Biomaterial investigations in dentistry最新文献

{"title":"Redefining regeneration: proposal of a radiographic outcome-based framework for evaluating regenerative endodontic procedures in immature necrotic teeth.","authors":"Ruchi Singhal, Akshita Bansal, Shiwani Chawla, Ritu Namdev","doi":"10.2340/biid.v13.46956","DOIUrl":"https://doi.org/10.2340/biid.v13.46956","url":null,"abstract":"<p><strong>Purpose: </strong>To propose a radiographic classification system for evaluating outcomes of regenerative endodontic procedures (REPs) in immature necrotic permanent teeth.</p><p><strong>Methods: </strong>A two-phase retrospective study was conducted. In Phase I, radiographs of 20 cases (2015-2018) were analyzed to identify patterns of apical closure, root lengthening, dentinal wall thickening, intracanal calcification, and periapical healing. Based on these findings, a six-class radiographic classification was proposed:Class 1: Apical closure with increased root length and dentin thickness;Class 2: Apical closure with increased root length only;Class 3: Apical closure with increased dentin thickness only;Class 4: Apical closure without changes in root length or dentin thickness;Class 5: Barrier formation within the canal or coronal to the root end;Class 6: No root dimensional changes with periapical healing of a documented pretreatment periapical radiolucency.In Phase II, the classification was applied to 54 immature single-rooted permanent teeth from 44 patients aged 8-13 years treated with REPs between 2019 and 2023. Baseline and latest available follow-up radiographs were evaluated by two blinded examiners. Reproducibility was assessed using Cohen's kappa, and associations with age and pre-treatment root stage were analyzed using Fisher's exact test.</p><p><strong>Results: </strong>Class 1 was most frequent. Partial intracanal calcification occurred in 35.18% of cases, with no complete canal obliteration. Age (<i>p</i> = 0.215) and pre-treatment root stage (<i>p</i> = 0.872) were not significantly associated with outcome classes. Inter- and intra-examiner agreement were high (κ = 0.82 and 0.86). All cases were accommodated within the six proposed categories, and no additional outcome classes were observed.</p><p><strong>Conclusion: </strong>This proposed six-class radiographic framework demonstrated good internal reproducibility and may provide a structured basis for outcome reporting after REPs. Prospective multicenter validation is required.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"46956"},"PeriodicalIF":0.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13656072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative effect of polishing and coatings on the surface properties of 3D-printed denture-base resin and teeth: an in vitro study.","authors":"Yousif A Al-Dulaijan, Alawiyyah Alsayed, Mashael Alhejji, Saja Alsuwailem, Jehad Almutiri, Soban Q Khan, Abdulrahman A Balhaddad, Shaimaa M Fouda, Mohammed M Gad","doi":"10.2340/biid.v13.46909","DOIUrl":"https://doi.org/10.2340/biid.v13.46909","url":null,"abstract":"<p><strong>Background: </strong>The surface properties of three-dimensional (3D)-printed resins remain an area requiring further improvement. Therefore, this study aimed to evaluate the effects of different polishing and coating protocols on the surface roughness and hardness of 3D-printed denture base resins (DBRs) and denture teeth.</p><p><strong>Methods: </strong>Two 3D printed resins (ASIGA and NextDent) for DBRs and denture teeth were used to fabricate disk-shaped (15 ×2 mm) specimens. Per resin, 96 specimens (48 for denture base and 48 for teeth) were divided into 4 groups (n=12) according to surface treatment: no polishing-coating (NP-C), conventional polishing (CP), Optiglaze (OG) coating, and PRIZMA seal (PS) coating. Surface roughness (Ra) and hardness were measured using a profilometer and Vickers hardness tester, respectively. The data was analyzed using one & two-way ANOVA, and post-hoc Tukey's tests (α=0.05).</p><p><strong>Results: </strong>For both DBR materials, polished and coated groups showed a significant decrease (p<0.001) in Ra compared to the unpolished group (ASIGA: 1.6±0.36 µm; NextDent: 1.13±0.17 µm). Coated groups had lower roughness than the polished group (p<0.05). Similarly, for both printed tooth resins, the unpolished group recorded the highest Ra values and differed significantly from the polished and coated groups (p<0.001). CP showed significantly higher Ra than OG and PS (p<0.001), with no significant difference between the two coated groups. Regarding hardness, no significant differences were found among unpolished, polished, and coated DBR groups (p>0.05), except for the OG group, which showed significantly higher hardness than other groups (p<0.001). Between the two resins, NextDent showed significantly higher hardness than ASIGA only in the OG group (p=0.009). The same trend was observed for printed teeth, where OG coating yielded the highest hardness values.