Biomaterial investigations in dentistry最新文献_第2页

An in vitro study on the influence of laser-activated irrigation on infiltration and leakage of a dual curing-resin cement as an endodontic sealer 关于激光激活灌洗对作为牙髓密封剂的双固化树脂水门汀的渗透和渗漏影响的体外研究

Biomaterial investigations in dentistry Pub Date : 2024-07-12 DOI: 10.2340/biid.v11.41098

L. Marger, M. Abdelaziz, E. Bella, I. Krejci, C. I. Anton Y Otero

{"title":"An in vitro study on the influence of laser-activated irrigation on infiltration and leakage of a dual curing-resin cement as an endodontic sealer","authors":"L. Marger, M. Abdelaziz, E. Bella, I. Krejci, C. I. Anton Y Otero","doi":"10.2340/biid.v11.41098","DOIUrl":"https://doi.org/10.2340/biid.v11.41098","url":null,"abstract":"Objectives: The study aims to investigate the effects of laser-activated irrigation on infiltration and microleakage of a dual-curing resin cement applied as a root canal sealer.\u0000Methods: Thirty-eight extracted upper molars were attributed to four experimental groups. Roots were mechanically enlarged and disinfected (NaOCl). Control samples (n = 11) were irrigated with conventional needles and three different lasers were used to activate the irrigant in the other groups (n = 9): 2.94 µm Er:YAG laser, 9,300 µm CO2 laser and 808 nm diode laser with a modified black coated laser tip. Final irrigation was performed in each group with ethylenediaminetetraacetic acid (EDTA), sodium hypochlorite (NaOCl) and sodium chloride (NaCl) activated with lasers and in the control without activation.Dentin tubules were then labeled with a red fluorophore (Rhodamine B) and the root canals were sealed with a dual-curing resin cement (Paracore). The cement fixed the dye on the sealed and infiltrated dentin parts. To remove the Rhodamine not fixed by the cement, roots were then sectioned horizontally and immersed in hydrogen peroxide (H2O2). The empty dentin tubules spaces were then labeled with a green fluorophore (Fluorescein) allowing the visualization of infiltration and microleakage by confocal microscopy.\u0000Results: Percentages of infiltration were significantly higher in the middle root third of the control and Er:YAG laser-activated samples compared to CO2 or diode laser groups. Microleakage was present in all experimental groups but significantly less after CO2 laser activation.\u0000Conclusion: Laser-activated irrigation impacted resin cement infiltration and microleakage dependent on the applied wavelength. Er:YAG laser activation led to higher values of infiltration and microleakage compared to CO2 and diode lasers.","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"67 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141653150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accumulation and removal of Streptococcus mutans biofilm on enamel and root surfaces in vitro 变异链球菌生物膜在牙釉质和牙根表面的体外积累和清除

Biomaterial investigations in dentistry Pub Date : 2024-07-12 DOI: 10.2340/biid.v11.41059

Anne Breivik, Aida Mulic, A. Sehic, H. Valen, S. Kopperud, Linda Stein, Qalbi Khan

{"title":"Accumulation and removal of Streptococcus mutans biofilm on enamel and root surfaces in vitro","authors":"Anne Breivik, Aida Mulic, A. Sehic, H. Valen, S. Kopperud, Linda Stein, Qalbi Khan","doi":"10.2340/biid.v11.41059","DOIUrl":"https://doi.org/10.2340/biid.v11.41059","url":null,"abstract":"Objective: This study aimed to quantitatively investigate the accumulation of Streptococcus mutans biofilm on enamel and root surfaces and assess the amount of biofilm removal using (1) experimental toothpaste and (2) water, in a closed system of flow chamber.\u0000Methods: Eight sound premolars were embedded in epoxy resin and polished with silicon carbide grinding papers to display enamel and root surfaces. To mimic biofilm, cultures of Streptococcus mutans were prepared and grown on the tooth surfaces over night before they were exposed to either 2 liters of Milli Q water or 2 liters of 40% experimental toothpaste in the flow chamber. The amount of biofilm was measured and quantified in Fluorescence microscopy. Mean fluorescence values were recorded and analysed using Microsoft® Excel® (MS Excel 2016).\u0000Results: The ability to grow biofilm was equally present at both the enamel and root surfaces. The use of water and 40% experimental toothpaste showed a significant reduction of areas covered with biofilm on both enamel and root dentin in comparison to untreated surfaces (p < 0.01). Significantly more biofilm was removed from enamel compared to root surfaces when treated with either water and toothpaste (p < 0.01). Slightly less biofilm was removed by the use of water compared to toothpaste on both enamel and root dentin surfaces, although the differences were not statistically significant.\u0000Conclusion: The results indicate that less biofilm is removed from the root surfaces than enamel by the use of water and 40% experimental toothpaste in flow chamber. Assessing oral biofilm accumulation and monitoring biofilm formation on enamel and root dentin surfaces give oral health professionals important directions that could strenghten the significance of dental caries prevention. Improving older individuals’ oral hygiene practices should therefore be considered an important measure to prevent root caries.","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141654108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the influence of titanium particle size and concentration on osteogenic response of human osteoblasts – in vitro study 探究钛颗粒大小和浓度对人类成骨细胞成骨反应的影响--体外研究

