Yamile Montecinos-Rodríguez, Francisco J Torres-Santana, Noureddine Lakouari, Lorena Díaz-González
{"title":"Automated Classification of Second- and Third-Degree Burn Images Using Convolutional Neural Networks.","authors":"Yamile Montecinos-Rodríguez, Francisco J Torres-Santana, Noureddine Lakouari, Lorena Díaz-González","doi":"10.3390/ebj7020033","DOIUrl":"10.3390/ebj7020033","url":null,"abstract":"<p><strong>Background: </strong>Burn severity assessment is clinically relevant and often requires timely decision-making. Visual classification of second- and third-degree burns remains subjective and prone to observer variability.</p><p><strong>Methods: </strong>This study aimed to develop and evaluate a deep learning model for the automatic classification of second- and third-degree burn images. A dataset of clinical burn images from a private wound care clinic was used to train a convolutional neural network. Hyperparameter optimization and color channel sensitivity analysis were performed to identify the optimal model configuration. Model performance was evaluated using standard classification metrics on training, validation, and independent test datasets, and results were compared with transfer learning approaches.</p><p><strong>Results: </strong>The best performance was achieved using a compact model trained exclusively with the green color channel, obtaining an accuracy of 0.94, precision of 0.96, recall of 0.92, and an F1-score of 0.94 on the independent test set. This model outperformed more complex transfer learning approaches while reducing computational complexity.</p><p><strong>Conclusions: </strong>These findings indicate that using only the green color channel enables efficient and accurate burn classification. The proposed model was also integrated into a graphical user interface, supporting its potential application in clinical and educational environments.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"7 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13297944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148320957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Quentin Isaacs, Chrysis Sofianos, Adelin Muganza, Brian Brummer
{"title":"A Single-Centre Review of Outcomes of Delayed Admission to a Burns Unit.","authors":"Quentin Isaacs, Chrysis Sofianos, Adelin Muganza, Brian Brummer","doi":"10.3390/ebj7020032","DOIUrl":"10.3390/ebj7020032","url":null,"abstract":"<p><p><b>Background:</b> Timely admission to a specialised burn unit is considered crucial for optimising outcomes in burn patients. However, the impact of delayed admission on hospital length of stay and clinical outcomes remains unclear, particularly in resource-constrained settings such as South Africa. This retrospective study aimed to determine whether admission to a burn unit more than 24 h after injury was associated with increased length of stay, sepsis, or mortality. <b>Methods:</b> A retrospective case-audit study was conducted at the Chris Hani Baragwanath Academic Hospital Adult Burn Unit, Johannesburg, from January 2018 to December 2022. Patients were categorised into early (≤24 h) and delayed (>24 h) admission groups. The primary outcome was length of stay; secondary outcomes included sepsis incidence and in-hospital mortality. <b>Results:</b> A total of 123 files were analysed; 71 (58%) were admitted within 24 h. The median length of stay was 14 days, with no statistical difference between the two groups (<i>p</i> = 0.7). The overall mortality rate was 13%, with 68% occurring in the early admission group. Sepsis occurred in 27% of patients. Multivariate analysis revealed that early admission was independently associated with longer length of stay. <b>Conclusions:</b> In this single-centre retrospective case note audit with a limited sample size and significant risk of selection bias, delayed admission to a burn unit was not associated with increased length of stay, mortality, or sepsis. However, these findings should be considered preliminary and require confirmation in larger, prospective studies. The higher rate of surgical intervention in the delayed admission group warrants further investigation.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"7 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13297935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148320948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hongyu Tang, Shenjing Yu, Rui Zhang, Zheng Zhu, Li Gui
{"title":"Bridging the Evidence-Practice Gap in Early Burn Injury Care: A Comprehensive Evidence Synthesis of Global Guidelines, Consensus, and Systematic Reviews for Resource-Limited Settings.","authors":"Hongyu Tang, Shenjing Yu, Rui Zhang, Zheng Zhu, Li Gui","doi":"10.3390/ebj7020034","DOIUrl":"10.3390/ebj7020034","url":null,"abstract":"<p><strong>Background: </strong>Early management of adult burn injuries in resource-constrained environments-such as battlefields and primary care facilities-remains hindered by the absence of standardized, evidence-based protocols. This study aimed to systematically synthesize existing evidence and develop an integrated framework of actionable recommendations to optimize prehospital and early emergency care.