alzheimer's disease 将植物色素甜菜苷用作预防阿尔茨海默病的潜在营养保健品的体外、体内和硅学证据

IF 7.4

Food frontiers Pub Date : 2024-07-24 DOI: 10.1002/fft2.453

Pedro Martínez-Rodríguez, Paula Henarejos-Escudero, Samanta Hernández-García, Álvaro Sánchez-Ferrer, Fernando Gandía-Herrero

{"title":"In vitro, in vivo, and in silico evidence for the use of plant pigments betalains as potential nutraceuticals against Alzheimer's disease","authors":"Pedro Martínez-Rodríguez, Paula Henarejos-Escudero, Samanta Hernández-García, Álvaro Sánchez-Ferrer, Fernando Gandía-Herrero","doi":"10.1002/fft2.453","DOIUrl":"10.1002/fft2.453","url":null,"abstract":"Anti-amyloidogenic properties of plant pigments betalains as potential nutraceuticals against Alzheimer's disease have been screened using 24 pure molecules. Twenty-two betalains reduced amyloid aggregation in vitro, eight of them up to 100%, with IC50 values in the micromolar range. Atomic force and transmission electron microscopy images showed the typical fibrils associated with Alzheimer's disease and how betalains avoid its formation. Neuroprotection after ingestion was supported by in vivo experiments with Caenorhabditis elegans. Indoline-betacyanin was the most effective molecule by significantly improving the chemotactic behavior of the CL2355 strain, a model of Alzheimer's disease. Furthermore, in-depth molecular docking analyses revealed that the pigments interact with the N-terminal region of the amyloid peptide. This work is the most comprehensive study in the field and provides in vitro, in vivo, and in silico evidence for the use of betalains as nutraceuticals of relevance in the prevention of Alzheimer's disease.","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"5 5","pages":"2137-2154"},"PeriodicalIF":7.4,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.453","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141807806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel organoids mode evaluating the food nutrition and safety: Current state and future prospects 评估食品营养与安全的新型有机体模式：现状与前景

IF 7.4

Food frontiers Pub Date : 2024-07-22 DOI: 10.1002/fft2.451

Fengling Tan, Pengfei Cui, Siting Li, Yingxia Tan, Aijin Ma

{"title":"Novel organoids mode evaluating the food nutrition and safety: Current state and future prospects","authors":"Fengling Tan, Pengfei Cui, Siting Li, Yingxia Tan, Aijin Ma","doi":"10.1002/fft2.451","DOIUrl":"10.1002/fft2.451","url":null,"abstract":"Food nutrition and safety are the cornerstones of food industry, and appropriate research models are crucial. Unlike traditional animal models, the novel organoid model with unique humanization and genome stability has attracted great attentions in food research. However, there lacks systematic review on the application of organoids in food research. This review compared the organoid model with traditional animal and two-dimensional cell models, followed by a systemic evaluation of the organoid model in food nutrition and safety regarding foodborne pathogenic bacteria, functional food factors, toxicology, flavor perception, and so on. Furthermore, emerging micromachining technologies such as microfluidic technology and three-dimensional (3D) bioprinting were analyzed to improve the microenvironment and maturity of organoids. Although organoids overcome some shortcomings associated with traditional models, there are still some challenges to simulate the in vivo microenvironment fully. The development direction of organoids is integrating advanced technologies such as microfluidic technology, novel biomaterial scaffold, and 3D bioprinting with multi-organ coculture technology and multi-scale real-time monitoring systems. The innovative development of organoid technology is expected to provide a theoretical basis for developing future foods represented by cell-cultured meat and synthetic biological foods and for the research of food nutrition and safety.","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"5 5","pages":"1999-2014"},"PeriodicalIF":7.4,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.451","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141817232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural difference analysis of gut microbiota in different bone mass populations and relevant probiotic (lactobacilli) supplementation strategies 不同骨量人群肠道微生物群结构差异分析及相关益生菌（乳酸菌）补充策略

IF 7.4

Food frontiers Pub Date : 2024-07-22 DOI: 10.1002/fft2.449

Jiani Pan, Pingping Yin, Leilei Yu, Heng Zhang, Chengcheng Zhang, Jianxin Zhao, Fengwei Tian, Qixiao Zhai

