Felix J Klimitz, Martin Aman, Hubert Neubauer, Annette Stolle, Hans Ziegenthaler, Tobias Niederegger, Adriana C Panayi, Gabriel Hundeshagen, Ulrich Kneser, Leila Harhaus
{"title":"创伤后应激障碍(PTSD)与严重烧伤后皮肤症状负担增加有关:多中心前瞻性队列的亚组分析","authors":"Felix J Klimitz, Martin Aman, Hubert Neubauer, Annette Stolle, Hans Ziegenthaler, Tobias Niederegger, Adriana C Panayi, Gabriel Hundeshagen, Ulrich Kneser, Leila Harhaus","doi":"10.3390/ebj6030043","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Severe burn injuries often lead to lasting physical and psychological consequences. Post-traumatic stress disorder (PTSD) is common among burn survivors and may be influenced by persistent somatic complaints. This study examined whether PTSD is associated with a higher burden of physical symptoms during and after inpatient rehabilitation.</p><p><strong>Methods: </strong>We conducted a subgroup analysis of a multicenter prospective cohort study involving 103 adult burn patients in inpatient rehabilitation. Based on Impact of Event Scale-Revised (IES-R) scores and clinical evaluation, patients were grouped as PTSD (n = 43) or No PTSD (n = 60). Physical symptoms assessed included skin dryness (xerosis), temperature sensitivity (cold/heat), numbness, skin tightness, and increased sweating.</p><p><strong>Results: </strong>Patients with PTSD reported significantly more physical symptoms at follow-up than those without PTSD: xerosis (74% vs. 50%, <i>p</i> = 0.03), cold sensitivity (61% vs. 35%, <i>p</i> = 0.02), heat sensitivity (63% vs. 39%, <i>p</i> = 0.03), numbness (63% vs. 33%, <i>p</i> = 0.006), skin tightness (82% vs. 52%, <i>p</i> = 0.004), and sweating (45% vs. 19%, <i>p</i> = 0.01). PTSD patients also had more severe burns, reflected in higher full-thickness TBSA (2% vs. 0%, <i>p</i> = 0.03) and elevated ABSI scores (median 6 vs. 5, <i>p</i> = 0.04).</p><p><strong>Conclusion: </strong>PTSD is associated with a higher and more persistent burden of physical skin symptoms after severe burns. These findings underscore the importance of early PTSD screening and integrated psychological-somatic rehabilitation to improve long-term recovery and quality of life.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"6 3","pages":""},"PeriodicalIF":1.2000,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372007/pdf/","citationCount":"0","resultStr":"{\"title\":\"Post-Traumatic Stress Disorder (PTSD) Is Associated with Increased Physical Skin Symptom Burden Following Severe Burn Injuries: Subgroup Analysis of a Multicenter Prospective Cohort.\",\"authors\":\"Felix J Klimitz, Martin Aman, Hubert Neubauer, Annette Stolle, Hans Ziegenthaler, Tobias Niederegger, Adriana C Panayi, Gabriel Hundeshagen, Ulrich Kneser, Leila Harhaus\",\"doi\":\"10.3390/ebj6030043\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Severe burn injuries often lead to lasting physical and psychological consequences. Post-traumatic stress disorder (PTSD) is common among burn survivors and may be influenced by persistent somatic complaints. This study examined whether PTSD is associated with a higher burden of physical symptoms during and after inpatient rehabilitation.</p><p><strong>Methods: </strong>We conducted a subgroup analysis of a multicenter prospective cohort study involving 103 adult burn patients in inpatient rehabilitation. Based on Impact of Event Scale-Revised (IES-R) scores and clinical evaluation, patients were grouped as PTSD (n = 43) or No PTSD (n = 60). Physical symptoms assessed included skin dryness (xerosis), temperature sensitivity (cold/heat), numbness, skin tightness, and increased sweating.</p><p><strong>Results: </strong>Patients with PTSD reported significantly more physical symptoms at follow-up than those without PTSD: xerosis (74% vs. 50%, <i>p</i> = 0.03), cold sensitivity (61% vs. 35%, <i>p</i> = 0.02), heat sensitivity (63% vs. 39%, <i>p</i> = 0.03), numbness (63% vs. 33%, <i>p</i> = 0.006), skin tightness (82% vs. 52%, <i>p</i> = 0.004), and sweating (45% vs. 19%, <i>p</i> = 0.01). PTSD patients also had more severe burns, reflected in higher full-thickness TBSA (2% vs. 0%, <i>p</i> = 0.03) and elevated ABSI scores (median 6 vs. 5, <i>p</i> = 0.04).</p><p><strong>Conclusion: </strong>PTSD is associated with a higher and more persistent burden of physical skin symptoms after severe burns. These findings underscore the importance of early PTSD screening and integrated psychological-somatic rehabilitation to improve long-term recovery and quality of life.</p>\",\"PeriodicalId\":72961,\"journal\":{\"name\":\"European burn journal\",\"volume\":\"6 3\",\"pages\":\"\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2025-08-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372007/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European burn journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3390/ebj6030043\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CRITICAL CARE MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European burn journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/ebj6030043","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
Post-Traumatic Stress Disorder (PTSD) Is Associated with Increased Physical Skin Symptom Burden Following Severe Burn Injuries: Subgroup Analysis of a Multicenter Prospective Cohort.
Background: Severe burn injuries often lead to lasting physical and psychological consequences. Post-traumatic stress disorder (PTSD) is common among burn survivors and may be influenced by persistent somatic complaints. This study examined whether PTSD is associated with a higher burden of physical symptoms during and after inpatient rehabilitation.
Methods: We conducted a subgroup analysis of a multicenter prospective cohort study involving 103 adult burn patients in inpatient rehabilitation. Based on Impact of Event Scale-Revised (IES-R) scores and clinical evaluation, patients were grouped as PTSD (n = 43) or No PTSD (n = 60). Physical symptoms assessed included skin dryness (xerosis), temperature sensitivity (cold/heat), numbness, skin tightness, and increased sweating.
Results: Patients with PTSD reported significantly more physical symptoms at follow-up than those without PTSD: xerosis (74% vs. 50%, p = 0.03), cold sensitivity (61% vs. 35%, p = 0.02), heat sensitivity (63% vs. 39%, p = 0.03), numbness (63% vs. 33%, p = 0.006), skin tightness (82% vs. 52%, p = 0.004), and sweating (45% vs. 19%, p = 0.01). PTSD patients also had more severe burns, reflected in higher full-thickness TBSA (2% vs. 0%, p = 0.03) and elevated ABSI scores (median 6 vs. 5, p = 0.04).
Conclusion: PTSD is associated with a higher and more persistent burden of physical skin symptoms after severe burns. These findings underscore the importance of early PTSD screening and integrated psychological-somatic rehabilitation to improve long-term recovery and quality of life.