</p><p><strong>Methods: </strong>A comprehensive evidence synthesis was conducted across 14 international and domestic bibliographic databases and authoritative repositories. Eligible sources included clinical practice guidelines, expert consensus statements, evidence summaries, and systematic reviews. Literature quality was appraised using validated instruments, and best-practice recommendations were extracted and thematically synthesized across the continuum of early burn care.</p><p><strong>Results: </strong>Fifty-nine high-quality studies yielded 77 recommendations across 13 domains, spanning from scene safety and burn process cessation through airway, breathing, and circulatory management to wound care, infection control, and transfer preparation. An integrated, context-adaptive framework was established to guide resource-calibrated interventions rather than rigid protocol adherence.</p><p><strong>Conclusions: </strong>These findings provide tiered guidance for frontline healthcare providers and inform the development of emergency care standards in resource-limited settings. Future research should prioritize field validation and contextual implementation to address barriers to evidence translation and enhance real-world applicability.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"7 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13298258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148321004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joshua P Kronenfeld, Louis R Pizano, Ray I Gonzalez, Joyce I Kaufman, Shevonne Satahoo, Carl I Schulman
{"title":"Simulation Enhances Resident Preparedness Using Skin Cell Suspension Autograft.","authors":"Joshua P Kronenfeld, Louis R Pizano, Ray I Gonzalez, Joyce I Kaufman, Shevonne Satahoo, Carl I Schulman","doi":"10.3390/ebj7020031","DOIUrl":"10.3390/ebj7020031","url":null,"abstract":"<p><strong>Objective: </strong>Surgical simulation has been shown to improve efficiency, performance, and time to mastery for complicated procedures, but simulation training is not always considered when introducing new devices or products. As part of a performance improvement project, we sought to design and evaluate simulation training for the skin cell suspension autograft (SCSA) with surgery residents during their Burn rotation.</p><p><strong>Methods: </strong>Residents were asked to read instructional materials and watch training videos before coming into the simulation lab for the training session supervised by a Burn surgeon. A qualitative survey was designed and administered after completion of the rotation.</p><p><strong>Results: </strong>Twelve residents have completed the training thus far. Their feedback from the training session was rated on a five-point Likert scale and indicated that the simulation activity was an appropriate length (4.6/5.0), was thorough (4.8/5.0), and led to more confidence (4.4/5.0) and less apprehension (4.4/5.0) when performing the procedure on live patients. This was followed by their use of the product in the operating room with complete success.</p><p><strong>Conclusions: </strong>The novel SCSA training shows great promise for improving the confidence and performance of surgical residents. This could allow for a shorter time for residents to become independent in its use, thereby allowing for increased operative efficiency with the opportunity to significantly improve trainee expertise.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"7 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13214940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadia Depetris, Alette E E de Jong, Clemens Schiestl, Fredrik Huss, Gregoire Bondu, Jill Meirte, Jyrki Vuola, Luís Cabral, Moustafa Elmasry, Raluca Tatar Bulea, Robert Zajíček, Stian Almeland, Yvonne Wilson
{"title":"The 4th Educational Course of the European Burns Association (EBA).","authors":"Nadia Depetris, Alette E E de Jong, Clemens Schiestl, Fredrik Huss, Gregoire Bondu, Jill Meirte, Jyrki Vuola, Luís Cabral, Moustafa Elmasry, Raluca Tatar Bulea, Robert Zajíček, Stian Almeland, Yvonne Wilson","doi":"10.3390/ebj7020030","DOIUrl":"10.3390/ebj7020030","url":null,"abstract":"<p><p>Abstracts of the plenary sessions, workshops, and poster presentations of the 4th EBA Educational Course in Bucharest, Romania, 15-16 May 2026.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"7 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13214679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Japanese Consensus Document on NexoBrid<sup>®</sup>, a Burn Eschar Removal Agent.","authors":"Hajime Matsumura, Takahiro Ueda, Rei Ogawa, Yasuhiko Kaita, Hiroyuki Sakurai, Kazutaka Soejima, Junichi Sasaki","doi":"10.3390/ebj7020029","DOIUrl":"10.3390/ebj7020029","url":null,"abstract":"<p><strong>Background: </strong>NexoBrid<sup>®</sup> (NXB), an enzymatic debridement agent approved in Japan in 2022, provides a less invasive alternative to surgical excision for burn treatment. However, its optimal therapeutic benefit depends on appropriate patient selection and proper application technique. Existing international consensus documents are not fully applicable to clinical practice in Japan because of differences in available devices and drugs. Therefore, a Japan-specific consensus document was developed by a panel of seven Japanese burn experts, including four plastic surgeons and three emergency physicians.</p><p><strong>Methods: </strong>A questionnaire-based survey was conducted using the Delphi method to achieve expert consensus. Consensus was defined as agreement by at least 80% of committee members for each statement. A total of 27 statements were evaluated over two rounds.