</p><p><strong>Conclusion: </strong>Surface roughness of 3D printed DBR and denture teeth decreased after polishing and coatings. Coating using OG resin improved the hardness of DBR and denture teeth.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"46909"},"PeriodicalIF":0.0,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13636026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149119283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of bacterial exposure on the mechanical behavior of nickel-titanium open-coil springs.","authors":"Diego Paul Hidalgo Muñóz, Mauricio Aguirre Balseca, Marjory Elizabeth Vaca Zapata, Karina Maria Salvatore Freitas, Stalin Wladimir Tamami Tualombo","doi":"10.2340/biid.v13.46766","DOIUrl":"10.2340/biid.v13.46766","url":null,"abstract":"<p><strong>Objective: </strong>This <i>in vitro</i> study aimed to evaluate the effect of <i>Streptococcus mutans</i> on the force alteration of nickel-titanium (NiTi) open-coil springs under constant compression.</p><p><strong>Materials and methods: </strong>Sixty NiTi open-coil springs from three commercial brands (3M, Ormco, and American Orthodontics [AO]) were standardized to a resting length of 15 mm and compressed with a 240-g load using an Instron^® universal testing machine. Each brand was divided into control (immersed in artificial saliva) and experimental (exposed to <i>S. mutans</i> in Brain Heart Infusion medium) conditions. Samples were incubated at 37°C for 30 days, after which force levels at 0.5, 3.25, and 6.5 mm displacements were remeasured. Data were analyzed with paired <i>t</i>-tests, one-way analysis of variance, and Tukey's <i>post hoc</i> tests (<i>p</i> < 0.05).</p><p><strong>Results: </strong>All brands exhibited force increases after 30 days, though with heterogeneous patterns. 3M springs maintained relatively stable behavior, with consistent force increments across all displacements in both conditions. AO springs showed irregular responses, with losses at some displacements and substantial gains at others, especially under bacterial exposure. Ormco springs displayed the highest variability and most pronounced increases, with force gains exceeding 80 gf, suggesting possible microstructural modifications.</p><p><strong>Conclusions: </strong>Force stability in NiTi open-coil springs is brand-dependent and influenced by bacterial exposure. While 3M springs demonstrated predictable performance, AO and Ormco exhibited less consistent behavior, which may risk excessive force application during clinical use. These findings highlight the importance of considering biological and environmental factors in the selection and monitoring of NiTi coil springs.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"46766"},"PeriodicalIF":0.0,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13595418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sikri's Magnetic Attachment Retained Two-Tray (SMART) impression technique for prosthodontic management of a knife-edge residual ridge: a case report.","authors":"Arpit Sikri, Jyotsana Sikri, Rekha Thiruvengadam, Muthu Thiruvengadam","doi":"10.2340/biid.v13.46765","DOIUrl":"https://doi.org/10.2340/biid.v13.46765","url":null,"abstract":"<p><strong>Background: </strong>Mandibular knife-edge residual ridges present a significant challenge during complete denture impression making because of their narrow morphology and susceptibility to tissue distortion under pressure. This report describes the clinical application of the novel Sikri's Magnetic Attachment Retained Two-Tray (SMART) impression technique, conceptualized, developed, and patented by Dr. Arpit Sikri (Patent/ROC No. L-156844/2024), for obtaining an accurate mucostatic impression of a mandibular knife-edge residual ridge without the application of manual finger pressure. The SMART technique employs a magnetically retained split custom tray design that facilitates pressure-free tray stabilization and precise impression making in anatomically challenging mandibular residual ridges.