Brain & spine最新文献

{"title":"Intraparenchymal schwannoma in an adult presenting as a periventricular lesion of the parieto-occipital lobes: Diagnostic and surgical challenges","authors":"Christin Berjaoui ,&nbsp;Ali Akil ,&nbsp;Hussein Akil ,&nbsp;Paul Hage ,&nbsp;Joseph Mantoura","doi":"10.1016/j.bas.2025.105601","DOIUrl":"10.1016/j.bas.2025.105601","url":null,"abstract":"<div><h3>Introduction</h3><div>Intraparenchymal schwannomas (IS) are exceedingly rare, constituting less than 1 % of all intracranial schwannomas. To date, approximately 150 cases have been reported in the literature, with only 10 involving the parieto-occipital region. Unlike vestibular schwannomas, IS lacks an apparent association with cranial nerves and often mimics high-grade gliomas or metastatic tumors, leading to diagnostic uncertainty.</div></div><div><h3>Research question</h3><div>How does the extreme rarity and atypical parieto-occipital location of intraparenchymal schwannomas contribute to diagnostic challenges and potential misdiagnosis?</div></div><div><h3>Materials and methods</h3><div>A comprehensive literature search was conducted using PubMed, MEDLINE, and Google Scholar with the keyword “Intraparenchymal Schwannoma”. A total of 150 previously reported cases were used for the literature.</div></div><div><h3>Results</h3><div>We report the case of a 56-year-old female presenting with progressive dysarthria, vertigo, ataxia, and right-sided hemiparesis. MRI revealed a large left parieto-occipital periventricular lesion with mixed solid and cystic components and significant perilesional edema. Given the progressive neurological deterioration, gross total resection of the lesion was performed. Intraoperatively, the tumor exhibited a firm, well-circumscribed morphology. Histopathological examination confirmed the diagnosis of schwannoma, a finding highly unusual in this location.</div></div><div><h3>Conclusion</h3><div>This case highlights the diagnostic challenges of IS and the importance of surgical resection in achieving favorable neurological outcomes. Given their radiological overlap with aggressive neoplasms, advanced neuroimaging, and careful surgical management are essential for optimizing outcomes. Increased awareness of this rare pathology can aid in early recognition, prevent misdiagnosis, and guide effective neurosurgical strategies.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 105601"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145158039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Best Abstract: Innovative Reviving Matrix for Reconstruction of Traumatic Injuries to the Peripheral Nerves and Spinal Cord","authors":"Shimon Rochkind (Prof) ,&nbsp;Dr. Mara Almog ,&nbsp;Zvi Nevo (Prof)","doi":"10.1016/j.bas.2025.104913","DOIUrl":"10.1016/j.bas.2025.104913","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104913"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overcoming the Inoperability Barrier in Frail Patients affected by Glioblastoma: A Multivariate and Machine Learning analysis","authors":"Dr. Luana Conte ,&nbsp;Donato Cascio (Prof) ,&nbsp;Dr. Tamara Ius ,&nbsp;Giovanni Sabatino (Prof) ,&nbsp;Dr. Francesco Bruno ,&nbsp;Dr. Anna Luisa Di Stefano ,&nbsp;Dr. Orazio Santanocito ,&nbsp;Dr. Gerardo Caruso ,&nbsp;Dr. Giovanni Raffa ,&nbsp;Dr. Cristofer