发布求助
文献互助 智能选刊 最新文献

Advanced drug delivery reviews最新文献

筛选
英文 中文
Light sheet fluorescence microscopy for monitoring drug delivery: Unlocking the developmental phases of embryos 用于监测药物输送的光片荧光显微镜：揭开胚胎发育阶段的神秘面纱
IF 15.2 1区 医学
Advanced drug delivery reviews Pub Date : 2025-01-20 DOI: 10.1016/j.addr.2025.115520
Gagan Raju , Aymeric Le Gratiet , Giuseppe Sancataldo , Guan-Yu Zhuo , Yury Kistenev , Subir Das , Ajeetkumar Patil , Nirmal Mazumder
{"title":"Light sheet fluorescence microscopy for monitoring drug delivery: Unlocking the developmental phases of embryos","authors":"Gagan Raju ,&nbsp;Aymeric Le Gratiet ,&nbsp;Giuseppe Sancataldo ,&nbsp;Guan-Yu Zhuo ,&nbsp;Yury Kistenev ,&nbsp;Subir Das ,&nbsp;Ajeetkumar Patil ,&nbsp;Nirmal Mazumder","doi":"10.1016/j.addr.2025.115520","DOIUrl":"10.1016/j.addr.2025.115520","url":null,"abstract":"<div><div>Light sheet fluorescence microscopy (LSFM) has emerged as a transformative imaging technique in the study of drug delivery and embryonic development, offering high-resolution, real-time visualization with minimal phototoxicity. This review examines the application of LSFM in tracking drug pharmacokinetics, tissue-specific targeting, and drug efficacy during critical phases of embryonic development. Recent advancements in fluorescent labeling and machine learning integration have enabled more precise monitoring of drug release, distribution, and interaction with developing tissues. The ability of LSFM to capture long-term dynamics at single-cell resolution has revolutionized drug discovery, especially in nanomedicine and targeted therapies. By integrating LSFM with multimodal imaging and AI-driven data analysis, researchers are now better equipped to explore complex biological processes and optimize drug delivery in a highly controlled, minimally invasive manner. Finally, the review highlights the pivotal role of LSFM in advancing drug delivery research, addressing existing challenges, and unlocking new frontiers in clinical applications.</div></div>","PeriodicalId":7254,"journal":{"name":"Advanced drug delivery reviews","volume":"218 ","pages":"Article 115520"},"PeriodicalIF":15.2,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142990853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug delivery systems for treating neurodevelopmental disorders 治疗神经发育障碍的给药系统。
IF 15.2 1区 医学
Advanced drug delivery reviews Pub Date : 2025-01-01 DOI: 10.1016/j.addr.2024.115473
Boaz Barak, Paolo Decuzzi
{"title":"Drug delivery systems for treating neurodevelopmental disorders","authors":"Boaz Barak,&nbsp;Paolo Decuzzi","doi":"10.1016/j.addr.2024.115473","DOIUrl":"10.1016/j.addr.2024.115473","url":null,"abstract":"","PeriodicalId":7254,"journal":{"name":"Advanced drug delivery reviews","volume":"216 ","pages":"Article 115473"},"PeriodicalIF":15.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Super-resolution imaging of sub-cellular dynamics of drug molecules 药物分子亚细胞动态超分辨率成像。
IF 15.2 1区 医学
Advanced drug delivery reviews Pub Date : 2025-01-01 DOI: 10.1016/j.addr.2024.115455
Qixin Chen, Jiajie Diao
{"title":"Editorial: Super-resolution imaging of sub-cellular dynamics of drug molecules","authors":"Qixin Chen,&nbsp;Jiajie Diao","doi":"10.1016/j.addr.2024.115455","DOIUrl":"10.1016/j.addr.2024.115455","url":null,"abstract":"","PeriodicalId":7254,"journal":{"name":"Advanced drug delivery reviews","volume":"216 ","pages":"Article 115455"},"PeriodicalIF":15.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RNA delivery technologies: From concept toward the clinic 前言：RNA 输送技术：从概念走向临床
IF 15.2 1区 医学
Advanced drug delivery reviews Pub Date : 2025-01-01 DOI: 10.1016/j.addr.2024.115471
María J. Blanco-Prieto, Elisa Garbayo
{"title":"RNA delivery technologies: From concept toward the clinic","authors":"María J. Blanco-Prieto,&nbsp;Elisa Garbayo","doi":"10.1016/j.addr.2024.115471","DOIUrl":"10.1016/j.addr.2024.115471","url":null,"abstract":"","PeriodicalId":7254,"journal":{"name":"Advanced drug delivery reviews","volume":"216 ","pages":"Article 115471"},"PeriodicalIF":15.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142541487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Subcellular organelle-targeting of nanomaterials for enhancing therapeutic effectiveness 社论：纳米材料的亚细胞器靶向技术提高治疗效果
IF 15.2 1区 医学
Advanced drug delivery reviews Pub Date : 2025-01-01 DOI: 10.1016/j.addr.2024.115460