Biomaterial investigations in dentistry Pub Date : 2024-06-13 DOI: 10.2340/biid.v11.40843

S. Sheela, Waad Kheder, Rani Samsudin

{"title":"Investigating the influence of titanium particle size and concentration on osteogenic response of human osteoblasts – in vitro study","authors":"S. Sheela, Waad Kheder, Rani Samsudin","doi":"10.2340/biid.v11.40843","DOIUrl":"https://doi.org/10.2340/biid.v11.40843","url":null,"abstract":"Purpose: The purpose of this study was to investigate the correlation between the size and concentration of titanium particles and the osteogenic response of human osteoblasts (HOB). \u0000Materials and Methods: Different concentrations of titanium dioxide nano- and micro-particles were prepared and their biocompatibility on HOBs was analyzed using XTT assay. The changes in the actin cytoskeletal organization were studied by confocal laser scanning microscopy. The generation of intracellular reactive oxygen species (ROS) by HOBs after exposure to titanium dioxide particles was analyzed using ROS assay. Besides, the osteogenic potential represented by alkaline phosphatase activity, osteoprotegerin, macrophage colony stimulating factor levels, and biomineralization were analyzed.\u0000Results: Short-term interaction of titanium dioxide nano- and micro-particles did not induce toxicity to HOBs. However, cells treated with 100 μg/mL titanium dioxide nano- and micro-particles demonstrated higher ROS generation compared to control. Besides, cells treated with 100 µg/mL titanium dioxide nanoparticles showed higher alkaline phosphatase activity, osteoprotegerin, macrophage colony stimulating factor levels and biomineralization compared to titanium dioxide microparticles. \u0000Conclusion: Collectively, the study found titanium dioxide nanoparticles to be more biocompatible than microparticles providing an insight into the capability of nanostructures in supporting osteoblast differentiation and its plausibility in biomedical applications.","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141349645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological properties versus solubility of endodontic sealers and cements 牙髓密封剂和水门汀的生物特性与可溶性

Biomaterial investigations in dentistry Pub Date : 2024-06-04 DOI: 10.2340/biid.v11.40863

Inge Fristad, Sivakami Haug, A. Bårdsen

引用次数: 0

An in vitro evaluation of endodontic sealers and an antibiotic to assess their antimicrobial effect against Enterococcus faecalis 体外评估牙髓密封剂和抗生素对粪肠球菌的抗菌效果

Biomaterial investigations in dentistry Pub Date : 2024-05-24 DOI: 10.2340/biid.v11.40646

Elizabeth Madla-Cruz, Vanascheck Dasaev Villanueva-Pérez, Myriam A. De la Garza-Ramos, J. Flores-Treviño, Idalia Rodríguez-Delgado, Fanny López-Martinez