Gonzalo Garcia Moreira ,&nbsp;Dr. Federico Villanacci ,&nbsp;Dr. Teresa Somma ,&nbsp;Giuseppe Raso (Prof) ,&nbsp;Giorgio De Nunzio (Prof) ,&nbsp;Dr. Alessandro Olivi ,&nbsp;Giuseppe Lombardi (Prof) ,&nbsp;Dr. Roberta Rudà ,&nbsp;Dr. Filippo Flavio Angileri ,&nbsp;Dr. Paola Gaviani ,&nbsp;Dr. Antonio Silvani ,&nbsp;Maria Caffo (Prof)","doi":"10.1016/j.bas.2025.104939","DOIUrl":"10.1016/j.bas.2025.104939","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104939"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Endonasal Approach for Rare Skull Base Pathologies: Insights from a Neurosurgical Perspective","authors":"Dr. Atakan Emengen ,&nbsp;Dr. Aykut Gokbel ,&nbsp;Dr. Eren Yilmaz ,&nbsp;Dr. Ayse Uzuner ,&nbsp;Dr. Melih Caklili ,&nbsp;Dr. Burak Cabuk ,&nbsp;Ihsan Anik (Prof) ,&nbsp;Özlem Yapıcıer (Prof) ,&nbsp;Savas Ceylan (Prof)","doi":"10.1016/j.bas.2025.104953","DOIUrl":"10.1016/j.bas.2025.104953","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104953"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypofractionated Gamma Knife ICON radiosurgery for perioptic meningiomas","authors":"Dr. Alberto Franzin ,&nbsp;Dr. Karol Migliorati ,&nbsp;Dr. Chiara Zani ,&nbsp;PhD Clarissa Ferrari ,&nbsp;Dr. Lodoviga Giudice ,&nbsp;Dr. Nicola Redolfi ,&nbsp;Dr. Giorgio Spatola ,&nbsp;Dr. Rosaria Maio ,&nbsp;Dr. Alessandra Huscher ,&nbsp;Dr. Mario Bignardi","doi":"10.1016/j.bas.2025.104968","DOIUrl":"10.1016/j.bas.2025.104968","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104968"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implication of SLIT/ROBO Signaling Pathway In Glioblastoma Progression And Prognosis","authors":"Dr. Anastasios Politis ,&nbsp;Dr. Lampis Stavrinou ,&nbsp;Dr. Aristotelis Kalyvas ,&nbsp;Dr. Evgenia Lani ,&nbsp;Dr. Panagiotis Zemperligkos ,&nbsp;Dr. Evangelos Papadopoulos ,&nbsp;Dr. Stamatis Banos ,&nbsp;Dr. Georgios Savvanis ,&nbsp;Dr. Ioannis Ydreos ,&nbsp;Dr. Maria Gavra ,&nbsp;Efstathios Boviatsis (Prof) ,&nbsp;Christina Piperi (Prof)","doi":"10.1016/j.bas.2025.104928","DOIUrl":"10.1016/j.bas.2025.104928","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104928"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of cerebrovascular reactivity and STA-MCA bypass flow","authors":"Dr. Martina Sebök ,&nbsp;Dr. Vittorio Stumpo ,&nbsp;Dr. Jacopo Bellomo ,&nbsp;Dr. Giuseppe Esposito ,&nbsp;Luca Regli (Prof.) ,&nbsp;Dr. Jorn Fierstra","doi":"10.1016/j.bas.2025.104921","DOIUrl":"10.1016/j.bas.2025.104921","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104921"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric intracranial infections requiring neurosurgery: A German multicenter analysis of ten-year trends pre- and post-COVID-19","authors":"Dr. Daniel Dubinski ,&nbsp;Dr. Sae-Yeon Won ,&nbsp;Dr. Artem Rafaelian ,&nbsp;Ulrich Sure (Prof) ,&nbsp;Phillipp Dammann (Prof) ,&nbsp;Dr. Laurèl Rauschenbach ,&nbsp;Christian Senft (Prof) ,&nbsp;Dr. Nazife Dinc ,&nbsp;Dr. Nazeer Aboud ,&nbsp;Florian Ringel (Prof) ,&nbsp;Dr. Malte Ottenhausen ,&nbsp;Dr. Daniel Scurtu ,&nbsp;Wolfgang Deinsberger (Prof) ,&nbsp;Dr. Stefanie Kästner ,&nbsp;Dr. Jo Chen ,&nbsp;Veit Rohde (Prof) ,&nbsp;Friederike Knerlich-Lukoschus (Prof) ,&nbsp;Dr. Hans Bock ,&nbsp;Dr. Silvia Hernandez ,&nbsp;Dorothee Mielke (Prof) ,&nbsp;Florian Gessler (Prof)","doi":"10.1016/j.bas.2025.104986","DOIUrl":"10.1016/j.bas.2025.104986","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104986"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Evolving Neurosurgical Landscape of Gender Representation in Germany: Three Decades of Change","authors":"Dr. Felix Corr ,&nbsp;Dr. Anna M. Zeitlberger ,&nbsp;PD Dr Ph.D. Isabel C. Hostettler ,&nbsp;Dr. Marian C. Neidert (Prof.) ,&nbsp;Dr. Oliver Bozinov (Prof.) ,&nbsp;Dr. Stefan Motov","doi":"10.1016/j.bas.2025.104995","DOIUrl":"10.1016/j.bas.2025.104995","url":null,"abstract":"","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104995"},"PeriodicalIF":2.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lumbar disc space height in relation to neural foraminal dimensions and patient characteristics: A morphometric analysis from L1-S1 using computed tomography","authors":"David Shin ,&nbsp;Ethan Vyhmeister ,&nbsp;Daniel Im ,&nbsp;Andrew Fay ,&nbsp;Owen Faehner ,&nbsp;Andrew Cabrera ,&nbsp;Alexander Bouterse ,&nbsp;Lauren Seo ,&nbsp;Derran Bedward ,&nbsp;Mei Carter ,&nbsp;Davis Carter ,&nbsp;Jacob Razzouk ,&nbsp;Omar Ramos ,&nbsp;Nathaniel Wycliffe ,&nbsp;Wayne Cheng ,&nbsp;Olumide Danisa","doi":"10.1016/j.bas.2024.104162","DOIUrl":"10.1016/j.bas.2024.104162","url":null,"abstract":"<div><h3>Introduction</h3><div>The normative relationship between lumbar intervertebral disc space height (DSH) and neuroforaminal dimensions (NFD) has yet to be defined.</div></div><div><h3>Research question</h3><div>The purpose of this study was to investigate the relationship between lumbar DSH and NFD using computed tomography (CT), accounting for influences of patient demographic and anthropometric characteristics.</div></div><div><h3>Materials and methods</h3><div>We analyzed CT imaging of 350 female and 350 male patients. Anterior, middle, and posterior DSH were measured. NFD were defined as sagittal anterior-to-posterior (AP) width, axial AP width, foraminal height, and area. Statistical analyses were performed to assess associations among DSH, NFD, and patient height, weight, body mass index, sex, and ethnicity.</div></div><div><h3>Results</h3><div>Irrespective of disc level, mean anterior, middle, and posterior DSH were 7.98 mm (n = 3500), 8.16 mm (n = 3500), and 4.09 mm (n = 3500). DSH measurements demonstrated increasing, linear trends moving caudally from L1-L2 to L5-S1, while NFD demonstrated a unimodal distribution pattern with largest NFD at L3-L4 and smallest NFD at L1-2 and L5-S1. Male patients demonstrated larger DSH compared to female patients from L1-S1. Asian patients demonstrated taller DSH across all levels L1-S1.</div></div><div><h3>Discussion and conclusion</h3><div>This study describes 38,500 CT-based L1-S1 DSH and NFD in young patients without spinal pathology. DSH follows an increasing trend moving caudally from L1-S1, while NFD demonstrate a unimodal distribution clustered at L3-L4. NFD are not moderately or strongly associated with DSH. DSH is influenced by sex and ethnicity but is not moderately or strongly influenced by patient height, weight, and BMI.</div></div>","PeriodicalId":72443,"journal":{"name":"Brain & spine","volume":"5 ","pages":"Article 104162"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11700277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}