</p><p><strong>Materials and methods: </strong>A completely edentulous patient with a pronounced knife-edge residual ridge in the anterior mandible was rehabilitated using the SMART impression technique. A custom-designed split two-part impression tray incorporating magnetic attachments for self-retention and retentive holes for impression material retention was fabricated. Magnetic attraction between the tray components ensured stable and reproducible tray positioning throughout the impression procedure, eliminating the need for operator-applied finger pressure and facilitating a pressure-free mucostatic impression of the residual ridge.</p><p><strong>Results: </strong>The SMART technique enabled accurate recording of the mandibular residual ridge anatomy without observable tissue displacement during impression making. The definitive impression produced a well-adapted master cast, resulting in a complete denture with satisfactory retention, stability, adaptation, and patient comfort during clinical evaluation.</p><p><strong>Conclusion: </strong>The SMART impression technique represents a simple, innovative, and clinically applicable approach for the prosthodontic management of mandibular knife-edge residual ridge. By eliminating manual tray stabilization and minimizing tissue displacement during impression making, it facilitates accurate mucostatic impressions and may improve denture fit, stability, and overall clinical performance. Further clinical studies involving larger patient populations are required to evaluate its reproducibility and long-term clinical effectiveness.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"46765"},"PeriodicalIF":0.0,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13580030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148992671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of tube cooling on the osteogenic activity of concentrated platelet-rich fibrin in human periodontal ligament cells.","authors":"Rucha Shah, Mavinakote Gowda Triveni, Baron Tarun Kumar, Raison Thomas, Hiral Karwa","doi":"10.2340/biid.v13.46669","DOIUrl":"10.2340/biid.v13.46669","url":null,"abstract":"<p><strong>Objective: </strong>To compare the effect of concentrated platelet-rich fibrin (C-PRF) immediately after collection to C-PRF kept in a cooling device for about 90 min on the proliferation, osteogenic differentiation, and mineralization in human periodontal ligament cells (hPDLCs).</p><p><strong>Methods: </strong>Ten milliliters of blood without anticoagulants was collected in two tubes from 12 systemically healthy male volunteers and subjected to centrifugation at 700 RCF (relative centrifugal force)-max for 8 min for the test groups. C-PRF was collected immediately from the tubes of the first group, whereas in the second group, the tube was maintained at 4°C prior to blood collection and centrifugation, and following centrifugation, it was returned to a cooling device at 4°C for 90 min. This was then co-cultured with hPDLCs for 21 days. Cell viability and alkaline phosphatase levels were assessed on days 1, 7, 14, and 21. At the end of 21 days, Alizarin Red staining was done to assess the formation of mineralized nodules. All outcome assessments were conducted in three groups: C-PRF, cooled C-PRF, and a control group comprising hPDLCs cultured in an osteogenic basal culture medium without C-PRF and without any intervention.</p><p><strong>Statistical analysis: </strong>Linear mixed-effects models were used to analyze values across groups and time points.</p><p><strong>Results: </strong>Both the C-PRF group and cooled C-PRF group demonstrated significantly higher cell proliferation and alkaline phosphatase levels than the control group at day 7 and day 14. However, there was no statistically significant difference between the C-PRF and cooled C-PRF groups when compared for cell proliferation and alkaline phosphatase production at days 1, 7, 14, and 21 (<i>p</i> > 0.05). At the end of 21 days, both groups demonstrated significantly higher mineralization than the control group (<i>p</i> < 0.05); however, there was no difference between the C-PRF and the cooled C-PRF groups.</p><p><strong>Conclusion: </strong>Usage of C-PRF after storage at 4°C up to 90 min does not significantly alter cell proliferation, alkaline phosphatase production, and mineralized nodule formation compared with conventional C-PRF in hPDLCs.