European burn journal最新文献

{"title":"Pediatric Burn Treatment with Non-Thermal Atmospheric Plasma and Epifast^®: Clinical Results.","authors":"Pablo Rodríguez-Ferreyra, Régulo López-Callejas, Teresa Narváez-Robles, Benjamín Gonzalo Rodríguez-Méndez, Omar Israel Gayosso-Cerón, Antonio Mercado-Cabrera, Irene Lule-Reyna, Othoniel Mondragón-Dagio, Raúl Valencia-Alvarado, Jesús Duarte-Mote","doi":"10.3390/ebj6020020","DOIUrl":"https://doi.org/10.3390/ebj6020020","url":null,"abstract":"<p><p>The effective treatment of severe burns in pediatric patients is essential for minimizing complications and promoting optimal recovery. This study investigates the use of non-thermal atmospheric pressure plasma (NTAPP) as an adjuvant therapy in combination with Epifast^® for the experimental group, compared to standard care involving early excisions and Epifast^® for the control group. A randomized controlled trial was conducted with 40 pediatric patients suffering from superficial partial-thickness and deep dermal burns. The experimental group that received NTAPP daily demonstrated a significant reduction in the need for skin grafts, requiring only 10% compared to 40% in the control group (<i>p</i> = 0.02). Although there were no statistically significant differences in the length of hospital stay, the experimental group showed a trend toward shorter stays (9.85 days vs. 11.65 days; <i>p</i> = 0.38) and lower analgesic consumption (13.01 doses vs. 21.15 doses; <i>p</i> = 0.09). Additionally, the infection rate in the NTAPP-treated group was significantly lower at 25%, compared to 37.95% in the control group (<i>p</i> < 0.05). These findings suggest that NTAPP enhances wound healing while reducing surgical morbidity and the risk of infections. In conclusion, this study highlights the transformative potential of NTAPP as an innovative strategy in pediatric burn management. It combines clinical efficacy with a less invasive approach, representing a significant advance in regenerative medicine and opening new avenues for research into advanced therapies.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergency Treatment of Burns in Adults-Characteristics of Adult Patients and Acute/Pre-Hospital Burn Management.","authors":"Bogdan Oprita, Georgeta Burlacu, Vlad Mircea Ispas, Ioana Adriana Serban, Ruxandra Oprita","doi":"10.3390/ebj6020019","DOIUrl":"https://doi.org/10.3390/ebj6020019","url":null,"abstract":"<p><strong>Background: </strong>Burns represent one of the most severe injuries encountered in the pre-hospital and ED environment, with essential features and an often negatively powerful impact on patients' quality of life. Preventive measures can significantly reduce the number of cases presenting to medical facilities; knowledge and the correct application of first aid measures in the pre-hospital stage have a significant role in reducing the risk of complications and in obtaining optimal outcomes.</p><p><strong>Methods: </strong>This retrospective one-year single-center study analyzed 399 adult burn patients treated at the Clinical Emergency Hospital of Bucharest (CEHB) in 2023. Information concerning the main characteristics of the patients (age, sex, and residence), etiology and severity of burns, and pre-hospital management of patients was analyzed.</p><p><strong>Results: </strong>Most patients (63.41%) resided in urban areas, with a higher prevalence of males (55.89%). Thermal burns accounted for 77.69% of cases, primarily caused by water, food, oil, or flames. Burns covered ≤10% TBSA in 77.19% of cases, while 6.52% extended beyond 50% TBSA. First aid was provided to 52.63% of patients at the accident site, often by non-specialized individuals. The mean time to presentation was 34.90 h, with significant correlations between time, age, burned body surface area, and burn depth.</p><p><strong>Conclusions: </strong>There is a real need for improvements in first-aid training and health initiatives to enhance pre-hospital burn care. Better documentation of the care provided to patients before being admitted to specialized centers, as well as further studies in this field, are absolutely necessary for improving prevention programs and burn management in the acute stage.