{"title":"An in vitro evaluation of endodontic sealers and an antibiotic to assess their antimicrobial effect against Enterococcus faecalis","authors":"Elizabeth Madla-Cruz, Vanascheck Dasaev Villanueva-Pérez, Myriam A. De la Garza-Ramos, J. Flores-Treviño, Idalia Rodríguez-Delgado, Fanny López-Martinez","doi":"10.2340/biid.v11.40646","DOIUrl":"https://doi.org/10.2340/biid.v11.40646","url":null,"abstract":"ObjectiveThis study aimed to compare the antimicrobial effect of three endodontic sealers (AH Plus, Mineral trioxide aggregate [MTA] Fillapex, and BioRoot RCS) with and without amoxicillin against E. faecalis. \u0000MethodologyAmoxicillin, equivalent to 10% of the sealers’ total weight, was mixed with the sealers. Another batch was prepared without amoxicillin. The direct contact test (DCT) and the agar diffusion test were used to assess the antibacterial effect. Results were analysed using one-way analysis of variance (ANOVA), the F-test, and the Kruskal-Wallis test. \u0000ResultsAH Plus significantly suppressed E. faecalis without the addition of amoxicillin in the DCT (p = 0.011), while in the agar diffusion test, BioRoot RCS had a larger inhibition zone than the control (p < 0.001). When amoxicillin was added to the sealers, AH Plus (p = 0.003) and MTA Fillapex (p = 0.042) reduced E. faecalis growth. In contrast, all three sealers showed larger inhibition zones than the control (p = 0.001), with AH Plus displaying a larger inhibition zone than MTA Fillapex (p = 0.042) and BioRoot RCS (p = 0.032). \u0000ConclusionsIt was thus concluded that the addition of amoxicillin to endodontic sealers enhances their antimicrobial activity against E. faecalis.","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"6 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141099550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of orthodontic bracket base shape on shear bond strength to human enamel, an in vitro study 正畸托槽基底形状对人体珐琅质剪切粘接强度的影响，体外研究

Biomaterial investigations in dentistry Pub Date : 2024-05-07 DOI: 10.2340/biid.v11.40585

Ziana Esmail, William Wiltshire, Fabio H. S. L. Pinheiro, C. M. Frota, Rodrigo França

{"title":"The effect of orthodontic bracket base shape on shear bond strength to human enamel, an in vitro study","authors":"Ziana Esmail, William Wiltshire, Fabio H. S. L. Pinheiro, C. M. Frota, Rodrigo França","doi":"10.2340/biid.v11.40585","DOIUrl":"https://doi.org/10.2340/biid.v11.40585","url":null,"abstract":"The purpose of this study was to evaluate the in vitro effect of orthodontic bracket base shape on shear bond strength (SBS) to human enamel and assess the nature of debonding fractures using the Adhesive Remnant Index (ARI). Orthodontic brackets with different-shaped bases (flower, heart, rectangle) were bonded to 120 extracted human third molars. Shear bond strength was measured using a Servohydraulic Test System at 24 h and 2 months after bonding. Adhesive Remnant Index scores were evaluated under 10x magnification to assess the amount of resin left on the tooth. The control bracket (rectangular base shape) had the highest mean SBS (26.8 ± 8.2 megapascals [MPa]), and significantly differed from the flower (17.2 ± 4.4 MPa) and heart (18.9 ± 3.5 MPa) base shapes (p < 0.001). The mean SBS between debonding times at 24 h (21.5 ± 7.4 MPa) and 2 months (20.4 ± 6.7 MPa) were not statistically significant (p > 0.05). Analysis of ARI scores showed a significant difference between flower-24 h versus heart-2 months (p = 0.039), flower-24 h versus heart-24 h (p = 0.004), and control-2 months versus heart-24 h (p = 0.015). Bracket base shape influenced SBS, with the rectangular base shape having a higher mean SBS compared to flower and heart base shapes. Variations in ARI scores occurred based on bracket shape and were of a mixed adhesive-cohesive nature. All bracket shapes had bond strengths above the clinically acceptable range of 6–8 MPa, and may thus provide adequate SBS in a clinical situation. ","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"7 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141003929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of different beverages and polishing techniques on colour stability of CAD/CAM composite restorative materials. 不同饮料和抛光技术对 CAD/CAM 复合修复材料颜色稳定性的影响。

Biomaterial investigations in dentistry Pub Date : 2024-04-26 eCollection Date: 2024-01-01 DOI: 10.2340/biid.v11.40591

