Tamer R Hage, Edward J Kelly, Eriks Ziedins, Babita Parajuli, Cameron S D'Orio, David M Burmeister, Lauren Moffatt, Jeffrey W Shupp, Bonnie C Carney
{"title":"Pilot Study on Resuscitation Volume's Effect on Perfusion and Inflammatory Cytokine Expression in Peri-Burn Skin: Implications for Burn Conversion.","authors":"Tamer R Hage, Edward J Kelly, Eriks Ziedins, Babita Parajuli, Cameron S D'Orio, David M Burmeister, Lauren Moffatt, Jeffrey W Shupp, Bonnie C Carney","doi":"10.3390/ebj6030042","DOIUrl":"10.3390/ebj6030042","url":null,"abstract":"<p><p>Fluid resuscitation after thermal injury is paramount to avoid burn shock and restore organ perfusion. Both over- and under-resuscitation can lead to unintended consequences affecting patient outcomes. While many studies have examined systemic effects, limited data exist on how fluid resuscitation impacts burn wound progression in the acute period. Furthermore, the mechanisms underlying burn wound progression remain not fully understood. This study used a swine model to investigate how varying resuscitation levels affect peri-burn wound dynamics. Twenty-seven female Yorkshire pigs were anesthetized, subjected to 40% total body surface area burn and 15% hemorrhage, then randomized (<i>n</i> = 9) to receive decision-support-driven (adequate, 2-4 mL/kg/%TBSA), fluid-withholding (under, <1 mL/kg/%TBSA), or high-constant-rate (over, >>4 mL/kg/%TBSA) resuscitation. Pigs were monitored for 24 h in an intensive care setting prior to necropsy. Laser Doppler Imaging (LDI) was conducted pre-burn and at 2, 6, 12, and 24 h post burn to assess perfusion. Biopsies were taken from burn, peri-burn (within 2 cm), and normal skin. RNA was isolated at 24 h for the qRT-PCR analysis of IL-6, CXCL8, and IFN-γ. At hour 2, LDI revealed increased peri-burn perfusion in over-resuscitated animals vs. under-resuscitated animals (<i>p</i> = 0.0499). At hour 24, IL-6 (<i>p</i> = 0.0220) and IFN-γ (<i>p</i> = 0.0253) were elevated in over-resuscitated peri-burn skin. CXCL8 showed no significant change. TUNEL staining revealed increased apoptosis in over- and under-resuscitated peri-burn skin. Differences in perfusion and cytokine expression based on resuscitation strategy suggest that fluid levels may influence burn wound progression.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 3","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jan Akkan, Mahsa Bagheri, Sophia Mezger, Paul Christian Fuchs, Maria von Kohout, Wolfram Heitzmann, Rolf Lefering, Jennifer Lynn Schiefer
{"title":"Can Pure Silk Compete with the Established Mepilex Ag<sup>®</sup> in the Treatment of Superficial Partial Thickness Burn Wounds? A Prospective Intraindividual Study.","authors":"Jan Akkan, Mahsa Bagheri, Sophia Mezger, Paul Christian Fuchs, Maria von Kohout, Wolfram Heitzmann, Rolf Lefering, Jennifer Lynn Schiefer","doi":"10.3390/ebj6030041","DOIUrl":"10.3390/ebj6030041","url":null,"abstract":"<p><strong>Introduction: </strong>Superficial partial thickness burns generally do not require surgical intervention and are managed with specialized wound dressings. Mepilex Ag<sup>®</sup> is commonly used and often represents the standard of care. This study evaluated the clinical performance of pure silk compared to Mepilex Ag<sup>®</sup>.</p><p><strong>Methods: </strong>A prospective, single-center intraindividual study was conducted on adult patients with superficial partial thickness burns. Each burn wound was divided, treating one half with pure silk and the other with Mepilex Ag<sup>®</sup>. Clinical parameters including wound closure time, pain levels, and scar quality at 3-month follow-up were analyzed.</p><p><strong>Results: </strong>Twenty-four patients were included (mean TBSA: 5.8%). Mepilex Ag<sup>®</sup> showed a trend towards a shorter wound closure time (10.5 vs. 11.5 days; <i>p</i> = 0.223). Pain scores remained below 4/10 for both dressings throughout treatment. However, Mepilex Ag<sup>®</sup> demonstrated significantly lower pain on day one (3.5 vs. 2.77; <i>p</i> = 0.039) and day two (2.91 vs. 2.27; <i>p</i> = 0.041). Scar quality after 3 months was similar.</p><p><strong>Conclusion: </strong>Both dressings proved to be effective treatment options. Pure silk required fewer resources, showed high clinical practicality, and demonstrated a similar performance to Mepilex Ag<sup>®</sup> in key clinical parameters, making it an interesting option for other clinics and our standard of care.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 3","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12286067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ascanio Tridente, Joanne Lloyd, Pete Saggers, Nicole Lee, Brendan Sloan, Kathryn Puxty, Kayvan Shokrollahi, Nina C Dempsey
