Epidemiolgia (Basel, Switzerland)最新文献

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Conceptualization of Depression among Medical Students and Its Differences during Medical Education. 医学生对抑郁症的认识及其在医学教育过程中的差异。
Epidemiolgia (Basel, Switzerland) Pub Date : 2024-09-09 DOI: 10.3390/epidemiologia5030042
Santi Arana-Ballestar, Ricardo Campos-Ródenas, Beatriz Olaya, Javier Santabárbara
{"title":"Conceptualization of Depression among Medical Students and Its Differences during Medical Education.","authors":"Santi Arana-Ballestar, Ricardo Campos-Ródenas, Beatriz Olaya, Javier Santabárbara","doi":"10.3390/epidemiologia5030042","DOIUrl":"10.3390/epidemiologia5030042","url":null,"abstract":"<p><p>The definition of mental disorders has been traditionally a matter of discussion, and it has relevant implications in research and healthcare. Our aim was to explore the conceptualization medical students have of depression and to determine differences across academic years. The Maudsley Attitudes Questionnaire was adapted through a double translation, double back-translation and a preliminary validation, obtaining a Spanish edition. All students of the Faculty of Medicine of the University of Zaragoza and doctors who graduated from this University in 2020 were invited to answer the online questionnaire, and we received 222 answers (response rate: 15.2%). The results were compared by years and levels of education using an ANOVA. The social realist, behavioral, biological, cognitive and psychodynamic models were the most endorsed. The psychodynamic and nihilist models were less embraced by students in later educational years. These students also reported greater confidence in their understanding of depression and of its biological, cognitive and behavioral models. In conclusion, the conceptualization of depression among medical students is complex and multidimensional, and appears to be similar across different years of education. In later years, we found less support for the psychodynamic model, increased confidence in psychiatry and greater ease in handling the concepts of its leading models.</p>","PeriodicalId":72944,"journal":{"name":"Epidemiolgia (Basel, Switzerland)","volume":"5 3","pages":"605-617"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupational Health Problems among Cambodian Dentists: A Cross-Sectional Study. 柬埔寨牙医的职业健康问题:横断面研究
Epidemiolgia (Basel, Switzerland) Pub Date : 2024-09-05 DOI: 10.3390/epidemiologia5030041
Rodrigo Mariño, Rithvitou Horn, Moniroth Seat, Konitha Hong, Sokpheakta Hen
{"title":"Occupational Health Problems among Cambodian Dentists: A Cross-Sectional Study.","authors":"Rodrigo Mariño, Rithvitou Horn, Moniroth Seat, Konitha Hong, Sokpheakta Hen","doi":"10.3390/epidemiologia5030041","DOIUrl":"10.3390/epidemiologia5030041","url":null,"abstract":"<p><p>Dental practitioners, as part of their work, are exposed to a variety of hazards. This highlights the ongoing need for attention to occupational health in the dental field. A cross-sectional study was organised to investigate the range, prevalence, and associated factors for occupational health problems related to dental practice among Cambodian dentists. Participants underwent a face-to-face interview to explore dentists work-related health problems; 106 Cambodian dentists participated in this study, of which 68.9% were male. Ages ranged from 29 to 71 years, averaging 36.1 years, with the majority (77.4%) in the 29-40 age group. They had 5 to 18 years of practice experience, and worked an average of 52.2 h per week. Commonly reported health issues included back pain (88.7%), headaches (81.1%), shoulder pain (78.3%), arm/hand pain (57.5%), and eye problems (48.1%). Additionally, 38.7% of participants felt stressed and 19.8% depressed. Some reported suicidal thoughts and taking medication for depression. Despite these challenges, 91.5% enjoyed practicing dentistry. These findings highlight the need for interventions and strategies to address the physical and mental well-being of Cambodian dentists. By addressing these issues, steps can be taken to enhance the working conditions and professional satisfaction of dental professionals, ultimately benefiting both the practitioners and their patients.</p>","PeriodicalId":72944,"journal":{"name":"Epidemiolgia (Basel, Switzerland)","volume":"5 3","pages":"592-604"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in Mortality Due to Stroke in South America between 1990 and 2019. 1990 年至 2019 年南美洲中风死亡率趋势。
