European burn journal最新文献

Hand Function Recovers to Near Normal in Patients with Deep Dermal Hand Burns Treated with Enzymatic Debridement: A Prospective Cohort Study. 酶清创治疗手部深层烧伤患者手部功能恢复至接近正常：一项前瞻性队列研究。

IF 1

European burn journal Pub Date : 2025-06-12 DOI: 10.3390/ebj6020036

Kelly Aranka Ayli Kwa, Annika Catherina Reuvers, Jorien Borst-van Breugel, Anouk Pijpe, Paul P M van Zuijlen, Roelf S Breederveld, Annebeth Meij-de Vries

{"title":"Hand Function Recovers to Near Normal in Patients with Deep Dermal Hand Burns Treated with Enzymatic Debridement: A Prospective Cohort Study.","authors":"Kelly Aranka Ayli Kwa, Annika Catherina Reuvers, Jorien Borst-van Breugel, Anouk Pijpe, Paul P M van Zuijlen, Roelf S Breederveld, Annebeth Meij-de Vries","doi":"10.3390/ebj6020036","DOIUrl":"10.3390/ebj6020036","url":null,"abstract":"Short- and long-term hand function was evaluated in adult patients with deep dermal and full-thickness hand burns after treatment with enzymatic debridement (NexoBrid® MediWound Ltd., Yavne, Israel), assessing the results at discharge and 3, 6, and 12 months post-burn. This prospective cohort study was performed in the Burn Center in Beverwijk between March 2017 and December 2019. Hand function was assessed using Modified Kapandji Index scores, the Jebsen-Taylor Hand Function Test, and range of motion; scar quality using the Patient and Observer Scar Assessment Scale version 2.0; and quality of life using the Quick Disability Arm Shoulder Hand Questionnaire and the Canadian Occupational Performance Measure. Ten patients (14 hand burns) were included. The need for a skin graft after NexoBrid® was 86%, and 50% needed additional surgical excision before skin grafting. Digits 3 and 4 achieved near-to-normal total active motion, and at least 50% of the hands achieved a normal range within the Jebsen-Taylor Hand Function Test in four items at 12 months post-burn. Scar quality and quality of life improved significantly over time. The present study can be considered as a proof-of-concept study for future clinical trials on enzymatic debridement for hand burns.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterisation of Fluid Administration in Burn Shock-A Retrospective Cohort Analysis. 烧伤休克中液体给药的特征——回顾性队列分析。

IF 1

European burn journal Pub Date : 2025-06-10 DOI: 10.3390/ebj6020035

Marianne Kruse, Ida Katinka Lenz, David Josuttis, Philip Plettig, Klaus Hahnenkamp, Denis Gümbel, Claas Güthoff, Bernd Hartmann, Martin Aman, Marc Dominik Schmittner, Volker Gebhardt

{"title":"Characterisation of Fluid Administration in Burn Shock-A Retrospective Cohort Analysis.","authors":"Marianne Kruse, Ida Katinka Lenz, David Josuttis, Philip Plettig, Klaus Hahnenkamp, Denis Gümbel, Claas Güthoff, Bernd Hartmann, Martin Aman, Marc Dominik Schmittner, Volker Gebhardt","doi":"10.3390/ebj6020035","DOIUrl":"10.3390/ebj6020035","url":null,"abstract":"Background: Finding the optimal amount of fluid is a major challenge in burn shock. Although there is evidence that a restrictive fluid regime is beneficial, current practice shows fluid resuscitation still well above recommendations. The extent of trauma, pre-hospital care and the patient's pre-existing conditions influence requirements.Methods: We analysed outcomes and influencing factors of fluid regimes in a retrospective cohort study including 90 severely burnt patients resuscitated with the same protocol.Results: The mean amount of fluids in the first 24 h was 6.5 mL/kg bodyweight (BW)/% total burn surface area (TBSA). A total of 14% received restrictive (<4), 34% received liberal (4-6) and 51% received excessive (>6) mL/kgBW/%TBSA fluids. There was no difference regarding mortality, age, complications, organ failure, inhalation injury or full-thickness burns in the groups. Patients with excessive fluid therapy had a significantly lower ABSI score (9 vs. 11, p = 0.05) and TBSA (35 vs. 51%, p < 0.001), while patients with a restrictive fluid therapy needed fewer incidences of surgery to cover burn wounds (3.5 vs. 9.0 vs. 7.0, p = 0.008). History of liver disease or alcohol abuse tended to indicate excessive fluid administration. Patients with pre-existing heart failure received restrictive fluid therapy (23 vs. 3 vs. 4%, p = 0.03).Conclusions: Individualised, timely therapy monitoring is as essential as identifying patients with a higher or lower fluid requirement. Excessive fluid resuscitation had fewer deleterious consequences in complications than expected but seems to influence wound healing. Awareness of circumstances that prompt deviations from recommended fluid rates remains elementary.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anterolateral Thigh Flap for Acute/Primary Burn Reconstruction. 股前外侧皮瓣用于急性/原发性烧伤重建。