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioabsorbable Poly(vinyl alcohol)-Citric Acid Dressings: Wound Healing Studies in an Experimental In Vivo Model.","authors":"Jonalba Mendes Pereira, Emilia Angela Lo Schiavo Arisawa, Antônio Luiz Martins Maia Filho, José Figueredo-Silva, Nicoly Alves, Carolina Hahn da Silveira, Lucia Vieira","doi":"10.3390/ebj6020018","DOIUrl":"https://doi.org/10.3390/ebj6020018","url":null,"abstract":"<p><strong>Background: </strong>The wound healing process presents notable challenges for nursing teams, requiring extensive knowledge of wound care materials. A nanoparticle-free, bioabsorbable pol-yvinyl alcohol (PVA) with citric acid (CA) dressing produced by simple electrospin-ning was evaluated to treat acute wound healing in rats. This PVA-CA combination promotes crosslinking, increases the dressing capacity of absorption and confers heal-ing properties due to the citric acid antioxidant action.</p><p><strong>Methods: </strong>The dressing was tested in a quantitative experiment on 1.9 cm acute dermatological lesions in rats (<i>n</i> = 12), com-paring the PVA-CA-treated group with the untreated control group (CG). Samples were collected at 3, 7 and 14 days after lesion induction to evaluate the inflammatory process and tissue healing.</p><p><strong>Results: </strong>The macroscopic and histological data on the third day showed similar characteristics in both groups; however, after fourteen days, the PVA-CA group exhibited complete healing, accompanied by recomposition of the skin layers, whereas the wounds in the CG did not close completely.</p><p><strong>Conclusions: </strong>The results highlight that electrospun PVA-AC dressings improve healing outcomes and constitute a prom-ising and affordable solution, providing a suitable environment for tissue repair, re-ducing inflammatory cell infiltration, blood vessel formation, and restoration of epi-thelial tissue, reducing the time of the healing process of acute wounds.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic and Hormonal Changes in Pediatric Burn Patients: Mechanisms, Evidence, and Care Strategies.","authors":"Gloria Pelizzo, Valeria Calcaterra, Michela Marinaro, Paola Baldassarre, Carlotta Paola Maria Canonica, Gianvincenzo Zuccotti","doi":"10.3390/ebj6020017","DOIUrl":"https://doi.org/10.3390/ebj6020017","url":null,"abstract":"<p><strong>Background: </strong>Burn injuries constitute a significant global health challenge, especially in pediatric populations, where they are a leading cause of morbidity and mortality. Pediatric burns require particular attention due to their unique pathophysiology, long-term consequences on growth and development, and psychological impacts.</p><p><strong>Methods: </strong>We propose a comprehensive review of recent advancements in understanding the key aspects of hormonal and metabolic changes in burned children, aiming to guide therapeutic interventions, improve outcomes, and reduce the global burden of these injuries.</p><p><strong>Results: </strong>Effective management of the physiological stress response in pediatric burn patients necessitates a multidisciplinary approach integrating medical, nutritional, and rehabilitative strategies. Timely nutritional support and individualized plans preserve muscle mass, promote wound healing, and reduce complications and organ dysfunction risk. Advances in pharmacological interventions, such as beta-blockers, anabolic agents, and hormonal treatment, offer promising pathways to improve recovery and mitigate long-term complications. Early mobilization and physiotherapy are essential for preventing complications of prolonged immobility, including muscle wasting, joint contractures, and functional decline; their effectiveness is closely tied to advancements in minimally invasive procedures, regenerative medicine, and reconstructive techniques, particularly for pediatric patients.</p><p><strong>Conclusions: </strong>While current strategies have significantly improved survival and outcomes for pediatric burn patients, ongoing research is critical to refine these new care strategies.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment from the Enhancing Burn Rehabilitation Special Edition Editors on \"Fractional CO₂ Laser for Pediatric Hypertrophic Scars: Lessons Learned from a Prematurely Terminated Split-Scar Trial\".","authors":"Dale W Edgar, Colleen M Ryan, Marianne K Nieuwenhuis, Ulrike Van Daele, Jill M Cancio","doi":"10.3390/ebj6010016","DOIUrl":"10.3390/ebj6010016","url":null,"abstract":"<p><p>The Editors thank the investigators for displaying tenacity, evidenced by the significant revisions that were necessary to complete this project [...].