Yu Seok Youn, Koen Raemdonck
{"title":"Editorial: Subcellular organelle-targeting of nanomaterials for enhancing therapeutic effectiveness","authors":"Yu Seok Youn,&nbsp;Koen Raemdonck","doi":"10.1016/j.addr.2024.115460","DOIUrl":"10.1016/j.addr.2024.115460","url":null,"abstract":"","PeriodicalId":7254,"journal":{"name":"Advanced drug delivery reviews","volume":"216 ","pages":"Article 115460"},"PeriodicalIF":15.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142449790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Editorial: Advanced strategies to bridge the gap between inflammation and tissue regeneration” [Adv. Drug Deliv. Rev. 209 (2024) 115328] 社论：弥合炎症和组织再生之间差距的先进战略"[Adv. Drug Deliv. Rev. 209 (2024) 115328]
IF 15.2 1区 医学
Advanced drug delivery reviews Pub Date : 2025-01-01 DOI: 10.1016/j.addr.2024.115457
Márcia T. Rodrigues, Manuela E. Gomes
{"title":"Corrigendum to “Editorial: Advanced strategies to bridge the gap between inflammation and tissue regeneration” [Adv. Drug Deliv. Rev. 209 (2024) 115328]","authors":"Márcia T. Rodrigues,&nbsp;Manuela E. Gomes","doi":"10.1016/j.addr.2024.115457","DOIUrl":"10.1016/j.addr.2024.115457","url":null,"abstract":"","PeriodicalId":7254,"journal":{"name":"Advanced drug delivery reviews","volume":"216 ","pages":"Article 115457"},"PeriodicalIF":15.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142486848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug delivery using gold nanoparticles 利用金纳米颗粒给药
IF 15.2 1区 医学
Advanced drug delivery reviews Pub Date : 2024-11-29 DOI: 10.1016/j.addr.2024.115481
Lev Dykman , Boris Khlebtsov , Nikolai Khlebtsov
{"title":"Drug delivery using gold nanoparticles","authors":"Lev Dykman ,&nbsp;Boris Khlebtsov ,&nbsp;Nikolai Khlebtsov","doi":"10.1016/j.addr.2024.115481","DOIUrl":"10.1016/j.addr.2024.115481","url":null,"abstract":"<div><div>Modern nanotechnologies provide various possibilities for efficiently delivering drugs to biological targets. This review focuses on using functionalized gold nanoparticles (GNPs) as a drug delivery platform. Owing to their exceptional size and surface characteristics, GNPs are a perfect drug delivery vehicle for targeted and selective distribution. Several <em>in vitro</em> and <em>in vivo</em> tests have shown how simple it is to tailor these particles to administer chemical medications straight to tumors. The GNP surface can also be coated with ligands to modify drug release or improve selectivity. Moreover, the pharmacological activity can be enhanced by using the photothermal characteristics of the particles.</div></div>","PeriodicalId":7254,"journal":{"name":"Advanced drug delivery reviews","volume":"216 ","pages":"Article 115481"},"PeriodicalIF":15.2,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142742414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biopharmaceutical drug delivery and phototherapy using protein crystals 利用蛋白质晶体进行生物制药给药和光疗
IF 15.2 1区 医学
Advanced drug delivery reviews Pub Date : 2024-11-28 DOI: 10.1016/j.addr.2024.115480
Renbin Zhou , Jinghan Qu , Xuejiao Liu , Fangrui Lin , Tymish Y. Ohulchanskyy , Nuernisha Alifu , Junle Qu , Da-Chuan Yin
{"title":"Biopharmaceutical drug delivery and phototherapy using protein crystals","authors":"Renbin Zhou ,&nbsp;Jinghan Qu ,&nbsp;Xuejiao Liu ,&nbsp;Fangrui Lin ,&nbsp;Tymish Y. Ohulchanskyy ,&nbsp;Nuernisha Alifu ,&nbsp;Junle Qu ,&nbsp;Da-Chuan Yin","doi":"10.1016/j.addr.2024.115480","DOIUrl":"10.1016/j.addr.2024.115480","url":null,"abstract":"<div><div>Biopharmaceutical drugs, including proteins, peptides, and antibodies, are renowned for their high specificity and efficacy, fundamentally transforming disease treatment paradigms. However, their structural complexity presents challenges for their formulation and delivery. Protein crystals, characterized by high purity, high stability and a porous structure for biopharmaceutical drug encapsulation, providing a potential avenue for formulating and delivering biopharmaceutical drugs. There is increasing interest in engineering protein crystals to delivery biopharmaceutical drugs for biomedical applications. This review summarizes the recent advances in biopharmaceutical drug delivery and phototherapy using protein crystals. First, we evaluate the advantages of using protein crystals for biopharmaceutical drugs delivery. Next, we outline the strategies for <em>in vitro</em> and <em>in vivo</em> crystallization to prepare protein crystals. Importantly, the review highlights the advanced applications of protein crystals in biopharmaceutical drug delivery, tumor phototherapy, and other optical fields. Finally, it provides insights into future perspectives of biopharmaceutical drug delivery using protein crystals. This comprehensive review aims to provide effective insights into design of protein crystals to simplify biopharmaceutical drug delivery and improve disease treatment.