An Epidemiological Survey of Fluid Resuscitation Practices for Adult Burns Patients in the United Kingdom.

IF 1.2 Q4 CRITICAL CARE MEDICINE
Ascanio Tridente, Joanne Lloyd, Pete Saggers, Nicole Lee, Brendan Sloan, Kathryn Puxty, Kayvan Shokrollahi, Nina C Dempsey
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Abstract

Fluid management is a critical component in the treatment of patients suffering with major burns. Clinicians must carefully balance judicious resuscitation with the risks of over- or under-resuscitation. We aimed to identify factors associated with survival in burns patients and determine the importance of resuscitation practices. Patients requiring admission to Burns Services in the United Kingdom between 1 April 2022 and 31 March 2023 were included in the National Burns Audit project on fluid resuscitation practices, to evaluate factors associated with survival and Critical Care Length of Stay (CCLoS). A total of 198 patients were included in the analyses, with median age of 51 years (interquartile range, (IQR) 35-62 years), median Total Burn Surface Area (TBSA%) of 27.5% (IQR 20-40%), and median Baux score 82.5 (IQR 66-105). The following were found to be significant for survival: younger age, smaller TBSA%, lower Baux score and independence from renal replacement therapy. Neither the mechanism of burns nor the fluid resuscitation volumes appeared to influence survival. Although interventions such as tracheostomy or the number of surgical procedures did not appear to affect survival, fluid replacement of more than 6 mL/kg/%TBSA independently predicted longer CCLoS. Volume of fluid resuscitation, within the limits examined in this cohort, did not impact likelihood of survival.

英国成人烧伤患者液体复苏实践的流行病学调查。
液体管理是治疗严重烧伤患者的关键组成部分。临床医生必须仔细权衡明智的复苏与过度或复苏不足的风险。我们的目的是确定与烧伤患者生存相关的因素,并确定复苏实践的重要性。在2022年4月1日至2023年3月31日期间,需要在英国烧伤服务部门住院的患者被纳入国家烧伤审计项目的液体复苏实践,以评估与生存和重症监护住院时间(CCLoS)相关的因素。分析共纳入198例患者,中位年龄51岁(四分位数范围,(IQR) 35-62岁),中位总烧伤表面积(TBSA%) 27.5% (IQR 20-40%),中位Baux评分82.5 (IQR 66-105)。以下因素对生存率有显著影响:年龄更小,TBSA%更小,Baux评分更低,不依赖肾脏替代治疗。烧伤机制和液体复苏量似乎都不影响生存。虽然气管造口术或手术次数等干预措施似乎不影响生存,但补液量超过6 mL/kg/%TBSA独立预测CCLoS延长。在本队列中检查的范围内,液体复苏的体积不影响生存的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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