Lippo Lassila, Mine B Uctasli, Kanae Wada, Pekka K Vallittu, Sufyan Garoushi

{"title":"Effect of different beverages and polishing techniques on colour stability of CAD/CAM composite restorative materials.","authors":"Lippo Lassila, Mine B Uctasli, Kanae Wada, Pekka K Vallittu, Sufyan Garoushi","doi":"10.2340/biid.v11.40591","DOIUrl":"10.2340/biid.v11.40591","url":null,"abstract":"Objectives: The aim of this article was to compare the colour stability of short fibre-reinforced computer-assisted design/computer-assisted manufacturing (CAD/CAM) composite (SFRC CAD) to commercially available CAD/CAM materials following prolonged immersion in a variety of beverages. Furthermore, the influence of the polishing technique was evaluated.Materials and methods: A total of 120 rectangular specimens (10 mm length × 14 mm width × 2 mm thickness) were prepared from SFRC CAD, IPS e-max, Cerasmart 270, Celtra Duo, Enamic, and Brilliant Crios. The specimens underwent polishing through either a laboratory polishing machine equipped with 4000-grit silicon carbide paper or chairside polishing using Sof-Lex spiral. Twenty specimens of each tested CAD/CAM material were randomly divided into four groups (n = 5) based on the staining solution used in order to evaluate the colour stability of the materials. Group 1: distilled water, Group 2: coffee, Group 3: red wine, Group 4: coke. Using a spectrophotometer, the colour changes (∆E) of all CAD/CAM materials were assessed at baseline, and after 1 and 12 weeks of staining. Three-way analysis of variance was used to analyse the data (α = 0.05).Results: The staining solution and material type showed a significant influence on the CAD/CAM specimens' colour stability (p < 0.05), while polishing method had no significant influence (p > 0.05). The average ∆E values for specimens submerged in wine were considerably higher (p < 0.05) than those for the other solutions. SFRC CAD, Cerasmart 270, and Enamic displayed the highest ∆E values in wine (p < 0.05).Conclusions: The colour stability of tested SFRC CAD was comparable to other composite-based CAD/CAM materials, while IPS e.max exhibited the highest level of colour stability.","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"11 ","pages":"40591"},"PeriodicalIF":0.0,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11171852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141319145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An in-vitro study on effects of laser activation on dye penetration in human root dentin 关于激光激活对人牙根染色渗透影响的体外研究

Biomaterial investigations in dentistry Pub Date : 2024-04-05 DOI: 10.2340/biid.v11.40311

Clara Isabel Anton y Otero, L. Marger, E. di Bella, A. Feilzer, I. Krejci, M. Abdelaziz

{"title":"An in-vitro study on effects of laser activation on dye penetration in human root dentin","authors":"Clara Isabel Anton y Otero, L. Marger, E. di Bella, A. Feilzer, I. Krejci, M. Abdelaziz","doi":"10.2340/biid.v11.40311","DOIUrl":"https://doi.org/10.2340/biid.v11.40311","url":null,"abstract":"Objective To evaluate the penetration of a dye in root dentin after activation with different laser wavelengths. Materials Palatal roots of 38 human molars were enlarged and disinfected. Irrigation activation was performed with an Er:YAG laser: @50 mJ, 15 Hz (Er:YAG); a 9.3 µm CO2 laser: @40% power (CO2); diode lasers 455 nm/970 nm: @0.8 W, 15 Hz (D455, D970) and 808/980 nm: @1 W (D808, D980) and compared to positive control: etching with 35% H3PO4 (POS); negative control: water (NEG) and conventional needle irrigation: NaOCl and ethylenediaminetetraacetic acid (EDTA) (CONV). Methylene blue solution was introduced in the canal and laser-activated or left untouched for 100 s before the roots were dried and cut into horizontal slices. Dye penetration was automatically calculated by color recognition of two samples per root third (n = 8 per group in each coronal, middle and apical root thirds). The presence and absence of a smear layer was checked in two additional samples of the negative and positive control under scanning electron microscopy (SEM). Results Full-depth infiltration was not achieved in any group. Dye penetration in CONV was significantly less than in Er:YAG, CO2, POS, D455, D970, D808 and similar to NEG and D980 when results of different root thirds were pooled. Conclusion Laser activation using certain parameters enhanced dye penetration compared to conventional needle irrigation with NaOCl and EDTA (CONV).","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"8 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140738722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The power of light – From dental materials processing to diagnostics and therapeutics 光的力量 - 从牙科材料加工到诊断和治疗

Biomaterial investigations in dentistry Pub Date : 2024-03-18 DOI: 10.2340/biid.v11.40308