Epidemiolgia (Basel, Switzerland) Pub Date : 2024-09-03 DOI: 10.3390/epidemiologia5030040
Alexandre Castelo Branco Araujo, Orivaldo Florencio de Souza, Filomena Euridice Carvalho de Alencar, Betina Bolina Kersanach, Victor Lopes Feitosa, Julia Silva Cesar Mozzer, Vinicius Andreata Brandão, Gabriel Marim Roni, Carlos Bandeira de Mello Monteiro, Luiz Carlos de Abreu
{"title":"Trends in Mortality Due to Stroke in South America between 1990 and 2019.","authors":"Alexandre Castelo Branco Araujo, Orivaldo Florencio de Souza, Filomena Euridice Carvalho de Alencar, Betina Bolina Kersanach, Victor Lopes Feitosa, Julia Silva Cesar Mozzer, Vinicius Andreata Brandão, Gabriel Marim Roni, Carlos Bandeira de Mello Monteiro, Luiz Carlos de Abreu","doi":"10.3390/epidemiologia5030040","DOIUrl":"10.3390/epidemiologia5030040","url":null,"abstract":"<p><p>Stroke is the second leading cause of death and disability in Latin America; however, few epidemiological studies have been conducted in South America. An observational study was conducted to analyze trends in stroke mortality in South American (SA) countries. Age-standardized mortality rates and proportional mortality due to stroke in the populations of SA countries between 1990 and 2019 were assessed by extracting data from the Global Burden of Disease 2019 study. Joinpoint regression models were employed to identify trends in the annual percentage change in mortality rates for each segment. Considering the data collected over the 30 years that were studied, the age-standardized stroke mortality trend decreased in Argentina (-1.6%), Uruguay (-0.6%), Brazil (-0.5%), Guyana (-0.5%), and Bolivia (-0.4%), while Venezuela (+1.6%) and Suriname (+1.0%) showed an increasing trend. The proportional stroke mortality trend decreased in Argentina (-1.7%), Paraguay (-0.9%), Uruguay (-0.7%), Guyana (-0.7%), Brazil (-0.5%), and Chile (-0.5%), whereas Bolivia (+1.0%), Suriname (+0.6%), and Peru (+0.4%) exhibited an increasing trend. The trends in stroke mortality between 1990 and 2019 demonstrated considerable variability. While most SA countries experienced significant decreases in stroke mortality trends, Venezuela and Suriname showed increases in age-standardized mortality rates, and Bolivia, Suriname, and Peru exhibited increases in proportional mortality rates. No decreasing stroke mortality trend was observed in the segment after the last joinpoint, highlighting the need for improvement in prevention and treatment.</p>","PeriodicalId":72944,"journal":{"name":"Epidemiolgia (Basel, Switzerland)","volume":"5 3","pages":"581-591"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimising Clinical Epidemiology in Disease Outbreaks: Analysis of ISARIC-WHO COVID-19 Case Report Form Utilisation. 优化疾病爆发中的临床流行病学:分析 ISARIC-WHO COVID-19 病例报告表的使用情况。
Epidemiolgia (Basel, Switzerland) Pub Date : 2024-08-30 DOI: 10.3390/epidemiologia5030039
Laura Merson, Sara Duque, Esteban Garcia-Gallo, Trokon Omarley Yeabah, Jamie Rylance, Janet Diaz, Antoine Flahault, Isaric Clinical Characterisation Group
{"title":"Optimising Clinical Epidemiology in Disease Outbreaks: Analysis of ISARIC-WHO COVID-19 Case Report Form Utilisation.","authors":"Laura Merson, Sara Duque, Esteban Garcia-Gallo, Trokon Omarley Yeabah, Jamie Rylance, Janet Diaz, Antoine Flahault, Isaric Clinical Characterisation Group","doi":"10.3390/epidemiologia5030039","DOIUrl":"10.3390/epidemiologia5030039","url":null,"abstract":"<p><p>Standardised forms for capturing clinical data promote consistency in data collection and analysis across research sites, enabling faster, higher-quality evidence generation. ISARIC and the World Health Organization have developed