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European burn journal Pub Date : 2025-06-10 DOI: 10.3390/ebj6020034

Eva Verdaguer, Antonio Bulla, Jordi Serracanta, Danilo Rivas, Juan P Barret

{"title":"Anterolateral Thigh Flap for Acute/Primary Burn Reconstruction.","authors":"Eva Verdaguer, Antonio Bulla, Jordi Serracanta, Danilo Rivas, Juan P Barret","doi":"10.3390/ebj6020034","DOIUrl":"10.3390/ebj6020034","url":null,"abstract":"Introduction: The indication for a free flap in acute burn reconstruction is very specific. It should avoid several complications that are more common in the burned patient population. We propose an anterolateral thigh (ALT) flap as a first option for primary burn reconstruction in microvascular free flap reconstruction in burned patients.Patients and methods: A retrospective review of all acutely burned patients treated with microvascular ALT free flap reconstruction between the years 2005 and 2022 in the Vall d'Hebron Barcelona Hospital Campus Burn Centre was conducted.Results: We performed 30 ALT flaps for primary burn reconstruction. The majority of patients were male (87.5%), with a mean age of 36.7 years, and 37% of patients were smokers. High-voltage electrical burns were the most common etiology. The mean time between burn injury and microsurgery was 22 days. The main recipient site was the lower limb. The flap survival rate was 96.6%. One patient required a meshed skin graft to cover a defect in the proximal third due to peripheral flap necrosis. One flap experienced mild congestion, which resolved spontaneously. Another flap had a local infection, which resolved with antibiotic therapy and surgical debridement.Conclusions: An ALT flap offers several advantages to a burned patient, provided that the surgical technique and postoperative management described in this study are followed. We propose it as the first option for primary burn reconstruction using free flaps in a burned patient.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review of the 100 Most Cited Articles in Burns from 2014 to 2024: A Bibliometric Analysis. 2014 - 2024年伯恩斯100篇被引次数最多的文章综述：文献计量学分析。

IF 1

European burn journal Pub Date : 2025-06-10 DOI: 10.3390/ebj6020033

Anna Jolly Neriamparambil, Richard Wong She, Paul Andrew Baker, Lindsay Damkat-Thomas, Joyce Antony

{"title":"Review of the 100 Most Cited Articles in Burns from 2014 to 2024: A Bibliometric Analysis.","authors":"Anna Jolly Neriamparambil, Richard Wong She, Paul Andrew Baker, Lindsay Damkat-Thomas, Joyce Antony","doi":"10.3390/ebj6020033","DOIUrl":"10.3390/ebj6020033","url":null,"abstract":"Substantial research interest has been shown over the past ten years in the management of burn injuries. This bibliometric analysis aims to identify and evaluate the most cited articles that have significantly advanced the field of burn injury management. The 100 most cited articles published from January 2014 to September 2024 were collated using the Web of Science database. The full text of each article was meticulously analyzed for descriptive parameters including subject matter, journal of publication, authorship, institutional affiliation, country of origin, and year of publication. The 100 most cited articles had an average of 203 citations, with the most cited article reaching 754 citations and the least cited article cited 105 times. The subjects ranged from enhancing wound care outcomes to metabolic support, fluid management, and infection prevention and management. These articles were distributed across 59 source journals, with 44% of articles having been published in just ten prominent journals. While bibliometric analyses do not accurately gauge scientific merit, this study illuminates the significant contributions to burn management over the past decade and provides valuable insights into research trends in the field.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Potential Use of Fibrin Sealants in Burn Wound Management: A Comprehensive Review of Experimental and Clinical Studies. 纤维蛋白密封剂在烧伤创面管理中的潜在应用：实验和临床研究的综合综述。

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European burn journal Pub Date : 2025-06-05 DOI: 10.3390/ebj6020032

Christina Nikolaou, Maximos Frountzas, Emmanouil I Kapetanakis, Dimitrios Stefanoudakis, Nikolaos A Papadopulos, Stylianos Kykalos, Dimitrios Schizas, Dimitrios Iliopoulos