Mohammed A. Hadis, A. Shortall, William M. Palin

{"title":"The power of light – From dental materials processing to diagnostics and therapeutics","authors":"Mohammed A. Hadis, A. Shortall, William M. Palin","doi":"10.2340/biid.v11.40308","DOIUrl":"https://doi.org/10.2340/biid.v11.40308","url":null,"abstract":"Harnessing the power of light and its photonic energy is a powerful tool in biomedical applications. Its use ranges from biomaterials processing and fabrication of polymers to diagnostics and therapeutics. Dental light curable materials have evolved over several decades and now offer very fast (≤ 10 s) and reliable polymerization through depth (4–6 mm thick). This has been achieved by developments on two fronts: (1) chemistries with more efficient light absorption characteristics (camphorquinone [CQ], ~30 L mol-1 cm1 [ʎmax 470 nm]; monoacylphosphine oxides [MAPO], ~800 L mol-1 cm-1 [ʎmax 385 nm]; bisacylphosphine oxide [BAPO], ~1,000 L mol-1 cm-1 [ʎmax 385 nm]) as well mechanistically efficient and prolonged radical generation processes during and after light irradiation, and; (2) introducing light curing technologies (light emitting diodes [LEDs] and less common lasers) with higher powers (≤ 2 W), better spectral range using multiple diodes (short: 390–405 nm; intermediate: 410–450 nm; and long: 450–480 nm), and better spatial power distribution (i.e. homogenous irradiance). However, adequate cure of materials falls short for several reasons, including improper selection of materials and lights, limitations in the chemistry of the materials, and limitations in delivering light through depth. Photonic energy has further applications in dentistry which include transillumination for diagnostics, and therapeutic applications that include photodynamic therapy, photobiomodulation, and photodisinfection. Light interactions with materials and biological tissues are complex and it is important to understand the advantages and limitations of these interactions for successful treatment outcomes. This article highlights the advent of photonic technologies in dentistry, its applications, the advantages and limitations, and possible future developments.","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"54 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140232372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of cytotoxicity and antibacterial activity of different pulp capping liners 评估不同纸浆盖衬的细胞毒性和抗菌活性

Biomaterial investigations in dentistry Pub Date : 2023-12-27 DOI: 10.1080/26415275.2023.2287019

Zohre Moradi, Mahdi Abbasi, A. Bahador, Mir Saeed Yekaninejad, Xaniar Mohammadi Khanghah, Amirahmad Pahlavan Hoseini, Ladan Ranjbar Omrani

{"title":"Evaluation of cytotoxicity and antibacterial activity of different pulp capping liners","authors":"Zohre Moradi, Mahdi Abbasi, A. Bahador, Mir Saeed Yekaninejad, Xaniar Mohammadi Khanghah, Amirahmad Pahlavan Hoseini, Ladan Ranjbar Omrani","doi":"10.1080/26415275.2023.2287019","DOIUrl":"https://doi.org/10.1080/26415275.2023.2287019","url":null,"abstract":"Abstract This study compares the cytotoxicity and antibacterial activity of five pulp capping liners. This in vitro study was conducted on Fuji II LC glass ionomer, Dycal, Calcimol LC, TheraCal LC, and ACTIVA BioACTIVE. For cytotoxicity, the (MTT) methyl thiazolyl tetrazolium assay was performed on 3 samples from each group of human dental pulp cells (HDPSCs) after 24 h of incubation. The direct contact test (DCT) for antibacterial activity, 6 samples (3 for each material, and 3 for negative control), from each liner were made to evaluate Streptococcus mutans (S. mutans), Lactobacillus casei (L. casei), and Lactobacillus acidophilus (L. acidophilus). Data were analyzed by one-way ANOVA and Tukey’s post-hoc test (alpha = 0.05). Data analysis showed that the cytotoxicity of the materials was significantly different (p < 0.001). Fuji II LC and ACTIVA BioACTIVE showed strong cytotoxicity, TheraCal LC moderate cytotoxicity, and Dycal and Calcimol LC slight cytotoxicity. The analysis also revealed a significant difference among the materials regarding antibacterial activity (p < 0.001). Tukey’s test showed that the mean percentage of reduction in colony count was significant for all liners compared with the positive control (p < 0.001). The mean percentage of reduction in colony count for Dycal was significantly greater than that of Fuji II LC (p = 0.014), Calcimol LC (p = 0.003), and TheraCal LC (p = 0.001). ACTIVA BioACTIVE did not significantly differ from the other materials as regards antibacterial activity. Dycal showed significantly higher antibacterial activity than the other materials.","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"55 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139154358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0