{"title":"An Epidemiological Survey of Fluid Resuscitation Practices for Adult Burns Patients in the United Kingdom.","authors":"Ascanio Tridente, Joanne Lloyd, Pete Saggers, Nicole Lee, Brendan Sloan, Kathryn Puxty, Kayvan Shokrollahi, Nina C Dempsey","doi":"10.3390/ebj6030040","DOIUrl":"10.3390/ebj6030040","url":null,"abstract":"<p><p>Fluid management is a critical component in the treatment of patients suffering with major burns. Clinicians must carefully balance judicious resuscitation with the risks of over- or under-resuscitation. We aimed to identify factors associated with survival in burns patients and determine the importance of resuscitation practices. Patients requiring admission to Burns Services in the United Kingdom between 1 April 2022 and 31 March 2023 were included in the National Burns Audit project on fluid resuscitation practices, to evaluate factors associated with survival and Critical Care Length of Stay (CCLoS). A total of 198 patients were included in the analyses, with median age of 51 years (interquartile range, (IQR) 35-62 years), median Total Burn Surface Area (TBSA%) of 27.5% (IQR 20-40%), and median Baux score 82.5 (IQR 66-105). The following were found to be significant for survival: younger age, smaller TBSA%, lower Baux score and independence from renal replacement therapy. Neither the mechanism of burns nor the fluid resuscitation volumes appeared to influence survival. Although interventions such as tracheostomy or the number of surgical procedures did not appear to affect survival, fluid replacement of more than 6 mL/kg/%TBSA independently predicted longer CCLoS. Volume of fluid resuscitation, within the limits examined in this cohort, did not impact likelihood of survival.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 3","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12285936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danielle Rijpma, Karel Claes, Anouk Pijpe, Henk Hoeksema, Ignace De Decker, Jozef Verbelen, Matthea Stoop, Kimberly De Mey, Febe Hoste, Paul van Zuijlen, Stan Monstrey, Annebeth Meij-de Vries
{"title":"Correction: Rijpma et al. Wound and Short-Term Scar Outcomes of Meek Micrografting Versus Mesh Grafting: An Intra-Patient Randomized Controlled Trial. <i>Eur. Burn J.</i> 2025, <i>6</i>, 26.","authors":"Danielle Rijpma, Karel Claes, Anouk Pijpe, Henk Hoeksema, Ignace De Decker, Jozef Verbelen, Matthea Stoop, Kimberly De Mey, Febe Hoste, Paul van Zuijlen, Stan Monstrey, Annebeth Meij-de Vries","doi":"10.3390/ebj6030039","DOIUrl":"10.3390/ebj6030039","url":null,"abstract":"<p><p>In the original publication [...].</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 3","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12285968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Henry Krasner, Emma Chevalier, Samantha Chang, David Slattery, Syed Saquib
{"title":"Exploring Disparities in Pavement Burns: A Comparative Analysis of Housed and Unhoused Burn Patients.","authors":"Henry Krasner, Emma Chevalier, Samantha Chang, David Slattery, Syed Saquib","doi":"10.3390/ebj6030038","DOIUrl":"10.3390/ebj6030038","url":null,"abstract":"<p><p>In some regions, extreme heat can result in pavement temperatures that are high enough to cause severe burn injuries within seconds of skin contact. This risk is elevated for unhoused individuals who may lack adequate clothing and shelter and have susceptibility to other risk factors, including substance use and in turn loss of consciousness. While prior studies have shown worse outcomes for unhoused individuals due to delays in care and higher susceptibility, there is a lack of data on the impact of pavement burns specifically within this population. This single-institution retrospective cohort study aims to explore burn severity and hospital outcomes in housed vs. unhoused patients with pavement burns. The data were analyzed using independent samples <i>t</i>-tests and logistic regression when appropriate, with <i>p</i> < 0.05 considered statistically significant. A total of 305 individuals met the inclusion/exclusion criteria and comprised the final study cohort, 17.7% of which were unhoused. There was no significant difference in TBSA, survival to discharge, or hospital length of stay between housed and unhoused patients. While unhoused individuals may still be at heightened risk for pavement burns due to exposure to extreme heat and a lack of protective measures, these results may additionally suggest consistent emergency care for patients regardless of housing status. Furthermore, these results highlight the importance of developing targeted outreach and prevention programs and equitable emergency care protocols for vulnerable populations.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 3","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12285949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eirini Nikolaidou, Andriana Lazaridou, Christina Iasonidou, Alexandra Tsaroucha, Sophia Papadopoulou, Eleni Kaldoudi, Apostolos Sovatzidis, Despoina Kakagia