</div></div>","PeriodicalId":7254,"journal":{"name":"Advanced drug delivery reviews","volume":"216 ","pages":"Article 115480"},"PeriodicalIF":15.2,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142735727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D printing of drug delivery systems enhanced with micro/nano-technology 利用微/纳米技术增强给药系统的 3D 打印技术
IF 15.2 1区 医学
Advanced drug delivery reviews Pub Date : 2024-11-26 DOI: 10.1016/j.addr.2024.115479
Hui Zhu , Huijuan Kuang , Xinxin Huang , Xiao Li , Ruosen Zhao , Guojin Shang , Ziyu Wang , Yucheng Liao , Jiankang He , Dichen Li
{"title":"3D printing of drug delivery systems enhanced with micro/nano-technology","authors":"Hui Zhu ,&nbsp;Huijuan Kuang ,&nbsp;Xinxin Huang ,&nbsp;Xiao Li ,&nbsp;Ruosen Zhao ,&nbsp;Guojin Shang ,&nbsp;Ziyu Wang ,&nbsp;Yucheng Liao ,&nbsp;Jiankang He ,&nbsp;Dichen Li","doi":"10.1016/j.addr.2024.115479","DOIUrl":"10.1016/j.addr.2024.115479","url":null,"abstract":"<div><div>Drug delivery systems (DDSs) are increasingly important in ensuring drug safety and enhancing therapeutic efficacy. Micro/nano-technology has been utilized to develop DDSs for achieving high stability, bioavailability, and drug efficiency, as well as targeted delivery; meanwhile, 3D printing technology has made it possible to tailor DDSs with diverse components and intricate structures. This review presents the latest research progress integrating 3D printing technology and micro/nano-technology for developing novel DDSs. The technological fundamentals of 3D printing technology supporting the development of DDSs are presented, mainly from the perspective of different 3D printing mechanisms. Distinct types of DDSs leveraging 3D printing and micro/nano-technology are analyzed deeply, featuring micro/nanoscale materials and structures to enrich functionalities and improve effectiveness. Finally, we will discuss the future directions of 3D-printed DDSs integrated with micro/nano-technology, focusing on technological innovation and clinical application. This review will support interdisciplinary research efforts to advance drug delivery technology.</div></div>","PeriodicalId":7254,"journal":{"name":"Advanced drug delivery reviews","volume":"216 ","pages":"Article 115479"},"PeriodicalIF":15.2,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142712594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrated pharmacokinetic-pharmacodynamic and agent-based modelling in drug development: Current status and future perspectives 药物开发中的药代动力学-药效学和基于代理的综合建模：现状与未来展望
IF 15.2 1区 医学
Advanced drug delivery reviews Pub Date : 2024-11-23 DOI: 10.1016/j.addr.2024.115474
James W.T. Yates
{"title":"Integrated pharmacokinetic-pharmacodynamic and agent-based modelling in drug development: Current status and future perspectives","authors":"James W.T. Yates","doi":"10.1016/j.addr.2024.115474","DOIUrl":"10.1016/j.addr.2024.115474","url":null,"abstract":"<div><div>In the past two decades, quantitative mathematical modelling approaches have emerged as a paradigm to improve new drug research productivity, especially the application of pharmacokinetic-pharmacodynamic and quantitative systems pharmacology modelling. These approaches have largely made use of deterministic, differential equation-based models, however there is a growing use of agent-based models. In this review, the current applications and practices of agent-based model development are reviewed via relevant case studies from the literature. Gaps in the implementation of these models are identified and a future perspective on the priorities for further agent-based model development is given.</div></div>","PeriodicalId":7254,"journal":{"name":"Advanced drug delivery reviews","volume":"216 ","pages":"Article 115474"},"PeriodicalIF":15.2,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142694205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信