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"46669"},"PeriodicalIF":0.0,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13551082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148914508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a silicon carbide bur on shear bond strength between resin cement and zirconia.","authors":"Khalil Aburawa, Kamel Al Hijazi, Christel Larsson, Martin Janda","doi":"10.2340/biid.v13.46767","DOIUrl":"10.2340/biid.v13.46767","url":null,"abstract":"<p><strong>Purpose: </strong>This in-vitro pilot study aimed to investigate the effect of a silicon carbide grinding bur on the shear bond strength (SBS) between zirconia and 10-MDP-containing cement.</p><p><strong>Materials and methods: </strong>Thirty zirconia specimens were prepared and randomly assigned to three groups based on surface pretreatment: airborne-particle abrasion with aluminum oxide particles (APA), treatment with a silicon carbide grinding bur (SiC bur), and airborne-particle abrasion followed by silicon carbide bur treatment (APA + SiC bur). All specimens were bonded with an adhesive resin cement (PANAVIA V5), aged with 5,000 thermocycles, and subjected to an SBS test. Statistical analysis was performed using one-way analysis of variance (ANOVA) and Tukey's post hoc test (α = 0.05). Fracture modes were assessed.</p><p><strong>Results: </strong>The APA group showed significantly higher SBS than the SiC bur and APA + SiC bur groups (<i>p</i> < 0.001). The APA + SiC bur group showed a higher mean SBS than the SiC bur group, but the difference was not statistically significant (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>Silicon carbide bur treatment did not have a beneficial effect on SBS after 5,000 thermocycles. Airborne-particle abrasion resulted in significantly higher SBS than silicon carbide bur treatment alone or airborne-particle abrasion followed by silicon carbide bur treatment.</p><p><strong>Clinical relevance: </strong>Under the tested conditions, the silicon carbide bur cannot be recommended as an alternative or an adjunct to airborne-particle abrasion for improving zirconia-resin cement bonding.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"46767"},"PeriodicalIF":0.0,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13525429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148857957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Marginal adaptation and fracture resistance of CAD/CAM-fabricated PMMA, PEEK, and PEKK three-unit provisional fixed dental prostheses: an in vitro comparative study.","authors":"Mustafa Mohammad Harfi, Shaimaa Ahmed Abo El-Farag, Ahmed Shams","doi":"10.2340/biid.v13.46737","DOIUrl":"10.2340/biid.v13.46737","url":null,"abstract":"<p><strong>Background: </strong>Although polymethyl methacrylate (PMMA) is widely used for computer-aided design and computer-aided manufacturing (CAD/CAM) provisional restorations, high-performance polymers such as polyetheretherketone (PEEK) and polyetherketoneketone (PEKK) have been proposed as alternatives. However, limited data are available comparing these materials in multi-unit provisional fixed dental prostheses (FDPs). This in vitro study aimed to evaluate and compare the marginal adaptation and fracture resistance of CAD/CAM-fabricated three-unit provisional FDPs constructed from PMMA, PEEK, and PEKK.</p><p><strong>Materials and methods: </strong>A total of 48 sound human maxillary teeth (24 second premolars and 24 second molars) were prepared to receive 24 CAD/CAM-fabricated three-unit provisional FDPs. Specimens were randomly assigned into three groups (<i>n</i> = 8) according to material: PMMA, PEEK, and PEKK. Marginal adaptation was initially measured before cementation using a stereomicroscope. Following cementation, all specimens underwent standardized thermomechanical aging (10,000 thermal cycles and 240,000 mechanical loading cycles), after which marginal adaptation was reevaluated. Fracture resistance was then assessed using a universal testing machine, followed by analysis with scanning electron microscopy. Data were statistically analyzed using two-way repeated-measures analysis of variance (ANOVA), one-way ANOVA, Tukey's post hoc test, and Fisher's exact test (<i>P</i> ≤ 0.05).</p><p><strong>Results: </strong>Following cementation and aging, PMMA showed significantly lower marginal discrepancy than PEEK and PEKK (<i>P</i> < 0.001). PEEK exhibited a significant improvement in marginal adaptation after thermomechanical aging (<i>P</i> = 0.002), whereas PMMA and PEKK showed no significant changes. Fracture resistance differed significantly among groups (<i>P</i> < 0.001), with PEKK recording the highest mean fracture load (2,669 ± 204 N), followed by PEEK (1,849 ± 183 N), while PMMA showed the lowest mean value (1,072 ± 127 N).