{"title":"Structural difference analysis of gut microbiota in different bone mass populations and relevant probiotic (lactobacilli) supplementation strategies","authors":"Jiani Pan, Pingping Yin, Leilei Yu, Heng Zhang, Chengcheng Zhang, Jianxin Zhao, Fengwei Tian, Qixiao Zhai","doi":"10.1002/fft2.449","DOIUrl":"10.1002/fft2.449","url":null,"abstract":"Disruption of the bone metabolic balance with advancing age leads to an escalating prevalence of bone-related diseases, significantly compromising individuals’ quality of life. The gut microbiota actively participates in the regulation of bone metabolism, and perturbations in the gut microbiota can exacerbate bone diseases by compromising gut barrier integrity. Determining the microbial taxa involved in bone loss could offer valuable insights into the development of alternative therapies and nutritional interventions for disease management. Therefore, based on metagenomic and 16S ribosomal RNA data, this study analyzed the gut microbiota structure of 488 individuals with different bone masses (NC, normal; ON, osteopenia; OP, osteoporosis) to identify significant associations between the gut microbiota and bone loss. The results showed that at the genus and species levels, the microbiota diversity of the ON population increased, whereas that of the OP population decreased. Bacteroides were significantly enriched in the OP population, whereas the beneficial bacteria Bifidobacterium, Akkermansia, and lactobacilli decreased. Subsequent analyses revealed no significant variation in different bone populations in terms of Bifidobacterium levels, whereas lactobacilli exhibited diverse responses across distinct bone populations. The administration of lactobacilli effectively enhanced lumbar spine bone mineral density and modulated the gut microbiota structure in a population with unhealthy bone mass. This study contributes to the validation of the association between the gut microbiota and bone mass, enhances our understanding of the potential impact of probiotics (lactobacilli) on bone mass, and establishes a robust scientific basis for the application of probiotics in the regulation of bone mass.","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"5 5","pages":"2122-2136"},"PeriodicalIF":7.4,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.449","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141815599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Whey protein hydrolysate intervention ameliorates memory deficits in APP/PS1 mice: Unveiling gut microbe–short-chain fatty acid–brain axis 乳清蛋白水解物干预可改善APP/PS1小鼠的记忆缺陷：揭示肠道微生物-短链脂肪酸-脑轴

IF 7.4

Food frontiers Pub Date : 2024-07-14 DOI: 10.1002/fft2.448

Yongjie Zhou, Hanxiu Meng, Ning Ding, Hui Hong, Yongkang Luo, Chao Wu, Yuqing Tan

{"title":"Whey protein hydrolysate intervention ameliorates memory deficits in APP/PS1 mice: Unveiling gut microbe–short-chain fatty acid–brain axis","authors":"Yongjie Zhou, Hanxiu Meng, Ning Ding, Hui Hong, Yongkang Luo, Chao Wu, Yuqing Tan","doi":"10.1002/fft2.448","DOIUrl":"10.1002/fft2.448","url":null,"abstract":"The intricate causes of Alzheimer's disease (AD) hinder effective, lasting treatment. Although the dietary modulation of the brain–gut axis was explored for AD therapy, the exact mechanism remains unclear. This study suggested that 140 days of the whey protein hydrolysate (WPH) intake could attenuate the AD pathologic symptoms in APP/PS1 transgenic mice via a bidirectional action of the gut microbe–SCFA (short-chain fatty acid)–brain axis. Behavioral tests demonstrated that high-dose WPH (WPH-H, 100 mg/kg body weight [bw]) improved passive and recognition memory in mice. Furthermore, WPH-H significantly reduced amyloid beta 1–42 (Aβ1–42) levels in serum (p < .05) and brain (p < .001) while enhancing serum superoxide dismutase (SOD) activity (p < .01). Brain acetylcholinesterase (p < .01) activity and pro-inflammatory factors in serum were also reduced. Notably, WPH-H remodeled gut microbiota composition by increasing Dubosiella and decreasing Bacteroides and norank_f__Ruminococcaceae while stimulating SCFA production. Proteomics indicated that WPH enhanced neurotoxic Aβ autophagy, synaptogenesis, neurotransmitter delivery, and antioxidative stress response via regulated protein expression. Correlation analysis revealed strong links between modified gut microbiota, elevated SCFA levels, and hippocampal protein up-regulation (Atg4b, Nsfl1c, Tcf20, Nr2f1, and Trappc9) and down-regulation (Krt1). Overall, the amelioration of memory deficits in APP/PS1 mice through WPH-H consumption can be attributed to the interconnected interactions among gut microbes, SCFAs, and brain. Our study illuminated the intricate interplay between nutrition, gut health, and memory function, emphasizing WPH's potential in alleviating AD symptoms.","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"5 5","pages":"2171-2187"},"PeriodicalIF":7.4,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.448","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141650588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0