case report forms (CRFs) for the clinical characterisation of several infectious disease outbreaks. To improve the design and quality of future forms, we analysed the inclusion and completion rates of the 243 fields on the ISARIC-WHO COVID-19 CRF. Data from 42 diverse collaborations, covering 1886 hospitals and 950,064 patients, were analysed. A mean of 129.6 fields (53%) were included in the adapted CRFs implemented across the sites. Consistent patterns of field inclusion and completion aligned with globally recognised research priorities in outbreaks of novel infectious diseases. Outcome status was the most highly included (95.2%) and completed (89.8%) field, followed by admission demographics (79.1% and 91.6%), comorbidities (77.9% and 79.0%), signs and symptoms (68.9% and 78.4%), and vitals (70.3% and 69.1%). Mean field completion was higher in severe patients (70.2%) than in all patients (61.6%). The results reveal how clinical characterisation CRFs can be streamlined to reduce data collection time, including the modularisation of CRFs, to offer a choice of data volume collection and the separation of critical care interventions. This data-driven approach to designing CRFs enhances the efficiency of data collection to inform patient care and public health response.</p>","PeriodicalId":72944,"journal":{"name":"Epidemiolgia (Basel, Switzerland)","volume":"5 3","pages":"557-580"},"PeriodicalIF":0.0,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Caregiver Perception of the Oral-Health-Related Quality of Life of Children with Special Needs: An Exploratory Study. 照顾者对与口腔健康相关的特殊需求儿童生活质量的看法:一项探索性研究
Epidemiolgia (Basel, Switzerland) Pub Date : 2024-08-28 DOI: 10.3390/epidemiologia5030038
Lidia Gavic, Megi Brekalo, Antonija Tadin
{"title":"Caregiver Perception of the Oral-Health-Related Quality of Life of Children with Special Needs: An Exploratory Study.","authors":"Lidia Gavic, Megi Brekalo, Antonija Tadin","doi":"10.3390/epidemiologia5030038","DOIUrl":"10.3390/epidemiologia5030038","url":null,"abstract":"<p><strong>Background: </strong>Compared to the general population, individuals with special needs tend to have worse oral health, potentially diminishing their quality of life. This study aimed to evaluate the perception of parents and caregivers regarding the effect of oral health on the quality of life of individuals with special needs who received dental treatment under general anaesthesia, as well as the impact on their and their families' quality of life.</p><p><strong>Materials and methods: </strong>This cross-sectional study involved participants with special needs who had undergone a dental treatment under general anaesthesia. Before the intervention, an oral examination was conducted to count the number of teeth affected by caries. Parents or caregivers filled out a specially designed questionnaire that included sociodemographic information, details about the children's oral hygiene and dietary habits, and questionnaires on the impact of their child's oral health on their quality of life (P-CPQ) and the influence of the oral health of children with psychophysical difficulties on the family (FIS). The data collected were analysed both descriptively and using the chi-square test, Fisher's exact test, Kruskal-Wallis test, and Spearman's correlation analysis. The level of significance was set at <i>p</i> ≤ 0.05.</p><p><strong>Results: </strong>This study involved 42 children (24 females and 18 males) with an average age of 21.14 ± 8.34 years. The average number of carious teeth per participant was 9.74 ± 5.63. About 66% of respondents reported that their children performed oral hygiene with their help, while 9.5% of them did not do so at all. Individuals with a higher number of caries had statistically significantly higher scores on the emotional well-being (<i>p</i> = 0.004) and social well-being (<i>p</i> = 0.033) subscales of P-CPQ, as well as on the parental emotions subscale of FIS (<i>p</i> = 0.020). Also, there was a difference in the number of carious teeth in participants due to unhealthy habits (drinking sweetened beverages, <i>p</i> = 0.030) and due to comforting with food (<i>p</i> = 0.004).