</p><p><strong>Conclusions: </strong>Under the tested experimental conditions, material type significantly affected both marginal adaptation and fracture resistance. Among the tested materials, PMMA demonstrated the lowest marginal discrepancy, and PEKK exhibited the highest fracture resistance, whereas PEEK provided a balanced performance.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"46737"},"PeriodicalIF":0.0,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13525359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148857947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemical corrosion properties of a novel sodium hyaluronate and zinc oxide nanoparticle-coated stainless steel orthodontic arch wire - an in-vitro study.","authors":"Najiya V Pallikkara, Shweta Nagesh, Pugalmani Sivashanmugam, Shantha Sundari","doi":"10.2340/biid.v13.46738","DOIUrl":"10.2340/biid.v13.46738","url":null,"abstract":"<p><strong>Background: </strong>Nanoparticle-based surface modifications of orthodontic arch wires have been extensively investigated for antimicrobial and frictional properties. However, their effect on corrosion behaviour remains largely unexplored.</p><p><strong>Objectives: </strong>To evaluate the electrochemical corrosion resistance properties (corrosion potential [Ecorr], polarisation resistance [Rp], corrosion current density [icorr], corrosion rate [CR] and the impedance-derived charge-transfer resistance [Rct]) of zinc oxide and sodium hyaluronate (ZnO-SH)-coated and -uncoated stainless steel (SS) orthodontic arch wire in three simulated pH environments.</p><p><strong>Materials and methods: </strong>Thirty commercially available 19 × 25\" SS arch wires were divided into coated (<i>n</i> = 15) and uncoated (<i>n</i> = 15) groups. The samples were immersed in neutral, acidic and alkaline pH at 37°C for 2 h. Electrochemical testing included potentiodynamic polarisation and electrochemical impedance spectroscopy (EIS). Statistical comparison was done using Welch's t-test and two-way Analysis of variance (ANOVA) with Bonferroni-corrected post-hoc comparisons.</p><p><strong>Results: </strong>The effect of the ZnO-SH coating was strongly environment dependent, with a highly significant coating-to-environment interaction for all rate parameters (<i>p</i> < 0.001). In the neutral and alkaline environments, the coated wires showed significantly higher Rp and lower corrosion icorr and CR than the uncoated wires (<i>p</i> < 0.001). In the acidic medium, the opposite was observed: the uncoated wires had significantly higher Rp (822 vs. 91 kΩ·cm²) and significantly lower icorr (0.019 vs. 0.273 µA/cm²) than the coated wires (<i>p</i> < 0.001). Post-corrosion scanning electron microscopy confirmed an intact coating in the neutral and alkaline environments and extensive coating breakdown, pitting and cavitation in the acidic medium.</p><p><strong>Conclusion: </strong>The ZnO-SH coating improved the corrosion resistance of SS orthodontic arch wires in the neutral and alkaline but not in the acidic environment.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"46738"},"PeriodicalIF":0.0,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13501168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148815109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fracture strength of CAD/CAM glass fiber post-and-cores: a systematic review.","authors":"Amira Yousfi, Rihab Dakhli","doi":"10.2340/biid.v13.46724","DOIUrl":"10.2340/biid.v13.46724","url":null,"abstract":"<p><strong>Background/objectives/introduction: </strong>Endodontically treated teeth with extensive coronal tissue loss often require post-and-core restorations to provide retention and support for definitive restorations. Recent advances in computer-aided design/computer-aided manufacturing (CAD/CAM) technology have enabled the fabrication of customized glass fiber post-and-core systems with improved adaptation to root canal anatomy. However, evidence regarding their fracture strength remains inconsistent. This systematic review aimed to evaluate the fracture strength of CAD/CAM-fabricated glass fiber post-and-core systems, compare their performance with that of other post systems, and identify the factors influencing their fracture strength.