</p><p><strong>Results: </strong>Consensus was achieved for 20 of 27 statements (74.1%) in the first round and for 21 of 27 statements (77.8%) in the second round. The finalised statements were organised into seven categories according to their attributes: indications, pain management, application timing, application technique, post-application wound care, skin grafting, and scarring/aesthetic outcomes.</p><p><strong>Conclusions: </strong>This consensus document integrates the opinions of plastic surgeons and emergency physicians in Japan, while also incorporating relevant international perspectives, to provide practical guidance on the use of NXB for burn treatment. It is intended to improve the quality of burn care by clarifying efficacy, safety, and precautions associated with NXB use. These recommendations should be updated as further clinical experience accumulates.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"7 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13214741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148038372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jill Meirte, Stefania Anna Simone, Sabrina Belemkasser, Jonathan Bayuo
{"title":"Recommendations on Sexuality and Intimacy After Burn Injuries.","authors":"Jill Meirte, Stefania Anna Simone, Sabrina Belemkasser, Jonathan Bayuo","doi":"10.3390/ebj7020026","DOIUrl":"10.3390/ebj7020026","url":null,"abstract":"<p><strong>Background: </strong>Burn injuries profoundly impact the survivors' physical, psychological and social well-being, with sexuality, intimacy and body image remaining among the most disrupted yet least addressed areas of rehabilitation. Limited professional training, social discomfort, and a lack of clinical guidance contribute to these unmet needs. Recognizing sexuality as an essential part of health, this interdisciplinary project developed evidence-informed recommendations and communication tools to support both burn survivors and healthcare professionals in discussing intimacy, sexuality, and body image after burn injury.</p><p><strong>Methods: </strong>An interdisciplinary expert group conducted a narrative literature review, supplemented with grey literature and lived experience resources. These insights informed two practical tools: a poster for healthcare professionals and burn centers, and a patient-focused brochure. Both underwent iterative refinement through multicultural feedback from patients and professionals across Europe, Asia and Africa, followed by final validation during an interdisciplinary workshop at the 2025 European Burns Association (EBA) Conference.</p><p><strong>Results: </strong>The literature indicated that burn injuries affect sexuality and body image through interacting physiological, psychological, sensory, relational, and sociocultural factors. Common challenges included reduced desire, anxiety, fear of rejection, altered self-perception, and discomfort initiating conversations about intimacy. Professionals reported limited training, insufficient privacy and cultural barriers.</p><p><strong>Conclusions: </strong>The developed tools and these recommendations aim to normalize dialog, support proactive screening, and promote culturally sensitive patient-centered burn rehabilitation. Embedding sexuality and intimacy within burn care requires ongoing professional training and the identification of dedicated resource persons within each team.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"7 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13214789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicole Lee, Ascanio Tridente, Niall Martin, Odhran Shelley, On Behalf Of The Uk Working Group For Enzymatic Debridement
{"title":"The UK Consensus Statement for the Use of Enzymatic Debridement in Burn Care.","authors":"Nicole Lee, Ascanio Tridente, Niall Martin, Odhran Shelley, On Behalf Of The Uk Working Group For Enzymatic Debridement","doi":"10.3390/ebj7020027","DOIUrl":"10.3390/ebj7020027","url":null,"abstract":"<p><p><b>Background</b>: Over the past ten years, enzymatic debridement has been used more often to treat burn injuries in the UK and Europe. Even though it is increasingly adopted, there are still major differences in how it is practiced. These differences are mainly due to varying levels of professional experience, differences in the interpretation of available evidence, and concerns about safety and effectiveness. <b>Methods</b>: To help resolve these issues and create more consistent care, the UK National Consensus Working Group was formed. This group brought together burn care experts from different backgrounds to review current methods, published research, and consensus guidelines. They used a structured approach that included educational webinars, a thorough review of the literature, and a national survey using the Delphi method to gather expert opinions and real-world experiences. <b>Results</b>: As a result of this process, the UK Consensus Statement for the Use of Enzymatic Debridement in Burn Care was created and officially approved after extensive consultation at national meetings. The main recommendations focus on safely and effectively including enzymatic debridement in burn care, the need for clear procedures, and identifying areas where further research is needed, such as patient outcomes and dressing methods. <b>Conclusions</b>: The goal of this consensus statement is to unify practices, guide future research, and support ongoing improvements in burn care throughout the UK.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"7 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13214822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148038060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rahel Kassa Bayou, Meheret Befekadu Demmissie, Bethelhem Kassa Bayou, Laura Pompermaier, Hanna Yemane Berhane, Bacha Mirkena Dhabi