{"title":"The Potential Use of Fibrin Sealants in Burn Wound Management: A Comprehensive Review of Experimental and Clinical Studies.","authors":"Christina Nikolaou, Maximos Frountzas, Emmanouil I Kapetanakis, Dimitrios Stefanoudakis, Nikolaos A Papadopulos, Stylianos Kykalos, Dimitrios Schizas, Dimitrios Iliopoulos","doi":"10.3390/ebj6020032","DOIUrl":"10.3390/ebj6020032","url":null,"abstract":"Fibrin sealants have been implemented in the management of burn wounds. They can be used either in combination with skin grafts for full-thickness burns or alone for treating superficial and deep dermal burns. The aim of this review was to provide critical insights regarding the efficacy of fibrin sealants in enhancing wound healing, improving graft adherence, and reducing complications. Therefore, evidence from experimental models and clinical trials was synthesized, underscoring the transformative role of fibrin sealants in modern burn care. This comprehensive review includes recent evidence on the potential benefits of fibrin sealants in the management of superficial and deep dermal or full-thickness burn injuries. Clinical and experimental evidence underscores some benefits in utilizing fibrin sealants in the management of superficial and deep dermal burn injuries, or in combination with skin grafts in full-thickness burns. Furthermore, fibrin sealants diminish postoperative pain and facilitate quick recovery for daily activities; however, controversy regarding their cost still remains. This review concludes that fibrin sealants could serve as a safe and effective therapeutic option for burn wound management. The safety and efficacy of their utilization, along with their wide availability and easiness to use, could make them an alternative treatment choice when a specialized plastic surgery service is not available, or in the emergency setting across different healthcare systems.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laboratory-Generated Autologous Skin Substitutes for Burn Treatment in Europe: Narrative Review, Experts' Opinion, and Legal Considerations. 在欧洲，实验室生成的自体皮肤替代品用于烧伤治疗：叙述回顾，专家意见和法律考虑。

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European burn journal Pub Date : 2025-06-03 DOI: 10.3390/ebj6020030

Celine Auxenfans, Rocio G Valencia, Philippe Abdel-Sayed, Miguel Alaminos, Jean-François Brunet, Fernando Campos, Jesus Chato-Astrain, Gloria Carmona, Anthony de Buys Roessingh, Stephanie Droz-Georget, Melinda Farkas, Ana Fernandez Gonzalez, Enikö Gönczi, Fredrik Huss, Bernd Hartmann, Barbara Heusi, Alexandra Karström, Naiem Moiemen, Giulia Sartoris, Antje Spranger, Marina Trouillas, Claudia Rosas, Jyrki Vuola, Vivienne Woodtli, Clemens Schiestl, Sophie Böttcher

{"title":"Laboratory-Generated Autologous Skin Substitutes for Burn Treatment in Europe: Narrative Review, Experts' Opinion, and Legal Considerations.","authors":"Celine Auxenfans, Rocio G Valencia, Philippe Abdel-Sayed, Miguel Alaminos, Jean-François Brunet, Fernando Campos, Jesus Chato-Astrain, Gloria Carmona, Anthony de Buys Roessingh, Stephanie Droz-Georget, Melinda Farkas, Ana Fernandez Gonzalez, Enikö Gönczi, Fredrik Huss, Bernd Hartmann, Barbara Heusi, Alexandra Karström, Naiem Moiemen, Giulia Sartoris, Antje Spranger, Marina Trouillas, Claudia Rosas, Jyrki Vuola, Vivienne Woodtli, Clemens Schiestl, Sophie Böttcher","doi":"10.3390/ebj6020030","DOIUrl":"10.3390/ebj6020030","url":null,"abstract":"Autologous skin substitutes represent a promising advancement in the treatment of burn injuries, offering personalized solutions for patients with extensive skin loss. This white paper synthesizes the current knowledge on laboratory-generated autologous skin substitutes in Europe, incorporating expert opinions and legal considerations. The white paper examines the scientific principles underlying autologous skin substitute development, including cell sourcing, bioengineering techniques, and clinical applications. The regulatory framework governing the production and use of these advanced therapies in Europe is also examined, highlighting challenges in standardization, safety, and approval pathways. The text features expert insights that offer a real-world perspective on the clinical viability and translational hurdles of autologous skin substitutes. The findings highlight the potential of autologous skin substitutes to improve burn treatment outcomes while emphasizing the need for harmonized regulations to facilitate clinical implementation. Despite technological advancements, significant challenges persist, including production costs, scalability, and long-term efficacy. Another focus of this white paper are the legal changes, which have significantly impacted the production and availability of these technologies. The review concludes that while autologous skin substitutes hold great promise, further research, regulatory refinement, and interdisciplinary collaboration are essential to optimize their integration into clinical practice.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cosmetic Outcomes of the First Bodybuilder Using a Low-Cost Modified Culture Technique for Burn Wound Coverage: A Case Report and Long-Term Follow-Up. 首例健美运动员使用低成本改良培养技术进行烧伤创面覆盖的美容效果：一个病例报告和长期随访。