{"title":"It Is Written in the Clot: Coagulation Assessment in Severe Burn Injury.","authors":"Eirini Nikolaidou, Andriana Lazaridou, Christina Iasonidou, Alexandra Tsaroucha, Sophia Papadopoulou, Eleni Kaldoudi, Apostolos Sovatzidis, Despoina Kakagia","doi":"10.3390/ebj6030037","DOIUrl":"10.3390/ebj6030037","url":null,"abstract":"<p><strong>Background: </strong>Coagulopathy in severe burn injury is associated with complications and mortality.</p><p><strong>Methods: </strong>We compared 3 tests (EXTEM, INTEM, FIBTEM) of rotational thromboelastometry (ROTEM), a viscoelastic coagulation assay (VCA), with conventional coagulation assays (CCAs), fibrinogen, d-dimers and coagulation factors during the five post-burn days in survivors and non-survivors with severe burn injury, in order to correlate the results with burn coagulopathy and prognosis.</p><p><strong>Results: </strong>Seventeen survivors and ten non-survivors, with mean total burn surface area of 33.78% were included. CCAs measurements were abnormal, but unable to detect coagulopathy. At day 2, D-dimers and fibrinogen levels were statistically augmented for non-survivors. Regarding VCAs, FIBTEM MCF increased for non-survivors at day 2 and remained increased for the whole post-burn period. Furthermore, FIBTEM A10 and A20 at day 2 and EXTEM A10, EXTEM A20, EXTEM MCF, and EXTEM CFT at day 5 took abnormal values for the same group (<i>p</i> < 0.05). These changes were underlined through abnormal measurements of coagulation factors.</p><p><strong>Conclusions: </strong>CCAs are poor indicators of coagulation status in burn injury, whereas VCAs are more sensitive markers, demonstrating coagulopathy and patients at greater risk of mortality.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 3","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12285928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kelly Aranka Ayli Kwa, Annika Catherina Reuvers, Jorien Borst-van Breugel, Anouk Pijpe, Paul P M van Zuijlen, Roelf S Breederveld, Annebeth Meij-de Vries
{"title":"Hand Function Recovers to Near Normal in Patients with Deep Dermal Hand Burns Treated with Enzymatic Debridement: A Prospective Cohort Study.","authors":"Kelly Aranka Ayli Kwa, Annika Catherina Reuvers, Jorien Borst-van Breugel, Anouk Pijpe, Paul P M van Zuijlen, Roelf S Breederveld, Annebeth Meij-de Vries","doi":"10.3390/ebj6020036","DOIUrl":"10.3390/ebj6020036","url":null,"abstract":"<p><p>Short- and long-term hand function was evaluated in adult patients with deep dermal and full-thickness hand burns after treatment with enzymatic debridement (NexoBrid<sup>®</sup> MediWound Ltd., Yavne, Israel), assessing the results at discharge and 3, 6, and 12 months post-burn. This prospective cohort study was performed in the Burn Center in Beverwijk between March 2017 and December 2019. Hand function was assessed using Modified Kapandji Index scores, the Jebsen-Taylor Hand Function Test, and range of motion; scar quality using the Patient and Observer Scar Assessment Scale version 2.0; and quality of life using the Quick Disability Arm Shoulder Hand Questionnaire and the Canadian Occupational Performance Measure. Ten patients (14 hand burns) were included. The need for a skin graft after NexoBrid<sup>®</sup> was 86%, and 50% needed additional surgical excision before skin grafting. Digits 3 and 4 achieved near-to-normal total active motion, and at least 50% of the hands achieved a normal range within the Jebsen-Taylor Hand Function Test in four items at 12 months post-burn. Scar quality and quality of life improved significantly over time. The present study can be considered as a proof-of-concept study for future clinical trials on enzymatic debridement for hand burns.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marianne Kruse, Ida Katinka Lenz, David Josuttis, Philip Plettig, Klaus Hahnenkamp, Denis Gümbel, Claas Güthoff, Bernd Hartmann, Martin Aman, Marc Dominik Schmittner, Volker Gebhardt
{"title":"Characterisation of Fluid Administration in Burn Shock-A Retrospective Cohort Analysis.","authors":"Marianne Kruse, Ida Katinka Lenz, David Josuttis, Philip Plettig, Klaus Hahnenkamp, Denis Gümbel, Claas Güthoff, Bernd Hartmann, Martin Aman, Marc Dominik Schmittner, Volker Gebhardt","doi":"10.3390/ebj6020035","DOIUrl":"10.3390/ebj6020035","url":null,"abstract":"<p><strong>Background: </strong>Finding the optimal amount of fluid is a major challenge in burn shock. Although there is evidence that a restrictive fluid regime is beneficial, current practice shows fluid resuscitation still well above recommendations. The extent of trauma, pre-hospital care and the patient's pre-existing conditions influence requirements.</p><p><strong>Methods: </strong>We analysed outcomes and influencing factors of fluid regimes in a retrospective cohort study including 90 severely burnt patients resuscitated with the same protocol.