Dongzhi Chen, Xin Guo, Xuening Sun, Xiang Feng, Kailong Chen, Jinfeng Zhang, Zece Zhu, Xiaofang Zhang, Xin Liu, Min Liu, Li Li, Weilin Xu
{"title":"Back Cover: High-yield upcycling of feather wastes into solid-state ultra-long phosphorescence carbon dots for advanced anticounterfeiting and information encryption (EXP2 6/2024)","authors":"Dongzhi Chen, Xin Guo, Xuening Sun, Xiang Feng, Kailong Chen, Jinfeng Zhang, Zece Zhu, Xiaofang Zhang, Xin Liu, Min Liu, Li Li, Weilin Xu","doi":"10.1002/EXP.20240602","DOIUrl":"https://doi.org/10.1002/EXP.20240602","url":null,"abstract":"<p>This work presents a high-yield approach to recycle duck feather into carbon dots (CDs) via hydrothermal treatment. The resultant CDs exhibit matrix-free solid-state fluorescence under ultraviolet lamp, and long-lived green room-temperature phosphorescence after removing ultraviolet lamp. Furthermore, their ink demonstrates excellent potential in anticounterfeiting and information encryption, offering a distinctive perspective to reclamation of the feather wastes for environmental sustainability.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240602","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fan Bai, Yueyang Deng, Long Li, Ming Lv, Jamoliddin Razzokov, Qingnan Xu, Zhen Xu, Zhaowei Chen, Guojun Chen, Zhitong Chen
{"title":"Frontispiece: Advancements and challenges in brain cancer therapeutics (EXP2 6/2024)","authors":"Fan Bai, Yueyang Deng, Long Li, Ming Lv, Jamoliddin Razzokov, Qingnan Xu, Zhen Xu, Zhaowei Chen, Guojun Chen, Zhitong Chen","doi":"10.1002/EXP.20240603","DOIUrl":"https://doi.org/10.1002/EXP.20240603","url":null,"abstract":"<p>This review offers a comprehensive look at brain tumor treatments, including both physical (radiotherapy, ablation, photodynamic therapy, cold plasma) and non-physical approaches (surgery, chemotherapy, immunotherapy). It discusses mechanisms, side effects, and recent advances, stressing the importance of personalized, multi-modal strategies. Balancing efficacy with patient safety is critical, considering the brain's delicate nature and functional preservation needs\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240603","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Baiyan Sui, Tingting Ding, Xingyi Wan, Yuxiao Chen, Xiaodi Zhang, Yuanbo Cui, Jie Pan, Linlin Li, Xin Liu
{"title":"Front Cover: Piezoelectric stimulation enhances bone regeneration in alveolar bone defects through metabolic reprogramming of macrophages (EXP2 6/2024)","authors":"Baiyan Sui, Tingting Ding, Xingyi Wan, Yuxiao Chen, Xiaodi Zhang, Yuanbo Cui, Jie Pan, Linlin Li, Xin Liu","doi":"10.1002/EXP.20240601","DOIUrl":"https://doi.org/10.1002/EXP.20240601","url":null,"abstract":"<p>Liu et al. developed a wireless piezoelectric hydrogel with BaTiO<sub>3</sub> nanoparticles, generating piezoelectric potentials to reprogram macrophages towards the M2 phenotype, enhancing osteogenesis in bone marrow stem cells and promoting bone regeneration at load-bearing alveolar sites. This piezoelectric-driven osteoimmunomodulation offers new insights for designing next-generation bioactive materials with combined osteoinductive, immunomodulatory, and piezoelectric properties.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240601","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pioneering Exploration for a lasting and sustainable future","authors":"Gaopeng Li, Zhi-Gang Chen, Chengliang Wang","doi":"10.1002/EXP.20240397","DOIUrl":"https://doi.org/10.1002/EXP.20240397","url":null,"abstract":"<p>To address the growing global imperative for a sustainable future, the United Nations (UN) adopted the 2030 Agenda for Sustainable Development with 17 sustainable development goals (SDGs) at the 2015 UN Sustainable Development Summit. The agenda encompasses 17 SDGs, which span critical areas such as life, water, energy, climate, hunger, poverty, justice, peace, good health, high-quality education, decent work and economic growth, science and technology. In 2021, <i>Exploration</i>, an international, cross-disciplinary journal, was launched to contribute to these efforts, aiming to inspire and support actionable steps toward a more sustainable future.</p><p>In a broad sense, all publications in <i>Exploration</i> can be viewed as contributions by researchers and scientists toward a more sustainable world. These contributions encompass: (1) water/salt separation for clean water<sup>[</sup><span><sup>1</sup></span><sup>]</sup>; (2) treatment of obsolete water and degradation of plastics for good sanitation; (3) wearable/implantable electronic devices for biomedical applications and good health<sup>[</sup><span><sup>2</sup></span><sup>]</sup>; (4) biotechnology and pharmacology for good health,<sup>[</sup><span><sup>3</sup></span><sup>]</sup> for example, advanced biomedical materials for disease diagnosis or therapy and progresses in drug delivery and tumor therapy; (5) energy conversion technologies as actions to achieve affordable and clean energy and reduce the carbon emission,<sup>[</sup><span><sup>4</sup></span><sup>]</sup> such as CO<sub>2</sub> reduction technologies to convert CO<sub>2</sub> into organic fuels through electrocatalysis or photocatalysis, hydrogen production from water through electrocatalysis and utilization of solar energy by solar cells or photocatalysis based on perovskites, inverted perovskites, and organics; (6) advanced energy storage technologies with high energy density and long cycle lifespan<sup>[</sup><span><sup>5</sup></span><sup>]</sup> to better harness clean and renewable energies, mitigate the climate change, and make the energy storage devices more convenient and portable.