</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11941557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Nutrition and Nutrition Education in the Burn Unit of a Developing Country: A Qualitative Study.","authors":"Jonathan Bayuo, Joyce Pwavra, Jephtah Davids, Anita Eseenam Agbeko, Paa Ekow Hoyte-Williams, Frank Bediako Agyei, Pius Agbenorku","doi":"10.3390/ebj6010015","DOIUrl":"10.3390/ebj6010015","url":null,"abstract":"<p><p>Burn injuries can trigger a series of metabolic and catabolic responses that exert significant impacts on an individual's nutritional status, necessitating continuous nutritional support and education to aid recovery. However, burn units in developing countries often face resource limitations that can negatively affect these needs. This study aimed to explore the challenges related to post-burn nutrition and nutrition education in our burn unit and identify ways to improve the situation. An interpretive description approach was used, and convenience sampling recruited fifty-three participants, including 18 adult burn survivors and their primary caregivers (each as a single dyad), 10 informal caregivers of paediatric burn survivors, and 25 burn care staff. The data were analysed through thematic analysis, revealing three main themes and seven subthemes. The findings highlight an unstructured approach to nutrition and education, along with financial constraints affecting adherence. To address these issues, strategies such as using educational materials like videos and booklets/leaflets in the local language are suggested to develop relevant interventions. In conclusion, while there are concerns about nutrition and education, there are also opportunities to improve the situation.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940866/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recreational Use of Nitrous Oxide as a Source of Frostbite Injuries to the Skin: A Review of the Literature and a Case Report.","authors":"Sebastian Holm, Reza Tabrisi, Johann Zdolsek","doi":"10.3390/ebj6010014","DOIUrl":"10.3390/ebj6010014","url":null,"abstract":"<p><p>Nitrous oxide has a wide range of medical applications, such as being used as an analgesic in general anesthesia, dental procedures, childbirth and sedation. Lately, it has also been employed as an inhalant recreational drug to induce brief euphoria. Recent studies indicate a worldwide rise in the incidence of skin frostbites associated with nitrous oxide use. A scoping review was conducted to synthesize and summarize the existing literature published in English regarding frostbite injuries associated with the recreational use of nitrous oxide. The literature search was carried out in July 2024 using databases such as Embase, Web of Science and PubMed^®. From an initial pool of 83 publications, 8 studies were ultimately selected for full-text review as they met our inclusion criteria for analysis. Additionally, we provide a representative clinical case involving a 21-year-old male who experienced frostbite following skin exposure to nitrous oxide. Most publications on nitrous oxide induced frostbites are from recent years, primarily between 2022 and 2024, with the first case documented in 1996. These injuries are mostly observed in young adults, with a female dominance, and are typically localized to the inner thighs. According to the existing literature, the predominant treatment approach is conservative management, with excision and split-thickness skin grafting (STSG) in the second place. This study represents the first literature review summarizing frostbite injuries to the skin from nitrous oxide misuse. There is a need for enhanced preventive measures to raise public awareness and reduce the incidence of frostbite injuries associated with the recreational use of nitrous oxide.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11941200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Techniques in Fractional Skin Replacement.","authors":"Courtney Kelly, Rodney K Chan, Anders H Carlsson","doi":"10.3390/ebj6010013","DOIUrl":"10.3390/ebj6010013","url":null,"abstract":"<p><p>The gold standards for coverage of wounds that cannot be primarily closed are full thickness skin grafts (FTSGs) and split thickness skins graft (STSGs). FTSGs harvest sites generally require primary closure, which limits availability, especially when treating larger wounds. STSGs have many shortcomings, including donor site morbidity. Fractional autologous skin replacement can be utilized in conjunction with or in lieu of STSGs to both improve graft outcomes of large wounds and to decrease donor site morbidity. Skin can be mechanically or chemically fractionated. Fractionated skin can be advantageous, as adnexal structures provide additional functionality without donor site morbidity. In this review, we will discuss current and emerging techniques in fractional skin replacement.