</p><p><strong>Results: </strong>The mean amount of fluids in the first 24 h was 6.5 mL/kg bodyweight (BW)/% total burn surface area (TBSA). A total of 14% received restrictive (<4), 34% received liberal (4-6) and 51% received excessive (>6) mL/kgBW/%TBSA fluids. There was no difference regarding mortality, age, complications, organ failure, inhalation injury or full-thickness burns in the groups. Patients with excessive fluid therapy had a significantly lower ABSI score (9 vs. 11, <i>p</i> = 0.05) and TBSA (35 vs. 51%, <i>p</i> < 0.001), while patients with a restrictive fluid therapy needed fewer incidences of surgery to cover burn wounds (3.5 vs. 9.0 vs. 7.0, <i>p</i> = 0.008). History of liver disease or alcohol abuse tended to indicate excessive fluid administration. Patients with pre-existing heart failure received restrictive fluid therapy (23 vs. 3 vs. 4%, <i>p</i> = 0.03).</p><p><strong>Conclusions: </strong>Individualised, timely therapy monitoring is as essential as identifying patients with a higher or lower fluid requirement. Excessive fluid resuscitation had fewer deleterious consequences in complications than expected but seems to influence wound healing. Awareness of circumstances that prompt deviations from recommended fluid rates remains elementary.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eva Verdaguer, Antonio Bulla, Jordi Serracanta, Danilo Rivas, Juan P Barret
{"title":"Anterolateral Thigh Flap for Acute/Primary Burn Reconstruction.","authors":"Eva Verdaguer, Antonio Bulla, Jordi Serracanta, Danilo Rivas, Juan P Barret","doi":"10.3390/ebj6020034","DOIUrl":"10.3390/ebj6020034","url":null,"abstract":"<p><strong>Introduction: </strong>The indication for a free flap in acute burn reconstruction is very specific. It should avoid several complications that are more common in the burned patient population. We propose an anterolateral thigh (ALT) flap as a first option for primary burn reconstruction in microvascular free flap reconstruction in burned patients.</p><p><strong>Patients and methods: </strong>A retrospective review of all acutely burned patients treated with microvascular ALT free flap reconstruction between the years 2005 and 2022 in the Vall d'Hebron Barcelona Hospital Campus Burn Centre was conducted.</p><p><strong>Results: </strong>We performed 30 ALT flaps for primary burn reconstruction. The majority of patients were male (87.5%), with a mean age of 36.7 years, and 37% of patients were smokers. High-voltage electrical burns were the most common etiology. The mean time between burn injury and microsurgery was 22 days. The main recipient site was the lower limb. The flap survival rate was 96.6%. One patient required a meshed skin graft to cover a defect in the proximal third due to peripheral flap necrosis. One flap experienced mild congestion, which resolved spontaneously. Another flap had a local infection, which resolved with antibiotic therapy and surgical debridement.</p><p><strong>Conclusions: </strong>An ALT flap offers several advantages to a burned patient, provided that the surgical technique and postoperative management described in this study are followed. We propose it as the first option for primary burn reconstruction using free flaps in a burned patient.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Jolly Neriamparambil, Richard Wong She, Paul Andrew Baker, Lindsay Damkat-Thomas, Joyce Antony
{"title":"Review of the 100 Most Cited Articles in <i>Burns</i> from 2014 to 2024: A Bibliometric Analysis.","authors":"Anna Jolly Neriamparambil, Richard Wong She, Paul Andrew Baker, Lindsay Damkat-Thomas, Joyce Antony","doi":"10.3390/ebj6020033","DOIUrl":"10.3390/ebj6020033","url":null,"abstract":"<p><p>Substantial research interest has been shown over the past ten years in the management of burn injuries. This bibliometric analysis aims to identify and evaluate the most cited articles that have significantly advanced the field of burn injury management. The 100 most cited articles published from January 2014 to September 2024 were collated using the Web of Science database. The full text of each article was meticulously analyzed for descriptive parameters including subject matter, journal of publication, authorship, institutional affiliation, country of origin, and year of publication. The 100 most cited articles had an average of 203 citations, with the most cited article reaching 754 citations and the least cited article cited 105 times. The subjects ranged from enhancing wound care outcomes to metabolic support, fluid management, and infection prevention and management. These articles were distributed across 59 source journals, with 44% of articles having been published in just ten prominent journals. While bibliometric analyses do not accurately gauge scientific merit, this study illuminates the significant contributions to burn management over the past decade and provides valuable insights into research trends in the field.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}