Litong Wang, Yi Li, Kunlun Huang, Qin Wang, Xiaoyun He
{"title":"免疫活性肽的功能及其在肠道炎症中的作用","authors":"Litong Wang, Yi Li, Kunlun Huang, Qin Wang, Xiaoyun He","doi":"10.1002/fft2.441","DOIUrl":null,"url":null,"abstract":"<p>Immunologically active peptides are a class of peptides with immune functions such as enhancing body immunity, regulating cell growth and differentiation, migration, chemotaxis, neurotransmission, and inducing apoptosis of tumor cells. They have many features, such as small molecular weight, strong stability, high biological activity, easy to adjust the structure accurately, and easy to synthesize. Exploring the mechanism of action of immunologically active peptides can help the modification and development of immunologically active peptides. In this article, the functional properties of immunologically active peptides are described from the perspectives of structural classification of immunologically active peptides and regulatory mechanisms. The relationship between structure and function and the application of different mechanisms in diseases are reviewed, focusing on the role in intestinal inflammation.</p>","PeriodicalId":73042,"journal":{"name":"Food frontiers","volume":"6 1","pages":"124-141"},"PeriodicalIF":7.4000,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.441","citationCount":"0","resultStr":"{\"title\":\"Functions of immunologically active peptides and their roles in intestinal inflammation\",\"authors\":\"Litong Wang, Yi Li, Kunlun Huang, Qin Wang, Xiaoyun He\",\"doi\":\"10.1002/fft2.441\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Immunologically active peptides are a class of peptides with immune functions such as enhancing body immunity, regulating cell growth and differentiation, migration, chemotaxis, neurotransmission, and inducing apoptosis of tumor cells. They have many features, such as small molecular weight, strong stability, high biological activity, easy to adjust the structure accurately, and easy to synthesize. Exploring the mechanism of action of immunologically active peptides can help the modification and development of immunologically active peptides. In this article, the functional properties of immunologically active peptides are described from the perspectives of structural classification of immunologically active peptides and regulatory mechanisms. The relationship between structure and function and the application of different mechanisms in diseases are reviewed, focusing on the role in intestinal inflammation.</p>\",\"PeriodicalId\":73042,\"journal\":{\"name\":\"Food frontiers\",\"volume\":\"6 1\",\"pages\":\"124-141\"},\"PeriodicalIF\":7.4000,\"publicationDate\":\"2024-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fft2.441\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Food frontiers\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/fft2.441\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food frontiers","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/fft2.441","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
Functions of immunologically active peptides and their roles in intestinal inflammation
Immunologically active peptides are a class of peptides with immune functions such as enhancing body immunity, regulating cell growth and differentiation, migration, chemotaxis, neurotransmission, and inducing apoptosis of tumor cells. They have many features, such as small molecular weight, strong stability, high biological activity, easy to adjust the structure accurately, and easy to synthesize. Exploring the mechanism of action of immunologically active peptides can help the modification and development of immunologically active peptides. In this article, the functional properties of immunologically active peptides are described from the perspectives of structural classification of immunologically active peptides and regulatory mechanisms. The relationship between structure and function and the application of different mechanisms in diseases are reviewed, focusing on the role in intestinal inflammation.