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European burn journal Pub Date : 2025-06-03 DOI: 10.3390/ebj6020029

Wayne George Kleintjes, Tarryn Kay Prinsloo

{"title":"Cosmetic Outcomes of the First Bodybuilder Using a Low-Cost Modified Culture Technique for Burn Wound Coverage: A Case Report and Long-Term Follow-Up.","authors":"Wayne George Kleintjes, Tarryn Kay Prinsloo","doi":"10.3390/ebj6020029","DOIUrl":"10.3390/ebj6020029","url":null,"abstract":"Cultured epidermal autografts (CEAs) serve as an alternative permanent skin replacement, though high costs often limit their use in resource-constrained settings and to life-saving cases. This case report presents the first documented cosmetic application of a modified CEA technique in a bodybuilder, demonstrating favorable aesthetic outcomes. A 28-year-old Black male with a 20% total body surface area burn sustained in a domestic fire exhibited superficial and deep partial-thickness burns to the face, arms, torso, and feet. Refusing grafts from visible donor sites, treatment using a low-cost modified CEA approach was employed to minimize donor site morbidity. Keratinocytes harvested from a groin biopsy were cultured on Cutimed Sorbact® (Essity AB, BSN Medical (Pty) Ltd., Pinetown, RSA) dressings with autogenous plasma and hydrogel supplementation and incubated at 37 °C for two weeks. Xenografts provided temporary coverage before CEA transplantation. Graft take was 85%, with minor (15%) loss at 21 days, requiring small autograft coverage. At two months, the Vancouver Scar Scale score was 4, indicating optimal pigmentation, smoother texture, and minimal scarring. These findings align with limited studies on CEAs for cosmetic applications, suggesting this cost-effective technique may broaden the scope of CEAs beyond life-saving interventions to include aesthetic reconstruction, reducing both donor site morbidity and scarring.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 1

European burn journal Pub Date : 2025-06-03 DOI: 10.3390/ebj6020031

Maria Fueth, Simon Bausen, Sonja Verena Schmidt, Felix Reinkemeier, Marius Drysch, Yonca Steubing, Jannik Hinzmann, Marcus Lehnhardt, Elisabete Macedo Santos, Christoph Wallner

{"title":"Explosion-Related Polytrauma from Illicit Pyrotechnics: Two Case Reports and a Public Health Perspective.","authors":"Maria Fueth, Simon Bausen, Sonja Verena Schmidt, Felix Reinkemeier, Marius Drysch, Yonca Steubing, Jannik Hinzmann, Marcus Lehnhardt, Elisabete Macedo Santos, Christoph Wallner","doi":"10.3390/ebj6020031","DOIUrl":"10.3390/ebj6020031","url":null,"abstract":"Firework-related injuries remain a serious public health issue in Germany, especially during New Year's Eve. While many injuries are minor, the misuse of illegal or homemade fireworks can cause severe trauma resembling military combat injuries and can heavily burden emergency services. Notably, injury rates declined during the COVID-19 firework bans, underscoring the impact of preventive measures. We report two cases of young males with severe injuries from illicit fireworks. The first is a case of a 16-year-old that detonated an illegal Polish firework ball bomb, sustaining 9% total body surface area (TBSA) burns (second- to third-degree), hand fractures, compartment syndrome of the hand, and soft-tissue trauma. He underwent multiple surgeries, including fasciotomy, osteosynthesis, and skin grafting. The other case presented is a 19-year-old man who was injured by a homemade device made of bundled firecrackers, suffering deep facial and bilateral hand burns. He required prolonged ventilation, surgical debridement, and treatment with Kerecis® fish skin and Epicite® dressings. Both required intensive ICU care, interdisciplinary management, and lengthy rehabilitation. Total hospital costs amounted to €58,459.52 and €94,230.23, respectively, as calculated according to the standardized German DRG. These cases illustrate the devastating impact of illegal fireworks. The devastating consequences of explosive trauma are often difficult to treat and may lead to long-term functional and psychological impairments. Prevention through public education, stricter regulations, and preparedness is essential. Pandemic-era injury reductions support sustained policy efforts.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From Data to Decisions: Leveraging Retrieval-Augmented Generation to Balance Citation Bias in Burn Management Literature. 从数据到决策：利用检索增强生成来平衡烧伤管理文献中的引文偏倚。