</p><p><strong>Conclusion: </strong>The increase in the number of carious teeth in individuals with special needs has been associated with the quality of life of their families. To address this, it is crucial to promote the prevention of oral health issues by educating individuals with special needs and their caregivers on proper oral hygiene techniques and diets tailored to their specific requirements.</p>","PeriodicalId":72944,"journal":{"name":"Epidemiolgia (Basel, Switzerland)","volume":"5 3","pages":"547-556"},"PeriodicalIF":0.0,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors and Preventive Measures for Lung Cancer in the European Union. 欧盟肺癌的风险因素和预防措施。
Epidemiolgia (Basel, Switzerland) Pub Date : 2024-08-27 DOI: 10.3390/epidemiologia5030037
Katharina Kehrle, Michael Hetjens, Svetlana Hetjens
{"title":"Risk Factors and Preventive Measures for Lung Cancer in the European Union.","authors":"Katharina Kehrle, Michael Hetjens, Svetlana Hetjens","doi":"10.3390/epidemiologia5030037","DOIUrl":"10.3390/epidemiologia5030037","url":null,"abstract":"<p><strong>Background: </strong>Lung cancer is worldwide one of the most common types of cancer with still very high mortality rates. The aim of this study was to identify and demonstrate correlations between lung cancer mortality rates and potential influencing factors in EU countries.</p><p><strong>Methods: </strong>This retrospective study investigated the connections between the mortality rates in the EU countries (n = 28) and potential influencing factors. The significant factors from the correlation analysis were identified using a stepwise multiple regression analysis.</p><p><strong>Results: </strong>The most important factors for both genders are the incidence of lung cancer, the price of tobacco, and the number of doctors per 100,000 inhabitants.</p><p><strong>Conclusion: </strong>Lung cancer is a significant global health challenge. The study identified potential strategies for reducing the mortality rate from lung cancer. These strategies include an increase in the number of physicians, enhanced accessibility to cutting-edge antineoplastic medications, and state-funded coverage of the associated costs. It would be beneficial for politicians to consider implementing LDCT screening for the early detection of the disease. The implementation of uniform healthcare system optimization across the EU, combined with improvements in socio-economic conditions, has the potential to mitigate the risk of developing lung cancer.</p>","PeriodicalId":72944,"journal":{"name":"Epidemiolgia (Basel, Switzerland)","volume":"5 3","pages":"539-546"},"PeriodicalIF":0.0,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cyberchondria, Health Literacy, and Perception of Risk in Croatian Patients with Risk of Sexually Transmitted Infections and HIV-A Cross-Sectional Study. 克罗地亚性传播感染和艾滋病毒风险患者的网络ondria、健康素养和风险意识--一项横断面研究。
Epidemiolgia (Basel, Switzerland) Pub Date : 2024-08-22 DOI: 10.3390/epidemiologia5030036
Tanja Staraj Bajcic, Iva Sorta-Bilajac Turina, Marko Lucijanic, Tamara Sinozic, Mirela Vuckovic, Ksenija Bazdaric
{"title":"Cyberchondria, Health Literacy, and Perception of Risk in Croatian Patients with Risk of Sexually Transmitted Infections and HIV-A Cross-Sectional Study.","authors":"Tanja Staraj Bajcic, Iva Sorta-Bilajac Turina, Marko Lucijanic, Tamara Sinozic, Mirela Vuckovic, Ksenija Bazdaric","doi":"10.3390/epidemiologia5030036","DOIUrl":"10.3390/epidemiologia5030036","url":null,"abstract":"<p><p><b>Background:</b> The perception of the risk of sexually transmitted infections (STIs) is a well-researched phenomenon, but not in relation to cyberchondria and health literacy. Therefore, our aim was to examine the association between the assessment of the risk of sexually transmitted diseases and HIV, cyberchondria, and health literacy. <b>Materials and methods</b>: This study was conducted in 2020-2021 in Croatia. The experimental group consisted of patients from the Centre for Voluntary