</p><p>We firmly believe that sustainable development is essential for the future of humanity. All scientific and technological advancements that contribute to sustainability fall within the scope of this journal and are, therefore, highly encouraged. Beyond the abovementioned cutting-edge research, we welcome studies in agriculture, electronics, photonics, energies, manufacturing, material science, physical science, environmental science, life science, information science, space science, artificial intelligence, and other fields dedicated to enhancing the quality of life and minimizing humanity's environmental impact. Additionally, topics such as the policies, regulations, and initiatives addressing hunger, poverty, conflicts, and inequalities, aligned with the 17 SDGs, are within our field. Our vision for <i>Exploration</i> is to serve ","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240397","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142868282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inside Front Cover: Conducting polymer hydrogels based on supramolecular strategies for wearable sensors (EXP2 5/2024)","authors":"Zhiyuan Sun, Qingdong Ou, Chao Dong, Jinsheng Zhou, Huiyuan Hu, Chong Li, Zhandong Huang","doi":"10.1002/EXP.20240502","DOIUrl":"https://doi.org/10.1002/EXP.20240502","url":null,"abstract":"<p>This cover showcases typical supramolecular strategies for developing high-performance conductive polymer hydrogels, providing a comprehensive review of their applications in the field of wearable sensors.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240502","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142524731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Front Cover: Neural interfaces: Bridging the brain to the world beyond healthcare (EXP2 5/2024)","authors":"Shumao Xu, Yang Liu, Hyunjin Lee, Weidong Li","doi":"10.1002/EXP.20240501","DOIUrl":"https://doi.org/10.1002/EXP.20240501","url":null,"abstract":"<p>This perspective explores diverse neural interfaces in the brain, offering transformative possibilities for engaging with our environment and enhancing communication. Emphasis is placed on the role of both non-invasive and invasive neural interfaces in transforming practical applications beyond the realm of healthcare, emphasizing the profound implications for remote control, mind connectivity, and integrated urban design.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240501","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142524730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yiming Zhang, Zhi Chen, Songrui Wei, Yujun Zhang, Hai Fu, Han Zhang, Defa Li, Zhongjian Xie
{"title":"Back Cover: Detection of biological loads in sewage using the automated robot-driven photoelectrochemical biosensing platform (EXP2 5/2024)","authors":"Yiming Zhang, Zhi Chen, Songrui Wei, Yujun Zhang, Hai Fu, Han Zhang, Defa Li, Zhongjian Xie","doi":"10.1002/EXP.20240504","DOIUrl":"https://doi.org/10.1002/EXP.20240504","url":null,"abstract":"<p>The brief description of the cover: Sun Wukong can see throught the monster with his golden eyes. The automated robot-driven photoelectrochemical biosensing platform that harnesses the power of the CRISPR/Cas12a system, much like the golden eyes of Sun Wukong, enables fast, ultra-sensitive, and highly specific monitoring of biological loads in sewage, leaving no hiding place for pathogens. This platform provides crucial data support for early warning, prevention, and control of infectious diseases.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240504","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142524733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhaoyang Ye, Linsheng Li, Ling Yang, Li Zhuang, Ashok Aspatwar, Liang Wang, Wenping Gong
{"title":"Inside Back Cover: Impact of diabetes mellitus on tuberculosis prevention, diagnosis, and treatment from an immunologic perspective (EXP2 5/2024)","authors":"Zhaoyang Ye, Linsheng Li, Ling Yang, Li Zhuang, Ashok Aspatwar, Liang Wang, Wenping Gong","doi":"10.1002/EXP.20240503","DOIUrl":"https://doi.org/10.1002/EXP.20240503","url":null,"abstract":"<p>On the cover: The cover image simulates an ancient Chinese battlefield. It cleverly depicts the struggle between the body's immune cells, Mycobacterium tuberculosis and diabetes. The immune cells and Mycobacterium tuberculosis fight each other, killing and injuring both sides. However, diabetes also launches a sustained attack on the immune cells, resulting in a heavy toll on them. The cover picture was created by Wenping Gong and Zhaoyang Ye.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240503","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142524732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guanyi Wang, Xiongmin Mao, Wang Wang, Xiaolong Wang, Sheng Li, Zijian Wang
{"title":"Front Cover: Bioprinted research models of urological malignancy (EXP2 4/2024)","authors":"Guanyi Wang, Xiongmin Mao, Wang Wang, Xiaolong Wang, Sheng Li, Zijian Wang","doi":"10.1002/EXP.20240401","DOIUrl":"https://doi.org/10.1002/EXP.20240401","url":null,"abstract":"<p>Bioprinted research models (BRMs) play a vital role in modern biomedicine. Herein, Wang et al. review the recent advances on the BRMs of urological malignancy, and prospect current challenges and future development directions. BRMs with programmed spatial structures and functions can serve as powerful research tools, and are likely to disrupt traditional research paradigm.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240401","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142021733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Back Cover: Unveiling the importance of the interface in nanocomposite cathodes for proton-conducting solid oxide fuel cells (EXP2 4/2024)","authors":"Yanru Yin, Yifan Wang, Nan Yang, Lei Bi","doi":"10.1002/EXP.20240404","DOIUrl":"https://doi.org/10.1002/EXP.20240404","url":null,"abstract":"<p>This research paper presents a comprehensive investigation, spanning from the atomic level to the nanoscale and culminating in the development of prototype fuel cells. By exploring the functionality of the cathode interface in proton-conducting solid oxide fuel cells (H-SOFCs), it has been discovered that the interfaces significantly enhance cathode performance, shedding light on the cathode design for H-SOFCs.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240404","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142021781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}