</p><p><strong>Materials and methods: </strong>A systematic review was conducted according to PRISMA guidelines and registered in PROSPERO (CRD420251038278). Electronic searches were performed in PubMed, Scopus, Web of Science, and Cochrane Library in January 2025 and updated in February 2026. Studies evaluating the fracture strength of CAD/CAM glass fiber post-and-core systems were included. Data regarding study characteristics, materials, testing methods, aging procedures, fracture strength outcomes, failure modes, and principal findings were extracted. Methodological quality was assessed using a modified CONSORT checklist adapted for in vitro studies.</p><p><strong>Results: </strong>A total of 17 studies met the eligibility criteria. Fracture strength values varied considerably according to material composition, testing protocols, and experimental conditions. CAD/CAM glass fiber post-and core systems generally demonstrated fracture strength comparable to cast metal and other contemporary post systems. Improved adaptation to root canal anatomy and thinner cement layers were consistently reported. Although some materials exhibited higher fracture strength values, CAD/CAM glass fiber posts were frequently associated with more favorable and repairable failure modes.</p><p><strong>Conclusions: </strong>CAD/CAM-fabricated glass fiber post-and-core systems represent a promising alternative to conventional post systems, providing fracture strength comparable to established restorative options while promoting more favorable failure behavior. However, methodological heterogeneity among studies highlights the need for standardized testing protocols and further clinical investigations.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"46724"},"PeriodicalIF":0.0,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13495068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of NeoPUTTY and mineral trioxide aggregate for full pulpotomy in mature permanent molars with irreversible pulpitis: a randomized clinical study.","authors":"Shiwani Chawla, Ruchi Singhal, Ritu Namdev, Chanchal Kumari, Khusboo Chhanna","doi":"10.2340/biid.v13.46677","DOIUrl":"https://doi.org/10.2340/biid.v13.46677","url":null,"abstract":"<p><strong>Objective: </strong>To compare the clinical and radiographic outcomes of NeoPUTTY and mineral trioxide aggregate (MTA) as medicaments for full pulpotomy in mature permanent molars with irreversible pulpitis in children.</p><p><strong>Materials and methods: </strong>Forty-six mature permanent molars from 46 children aged 9-14 years (one tooth per child) were randomly allocated to NeoPUTTY (<i>n</i> = 23) or MTA (<i>n</i> = 23) groups. Full pulpotomy was performed under rubber dam isolation followed by immediate composite restoration. Clinical and radiographic outcomes were evaluated at 1, 3, 6, and 12 months and at 6 and 12 months, respectively. Postoperative pain was assessed at 24 h using a visual analog scale (VAS). Hemostasis time was recorded intraoperatively. Per-protocol analysis was performed using an independent <i>t</i>-test, Mann-Whitney U test, Chi-square test, and Fisher's exact test (<i>p</i> < 0.05). The trial was registered on ClinicalTrials.gov (NCT07702942).</p><p><strong>Results: </strong>Forty-four teeth (22 per group) completed the final analysis; one participant from each group was lost to follow-up. Mean VAS scores decreased significantly within 24 h in both groups (<i>p</i> < 0.001), from 6.48 ± 1.73 to 0.91 ± 1.12 (NeoPUTTY) and from 6.17 ± 1.47 to 0.65 ± 0.78 (MTA), with no significant intergroup difference. Overall success at 12 months was 95.5% in both groups (21/22; 95% confidence interval [CI]: 77.2-99.9; <i>p</i> = 1.000). Intra- and inter-examiner radiographic agreement was almost perfect (κ = 0.87 and 0.83). Treatment outcome was not significantly associated with jaw location, sex, pain duration, hemostasis time, caries depth, or Wolters pulpitis grade.</p><p><strong>Conclusion: </strong>Within the limitations of this study and 12-month follow-up, no statistically significant differences were detected between NeoPUTTY and MTA in postoperative pain reduction or clinical/radiographic success after full pulpotomy in mature permanent molars with irreversible pulpitis. Adequately powered non-inferiority or equivalence trials with longer follow-up are required to confirm these preliminary findings.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"46677"},"PeriodicalIF":0.0,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13483719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}