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11941591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary Study on the Development of a Real-Time Pressure-Monitoring Facial Mask for Burn Rehabilitation.","authors":"Hyunjun Shin, Gyung-Jin Jeon, Seok-Jin Hwang, Hyeonseok Cho, Young-Min Cho, Hyoung-Soon Youn, Jisu Seo, Sehoon Park, Yoon-Soo Cho, Gyu-Seok Kim","doi":"10.3390/ebj6010012","DOIUrl":"10.3390/ebj6010012","url":null,"abstract":"<p><p>The most common aftereffect of severe burns in patients is hypertrophic scarring. Hypertrophic scars typically form following severe burns; it refers to excessive collagen production in the dermal layer during the healing process, resulting in an abnormal raised scar. Currently, practical treatments for suppressing hypertrophic scars include laser therapy, pressure therapy, and the application of silicone sheets for moisture retention. The most extensively used treatment involves compression therapy using specially designed garments for the affected areas. However, this method has limitations when applied to curved surfaces like the face. To address this issue, three-dimensional (3D) scanning and 3D printing techniques have been actively developed for face masks and have shown promising clinical results. Unfortunately, current facial masks under development lack a sensor system to measure pressure, making it difficult to ensure consistent and appropriate pressures during clinical trials. In this study, we have developed a burn pressure mask capable of real-time pressure monitoring. The facial mask developed in this study utilizes an FSR-type sensor to measure the pressure applied to the skin. We have also embedded electrical wires within the mask to enhance its comfort and wearability. For this study, two patients wore the facial mask with real-time pressure measurement capabilities for 4 weeks in 12 h per day on average. We evaluated whether the mask maintained the appropriate pressure range (15-25 mmHg) throughout the clinical trial and whether it effectively inhibited scar formation. Through the analysis of recorded pressure signal data, we confirmed that the patients consistently maintained the appropriate pressure while wearing the mask during the clinical trial. Additionally, we observed significant differences in skin moisture levels, transepidermal water loss, and scar thickness before and after the experiment. These findings suggest that the facial mask, featuring real-time monitoring capabilities, effectively prevents the formation of hypertrophic scars.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11941440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mind the Gap! Core-Peripheral Temperature Gradient and Its Relationship to Mortality in Major Burns.","authors":"Niamh Keohane, Jennifer Driver, Randeep Mullhi, Elizabeth Chipp, Barbara Torlinska, Tomasz Torlinski","doi":"10.3390/ebj6010011","DOIUrl":"10.3390/ebj6010011","url":null,"abstract":"<p><p>The association between hypothermia and poor outcomes in severe burn injury is well established. However, the significance of the core-peripheral temperature gradient has not previously been investigated. Institutional guidance at our burns centre advocates avoiding hypothermia and targeting a body temperature between 37.5 and 39.5 °C. The core-peripheral temperature gap should be ≤2 °C, based on expert opinion. Data from 61 patients admitted to the Intensive Care Unit (ICU) with severe burns between 2016 and 2022 were analysed. A higher core temperature at 48 h, avoidance of hypothermia and a core-peripheral temperature gap > 2 °C were associated with reduced odds of mortality. The mean core body temperature and core-peripheral temperature gap increased over the first 48 h (r = 0.5, <i>p</i> < 0.001). All non-survivors had a core-peripheral gap < 2 °C at 48 h. Survivors had a higher mean 48 h gap (1.6 [95%CI:1.3-1.9]) than non-survivors (0.8 [95%CI:0.2-1.4; <i>p</i> = 0.04]). Our findings support previous studies suggesting that avoiding hypothermia and achieving a higher target temperature are associated with reduced mortality. However, it challenges the previous expert consensus that a lower core-peripheral gap indicates better outcomes. Further research with a larger cohort of patients is required to identify whether a higher core-peripheral temperature gap predicts outcomes in critically ill patients with severe burns.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}