{"title":"Predictors of Mortality in Burn Patients at Selected Tertiary Public Hospitals in Addis Ababa, Ethiopia: A Two-Year Retrospective Study.","authors":"Rahel Kassa Bayou, Meheret Befekadu Demmissie, Bethelhem Kassa Bayou, Laura Pompermaier, Hanna Yemane Berhane, Bacha Mirkena Dhabi","doi":"10.3390/ebj7020028","DOIUrl":"10.3390/ebj7020028","url":null,"abstract":"<p><p><b>Background:</b> Burn injuries are a major cause of morbidity and mortality in low- and middle-income countries, yet remain underreported due to limited data systems. This study describes the epidemiology of burn patients admitted to two major burn centers in Addis Ababa, Ethiopia, and identifies predictors of in-hospital mortality. <b>Methods:</b> A cross-sectional study was conducted among patients with new burn injuries admitted between 1 September 2021, and 1 November 2023, at the Addis Ababa Burn, Emergency, and Trauma Center (AaBET) and Yekatit 12 Medical College (Y12MC) hospitals. Data were extracted from medical records. Descriptive statistics summarized patient characteristics, and binary logistic regression with multivariable analysis identified factors associated with in-hospital mortality using adjusted odds ratios (AORs) and 95% confidence intervals (CIs). <b>Results:</b> Chart completeness was 96.2%. Among 800 patients, 57% were female, with a median age of 18 years (range: 0-89); approximately 80% were under 30 years. Scalds were the leading cause (49.1%). In-hospital mortality was 8.5% (95% CI: 6.5-10.4). Significant predictors included inhalation injury (AOR 6.53), TBSA ≥ 15% (AOR 3.33), deep burns (AOR 1.96), and ICU admission (AOR 14.42). <b>Conclusions:</b> In-hospital mortality was moderate, disproportionately affecting children and young adults, underscoring the need to strengthen critical care and management of severe burns.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"7 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13214742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148038296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elad Zvi, Melissa Neely, Louise Higgins, Maja Garcia, Melinda Pacquola, Eldho Paul, Alex Padiglione, Heather Cleland, Cheng Hean Lo
{"title":"The Efficacy of UV-C Disinfection in Decreasing Hospital-Acquired Infections and Bioburden in an Adult Burns Service.","authors":"Elad Zvi, Melissa Neely, Louise Higgins, Maja Garcia, Melinda Pacquola, Eldho Paul, Alex Padiglione, Heather Cleland, Cheng Hean Lo","doi":"10.3390/ebj7020025","DOIUrl":"10.3390/ebj7020025","url":null,"abstract":"<p><strong>Background: </strong>Burn patients are highly susceptible to hospital-acquired infections (HAIs), and contaminated near-patient surfaces can act as reservoirs for multidrug-resistant organisms (MROs). Ultraviolet-C (UV-C) room disinfection is increasingly used as an adjunct to manual cleaning, but real-world data in adult burns settings remain limited.</p><p><strong>Methods: </strong>We evaluated adjunctive UV-C disinfection in a tertiary adult trauma and burns surgical ward using a two-part observational design. Part A compares MRO-related HAI incidence before UV-C implementation (12 May 2015-11 May 2020; retrospective) with its incidence after implementation (14 July 2020-13 July 2021; prospective). Part B is a matched pre/post environmental sampling study (December 2022-December 2024) of 44 vacant rooms. Paired swabs from a single randomised high-touch surface per room were collected immediately before and after UV-C disinfection and processed by an independent laboratory.</p><p><strong>Results: </strong>Part A included 7589 admissions (6415 before-UV-C; 1174 after-UV-C) with 2728 UV-C cycles delivered after implementation. MRO-related HAI incidence decreased from 18.3 to 10.2 per 1000 bed-days (<i>p</i> < 0.01). In Part B, the proportion of swabs with <10 CFU increased after UV-C disinfection (66% vs. 50%, <i>p</i> = 0.02). Among swabs with non-negligible baseline contamination and excluding increases, the median CFU reduction was 97% (SD 12%; <i>p</i> < 0.001), with no significant differences in reduction across sampled surface types.</p><p><strong>Conclusion: </strong>In an adult burns surgical ward, adjunctive UV-C disinfection was associated with reduced MRO-related HAI incidence and a substantial reduction in environmental bioburden on high-touch surfaces. These real-world findings support UV-C as a feasible adjunct to standard cleaning in high-risk burn services and inform future controlled evaluations.</p>","PeriodicalId":72961,"journal":{"name":"European burn journal","volume":"7 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13214841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148038055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}