Counselling and Testing for HIV (N = 134). The control group consisted of other patients recruited from daily epidemiological practices (N = 171). The instruments that were used were questionnaires that measure the perception of risk of sexually transmitted infections and HIV, health literacy, and cyberchondria. <b>Results</b>: Out of 305 respondents, 134 (43.9%) were in the STI counselling group, and 171 (56.1%) were in the control group. Generally, the participants in the former perceived the risk of sexually transmitted infections and HIV to be higher (but still low) than those in the latter. There was no difference in health literacy between the STI and control group; the health literacy score was average in both groups. There were differences in almost all the cyberchondria factors, except for Mistrust. Health literacy, belonging to the STI counselling group, and risk behaviours were positively associated with CH in the logistic regression analysis. <b>Conclusions</b>: People with a risk for STIs tend to minimize this risk, have higher cyberchondria levels, and have average health literacy. Cyberchondria is positively associated with health literacy, and more education about excessive health-related internet research is needed.</p>","PeriodicalId":72944,"journal":{"name":"Epidemiolgia (Basel, Switzerland)","volume":"5 3","pages":"525-538"},"PeriodicalIF":0.0,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Video Game Addiction in Young People (8-18 Years Old) after the COVID-19 Pandemic: The Grey Area of Addiction and the Phenomenon of "Gaming Non-Pathological Abuse (GNPA)". COVID-19 大流行后青少年(8-18 岁)的电子游戏成瘾问题:成瘾的灰色地带和 "游戏非病理性滥用(GNPA)"现象。
Epidemiolgia (Basel, Switzerland) Pub Date : 2024-08-12 DOI: 10.3390/epidemiologia5030035
Domenico Piccininno, Giulio Perrotta
{"title":"Video Game Addiction in Young People (8-18 Years Old) after the COVID-19 Pandemic: The Grey Area of Addiction and the Phenomenon of \"Gaming Non-Pathological Abuse (GNPA)\".","authors":"Domenico Piccininno, Giulio Perrotta","doi":"10.3390/epidemiologia5030035","DOIUrl":"10.3390/epidemiologia5030035","url":null,"abstract":"<p><strong>Introduction: </strong>In the literature, video game addiction in youths is correlated with dysfunctional symptoms of anxiety, emotional disorders, and mood disorders, and the pandemic period of 2020-2022 has favored the aggravation of this behavioral addiction. Therefore, we identified the need to analyze this phenomenon with an emphasis on the risks and correlates related to deviance and maladjustment from a prospective perspective, seeking to understand the impact of the individual variables examined.</p><p><strong>Aim: </strong>To demonstrate whether the condition of \"gaming non-pathological abuse\" (GNPA) promotes psychopathological features of clinical interest, in the absence of a diagnosis of \"gaming disorder\" (GD).</p><p><strong>Materials and methods: </strong>A search performed on PubMed and administration of an ad hoc sociological questionnaire were used to investigate individual variables of criminological interest in a representative population sample (531 males/females, 8-18 years old, M: 14.4, SD: 2.5).</p><p><strong>Results: </strong>Statistical analysis showed that after the pandemic period, digital video game addiction was reinforced, feeding psychopathological traits consistent with anxiety, emotional disorders, and mood disorders. Variables correlated with impulsive, aggressive, and violent behavior related to age, gender, socio-environmental and economic background, and the severity of digital video game addiction.</p><p><strong>Conclusions: </strong>In the youth population (8-18 years), \"gaming non-pathological abuse\" (GNPA) is related to aggressive, impulsive and violent behaviors that foster phenomena of social maladjustment and deviance, especially in individuals living in disadvantaged or otherwise complex socio-economic and family contexts. Looking forward, the study of structural and functional personality profiles is essential in order to anticipate and reduce the future risk of psychopathological and criminal behavior.</p>","PeriodicalId":72944,"journal":{"name":"Epidemiolgia (Basel, Switzerland)","volume":"5 3","pages":"511-524"},"PeriodicalIF":0.0,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11348197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142074549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occurrence of Central Nervous System Complications of Respiratory Syncytial Virus Infections: A Systematic Review with Meta-Analysis. 呼吸道合胞病毒感染引起的中枢神经系统并发症:系统综述与元分析》。