IF 1

European burn journal Pub Date : 2025-06-02 DOI: 10.3390/ebj6020028

Ariana Genovese, Srinivasagam Prabha, Sahar Borna, Cesar A Gomez-Cabello, Syed Ali Haider, Maissa Trabilsy, Cui Tao, Antonio Jorge Forte

{"title":"From Data to Decisions: Leveraging Retrieval-Augmented Generation to Balance Citation Bias in Burn Management Literature.","authors":"Ariana Genovese, Srinivasagam Prabha, Sahar Borna, Cesar A Gomez-Cabello, Syed Ali Haider, Maissa Trabilsy, Cui Tao, Antonio Jorge Forte","doi":"10.3390/ebj6020028","DOIUrl":"10.3390/ebj6020028","url":null,"abstract":"(1) Burn injuries demand multidisciplinary, evidence-based care, yet the extensive literature complicates timely decision making. Retrieval-augmented generation (RAG) synthesizes research while addressing inaccuracies in pretrained models. However, citation bias in sourcing for RAG often prioritizes highly cited studies, overlooking less-cited but valuable research. This study examines RAG's performance in burn management, comparing citation levels to enhance evidence synthesis, reduce selection bias, and guide decisions. (2) Two burn management datasets were assembled: 30 highly cited (mean: 303) and 30 less-cited (mean: 21). The Gemini-1.0-Pro-002 RAG model addressed 30 questions, ranging from foundational principles to advanced surgical approaches. Responses were evaluated for accuracy (5-point scale), readability (Flesch-Kincaid metrics), and response time with Wilcoxon rank sum tests (p < 0.05). (3) RAG achieved comparable accuracy (4.6 vs. 4.2, p = 0.49), readability (Flesch Reading Ease: 42.8 vs. 46.5, p = 0.26; Grade Level: 9.9 vs. 9.5, p = 0.29), and response time (2.8 vs. 2.5 s, p = 0.39) for the highly and less-cited datasets. (4) Less-cited research performed similarly to highly cited sources. This equivalence broadens clinicians' access to novel, diverse insights without sacrificing quality. As plastic surgery evolves, RAG's inclusive approach fosters innovation, improves patient care, and reduces cognitive burden by integrating underutilized studies. Embracing RAG could propel the field toward dynamic, forward-thinking care.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Face and Neck Burns on Respiratory Complications and Mortality. 面部和颈部烧伤对呼吸系统并发症和死亡率的影响。

IF 1

European burn journal Pub Date : 2025-05-22 DOI: 10.3390/ebj6020027

Rares-Adrian Giurgiu, Eliza-Maria Bordeanu-Diaconescu, Andreea Grosu-Bularda, Adrian Frunza, Sabina Grama, Raducu-Andrei Costache, Carina-Ioana Cristescu, Tiberiu-Paul Neagu, Ioan Lascar, Cristian-Sorin Hariga

{"title":"The Impact of Face and Neck Burns on Respiratory Complications and Mortality.","authors":"Rares-Adrian Giurgiu, Eliza-Maria Bordeanu-Diaconescu, Andreea Grosu-Bularda, Adrian Frunza, Sabina Grama, Raducu-Andrei Costache, Carina-Ioana Cristescu, Tiberiu-Paul Neagu, Ioan Lascar, Cristian-Sorin Hariga","doi":"10.3390/ebj6020027","DOIUrl":"10.3390/ebj6020027","url":null,"abstract":"Face and neck burns present significant clinical challenges due to their proximity to the airway, predisposing patients to inhalation injuries and subsequent respiratory complications. In our cohort of 206 patients, facial and neck burns were associated with a markedly higher incidence of inhalation injury (34.8% vs. 2.8%), necessitating more frequent endotracheal intubation (51.9% vs. 14.1%). Furthermore, respiratory infections were significantly more common in patients with facial and neck burns (26.7% vs. 7%, p < 0.001), with respiratory secretion cultures revealing a predominance of Pseudomonas aeruginosa (39.58%), Acinetobacter baumanii (18.75%), and Klebsiella pneumoniae (6.25%). In contrast, patients without facial and neck burns primarily exhibited Pseudomonas aeruginosa (50%) in their cultures. These complications translated into a significantly increased mortality rate in patients with facial and neck burns (31.1% vs. 12.7%), with a reduced mean survival period (66.7 days vs. 84.3 days) and a 2.8-fold increase in the hazard of mortality. Additionally, older age emerged as a significant determinant for the development of respiratory infections. Multivariable model regression analysis revealed that only TBSA remained a consistent and independent predictor for adverse respiratory outcomes and increased mortality, while face and neck burns are more causally associated with TBSA.","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0