Epidemiolgia (Basel, Switzerland) Pub Date : 2024-07-19 DOI: 10.3390/epidemiologia5030031
Matteo Riccò, Antonio Cascio, Silvia Corrado, Marco Bottazzoli, Federico Marchesi, Renata Gili, Pasquale Gianluca Giuri, Davide Gori, Paolo Manzoni
{"title":"Occurrence of Central Nervous System Complications of Respiratory Syncytial Virus Infections: A Systematic Review with Meta-Analysis.","authors":"Matteo Riccò, Antonio Cascio, Silvia Corrado, Marco Bottazzoli, Federico Marchesi, Renata Gili, Pasquale Gianluca Giuri, Davide Gori, Paolo Manzoni","doi":"10.3390/epidemiologia5030031","DOIUrl":"10.3390/epidemiologia5030031","url":null,"abstract":"<p><p>An increasing base of evidence suggests that respiratory syncytial virus (RSV) infections may be associated with neurological complications. In accord with the PRISMA statement, we performed a systematic review and meta-analysis on the occurrence of encephalitis and encephalopathy associated with documented RSV infections. PubMed, Embase, and Scopus databases were searched for eligible observational studies published up to 10 April 2024. Raw data included the occurrence of RSV infections among cases of encephalitis and/or encephalopathy and cases of encephalitis and/or encephalopathy among series of RSV infections. Data were pooled in a random effects model. Case reports were also collected, and their data pooled as a cumulative series. Heterogeneity was assessed using the I<sup>2</sup> measure, while reporting bias was assessed by means of funnel plots and regression analysis. A total of 15 studies for a total of 7719 RSV infections and 1631 cases of encephalitis were analyzed. Moreover, 27 case reports and case series were retrieved, for a total of 84 individual cases of encephalitis/encephalopathy occurring during a documented RSV infection. A pooled prevalence of 2.20 cases of encephalitis/encephalopathy per 100 RSV cases (I<sup>2</sup> = 99%) was calculated, while a prevalence of RSV infections among cases of encephalitis/encephalopathy was estimated to 3.53 per 100 cases for studies on respiratory specimens (I<sup>2</sup> = 48%) and 0.37 per cases on central nervous system (CNS) specimens (I<sup>2</sup> = 0%). Detection of RSV within the CNS was relatively rare (17.86% of pooled case reports), being associated with male gender (adjusted odds ratio [aOR] 5.021, 95% confidence interval [95%CI] 1.104 to 22.831) and recovery with long-term sequelae (aOR 5.699, 95%CI 1.152; 28.183). Case fatality ratio was estimated to be 0.43 per 100 cases on observational studies and 10.71% in case reports, a difference likely due to publication bias. In summary, RSV represented a not frequent but notable cause of encephalitis/encephalopathy in adults and children. The paucity of available studies not only recommends a cautious appraisal of our results but stresses the clinical significance of future studies on incident cases of encephalitis and/or encephalopathy.</p>","PeriodicalId":72944,"journal":{"name":"Epidemiolgia (Basel, Switzerland)","volume":"5 3","pages":"421-455"},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11270441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141763095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation between Breastfeeding, Maternal Body Mass Index, and Childhood Obesity. 母乳喂养、母亲体重指数与儿童肥胖之间的相关性。
Epidemiolgia (Basel, Switzerland) Pub Date : 2024-07-19 DOI: 10.3390/epidemiologia5030030
Ermioni Palaska, Evangelia Antoniou, Maria Tzitiridou-Chatzopoulou, Panagiotis Eskitzis, Eirini Orovou
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